The SEED project performs curation of genomic data which is then used for extraction of protein families (FIGfams).
FIGfams 01 Amino Acids and Derivatives 02 Alanine, serine, and glycine Alanine_biosynthesis Alanine racemase (EC 5.1.1.1) Alanine racemase, biosynthetic (EC 5.1.1.1) Alanine racemase, catabolic (EC 5.1.1.1) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Cysteine desulfurase (EC 2.8.1.7) Cysteine desulfurase (EC 2.8.1.7), IscS subfamily Cysteine desulfurase (EC 2.8.1.7), NifS subfamily Cysteine desulfurase (EC 2.8.1.7), SufS subfamily Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA Glutamate-pyruvate aminotransferase (EC 2.6.1.2) HTH-type transcriptional regulator IlvY Valine--pyruvate aminotransferase (EC 2.6.1.66) Valine--pyruvate aminotransferase (EC 2.6.1.66) Glycine_Biosynthesis 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) Glycine riboswitch L-threonine 3-dehydrogenase (EC 1.1.1.103) Low-specificity L-threonine aldolase (EC 4.1.2.5) Serine hydroxymethyltransferase (EC 2.1.2.1) Glycine_and_Serine_Utilization 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) Cystathionine beta-synthase (EC 4.2.1.22) Cystathionine gamma-lyase (EC 4.4.1.1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) D-serine dehydratase (EC 4.3.1.18) D-serine dehydratase transcriptional activator D-serine permease DsdX D-serine/D-alanine/glycine transporter Glycerate kinase (EC 2.7.1.31) Glycine cleavage system H protein Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2) L-serine dehydratase (EC 4.3.1.17) L-serine dehydratase 1 (EC 4.3.1.17) L-serine dehydratase, alpha subunit (EC 4.3.1.17) L-serine dehydratase, beta subunit (EC 4.3.1.17) Monoamine oxidase (1.4.3.4) Phosphoserine aminotransferase (EC 2.6.1.52) Phosphoserine phosphatase (EC 3.1.3.3) Serine hydroxymethyltransferase (EC 2.1.2.1) Serine transporter Seryl-tRNA synthetase (EC 6.1.1.11) Threonine dehydratase, catabolic (EC 4.3.1.19) Glycine_cleavage_system Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Glycine cleavage system H protein Glycine cleavage system transcriptional activator GcvA Glycine cleavage system transcriptional antiactivator GcvR Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2) Glycine riboswitch Lipoate-protein ligase A type 2 Similar to Glycine cleavage system H protein Sodium/glycine symporter GlyP Serine_Biosynthesis D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) Phosphoserine aminotransferase (EC 2.6.1.52) Phosphoserine aminotransferase, putative (EC 2.6.1.52) Phosphoserine phosphatase (EC 3.1.3.3) Phosphoserine phosphatase (EC 3.1.3.3) Serine hydroxymethyltransferase (EC 2.1.2.1) Serine hydroxymethyltransferase 1 (EC 2.1.2.1) 02 Arginine; urea cycle, polyamines Anaerobic_Oxidative_Degradation_of_L-Ornithine 2,4-diaminopentanoate dehydrogenase (EC 1.4.1.12) 2-amino-4-ketopentanoate thiolase, alpha subunit 2-amino-4-ketopentanoate thiolase, beta subunit D-Ornithine 4,5-aminomutase E subunit (EC 5.4.3.5) D-Ornithine 4,5-aminomutase S subunit (EC 5.4.3.5) Ornithine racemase (EC 5.1.1.12) Probable reactivating factor for D-ornithine aminomutase Arginine_Biosynthesis_extended Acetylglutamate kinase (EC 2.7.2.8) Acetylornithine aminotransferase (EC 2.6.1.11) Acetylornithine aminotransferase 1 (EC 2.6.1.11) Acetylornithine aminotransferase 2 (EC 2.6.1.11) Acetylornithine deacetylase (EC 3.5.1.16) Arginine pathway regulatory protein ArgR, repressor of arg regulon Argininosuccinate lyase (EC 4.3.2.1) Argininosuccinate synthase (EC 6.3.4.5) Glutamate N-acetyltransferase (EC 2.3.1.35) N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) N-acetylglutamate synthase (EC 2.3.1.1) N-acetylornithine carbamoyltransferase (EC 2.1.3.9) N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18) Ornithine carbamoyltransferase (EC 2.1.3.3) Predicted amino-acid acetyltransferase (EC 2.3.1.1) complementing ArgA function in Arginine Biosynthesis pathway Predicted arginine uptake transporter Arginine_Deiminase_Pathway Arginine deiminase (EC 3.5.3.6) Arginine pathway regulatory protein ArgR, repressor of arg regulon Arginine/ornithine antiporter ArcD Carbamate kinase (EC 2.7.2.2) Ornithine carbamoyltransferase (EC 2.1.3.3) Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family Arginine_and_Ornithine_Degradation Agmatinase (EC 3.5.3.11) Agmatine deiminase (EC 3.5.3.12) Arginase (EC 3.5.3.1) Arginine ABC transporter, ATP-binding protein ArtP Arginine ABC transporter, periplasmic arginine-binding protein ArtI Arginine ABC transporter, periplasmic arginine-binding protein ArtJ Arginine ABC transporter, permease protein ArtM Arginine ABC transporter, permease protein ArtQ Arginine N-succinyltransferase (EC 2.3.1.109) Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) Arginine N-succinyltransferase, beta subunit (EC 2.3.1.109) Arginine decarboxylase (EC 4.1.1.19) Arginine decarboxylase, catabolic (EC 4.1.1.19) Arginine deiminase (EC 3.5.3.6) Arginine pathway regulatory protein ArgR, repressor of arg regulon Arginine permease RocE Arginine utilization protein RocB Arginine utilization regulatory protein RocR Arginine/agmatine antiporter Arginine/ornithine ABC transporter, ATP-binding protein AotP Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein Arginine/ornithine ABC transporter, permease protein AotM Arginine/ornithine ABC transporter, permease protein AotQ Arginine/ornithine antiporter ArcD Biosynthetic arginine decarboxylase (EC 4.1.1.19) Carbamate kinase (EC 2.7.2.2) Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) Histidine ABC transporter, histidine-binding periplasmic protein precursor HisJ (TC 3.A.1.3.1) Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1) Histidine ABC transporter, permease protein HisQ (TC 3.A.1.3.1) Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) N-carbamoylputrescine amidase (3.5.1.53) NADP-specific glutamate dehydrogenase (EC 1.4.1.4) Ornithine aminotransferase (EC 2.6.1.13) Ornithine carbamoyltransferase (EC 2.1.3.3) Ornithine cyclodeaminase (EC 4.3.1.12) Ornithine decarboxylase (EC 4.1.1.17) Putrescine aminotransferase (EC 2.6.1.82) Succinylarginine dihydrolase (EC 3.5.3.23) Succinylglutamate desuccinylase (EC 3.5.1.96) Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) Succinylornithine transaminase (EC 2.6.1.81) Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family Transcriptional regulator of catabolic arginine decarboxylase (adiA) Cyanophycin_Metabolism Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) Cyanophycin synthase (EC 6.3.2.29)(EC 6.3.2.30) Cyanophycin synthase II Cyanophycinase (EC 3.4.15.6) Cyanophycinase (EC 3.4.15.6) dimer Cyanophycinase 2 (EC 3.4.15.6) Polyamine_Metabolism 4-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) Agmatinase (EC 3.5.3.11) Agmatine deiminase (EC 3.5.3.12) Agmatine/putrescine antiporter, associated with agmatine catabolism Arginine decarboxylase (EC 4.1.1.19) Arginine decarboxylase, catabolic (EC 4.1.1.19) Arginine/agmatine antiporter Arginine/ornithine antiporter Arginine/ornithine