A. Administrative:

1. Guidelines for Preparing USDA Annual Reports and Assigning USDA Pain & Distress Categories, Revised 11/14/12. (PDF Document, 12 pages)

2. Guideline for Animal Medical Record Keeping and Transfer of Records Between NIH Intramural Animal Facilities, Approved 05/11/11 (PDF Document, 4 pages)

B. Animal Care Procedures:

1. NIH Animal Transportation Guidelines, Revised, 11/14/12.
   1a. Guidelines for NIH Rodent Transportation (PDF Document, 4 pages)
   1b. Guidelines for NIH Non-Rodent Transportation (PDF Document, 4 pages)

2. Guidelines for Survival Bleeding of Mice and Rats, Revised 09/12/12. (PDF Document, 7 pages)

3. Guidelines for the Genotyping of Mice and Rats, Revised 05/12/10. (PDF Document, 2 pages)

4. Guidelines for the Euthanasia of Rodent Feti and Neonates, Revised 03/09/11. (PDF Document, 3 pages)

5. Guidelines for Euthanasia of Rodents Using Carbon Dioxide, Revised 05/12/10. (PDF Document, 2 pages)

6. Guidelines for Survival Rodent Surgery, Revised 09/12/12. (PDF Document, 6 pages)

7. Guidelines for Diet Control in Behavioral Animal Studies, Revised 01/12/11. (PDF Document, 8 pages)

8. Guidelines for the Use of Adjuvants in Research, Revised 11/13/10. (PDF Document, 5 pages)

9. Guidelines for Toe Clipping of Rodents, Revised 05/12/10. (PDF Document, 1 page)

10. Guidelines for Ascites Production in Mice, Revised 05/12/10. (PDF Document, 2 pages)

11. Guidelines for Egg and Oocyte Harvesting in Xenopus laevis, Revised 07/14/10. (PDF Document, 2 pages)

12. Guidelines for Pain and Distress in Laboratory Animals: Responsibilities, Recognition and Alleviation, Revised 11/14/12. (PDF Document, 7 pages)

13. Guidelines for the Use of Non-Pharmaceutical Grade Compounds in Laboratory Animals, Revised 12/08/10 (PDF Document, 2 pages)

14. Guidelines for Use of Zebrafish in the NIH Intramural Research Program, Approved 03/11/09. (PDF Document, 4 pages)

15. Guidelines for the Establishment and Use of Mouse Breeding Groups, Approved 07/11/12.  (PDF Document, 1 page)

C. Animal Care & Use Committee:

1. Guidelines on Classifying Deficiencies Identified During Semiannual Reviews, Revised 05/11/11. (PDF Document, 2 pages)

2. Guidelines for Responding to Animal Care & Use Complaints from Outside NIH, Reapproved 01/09/13. (PDF Document, 3 pages)
   2a. Attachment - DDIR Memorandum, Revised 03/26/10. (PDF Document, 1 page)

3. Guideline Regarding Significant Changes to Animal Study Proposals, Revised 02/11/09. (PDF Document, 2 pages)

4. Guidelines for Institute/Center Collaborations involving Animal Activities Performed inside NIH Laboratories, Core or Shared Facilities, Revised 07/14/10. (PDF Document, 5 pages)

5. Guidelines for ACUC Oversight of Animal Activities in Shared and Central Facilities, Revised 12/08/10. (PDF Document, 2 pages)

6. Guidelines for Endpoints in Animal Study Proposals, Revised 05/11/11. (PDF Document, 7 pages)

7. Guideline for Review, Approval, & Post Approval Monitoring of Animal Study Proposals Including Designated Member Review, Revised 05/12/12. (PDF Document, 6 pages)

8. Guidelines for ACUC Oversight of Satellite Facilities, Study Areas, Laboratories and other Animal Activity Areas, Revised 05/12/12. (PDF Document, 1 page)

9. Guidelines for ACUC Membership, Revised 09/12/12 (PDF Document, 2 pages)

10. Guideline for Completing the NIH Intramural Animal Study Proposal Form, Approved, 07/11/2012. (PDF Document, 16 pages)

11. Guidelines for the Select Use of Expired Medical Products, Approved 11/09/11. (PDF Document, 1 page)
    
    
12. Guidelines for the Use of Preservative-Free Pharmaceuticals and Parenteral Fluids in Laboratory Animals, Approved 01/11/12. (PDF Document, 2 pages)

D. Facility Management:

1. Guidelines for Housing Multiple Species of Large Laboratory Animals, Revised 11/14/12. (PDF Document, 5 pages)

2. Guidelines for Personnel Protection and Minimum Requirements for Protective Clothing in Animal Facilities, Revised 12/18/07. (PDF Document, 12 pages)

3. Guidelines for the Prevention and Control of Tuberculosis in Nonhuman Primates, Revised 05/12/10. (PDF Document, 7 pages)

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This page is maintained by the Office of Animal Care and Use (OACU). Readers are encouraged to forward comments and suggestions to OACU at (301) 496-5424.
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