SysBioSIG is an NIH Special Interest Group (SIG) that sponsors activities exploring the diverse aspects of Systems Biology. SysBioSIG hosts the Systems Biology Speaker Series and is initiating a quarterly Workshop series to exchange ideas between scientists active in Systems Biology. A working definition of Systems Biology is "A research approach that seeks to describe the overall behavior of a biological system through detailed, quantitative experimentation combined with conceptual or computational modeling of the system´┐Żs components and their interactions." The complexity of the components' interactions and, in large systems, the quantities of relevant biological entities frequently requires the use of computational methods to analyze the data or simulate the systems of interest.

(Intramural) Systems Biology Symposium
Registration required and closed
Organizers: Michelle Bennett, Mark Knepper, Alan Michelson, Keji Zhao
  Session One Chair: Keji Zhao
8:25 AMRobert BalabanWelcome Introduction
8:30Robert BalabanSystems Biology of Mitochondrion
9:00Tish MurphyRegulation of Cardiac Metabolism
9:30Aleksandra Nita-LazarQuantitative, systematic analysis of protein expression changes during osteoclast differentiation from macrophages
10:00-10:30Coffee Break
  Session Two Chair: Mark Knepper
10:30Mark KnepperGlobal assessment of protein degradation and translation rates using LC-MS/MS
11:00Susan HarbisonGenome-wide association study of sleep in Drosophila melanogaster
11:30pmBrian OliverGene dose effects and compensation in Drosophila
12:00-1:15Lunch Break
  Session Three Chair: Tish Murphy
1:15Chris AustinHigh-throughput screening of chemicals and siRNAs for systems biology
1:45John TsangUsing natural human variations to study microRNA functions and immune responses in vivo
2:15Daniel LarsonSingle-Cell Measurement and Modulation of Steroid Receptors with Light
2:45Coffee Break
  Session Four Chair: Alan Michelson
3:00Alan MichelsonToward a systems-level understanding of developmental regulatory networks
3:30Teresa PrzytyckaUntangling heterogeneity: from single-cell variations to cancer
4:00Keji ZhaoEpigenomics of cellular differentiation
4:30-4:35Keji ZhaoClosing remarks

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Updated 1/16/12. Please email SysBioSIG_Info with questions or suggestions.