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Revision History for the Hematopoietic Project

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May 23, 2012

Data Revisions

These data changes are reflected in both the web-based database and the stand-alone software.

  • 2012 Data (May 21, 2012)
    • For disease 9659/3 Nodular lymphocyte predominant Hodgkin lymphoma, the ”[OBS] see 9651/3” has been removed.  This is not an obsolete term.
    • Change to the transformation data for “Solitary plasmacytoma of bone” to “9732/3 Multiple Myeloma”.
    • Changed code 9680 to add “Cytology (for primary CNS lymphoma only)” to the definitive diagnosis section.
  • 2010 Data (May 16, 2012)
    • Many of the diseases had additional primaries added to their “Same Primaries” field. This is why the ‘Data last updated’ date is May 16, 2012.

2012 Manual Revisions (version 2.1)

These data changes are reflected in both the web-based database and the stand-alone software.

  • Rule M12 on page 72: deleted the text “Simultaneously or”.
  • PH 16 on page 79: the code for DLBCL was changed from 9698/3 to 9680/3.
  • Appendix A on page 101: the code 9751/3 was changed to 9754/3.
  • Appendix D on page 117-118: ALK Positive Large B-Cell Lymphoma 9737/3 was added to the Alphabetic and Numeric List.

Web-based Database

  • The capability to switch from the 2012 to the 2010 data and manual.
  • The following ICD-O-3 Code Lists have been added to the site and can be sorted, printed, and exported:
    • ICD-O-3 codes
    • ICD-O-3 codes with their corresponding ICD-9 codes
    • ICD-O-3 codes with their corresponding ICD-10 codes
    • ICD-9 codes with their corresponding ICD-O-3 codes
    • ICD-10 codes with their corresponding ICD-O-3 codes

Software Revisions (version 2.1)

  • The capability to switch from the 2012 to the 2010 data and manual.

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May 4, 2012

Manual Revisions

This is a summary of the changes in the 2012 Hematopoietic Manual. Changes such as correcting typographical errors, breaking one of the modules into two modules, and updating the notes, “This is a change from previous rules” to “This is a change from pre-2010 rules”, are not included in this outline.

Introduction: Three new paragraphs

  1. Transformations: Chronic Neoplasm to Acute Neoplasm
  2. Steps in Priority Order for Using the Heme DB and Hematopoietic Coding Manual
  3. Other Treatment: Reporting Phlebotomy, Blood-Thinners/Anti-Clotting Medications, and Transfusions as treatment

Case Reportability Instructions: Revised

Multiple Primary Rules – Flowchart / Matrix / Text:

  1. Note 1 preceding rules (explaining the definition of chronic and acute neoplasms).
  2. Note 2 preceding rules (guidelines for NOS terminology).
  3. M2: Notes and Examples updated to include information on lymph nodes and timing rules.
  4. M3: New rule for sarcoma and leukemia with the same lineage.
  5. M4: New rule for multiple MDS subtypes to be consistent with the Heme Database.
  6. M5: FL and DLBCL changed to be consistent with Module 6 in the PH rules for FL and DLBCL.
  7. M6: Added specific guidelines for two or more types of non-Hodgkin lymphoma present in the same anatomic location. Expanded Notes and Examples.
  8. M7: Added specific guidelines for both Hodgkin and non-Hodgkin lymphoma in the same anatomic location. Expanded Notes and Examples.
  9. M8: Added guidelines for Hodgkin and non-Hodgkin lymphoma in different anatomic sites. Updated Notes and Examples.
  10. M9: Based on 2010 M6 rule. Expanded Notes and Examples.
  11. M10: Based on 2010 M7 rule. Added documentation of lymph node biopsies, or tissue biopsies. Notes include the 21 day rule.
  12. M11: Based on 2010 M9 rule. Expanded Notes and Examples.
  13. M12: Based on 2010 M10 rule, excluded ‘blast’ terminology.
  14. M13: Based on 2010 M8 rule. Added documentation of lymph node biopsies, or tissue biopsies.
  15. M14: Based on 2010 M11 rule. Updated Notes and Examples.
  16. M15: Based on 2010 M12 rule. Updated Notes and Examples.
  17. M16: Based on 2010 M13 rule with updated M rule numbers.

Primary Site and Histology Rules – Flowchart / Matrix / Text:

  • General instructions for coding histology and primary site taken out of Module 1. Instructions now precede the rules.
  • NEW: Instruction 5: Do not use ambiguous terms to code a specific histology.

