Cryogenic tanks filled with liquid nitrogen and millions of vials of frozen cells. Credit: Coriell Institute for Medical Research.
The NIGMS Human Genetic Cell Repository houses a collection of well-characterized, high-quality human cells for use in biomedical research. Established by NIGMS in 1972 and housed at the Coriell Institute for Medical Research in Camden, New Jersey, the repository now contains more than 10,000 cell lines. The collection includes cell lines—and DNA derived from these cell lines—acquired from individuals with inherited diseases, apparently healthy individuals, and individuals of diverse geographic origins. More than 1,000 diseases and 40-plus population groups are currently represented in the repository. Recently, the repository has launched a new collection of induced pluripotent stem (iPS) cell lines that carry disease gene mutations as well as normal control iPS cell lines.
The NIGMS cell repository Web site includes a list of collections, ordering information, sample submission instructions and frequently asked questions.