antiporter ArcD Biosynthetic arginine decarboxylase (EC 4.1.1.19) Carbamate kinase (EC 2.7.2.2) Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) DNA-binding response regulator, LuxR family, near polyamine transporter N-carbamoylputrescine amidase (3.5.1.53) Ornithine decarboxylase (EC 4.1.1.17) Predicted chaperone lipoprotein YacC, potentially involved in protein secretion Predicted polyamine sensor NspS, involved in biofilm formation Probable spermidine/putrescine substrate binding protein in Mollicutes Probable two-component sensor, near polyamine transporter Putative GntR-family regulatory protein and aminotransferase near polyamine transporter Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) Putrescine carbamoyltransferase (EC 2.1.3.6) Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) Putrescine transport system permease protein PotH (TC 3.A.1.11.2) Putrescine transport system permease protein PotI (TC 3.A.1.11.2) Putrescine-ornithine antiporter Putrescine/proton symporter, putrescine/ornithine antiporter PotE S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), eukaryotic S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1B Spermidine N1-acetyltransferase (EC 2.3.1.57) Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) Spermidine synthase (EC 2.5.1.16) Transcriptional regulator of catabolic arginine decarboxylase (adiA) Transcriptional regulator, MerR family, near polyamine transporter Transcriptional regulator, TetR family, associated with agmatine catabolism Transcriptional regulator, luxR family, associated with agmatine catabolism Putrescine_utilization_pathways 4-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) Gamma-glutamyl-GABA hydrolase (EC 3.5.1.94) Gamma-glutamyl-aminobutyraldehyde dehydrogenase (EC 1.2.1.-) Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) Glycine/D-amino acid oxidase (deaminating) in putrescine utilization cluster Monoamine/putrescine oxidase (EC 1.4.3.10) Putative oxidoreductase in putrescine utilization cluster Putative symporter in putrescine utilization cluster Putrescine aminotransferase (EC 2.6.1.82) Putrescine importer Putrescine utilization regulator Similar to gamma-glutamyl-putrescine oxidase Uncharacterized protein in putrescine utilization cluster Urea_decomposition Allophanate hydrolase (EC 3.5.1.54) Eukaryotic-type low-affinity urea transporter HupE-UreJ family metal transporter Nickel transporter UreH Partial urea carboxylase (EC 6.3.4.6) Partial urea carboxylase 2 (EC 6.3.4.6) Urea ABC transporter, ATPase protein UrtD Urea ABC transporter, ATPase protein UrtE Urea ABC transporter, permease protein UrtB Urea ABC transporter, permease protein UrtC Urea ABC transporter, urea binding protein Urea carboxylase (EC 6.3.4.6) Urea carboxylase-related ABC transporter, ATPase protein Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein Urea carboxylase-related ABC transporter, permease protein Urea carboxylase-related amino acid permease Urea carboxylase-related aminomethyltransferase (EC 2.1.2.10) Urea channel UreI Urease accessory protein UreD Urease accessory protein UreE Urease accessory protein UreF Urease accessory protein UreG Urease alpha subunit (EC 3.5.1.5) Urease beta subunit (EC 3.5.1.5) Urease gamma subunit (EC 3.5.1.5) 02 Aromatic amino acids and derivatives Aromatic_amino_acid_degradation 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.-) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) 3,4-dihydroxyphenylacetate 2,3-dioxygenase (EC 1.13.11.15) 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) 5-carboxymethyl-2-hydroxymuconate delta-isomerase (EC 5.3.3.10) 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.2.1.60) 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. Anthranilate dioxygenase large subunit Anthranilate dioxygenase reductase Anthranilate dioxygenase small subunit Aromatic amino acid transport protein AroP Aromatic ring-opening dioxygenase Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) Homoprotocatechuate degradative operon repressor Indoleacetamide hydrolase (EC 3.5.1.-) Kynurenine formamidase, bacterial (EC 3.5.1.9) Phenylalanine hydroxylase transcriptional activator PhhR Phenylalanine-4-hydroxylase (EC 1.14.16.1) Phenylalanine-specific permease Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase Probable 5-carboxymethyl-2-hydroxymuconate delta isomerase Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Putative 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase oxidoreductase protein (EC 1.2.1.60) Putative fumarylacetoacetate (FAA) hydrolase Tryptophan 2,3-dioxygenase (EC 1.13.11.11) Tryptophan 2-monooxygenase (EC 1.13.12.3) Tryptophanase (EC 4.1.99.1) Aromatic_amino_acid_interconversions_with_aryl_acids Amino acid-binding ACT Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Indolepyruvate oxidoreductase subunit IorA (EC 1.2.7.8) Indolepyruvate oxidoreductase subunit IorA-like (EC 1.2.7.8) Indolepyruvate oxidoreductase subunit IorB (EC 1.2.7.8) Indolepyruvate oxidoreductase subunit IorB II (EC 1.2.7.8) Phenylacetate-coenzyme A ligase (EC 6.2.1.30) Bacilysin_biosynthesis Alanine-anticapsin ligase BacD Bacilysin biosynthesis oxidoreductase BacC Bacilysin biosynthesis protein BacA Bacilysin biosynthesis protein BacB Bacilysin exporter protein BacE Chorismate:_Intermediate_for_synthesis_of_PAPA_antibiotics,_PABA,_anthranilate,_3-hydroxyanthranilate_and_more. 2-Amino-2-deoxy-isochorismate hydrolase (EC 3.-.-.-) 2-Amino-2-deoxy-isochorismate synthase (EC 4.1.3.-) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase II PhzC (EC 2.5.1.54) 4-amino, 4-deoxychorismate mutase (EC 5.4.99.-) 4-amino, 4-deoxyprephenate dehydrogenase (EC 1.3.1.-) 4-amino-4-deoxychorismate synthase, amidotransferase component , aminase component (EC 2.6.1.-) Aminodeoxychorismate lyase (EC 4.1.3.38) Anthranilate synthase, amidotransferase component (EC 4.1.3.27) Anthranilate synthase, aminase component (EC 4.1.3.27) Isochorismatase (EC 3.3.2.1) Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis Isochorismate pyruvate-lyase (EC 4.-.-.-) Isochorismate pyruvate-lyase of siderophore biosynthesis Isochorismate synthase (EC 5.4.4.2) Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis Para-amino-L-phenylalanine methyltransferase (EC 2.1.1.-) Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) Chorismate_Synthesis 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.5.1.-) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha (EC 2.5.1.54) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I beta (EC 2.5.1.54) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase II (EC 2.5.1.54) 3,7-dideoxy-D-threo-hepto-2, 6-diulosonate synthase (EC 4.2.3.-) 3-dehydroquinate dehydratase I (EC 4.2.1.10) 3-dehydroquinate dehydratase II (EC 4.2.1.10) 3-dehydroquinate synthase (EC 4.2.3.4) 4-amino, 4-deoxychorismate mutase (EC 5.4.99.-) 4-amino, 4-deoxyprephenate dehydrogenase (EC 1.3.1.