Module 1: PH1 and PH2

  1. NEW Module: Coding guidelines for post-transplant lymphoproliferative disorders.
  2. PH1: New Rule: Added post-transplant lymphoproliferative disorder coding guidelines. Added Notes and Examples.
  3. PH2: New Rule: Added guidelines for coding post-transplant lymphoproliferative disorder when the diagnosis includes non-Hodgkin lymphoma, Hodgkin, or plasmacytoma. Added Notes and Examples.

Module 2: PH3 – PH7

  1. PH3: REVISED: Based on 2010 PH4, added plasma cell neoplasm to inclusion list. Updated Notes and Examples.
  2. PH4: REVISED: Based on 2010 PH5 rule. Regrouped diagnoses. Updated Notes and Examples.
  3. PH5: New Rule: Based on 2010 PH6 rule. Changed Primary site code and expanded Notes and Examples.
  4. PH6: REVISED: Based on 2010 PH7 rule. Updated Notes and Examples to include amyloidosis in place of myloidosis.
  5. PH7: REVISED: Based on 2010 PH8 rule. Added plasma cell leukemia to diagnosis listing. Expanded Notes and Examples.
  6. REVISED: When this module does not apply….go to Module 7 in place of Module 8 from 2010.

Module 3: PH8 - PH10

  1. REVISED listing of neoplasms that can manifest as either leukemia or lymphoma or both.
  2. PH8: REVISED: Added coding guidelines for CLL w/ or w/o SLL. Added primary site, histology guidelines and Notes and Examples.
  3. PH9: REVISED: Based on 2010 PH11. Expanded diagnosis listing. Updated Notes and Examples.
  4. PH10: REVISED: Based on 2010 PH12. Expanded diagnosis listing. Updated Notes and Examples.
  5. REVISED: When this module does not apply….go to Module 7 in place of Module 8 from 2010.

Module 4: PH11

  1. PH11: REVISED: Based on 2010 PH13. No further changes.
  2. REVISED: When this module does not apply….go to Module 7 in place of Module 8 from 2010.

Module 5: PH12 – PH15

  1. REVISED: Instructions expanded to include 9811/3 – 9897/3 and Mast Cell Neoplasms; 9742/3 and 9740/3, to module.
  2. PH12: NEW guidelines for coding mast cell sarcoma when the diagnosis includes mast cell leukemia. New Notes and Examples
  3. PH13: NEW guidelines for coding mast cell sarcoma and no previous diagnosis of mast cell leukemia.
  4. PH14: REVISED: Myeloid neoplasm changed to myeloid sarcoma when the diagnosis includes acute myeloid leukemia. Added histology codes and revised Notes and Examples.
  5. PH15: REVISED: Myeloid neoplasm changed to myeloid sarcoma and no previous diagnosis of acute myeloid leukemia. Revised Notes and Examples.
  6. REVISED: When this module does not apply….go to Module 7 in place of Module 8 from 2010.

Module 6: PH16 – PH24

  1. REVISED: Instructions expanded to include histologic titles associated with the codes.
  2. PH16: REVISED: Expanded list of inclusion histology codes. Updated Notes and Examples.
  3. PH17: REVISED: Updated rules for clarification and histology. Notes and Examples also updated.
  4. PH18: REVISED: Histology updated to include primary cutaneous follicle center cell lymphoma. Notes and Examples updated.
  5. PH19: REVISED: Histology updated to include diffuse large B-cell lymphoma.
  6. PH20: REVISED: Histology updated to include diffuse large B-cell lymphoma.
  7. PH21: REVISED: Added words synchronous/simultaneous and bone marrow to rules. Guidelines for coding histology expanded. Notes and Examples updated.
  8. PH22: REVISED: Added bone marrow to rules and to primary site. Histology rules updated to include Code to NHL with the numerically highest ICD-O-3 code.  Revised Notes and Examples.
  9. PH23: REVISED: Based on 2010 PH24. Significant revisions to coding rules, primary site and histology. New Notes and Examples.
  10. PH24: REVISED: Based on 2010 PH23. Significant revisions to coding rules, primary site and histology.
  11. REVISED: Bottom of page: Additional coding rules on coding primary site for lymphomas go to Primary Site Coding Instructions and…When this module does not apply….go to Module 7 in place of Module 8 from 2010.

Module 7: PH25 – PH37

  1. PH29: REVISED: Notes and Examples revised.
  2. PH30: REVISED: Revised wording in rules, Notes and Examples.  
  3. PH31: REVISED: Significant revisions to coding rules only.

