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Question ID: WS-83
Submitted by: Isis Mikhail
April 6, 2011

Why are we not studying "outliers" or "rarities" in more depth epidemiologically and else? This may help us understand some of the causes of cancer that we have not paid much attention to in the past. For example, studying heavy long-term smokers who do not develop cancer. Or looking at a cancer rare in one population that is more common in another population. For example breast cancer rate in males is about <1% in the US and higher in Africa as its rate is about 15% among men in Zambia. I believe we have new statistical methods that can help overcome the small sample size and related research challenges.

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