-) 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) Arogenate dehydrogenase (EC 1.3.1.43) Chorismate mutase I (EC 5.4.99.5) Chorismate mutase II (EC 5.4.99.5) Chorismate synthase (EC 4.2.3.5) Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) Periplasmic chorismate mutase I precursor (EC 5.4.99.5) Prephenate and/or arogenate dehydrogenase (unknown specificity) (EC 1.3.1.12)(EC 1.3.1.43) Prephenate dehydratase (EC 4.2.1.51) Prephenate dehydrogenase (EC 1.3.1.12) Quinate/shikimate 5-dehydrogenase I delta (EC 1.1.1.25) Quinate/shikimate dehydrogenase [Pyrroloquinoline-quinone] (EC 1.1.99.25) Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) Shikimate 5-dehydrogenase I gamma (EC 1.1.1.25) Shikimate kinase I (EC 2.7.1.71) Shikimate kinase II (EC 2.7.1.71) Shikimate kinase III (EC 2.7.1.71) Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282) Common_Pathway_For_Synthesis_of_Aromatic_Compounds_(DAHP_synthase_to_chorismate) 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.5.1.-) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha (EC 2.5.1.54) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I beta (EC 2.5.1.54) 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase II (EC 2.5.1.54) 3,7-dideoxy-D-threo-hepto-2, 6-diulosonate synthase (EC 4.2.3.-) 3-dehydroquinate dehydratase I (EC 4.2.1.10) 3-dehydroquinate dehydratase II (EC 4.2.1.10) 3-dehydroquinate synthase (EC 4.2.3.4) 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) Chorismate synthase (EC 4.2.3.5) Quinate/shikimate 5-dehydrogenase I delta (EC 1.1.1.25) Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) Shikimate 5-dehydrogenase I gamma (EC 1.1.1.25) Shikimate kinase I (EC 2.7.1.71) Shikimate kinase II (EC 2.7.1.71) Shikimate kinase III (EC 2.7.1.71) Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282) Transcriptional repressor protein TrpR Transcriptional repressor protein TyrR Indole-pyruvate_oxidoreductase_complex Indolepyruvate oxidoreductase subunit IorA (EC 1.2.7.8) Indolepyruvate oxidoreductase subunit IorB (EC 1.2.7.8) Phenylalanine_and_Tyrosine_Branches_from_Chorismate Arogenate dehydratase (EC 4.2.1.91) Arogenate dehydrogenase (EC 1.3.1.43) Aromatic amino acid aminotransferase gamma (EC 2.6.1.57) Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) Chorismate mutase (EC 5.4.99.5) Chorismate mutase I (EC 5.4.99.5) Chorismate mutase II (EC 5.4.99.5) Cyclohexadienyl dehydratase (EC 4.2.1.51)(EC 4.2.1.91) Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) Periplasmic aromatic amino acid aminotransferase beta precursor (EC 2.6.1.57) Periplasmic chorismate mutase I precursor (EC 5.4.99.5) Prephenate and/or arogenate dehydrogenase (unknown specificity) (EC 1.3.1.12)(EC 1.3.1.43) Prephenate dehydratase (EC 4.2.1.51) Prephenate dehydrogenase (EC 1.3.1.12) Transcriptional repressor protein TyrR Tryptophan_catabolism 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) 2-aminomuconate deaminase (EC 3.5.99.5) 2-aminomuconate semialdehyde dehydrogenase (EC 1.2.1.32) 2-keto-4-pentenoate hydratase (EC 4.2.1.-) 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) 4-oxalocrotonate decarboxylase (EC 4.1.1.77) Acetaldehyde dehydrogenase (EC 1.2.1.10) Kynureninase (EC 3.7.1.3) Kynurenine 3-monooxygenase (EC 1.14.13.9) Kynurenine formamidase (EC 3.5.1.9) Kynurenine formamidase, bacterial (EC 3.5.1.9) Tryptophan 2,3-dioxygenase (EC 1.13.11.11) Tryptophan_synthesis Acting phosphoribosylanthranilate isomerase (EC 5.3.1.24) Anthranilate phosphoribosyltransferase (EC 2.4.2.18) Anthranilate synthase, amidotransferase component (EC 4.1.3.27) Anthranilate synthase, aminase component (EC 4.1.3.27) Indole-3-glycerol phosphate synthase (EC 4.1.1.48) Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Phosphoribosylanthranilate isomerase (EC 5.3.1.24) Tryptophan synthase alpha chain (EC 4.2.1.20) Tryptophan synthase beta chain (EC 4.2.1.20) 02 Branched-chain amino acids Branched-Chain_Amino_Acid_Biosynthesis (R)-citramalate synthase (EC 2.3.1.182) 2-isopropylmalate synthase (EC 2.3.3.13) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) Acetolactate synthase large subunit (EC 2.2.1.6) Acetolactate synthase small subunit (EC 2.2.1.6) Acetolactate synthase small subunit (EC 2.2.1.6), Xanthomonadales type Acetolactate synthase small subunit (EC 2.2.1.6), predicted Acetolactate synthase small subunit (EC 2.2.1.6), predicted, Archaeal type Acetolactate synthase small subunit (EC 2.2.1.6), predicted, Archaeal type 2 Branched-chain amino acid aminotransferase (EC 2.6.1.42) Dihydroxy-acid dehydratase (EC 4.2.1.9) Ketol-acid reductoisomerase (EC 1.1.1.86) Leucine dehydrogenase (EC 1.4.1.9) Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system Threonine dehydratase (EC 4.3.1.19) Threonine dehydratase biosynthetic (EC 4.3.1.19) Threonine dehydratase, catabolic (EC 4.3.1.19) Valine--pyruvate aminotransferase (EC 2.6.1.66) Branched_chain_amino_acid_degradation_regulons 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) Acetoacetyl-CoA synthetase (EC 6.2.1.16) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Electron transfer flavoprotein, alpha subunit Electron transfer flavoprotein, beta subunit Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1) Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) Isovaleryl-CoA dehydrogenase (EC 1.3.99.10) Leucine dehydrogenase (EC 1.4.1.9) Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) Methylglutaconyl-CoA hydratase (EC 4.2.1.18) Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) Predicted transcriptional regulator LiuQ of leucine degradation pathway, TetR family Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) Transcriptional regulator BkdR of isoleucine and valine catabolism operon HMG_CoA_Synthesis Acetoacetyl-CoA synthetase (EC 6.2.1.16) Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16) Biotin carboxyl carrier protein of methylcrotonyl-CoA carboxylase Biotin carboxylase of methylcrotonyl-CoA carboxylase (EC 6.3.4.14) Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) Isovaleryl-CoA dehydrogenase (EC 1.3.99.10) Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) Methylglutaconyl-CoA hydratase (EC 4.2.1.18) Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family Isoleucine_degradation 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Butyrate kinase (EC 2.7.2.7) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) Enoyl-CoA hydratase (EC 4.2.1.17) Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) Predicted transcriptional regulator of leucine degradation pathway, MerR family Probable acyl-CoA dehydrogenase (EC 1.3.99.3) Transcriptional regulator BkdR of isoleucine and valine catabolism operon phosphotransbutyrylase (EC 2.3.1.19) Ketoisovalerate_oxidoreductase Acetyl-coenzyme A synthetase (EC 6.2.1.1) Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) Ketoisovalerate oxidoreductase subunit (EC 1.2.7.7) Ketoisovalerate oxidoreductase subunit VorA (EC 1.2.7.7) Ketoisovalerate oxidoreductase subunit VorB (EC 1.2.7.7) Ketoisovalerate oxidoreductase subunit VorC (EC 1.2.7.7) Ketoisovalerate oxidoreductase subunit VorD (EC 