Module 8: PH 38 – PH39

  1. NEW MODULE: Multiple Histologies Coded as a Single Primary Based on M6 and M6
  2. PH38: NEW RULE: in coding primary site, and histology for Hodgkin and non-Hodkin lymphoma in the same site.
  3. PH39: NEW RULE: in coding, primary site, and histology for two or more Non-Hodgkin lymphomas in the same site.

Module 9: PH40 – PH41

  1. NEW: Instructions for NOS and More Specific Histology: All hematopoietic and lymphoid neoplasms 9590/3 – 9992/3
  2. PH40: New Notes and Examples.
  3. PH41: New Notes and Examples.

Module 10: PH42 – PH43

  1. PH42: REVISEDNEW Notes and Examples.
  2. PH43: NEW Notes and Examples only.

Grade of Tumor Rules – Flowchart

  1. REVISED Instructions:
    • Note 1 expanded tumor rules from G1 – 9 to G1 – G11.
    • NEW: Note 3 – 6
  2. G1: REVISED: Added histology 9756/3 to histology listing.
  3. G2: REVISED: Based on 2010 G4 rules. Added 9708/3 and deleted 9714/3 to histology listing.  Added note 3 to Notes and Examples.
  4. G3: REVISED: Based on 2010 G6 rules. Added 9670/3, 9679/3, 9684/3, 9728/3, 9826/3, and 9836/3 to histology listing.
  5. G4: REVISED: Based on 2010 G9 rules. Deleted 9831/3 from histology listing. Revised Note 3 and added Note 4 in Notes and Examples.
  6. G5: NO CHANGE.
  7. G6: REVISED: Numbering only, based on 2010 G7 rules.
  8. G7: REVISED: Numbering only, based on 2010 G8 rules.
  9. G8: REVISED: Numbering only, based on 2010 G10 rules.
  10. G9: REVISED: Based on 2010 G11 rules. Numbering and formatting changes only.

Glossary - New

  • Anemia of chronic disorder/disease: NOT REPORTABLE
  • Chronic neoplasm
  • Hemolytic anemia: NOT REPORTABLE
  • In-situ Lymphoma: NOT REPORTABLE
  • Myelodysplasia: MAY BE REPORTABLE

Appendix B

Table B1:

  • REVISED: Changed to preferred name: Cutaneous mastocytosis, 9740/1 to Solitary mastocytoma of skin, 9740/1.

Table B7:

  • NEW: Adult T-cell leukemia/lymphoma 9837/3.
  • DELETED: Obsolete code B lymphoblastic leukemia/lymphoma (no code) from table.
  • DELETED: Obsolete code T lymphoblastic leukemia/lymphoma 9837/3 from table.

Table B8:

  • REVISED: Changed to preferred name: Splenic B-cell lymphoma/leukemia, unclassifiable 9591/3 to Non-Hodgkin lymphoma, NOS; splenic B-cell lymphoma/leukemia, unclassifiable 9591/3.

Table B9:

  • REVISED: Changed to preferred name: Chronic lymphoproliferative disorder of NK-cells 9831/3 to T-cell large granular lymphocytic leukemia 9831/3.
  • DELETED: Obsolete code:  Primary cutaneous CD30 positive T-cell lymphoproliferative disorders.

Table B10:

  • DELETED: Obsolete code. Nodular lymphocyte predominant Hodgkin lymphoma 9659/3.

Table B12:

  • DELETED: Obsolete code. Infectious mononucleosis-like PTLD 9971/3.

