Question ID: WS-66
Submitted by: Anil Wali
February 25, 2011
How can we integrate best practices of eastern traditional medicine, incidence, prevalance and mortality rates seen among global populations with our current standard of care in cancer continuum. Background:There are many instances where prevalance of certain cancers are quite low in East Asian countries due to their dietary intake of spices and supplements that have anti-inflammatory properties. Prostate cancer would be nice example. The prologed use of these dietary practices from early childhood to adult life seem to have profound effect on the well being of majority of the population. It has been well documented fact that migration of these populations to US and acculturation with new dietary practices somehow increase their risk of developing malignancies. It could be partially due to the influence of gene environment interactions, stress and several other biological and non-biological factors. Feasibility:How could this complex problem with complicated disease etiology and pathogenesis be addressed in a simple pragmmatic way. We have made phenominal advances in the field of early detection, stem cells, imaging, targeted therapies based on pharmacogenomics but only incremental advances in prevention of the cancer for last 40 years. Addressing risk behaviors and excercise alone are not enough for "At-Risk" and "High-Risk" populations who are susceptible for developing cancer over their life time. Implications of Success:A global initiative led by NCI that would initiate partnerships with Insitutions of Excellence in Eastern Asain countries that have accumulated myriad of published data and clinical best practices in various types of malignancies. It would be a worthwhile effort to initiate scientific dialogue among scientists from these countries to foster synergy among trans-disciplinary approaches practiced here in USA to combat dreaded insiduous disease like cancer.
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