1.2.7.7) Ketoisovalerate oxidoreductase subunit VorG (EC 1.2.7.7) Pyruvate:ferredoxin oxidoreductase, gamma subunit (EC 1.2.7.1) Transcriptional regulator, Hth-3 family conserved protein associated with acetyl-CoA C-acyltransferase nonspecific lipid-transfer protein (acethyl CoA synthetase) Leucine_Biosynthesis 2-isopropylmalate synthase (EC 2.3.3.13) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Leu operon leader peptide Probable transcriptional activator for leuABCD operon Leucine_Degradation_and_HMG-CoA_Metabolism Acetoacetyl-CoA synthetase (EC 6.2.1.16) Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16) Biotin carboxyl carrier protein of methylcrotonyl-CoA carboxylase Biotin carboxylase of methylcrotonyl-CoA carboxylase (EC 6.3.4.14) Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34) Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) Isovaleryl-CoA dehydrogenase (EC 1.3.99.10) Leucine dehydrogenase (EC 1.4.1.9) Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) Methylglutaconyl-CoA hydratase (EC 4.2.1.18) Predicted transcriptional regulator of leucine degradation pathway, MerR family Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) Valine_degradation 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Branched-chain amino acid aminotransferase (EC 2.6.1.42) Butyrate kinase (EC 2.7.2.7) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) Enoyl-CoA hydratase (EC 4.2.1.17) Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) Predicted transcriptional regulator of leucine degradation pathway, MerR family Probable acyl-CoA dehydrogenase (EC 1.3.99.3) Transcriptional regulator BkdR of isoleucine and valine catabolism operon phosphotransbutyrylase (EC 2.3.1.19) 02 Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Glutamate_dehydrogenases NAD-specific glutamate dehydrogenase (EC 1.4.1.2) NAD-specific glutamate dehydrogenase (EC 1.4.1.2), eukaryotic type NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form NADP-specific glutamate dehydrogenase (EC 1.4.1.4) Glutamine,_Glutamate,_Aspartate_and_Asparagine_Biosynthesis Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) AsnB Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) AsnH Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) YisO Aspartate aminotransferase (EC 2.6.1.1) Aspartate ammonia-lyase (EC 4.3.1.1) Aspartate racemase (EC 5.1.1.13) Aspartate--ammonia ligase (EC 6.3.1.1) Ferredoxin-dependent glutamate synthase (EC 1.4.7.1) Glutamate racemase (EC 5.1.1.3) Glutamate synthase [NADPH] large chain (EC 1.4.1.13) Glutamate synthase [NADPH] putative GlxC chain (EC 1.4.1.13) Glutamate synthase [NADPH] small chain (EC 1.4.1.13) Glutaminase (EC 3.5.1.2) Glutamine amidotransferase protein GlxB (EC 2.4.2.-) Glutamine synthetase (EC 6.3.1.2) Glutamine synthetase family protein in hypothetical Actinobacterial gene cluster Glutamine synthetase type I (EC 6.3.1.2) Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) Glutamine synthetase type III, GlnN (EC 6.3.1.2) Glutamine synthetase, clostridia type (EC 6.3.1.2) L-asparaginase (EC 3.5.1.1) Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system NAD-specific glutamate dehydrogenase (EC 1.4.1.2) NAD-specific glutamate dehydrogenase (EC 1.4.1.2), eukaryotic type NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form NADP-specific glutamate dehydrogenase (EC 1.4.1.4) Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) glutamine synthetase family protein Glutamine_synthetases Glutamine synthetase type I (EC 6.3.1.2) Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) Glutamine synthetase type III, GlnN (EC 6.3.1.2) Glutamine synthetase, clostridia type (EC 6.3.1.2) Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) Poly-gamma-glutamate_biosynthesis Capsule synthesis positive regulator AcpA Capsule synthesis positive regulator AcpB Gamma-DL-glutamyl hydrolase PgsS (EC 3.4.19.-), catalyzes PGA release Gamma-glutamyltranspeptidase (EC 2.3.2.2) Gamma-glutamyltranspeptidase PgsD/CapD (EC 2.3.2.2), catalyses PGA anchorage to peptidoglycan Glutamate racemase (EC 5.1.1.3) Hypothetical protein in predicted poly-gamma-glutamate synthase operon Major facilitator superfamily (MFS) transporter in predicted poly-gamma-glutamate synthase operon Poly-gamma-glutamate synthase subunit PgsA/CapA (EC 6.3.2.-) Poly-gamma-glutamate synthase subunit PgsB/CapB (EC 6.3.2.-) Poly-gamma-glutamate synthase subunit PgsC/CapC (EC 6.3.2.-) Poly-gamma-glutamate synthase subunit PgsE/CapE (EC 6.3.2.-) Putative transition state regulator Abh Transition state regulatory protein AbrB transcriptional activator AtxA, (pXO1-119) 02 Histidine Metabolism Histidine_Biosynthesis ATP phosphoribosyltransferase (EC 2.4.2.17) ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) ATP phosphoribosyltransferase regulatory subunit, divergent variant (EC 2.4.2.17) Histidinol dehydrogenase (EC 1.1.1.23) Histidinol-phosphatase (EC 3.1.3.15) Histidinol-phosphatase [alternative form] (EC 3.1.3.15) Histidinol-phosphate aminotransferase (EC 2.6.1.9) Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) Histidine_Degradation Conserved hypothetical protein (perhaps related to histidine degradation) Formiminoglutamase (EC 3.5.3.8) Formiminoglutamic iminohydrolase (EC 3.5.3.13) Glutamate formiminotransferase (EC 2.1.2.5) Histidine ammonia-lyase (EC 4.3.1.3) Histidine transport protein (permease) Histidine utilization repressor Hut operon positive regulatory protein Imidazolonepropionase (EC 3.5.2.7) N-formylglutamate deformylase (EC 3.5.1.68) N-formylglutamate deformylase (EC 3.5.1.68) [alternative form] Urocanate hydratase (EC 4.2.1.49) 02 Lysine, threonine, methionine, and cysteine Cysteine_Biosynthesis Adenylylsulfate kinase (EC 2.7.1.25) Cys regulon transcriptional activator CysB Cystathionine beta-synthase (EC 4.2.1.22) Cystathionine gamma-lyase (EC 4.4.1.1) Cysteine synthase (EC 2.5.1.47) Cysteine synthase A (EC 2.5.1.47) Cysteine synthase B (EC 2.5.1.47) Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) Serine acetyltransferase (EC 2.3.1.30) Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) Sulfate and thiosulfate binding protein CysP Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) Sulfate permease Sulfate permease, Trk-type Sulfate transport system permease protein CysT Sulfate transport system permease protein CysW Sulfate transporter, CysZ-type Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2) Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) Lysine_Biosynthesis_DAP_Pathway 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Aspartokinase (EC 2.7.2.4) Diaminopimelate decarboxylase (EC 4.1.1.20) Diaminopimelate epimerase (EC 5.1.1.7) Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7) Dihydrodipicolinate reductase (EC 1.3.1.26) Dihydrodipicolinate synthase (EC 4.2.1.52) L,L-diaminopimelate aminotransferase (EC 2.6.1.83) LL-diaminopimelate aminotransferase, predicted alternative Meso-diaminopimelate D-dehydrogenase (EC 1.4.1.16) N-acetyl-L,L-diaminopimelate aminotransferase (EC 2.6.1.