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June 2010, Version 1.6

Database Revisions

  • 9985/3: Had an ICD-10 code of D46.71. Corrected to D46.7.
  • 9986/3: Had an ICD-10 code of D46.73. Corrected to D46.7.
  • 9591/3: Non-Hodgkin lymphoma, NOS: Deleted the term "lymphosarcoma" from alternate names.
  • 9967/3: Typo in alternate name "zMyeloproliferative variant of the hyperesinophilic syncrome" changed to "Myeloproliferative variant of the hyperesinophilic syndrome.
  • 9591/3: Capitalized the word Burkitt in, "Malignant lymphoma, undifferentiated cell, non-burkitt."
  • 9596/3: Deleted the term "Composite Hodgkin and non-Hodgkin lymphoma" from alternate names since the preferred term was repeated as an alternate name.
  • 9733/3: Plasma cell leukemia: deleted "plasma cell dyscrasia" as a synonym.
  • 9872/3: Added the term "Acute myeloid leukemia with minimal differentiation" and checked the box to make Acute myeloid leukemia with minimal differentiation the preferred term.
  • 9805/3: Acute biphenic leukemia: entered site code C421 in primary site box.
  • 9814/3: Changed preferred name from (P13;22) to (p13;q22). Added q before 22.
  • 9869/3: Changed preferred name from (q21p26;2) to (q21p26.2). Changed the 26;2 to 26.2.
  • 9827/3: Adult T-cell leukemia/lymphoma Treatment: Immunotherapy listed twice, deleted one of the entries.
  • 9761/3: Waldenstrom macroglobulinemia, Abstractor Notes: Deleted last paragraph.
  • 9690/3: Follicular lymphoma, NOS Abstractor notes, first paragraph. Changed "follicular lymphoma, grade;," to "follicular lymphoma grade 2;" (added "2" and deleted comma).
  • 9659/3: Hodgkin lymphoma, nodular lymphocyte predominant, Primary Site Change from C440-C449 to C770-C779.
  • 9811/3: Precursor B-cell lymphoblastic leukemia. Abstractor Notes: Deleted, "Pre 2010 ICDO3 code are now a category of neoplasm which includes B Lymphoblastic Leukemia/Lymphoma, NO" and inserted, "For cases diagnosed 2010 and later, code pre-BALL to B-lymphoblastic leukemia/lymphoma, NOS 9811/3."

Multiple Primary Calculator

  • 9671 LPL and 9761 WM changed from "New Primary" to "Same Primary".
  • 9671 LPL and 9762 Heavy chain disease changed from "New Primary" to "Same Primary."
  • 9650/3 and 9684/3 are now "New Primary" and 9684/3 and 9650/3 are now "New Primary."
  • 9591/3 and 9650/3 are now "New Primary" and 9650/3 and 9591/3 are now "New Primary."
  • 9650/3 and 9591/3 are now "New Primary" and 951/3 and 9650/3 are now "New Primary."
  • When 9591 9724 Non-Hodgkin, NOS and EBV positive lymphoproliferative disease of childhood is entered in reverse order, 9724  9591 EBV positive lymphoproliferative disease of childhood and non-Hodgkin, NOS, it now displays Same Primary, rather than New Primary.
  • When 9591 9726 non-Hodgkin, NOS and primary cutaneous Gamma Delta T-cell lymphoma is entered in reverse order, 9726 9591 primary cutaneous Gamma Delta T-cell lymphoma and non-Hodgkin, NOS, it now displays Same Primary, rather than New Primary.
  • When 9650 9655 classical Hodgkin lymphoma and Hodgkin lymphoma, lymphocyte depletion, reticular is entered in reverse order, 9655 9650 Hodgkin lymphoma, lymphocyte depletion, reticular and classical Hodgkin lymphoma, it now displays Same Primary, rather than New Primary.
  • When 9650 9659 classical Hodgkin lymphoma and nodular lymphocyte predominant Hodgkin lymphoma is entered in reverse order, 9659 9650 nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma, it displays Same Primary, rather than New Primary.
  • When 9650/3 and 9680/3 are entered IN ANY order, the answer is now New Primary, rather than Same Primary.

Manual Revisions

Introduction

  • Pg 2: Removed from Hematopoietic Working Group list, "Wendy Scharber, RHIT, CTR, Registry Widgets, INC."
  • Pg 8: 3rd paragraph now reads as: "When the ICD-O-3 editors assign new codes for a neoplasm..."
  • Pg 11: Under "What is new and/or Different in 2010", added a comma in the first sentence after "the histology groupings." The 2nd sentence, now reads: "International Classification of Disease for Oncology."

Multiple Primary Rules

  • M3 - All Formats: Inserted new Note 1: "Do NOT use this rule for cutaneous lymphomas." Renumbered existing notes.
  • M10 - All Formats: Changed "21 days or more" to "more than 21 days."
  • M12 - All Formats: Changed Note 1 to "...when the patient has been treated for the acute disease."

PH Rules

  • PH11 - Matrix Only: Changed "Precursor B-ell lymphoblastic leukemia/lymphoma" to "Precursor cell lymphoblastic leukemia, NOS."
  • PH12 - All Formats: Bullet 2 "Blastic plasmacytoid dendritic cell neoplasm 9727/3" changed to "Blastic plasmacytoid dendritic cell neoplasm (previously called precursor cell lymphoblastic lymphoma, NOS) 9727/3."
  • PH12 - Matrix Only: Changed "Blastic plasmacytoid dendritic cell neoplasm, NOS" to "Blastic plasmacytoid dendritic cell neoplasm."
  • PH15 - Flowchart Only: Changed Histology code from "myloid" to "myeloid."
  • PH30 - Flowchart Only: Added C778 to the decision sign.

