NIH Chemical Genomics Center

Discovering the
Pathway Between
Chemistry and Biology

Welcome to the National Institutes of Health (NIH) Chemical Genomics Center (NCGC), a member of the Molecular Libraries Probe Production Center Network. This center has been established by the NIH to create a national resource in chemical probe development. The center uses the latest industrial-scale technologies to collect data that is useful for defining the cross-section between chemical space and biological activity. To learn more about our mission and operations, please spend some time visiting the links above.

>> Recent News

April 27, 2011 //
NIH Researchers Create Comprehensive Collection of Approved Drugs to Identify New Therapies for Rare and Neglected Diseases. [>> more]

October 8, 2010 //
NCGC Participates in the Second Annual 'Frontiers in Science and Medicine Day.' [>> more]

August 3, 2010 //
NIH Takes On New Role in Fight Against Rare Diseases. [>> more]

July 30, 2010 //
The Inaugral Development of Robust Experimental Assay Methods (aDREAM) Conference is Open for Registration. [>> more]

July 19, 2010 //
Tox21 collaboration between NCGC, NTP, and EPA expands to include FDA. [>> more]

>> Recent Publication

Dec, 2008 //
Beller JA, et al in PLoS Biology. COPI Complex Is a Regulator of Lipid Homeostasis [>> more]

July, 2008 //
Auld DS, et al in ACS Chemical Biology. A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays [>> more]

April, 2008 //
Readinger JA, et al in PNAS. Selective targeting of ITK blocks multiple steps of HIV replication [>> more]

March, 2008 //
Sayed AA, Simeonov A, et al in Nature Medicine. Identification of oxadiazoles as new drug leads for the control of schistosomiasis [>> more]

>> Assay Guidance Manual

Version 6.0 //
The Latest Version of the Assay Guidance Manual is now a Wiki
[>> more]

Version 5.0 //
The Latest Version of the Assay Guidance Manual Provides a Wealth of Resources
[>> more]