-) N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47) N-succinyl-L,L-diaminopimelate aminotransferase (EC 2.6.1.17) N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17) N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18) Lysine_biosynthesis_AAA_pathway_2 Acetylaminoadipate kinase (EC 2.7.2.-) Alpha-aminoadipate aminotransferase (EC 2.6.1.39) Homoaconitase large subunit (EC 4.2.1.36) Homoaconitase small subunit (EC 4.2.1.36) Homocitrate synthase (EC 2.3.3.14) Homoisocitrate dehydrogenase (EC 1.1.1.87) Lysine biosynthesis protein LysX N-acetyl-gamma-aminoadipyl-phosphate reductase (EC 1.2.1.-) N-acetyl-lysine aminotransferase (EC 2.6.1.-) N-acetyl-lysine deacetylase (EC 3.5.1.-) Lysine_degradation 5-aminopentanamidase (EC 3.5.1.30) 5-aminovalerate aminotransferase (EC 2.6.1.48) Beta-lysine acetyltransferase (EC 2.3.1.-) Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC 1.2.1.31) L-beta-lysine 5,6-aminomutase alpha subunit (EC 5.4.3.3) L-beta-lysine 5,6-aminomutase beta subunit (EC 5.4.3.3) L-lysine aminomutase regulator L-lysine permease L-pipecolate dehydrogenase (EC 1.5.99.3) L-pipecolate oxidase (1.5.3.7) Lysine 2,3-aminomutase (EC 5.4.3.2) Lysine 2-monooxygenase (EC 1.13.12.2) Lysine decarboxylase (EC 4.1.1.18) Lysine decarboxylase 2, constitutive (EC 4.1.1.18) Lysine decarboxylase, inducible (EC 4.1.1.18) Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR) Lysine/cadaverine antiporter membrane protein CadB Outer membrane porin, OprD family Saccharopine dehydrogenase (EC 1.5.1.9) Saccharopine dehydrogenase [NAD+, L-lysine-forming] (EC 1.5.1.7) Saccharopine dehydrogenase [NADP , L-glutamate-forming] (EC 1.5.1.10) Transcriptional activator of cad operon Lysine_fermentation 3,5-diaminobexanoate dehydrogenase (EC 1.4.1.11) 3-aminobutyrl-CoA ammonia lyase (EC 4.3.1.14) 3-keto-5-aminohexanoate cleavage enzyme Acetate kinase (EC 2.7.2.1) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Butyrate-acetoacetate CoA-transferase subunit A (EC 2.8.3.9) Butyrate-acetoacetate CoA-transferase subunit B (EC 2.8.3.9) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Electron transfer flavoprotein, alpha subunit Electron transfer flavoprotein, beta subunit L-beta-lysine 5,6-aminomutase alpha subunit (EC 5.4.3.3) L-beta-lysine 5,6-aminomutase beta subunit (EC 5.4.3.3) Lysine 2,3-aminomutase (EC 5.4.3.2) Methionine_Biosynthesis 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) Adenosylhomocysteinase (EC 3.3.1.1) Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) Cystathionine beta-lyase (EC 4.4.1.8) Cystathionine beta-lyase, type II (EC 4.4.1.8) Cystathionine beta-synthase (EC 4.2.1.22) Cystathionine gamma-lyase (EC 4.4.1.1) Cystathionine gamma-synthase (EC 2.5.1.48) Cysteine synthase (EC 2.5.1.47) Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter Homocysteine S-methyltransferase (EC 2.1.1.10) Homoserine O-acetyltransferase (EC 2.3.1.31) Homoserine O-succinyltransferase (EC 2.3.1.46) Homoserine dehydrogenase (EC 1.1.1.3) Homoserine kinase (EC 2.7.1.39) Methionine ABC transporter ATP-binding protein Methionine ABC transporter permease protein Methionine ABC transporter substrate-binding protein Methionine repressor MetJ Methionine synthase activation domain (EC 2.1.1.13) Methionine transporter MetT O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) Predicted regulator of methionine metabolism, ArsR family S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) S-adenosylmethionine synthetase (EC 2.5.1.6) S-ribosylhomocysteine lyase (EC 4.4.1.21) SAM-dependent methlytransferase UbiG SAM-dependent methlytransferase YrrT Serine acetyltransferase (EC 2.3.1.30) Substrate-specific component MtsA of methionine-regulated ECF transporter Transcriptional activator MetR Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter Methionine_Degradation 2-Oxobutyrate dehydrogenase E1 (EC:1.2.4.1) 2-Oxobutyrate oxidase, putative Adenosylhomocysteinase (EC 3.3.1.1) Cystathionine beta-synthase (EC 4.2.1.22) Cystathionine gamma-lyase (EC 4.4.1.1) Methionine ABC transporter ATP-binding protein Methionine ABC transporter permease protein Methionine ABC transporter substrate-binding protein Methionine gamma-lyase (EC 4.4.1.11) Methionine transporter MetT Pyruvate dehydrogenase E1 component (EC 1.2.4.1) Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) S-adenosylmethionine synthetase (EC 2.5.1.6) S-ribosylhomocysteine lyase (EC 4.4.1.21) Methionine_Salvage 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77) 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase related protein 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) 5'-methylthioadenosine phosphorylase (EC 2.4.2.28) 5-methylthioribose kinase (EC 2.7.1.100) Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase Methionine aminotransferase, PLP-dependent Methylthioribose-1-phosphate isomerase (EC 5.3.1.23) Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109) Methylthioribulose-1-phosphate dehydratase related protein Threonine_anaerobic_catabolism_gene_cluster 2-ketobutyrate formate-lyase (EC 2.3.1.-) Acetate kinase (EC 2.7.2.1) Hypothetical protein TdcF in cluster with anaerobic degradation of L-threonine to propionate L-threonine transporter, anaerobically inducible Phosphate acetyltransferase (EC 2.3.1.8) Predicted L-serine dehydratase (EC 4.3.1.17) TdcG Propionate kinase (EC 2.7.2.15) Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) Serine transporter Threonine catabolic operon transcriptional activator TdcA Threonine catabolic operon transcriptional activator TdcR Threonine dehydratase, catabolic (EC 4.3.1.19) Threonine_and_Homoserine_Biosynthesis Aspartate aminotransferase (EC 2.6.1.1) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Aspartokinase (EC 2.7.2.4) Homoserine dehydrogenase (EC 1.1.1.3) Homoserine kinase (EC 2.7.1.39) Predicted functional analog of homoserine kinase (EC 2.7.1.-) Threonine synthase (EC 4.2.3.1) Threonine_degradation FIG003492: Threonine dehydrogenase and related Zn-dependent dehydrogenases L-allo-threonine aldolase L-allo-threonine aldolase (EC 2.1.2.1) L-threonine 3-dehydrogenase (EC 1.1.1.103) L-threonine transporter, anaerobically inducible Low-specificity L-threonine aldolase (EC 4.1.2.5) Monoamine oxidase (1.4.3.4) Threonine catabolic operon transcriptional activator TdcR Threonine dehydratase (EC 4.3.1.19) Threonine dehydratase, catabolic (EC 4.3.1.19) Threonine dehydrogenase and related Zn-dependent dehydrogenases Transcriptional regulator GabR of GABA utilization (GntR family with aminotransferase-like domain) low-specificity D-threonine aldolase threonine dehydrogenase 02 Proline and 4-hydroxyproline A_Hypothetical_Protein_Related_to_Proline_Metabolism Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC Pyrroline-5-carboxylate reductase (EC 1.5.1.2) Proline,_4-hydroxyproline_uptake_and_utilization 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) 4-hydroxyproline epimerase (EC 5.1.1.8) Aldehyde dehydrogenase (EC 1.2.1.3) in 4-hydroxyproline