Grade Rules All Formats

  • G1: Added to numeric list in numerical order.
    • 9801/3
    • 9805/3
    • 9806/3
    • 9807/3
    • 9808/3
    • 9809/3

Glossary

  • Deleted entry for Richter's transformation and replaced with: Richter’s transformation, Richter's syndrome (RS): Transformation of B-cell chronic lymphocytic leukemia (CLL) or hairy cell leukemia (HCL) to diffuse large B-cell lymphoma.

Appendices

  • Appendix D Table 1: Changed "Myeloid and lymphoid neoplasms with PDGFRB rearrangement" to "Myeloid and lymphoid neoplasms with PDGFRA rearrangement."
  • Appendix D Table 2: Changed 9965/3 from PDGFRB to PDGFRA.
  • Appendix D Table 1: Changed "Myeloid and lymphoid neoplasms with PDGFRB arrangement" to "Myeloid and lymphoid neoplasms with PDFRB rearrangement."
  • Appendix D Table 2: Changed "Myeloid and lymphoid neoplasms with PDGFRB arrangement" to "Myeloid and lymphoid neoplasms with PDFRB rearrangement."

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April 2010, Version 1.5

Database Revisions

  1. Code 9705/3 Angioimmunoblastic lymphadenopathy with dysproteinemia: Alternate name deleted: angioimmunoblastic lymphadenopathy
  2. Code 9873/3 Acute myeloid leukemia without maturation: Alternate name typo corrected, changed from FAR M1 to FAB M1
  3. Code 9761/3 Waldenstrom macroglobulinemia: Two alternate names deleted: LPL/WM and Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia

Corrections to 2010 Hematopoietic and Lymphoid Neoplasm Case Reportability and Coding Manual

Multiple Primary Rule

  1. M3
    1. Flow Chart: Delete word “region” leaving “lymph node”
    2. Matrix first bullet: Delete word “region” leaving One lymph node”
    3. Text: Delete word “region” leaving “such as one lymph node”
  2. M4
    1. Flow Chart: Delete word “region” leaving “lymph node”
    2. Matrix first bullet: Delete word “region” leaving One lymph node”
    3. Text: Delete word “region” leaving “such as one lymph node”
  3. M10 flowchart, matrix, and text
    1. Note 2 deleted
    2. Note 3 renumbered to read “Note 2”
  4. M10 Matrix format did not display. Display error corrected.

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March 2010, Version 1.4

Database Revisions

  1. Angiocentric immunoproliferative lesion now appears under only one code number
  2. Code 9765/1 now displays the histology term MGUS
  3. Code 9872/3 now displays the histology term Acute myeloblastic leukemia
  4. Code 9733/3 Plasma cell leukemia abstractor note: correction of typographical error, last sentence said “See 0732/3 for more information” Code number corrected to read “9732/3
  5. Code 9837/3 preferred name changed from Adult T-cell leukemia/lymphoma to T lymphoblastic leukemia/lymphoma.
  6. Code 9837/3 T lymphoblastic leukemia/lymphoma: abstractor note text modified

Corrections to 2010 Hematopoietic & Lymphoid Neoplasm Case Reportability and Coding Manual

  1. New flowcharts with errors corrected
  2. Rule clarifications, flowchart, matrix, and text
    1. Multiple Primary M6: Deleted words “in the same histologic grouping as defined in Appendix D Histology Lineages”  Replaced with “when the Hematopoietic DB Multiple Primary Calculator confirms that the NOS and more specific histology are the same primary”
    2. Primary Site and Histology PH10: Delete words “AND peripheral blood and flow cytometry are negative or unknown”
  3. Grade G9 Note 3: Changed link from Table B8 to Table B9
  4. Appendix B corrections
    1. Table B5 additions
      1. 9891/3  Acute monoblastic and monocytic leukemia
      2. 9865/3 Acute myeloid leukemia with t(6;9)(p23;q34); DEK-NUP214
    2. Table B9 addition: 9761/3 Waldenstrom macroglobulinemia
  5. Appendix E, Tables E1 and E2: Code for myeloproliferative disease, NOS changed from 9975/1 to 9975/3

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