catabolic gene cluster Amino acid permease in 4-hydroxyproline catabolic gene cluster D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster D-amino-acid oxidase (EC 1.4.3.3) D-proline reductase, 23 kDa subunit (EC 1.21.4.1) D-proline reductase, 26 kDa subunit (EC 1.21.4.1) D-proline reductase, 45 kDa subunit (EC 1.21.4.1) Delta 1-pyrroline-5-carboxylate dehydrogenase domain protein Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) Dipeptidyl peptidase IV in 4-hydroxyproline catabolic gene cluster Hypothetical, similar to sarcosine oxidase alpha subunit, 2Fe-2S domain Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) L-Proline/Glycine betaine transporter ProP Microbial collagenase, secreted (EC 3.4.24.3) Not a Proline racemase, nor 4-hydroxyproline epimerase [missing catalytic residues] Predicted 4-hydroxyproline dipeptidase Predicted regulator PutR for proline utilization, GntR family ProQ: influences osmotic activation of compatible solute ProP Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) Proline iminopeptidase (EC 3.4.11.5) Proline racemase (EC 5.1.1.4) Proline-specific permease proY Proline/sodium symporter PutP (TC 2.A.21.2.1) PutR, transcriptional activator of PutA and PutP Putative beta-galactosidase in 4-hydroxyproline catabolic gene cluster Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster Similar to eukaryotic Peptidyl prolyl 4-hydroxylase, alpha subunit (EC 1.14.11.2) Transcriptional repressor of PutA and PutP Ureidoglycolate/malate/sulfolactate dehydrogenase family (EC 1.1.1.-) putPA fragment of control region Proline_Synthesis Gamma-glutamyl phosphate reductase (EC 1.2.1.41) Glutamate 5-kinase (EC 2.7.2.11) NADP-specific glutamate dehydrogenase (EC 1.4.1.4) Pyrroline-5-carboxylate reductase (EC 1.5.1.2) Pyrroline-5-carboxylate reductase (EC 1.5.1.2), ProG-like 02 Creatine_and_Creatinine_Degradation Creatinase (EC 3.5.3.3) Creatinine amidohydrolase (EC 3.5.2.10) Cytosine deaminase (EC 3.5.4.1) Cytosine permease Dimethylglycine dehydrogenase (EC 1.5.99.2) N-carbamoylsarcosine amidase (EC 3.5.1.59) N-methylhydantoinase (ATP-hydrolyzing) (EC 3.5.2.14) N-methylhydantoinase A (EC 3.5.2.14) N-methylhydantoinase B (EC 3.5.2.14) Sarcosine dehydrogenase (EC 1.5.99.1) L-2-amino-thiazoline-4-carboxylic_acid-Lcysteine_conversion Beta-ureidopropionase (EC 3.5.1.6) L-2-amino-thiazoline-4-carboxylic acid hydrolase (EC 3.5.2.-) Putative N-carbamyl-L-cysteine amidohydrolase Phosphonoalanine_utilization Phosphonoalanine aminotransferase Phosphonoalanine and phosphonopyruvate utilization regulatory protein, LysR family Phosphonoalanine and/or phosphonopyruvate ABC transporter ATP-binding protein Phosphonoalanine and/or phosphonopyruvate ABC transporter periplasmic binding component Phosphonoalanine and/or phosphonopyruvate ABC transporter permease protein Phosphonopyruvate hydrolase (EC 3.11.1.3) 01 Carbohydrates 02 Aminosugars (GlcNAc)2_Catabolic_Operon (GlcNAc)2 ABC transporter, ATP-binding component 1 (GlcNAc)2 ABC transporter, ATP-binding component 2 (GlcNAc)2 ABC transporter, periplasmic substrate-binding protein (GlcNAc)2 ABC transporter, permease component 1 (GlcNAc)2 ABC transporter, permease component 2 Beta-N-acetylhexosaminidase, (GlcNAc)2 catabolism Chitin catabolic cascade sensor histidine kinase ChiS Chitobiose phosphorylase (EC 2.4.1.-) GlcNAc phosphomutase (EC 5.4.2.3) Glucosamine kinase GpsK (EC 2.7.1.8) Glucosamine-link cellobiase (EC 3.2.1.21) Chitin_and_N-acetylglucosamine_utilization Alpha-N-acetylglucosaminidase (EC 3.2.1.50) Beta-hexosaminidase (EC 3.2.1.52) Chitin binding protein Chitinase (EC 3.2.1.14) Chitobiose-specific 6-phospho-beta-glucosidase ChbF (EC 3.2.1.86) Chitobiose-specific regulator ChbR, AraC family Chitodextrinase precursor (EC 3.2.1.14) Glucosamine-6-phosphate deaminase (EC 3.5.99.6) Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) N-Acetyl-D-glucosamine ABC transport system ATP-binding protein N-Acetyl-D-glucosamine ABC transport system, permease protein 1 N-Acetyl-D-glucosamine ABC transport system, permease protein 2 N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein N-Acetyl-D-glucosamine permease 2, possible N-acetyl glucosamine transporter, NagP N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) N-acetylglucosamine regulated methyl-accepting chemotaxis protein N-acetylglucosamine related transporter, NagX N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) N-acetylglucosamine-6P-responsive transcriptional repressor NagC, ROK family N-acetylglucosamine-regulated TonB-dependent outer membrane receptor N-acetylglucosamine-regulated outer membrane porin PTS system, N-acetylglucosamine-specific IIA component (EC 2.7.1.69) PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) PTS system, chitobiose-specific IIA component (EC 2.7.1.69) PTS system, chitobiose-specific IIB component (EC 2.7.1.69) PTS system, chitobiose-specific IIC component (EC 2.7.1.69) Phosphatase NagD predicted to act in N-acetylglucosamine utilization subsystem Predicted N-acetyl-glucosamine kinase 2, ROK family (EC 2.7.1.59) Predicted chitobiose ABC transport system II, permease protein 1 Predicted chitobiose ABC transport system II, permease protein 2 Predicted chitobiose ABC transport system II, sugar-binding protein Predicted chitobiose ABC transport system, permease protein 1 Predicted chitobiose ABC transport system, permease protein 2 Predicted chitobiose ABC transport system, sugar-binding protein Predicted transcriptional regulator of N-Acetylglucosamine utilization, GntR family Predicted transcriptional regulator of N-Acetylglucosamine utilization, LacI family Regulator of chitobiose utilization ChiR, ROK family Transcriptional regulator of chitobiose utilization cluster, AraC family hypothetical oxidoreductase related to N-acetylglucosamine utilization predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59) Fructoselysine_(Amadori_product)_utilization_pathway Fructoselysine 3-epimerase Fructoselysine 6-phosphate deglycase (EC 3.5.-.-) Fructoselysine kinase (EC 2.7.1.-) Fructoselysine transporter FrlA, cationic amino acid permease Transcriptional regulator of fructoselysine utilization operon FrlR N-Acetyl-Galactosamine_and_Galactosamine_Utilization 6-phosphofructokinase (EC 2.7.1.11) Beta-galactosidase 3 Beta-hexosaminidase (EC 3.2.1.52) Beta-phosphoglucomutase (EC 5.4.2.6) Chondroitinase (chondroitin lyase) Cytoplasmic beta-galactosidase (EC 3.2.1.23) GALNS arylsulfatase regulator (Fe-S oxidoreductase) Galactosamine-6-phosphate isomerase (EC 5.3.1.-) Galactosamine-6-phosphate isomerase (galactosamine-6-phosphate deaminase) (EC 5.3.1.-) N-Acetyl-D-galactosamine permease, possible N-acetylgalactosamine 6-sulfate sulfatase (GALNS) N-acetylgalactosamine kinase, ROK-type (EC 2.7.1.157) N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.25) N-acetylgalactosamine-6-phosphate deacetylase, predicted alternative (EC 3.5.1.25) OmpC family porin possibly related to N-acetylgalactosamine utilization PTS system, N-acetylgalactosamine- and galactosamine-specific IIA component (EC 2.7.1.69) PTS system, N-acetylgalactosamine-specific IIB component (EC 2.7.1.69) PTS system, N-acetylgalactosamine-specific IIC component (EC 2.7.1.69) PTS system, N-acetylgalactosamine-specific IID component (EC 2.7.1.69) PTS system, galactosamine-specific IIB component (EC 2.7.1.69) PTS system, galactosamine-specific IIC component (EC 2.7.1.69) PTS system, galactosamine-specific IID component (EC 2.7.1.69) Predicted N-Acetyl-D-galactosamine oligosaccharide permease Predicted N-acetylgalactosamine kinase, COG2971 (EC 2.7.1.157) Predicted PTS system, galactosamine disaccharide-specific IIA component (EC 2.7.1.69) Predicted PTS system, galactosamine disaccharide-specific IIB component (EC 2.7.1.69) Predicted PTS system, galactosamine disaccharide-specific IIC component (EC 2.7.1.69) Predicted PTS system, galactosamine disaccharide-specific IID component (EC 2.7.1.69) Predicted PTS system, galactosamine-specific IIA component (EC 2.7.1.69) Predicted PTS system, galactosamine-specific IIB component (EC 2.7.1.69) Predicted PTS system, galactosamine-specific IIC component (EC 2.7.1.69) Predicted PTS system, galactosamine-specific IID component (EC 2.7.1.69) Predicted cytoplasmic N-Acetyl-D-galactosamine oligosaccharide hydrolase Predicted exported alpha-N-acetylgalactosaminidase (EC 3.2.1.49) Predicted exported glycosyl hydrolase family 31 protein Predicted secreted alpha-N-acetylgalactosaminidase (EC 3.2.1.49) Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) Tagatose-1,6-bisphosphate aldolase, alternative (EC 4.1.2.-) Tagatose-6-phosphate kinase AgaZ (EC 2.7.1.144) TonB-dependent receptor possibly related to N-acetylgalactosamine utilization TonB-dependent receptor possibly related to N-acetylgalactosamine utilization, alternative Transcriptional repressor of aga operon Neotrehalosadiamine_(NTD)_Biosynthesis_Operon NTD biosynthesis operon protein NtdA NTD biosynthesis operon putative hydrolase NtdB (EC 3.-.-.-) NTD biosynthesis operon putative oxidoreductase NtdC (EC 1.-.-.-) NTD biosynthesis operon regulator NtdR 02 CO2 fixation CO2_uptake,_carboxysome Bicarbonate transport system permease protein Bicarbonate transporter, bicarbonate binding protein Bicarbonate transporter, bicarbonate binding protein 2 Carbon dioxide concentrating mechanism protein CcmL Carbon dioxide concentrating mechanism protein CcmM Carbon dioxide concentrating mechanism protein CcmN Carbon dioxide concentrating mechanism protein CcmO Carboxysome protein CcmL Carboxysome protein CcmM Carboxysome protein CcmN High-affnity carbon uptake protein Hat/HatR Hypothetical transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5 homolog Low-affinity CO2 hydration protein CphX NADH dehydrogenase subunit 4, Involved in CO2 fixation NADH dehydrogenase subunit 5, Involved in CO2 fixation Possible RuBisCo chaperonin RbcX Possible carbon dioxide concentrating mechanism protein CcmK Possible pterin-4 alpha-carbinolamine dehydratase-like protein Ribulose bisphosphate carboxylase (EC 4.1.1.39) Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) Ribulose bisphosphate carboxylase small chain (EC 4.1.1.39) Ribulose-1,5-bisphosphate carboxylase, Type III (EC 4.1.1.39) RuBisCO operon transcriptional regulator RuBisCO operon transcriptional regulator CbbR Rubisco activation protein CbbO Rubisco activation protein CbbQ Sensory subunit of low CO2-induced protein complex, putative carboxysome shell protein CsoS1 carboxysome shell protein CsoS2 carboxysome shell protein CsoS3 probable RuBisCo-expression protein CbbX putative carboxysome peptide A putative carboxysome peptide B putative sodium-dependent bicarbonate transporter ribulose 1,5-bisphosphate carboxylase/oxygenase activase Calvin-Benson_cycle Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11) Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) Fructose-1,6-bisphosphatase, type V, archaeal (EC 3.1.3.11) Fructose-bisphosphate aldolase class I (EC 4.1.2.13) Fructose-bisphosphate aldolase class II (EC 4.1.2.13) NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal (EC 1.2.1.59) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) Phosphoglycerate kinase (EC 2.7.2.3) Phosphoribulokinase (EC 2.7.1.19) Phosphoribulokinase (EC 2.7.1.19) homolog, function unknown Protein CP12, regulation of Calvin cycle via association/dissociation of PRK/CP12/GAPDH complex Ribose 1,5-bisphosphate or 5-ribose-1,2-cyclic phosphate dehydrogenase Ribose 5-phosphate isomerase A (EC 5.3.1.6) Ribose 5-phosphate isomerase B (EC 5.3.1.6) Ribulose bisphosphate carboxylase (EC 4.1.1.39) Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) Ribulose bisphosphate carboxylase small chain (EC 4.1.1.39) Ribulose-1,5-bisphosphate carboxylase, Type III (EC 4.1.1.39) Ribulose-phosphate 3-epimerase (EC 5.1.3.1) Sedoheptulose-1,7-bisphosphatase (EC 3.1.3.37) Transketolase (EC 2.2.1.1) Transketolase, C-terminal section (EC 2.2.1.1) Transketolase, N-terminal section (EC 2.2.1.1) Triosephosphate isomerase (EC 5.3.1.1) Carboxysome Carbon dioxide concentrating mechanism protein CcmK Carbon dioxide concentrating mechanism protein CcmL Carbon dioxide concentrating mechanism protein CcmM Carbon dioxide concentrating mechanism protein CcmN Carbon dioxide concentrating mechanism protein O Carbonic anhydrase (EC 4.2.1.1) High-affnity carbon uptake protein Hat/HatR NADH dehydrogenase (EC 1.6.99.3) Phospho-2-dehydro-3-deoxyheptonate aldolase (EC 2.5.1.54) Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) Ribulose bisphosphate carboxylase small chain (EC 4.1.1.39) Photorespiration_(oxidative_C2_cycle) 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 2-oxoglutarate/malate translocator Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) Catalase (EC 1.11.1.6) D-Lactate dehydrogenase, cytochrome c-dependent (EC 1.1.2.4) D-glycerate 3-kinase (EC 2.7.1.31), plant type Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Expressed protein possibly involved in photorespiration Glycerate kinase (EC 2.7.1.31) Glycine cleavage system H protein Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2) Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2) Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD Glycolate oxidase (EC 1.1.3.15) Glycolate permease Glyoxylate carboligase (EC 4.1.1.47) Hydroxypyruvate reductase (EC 1.1.1.81) L-alanine:glyoxylate aminotransferase (EC 2.6.1.44) Malate synthase (EC 2.3.3.9) Malate synthase G (EC 2.3.3.9) Malyl-CoA lyase (EC 4.1.3.24) Phosphoglycolate phosphatase (EC 3.1.3.18) Ribulose bisphosphate carboxylase (EC 4.1.1.39) Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39) Ribulose bisphosphate carboxylase small chain (EC 4.1.1.39) Ribulose-1,5-bisphosphate carboxylase, Type III (EC 4.1.1.39) Serine hydroxymethyltransferase (EC 2.1.2.1) Serine--glyoxylate aminotransferase (EC 2.6.1.45) 02 Central carbohydrate metabolism Dehydrogenase_complexes (Pyruvate) Oxoisovalerate Dehydrogenase Alpha & Beta Fusion like 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-) Acetoin dehydrogenase E1 component beta-subunit (EC 1.2.4.-) Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Cytosol aminopeptidase PepA (EC 3.4.11.1) Dihydrolipoamide acetyltransferase component (E2) of acetoin dehydrogenase complex (EC 2.3.1.-) Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase (EC 1.8.1.4) Dihydrolipoamide dehydrogenase of acetoin dehydrogenase (EC 1.8.1.4) Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) Enoyl-CoA hydratase [branched-chain amino acid degradation] (EC 4.2.1.17) Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein Pyruvate dehydrogenase E1 component (EC 1.2.4.1) Pyruvate dehydrogenase E1 component alpha subunit (EC 1.2.4.1) Pyruvate dehydrogenase E1 component beta subunit (EC 1.2.4.1) Valine dehydrogenase (EC 1.4.1.-) Dihydroxyacetone_kinases DHA-specific EI component DHA-specific IIA component DHA-specific phosphocarrier protein HPr Dihydroxyacetone kinase, ATP-dependent (EC 2.7.1.29) Hypothetical protein in cluster with dihydroxyacetone kinase in Rhizobia Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), ADP-binding subunit DhaL Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), subunit DhaM Phosphoenolpyruvate-dihydroxyacetone phosphotransferase operon regulatory protein DhaR Putative dihydroxyacetone kinase (EC 2.7.1.29), ADP-binding subunit Putative dihydroxyacetone kinase (EC 2.7.1.29), dihydroxyacetone binding subunit Entner-Doudoroff_Pathway 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1) 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2-) 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 6-phosphogluconolactonase (EC 3.1.1.31) 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type Aldehyde dehydrogenase (EC 1.2.1.3) D-glycerate 2-kinase (EC 2.7.1.-) Enolase (EC 4.2.1.11) Glucokinase (EC 2.7.1.2) Gluconate dehydratase (EC 4.2.1.39) Gluconokinase (EC 2.7.1.12) Gluconolactonase (EC 3.1.1.17) Glucose 1-dehydrogenase (EC 1.1.1.47) Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Hexokinase (EC 2.7.1.1) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD) Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9) OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, cyanobacterial Phosphogluconate dehydratase (EC 4.2.1.12) Phosphoglycerate kinase (EC 2.7.2.3) Phosphoglycerate mutase (EC 5.4.2.1) Polyphosphate glucokinase (EC 2.7.1.63) Pyruvate kinase (EC 2.7.1.40) Ethylmalonyl-CoA_pathway_of_C2_assimilation Acetoacetyl-CoA reductase (EC 1.1.1.36) of ethylmalonyl-CoA pathway Acetyl-CoA acetyltransferase (EC 2.3.1.9) of ethylmalonyl-CoA pathway Acyltransferase family protein associated with ethylmalonyl-CoA pathway Crotonyl-CoA carboxylase/reductase, ethylmalonyl-CoA producing Ethylmalonyl-CoA mutase, methylsuccinyl-CoA-forming Hypothetical protein in cluster with Mesaconyl-CoA hydratase L-malyl-CoA/beta-methylmalyl-CoA lyase (EC 4.1.3.-) L-malyl-CoA/beta-methylmalyl-CoA lyase (EC 4.1.3.-), actinobacterial type L-malyl-CoA/beta-methylmalyl-CoA lyase (EC 4.1.3.-), chloroflexus type Mesaconyl-CoA hydratase Methylsuccinyl-CoA dehydrogenase, predicted by (Erb et al, 2007) NnrU family protein in cluster with Mesaconyl-CoA hydratase Putative cyclic di-GMP phosphodiesterase, EAL domain protein Glycolate,_glyoxylate_interconversions (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) D-Lactate dehydrogenase, cytochrome c-dependent (EC 1.1.2.4) Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD Glycolate oxidase (EC 1.1.3.15) Glycolate permease Glycolate utilization operon transcriptional activator GlcC Glyoxylate reductase (EC 1.1.1.26) Glyoxylate reductase (EC 1.1.1.79) Hydroxypyruvate reductase (EC 1.1.1.81) Hypothetical protein GlcG in glycolate utilization operon Phosphoglycolate phosphatase (EC 3.1.3.18) Phosphoglycolate phosphatase, archaeal type (EC 3.1.3.18) Putative phosphoglycolate phosphatase (EC 3.1.3.18 ) Transcriptional regulator, LysR family, in glycolate utilization operon Glycolysis_and_Gluconeogenesis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) 6-phosphofructokinase (EC 2.7.1.11) 6-phosphofructokinase class II (EC 2.7.1.11) 6-phosphofructokinase, eukaryotic type (EC 2.7.1.11) Enolase (EC 4.2.1.11) Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11) Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11) Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) Fructose-bisphosphate aldolase class I (EC 4.1.2.13) Fructose-bisphosphate aldolase class II (EC 4.1.2.13) Fructose-bisphosphate aldolase, archaeal class I (EC 4.1.2.13) Glucokinase (EC 2.7.1.2) Glucose-6-phosphate isomerase (EC 5.3.1.9) Glucose-6-phosphate isomerase, archaeal II (EC 5.3.1.9) Hexokinase (EC 2.7.1.1) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9) Phosphoenolpyruvate synthase (EC 2.7.9.2) Phosphoglycerate kinase (EC 2.7.2.3) Phosphoglycerate mutase (EC 5.4.2.1) Polyphosphate glucokinase (EC 2.7.1.63) Predicted Fructose-bisphosphate aldolase (EC 4.1.2.13) in Geobacter Putative phosphoenolpyruvate synthase/pyruvate phosphate dikinase, C-terminal domain Putative phosphoenolpyruvate synthase/pyruvate phosphate dikinase, N-terminal domain Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, alpha subunit (EC 2.7.1.90) Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, beta subunit (EC 2.7.1.90) Pyruvate kinase (EC 2.7.1.40) Pyruvate,phosphate dikinase (EC 2.7.9.1) Triosephosphate isomerase (EC 5.3.1.1) Glycolysis_and_Gluconeogenesis,_including_Archaeal_enzymes 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1) 6-phosphofructokinase (EC 2.7.1.11) ADP-dependent glucokinase (EC 2.7.1.147) ADP-dependent phosphofructokinase (EC 2.7.1.146) Enolase (EC 4.2.1.11) Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11) Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) Fructose-1,6-bisphosphatase, type V, archaeal (EC 3.1.3.11) Fructose-bisphosphate aldolase, archaeal class I (EC 4.1.2.13) Glucose-6-phosphate isomerase (EC 5.3.1.9) Glucose-6-phosphate isomerase, archaeal (EC 5.3.1.9) Glucose-6-phosphate isomerase, archaeal II (EC 5.3.1.9) Glyceraldehyde-3-phosphate: ferredoxin oxidoreductase (EC 1.2.7.6) Hexokinase (EC 2.7.1.1) NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal (EC 1.2.1.59) Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD) Phosphoenolpyruvate synthase (EC 2.7.9.2) Phosphoglycerate kinase (EC 2.7.2.3) Phosphoglycerate mutase (EC 5.4.2.1) Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, alpha subunit (EC 2.7.1.90) Pyruvate kinase (EC 2.7.1.40) Pyruvate,phosphate dikinase (EC 2.7.9.1) Triosephosphate isomerase (EC 5.3.1.1) Glyoxylate_bypass (R)-2-hydroxyacid dehydrogenase, similar to L-sulfolactate dehydrogenase (EC 1.1.1.272) Aconitate hydratase (EC 4.2.1.3) Aconitate hydratase 2 (EC 4.2.1.3) Citrate synthase (si) (EC 2.3.3.1) Citrate synthase, mitochondrial precursor (EC 2.3.3.1) Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) Isocitrate lyase (EC 4.1.3.1) Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2 Malate dehydrogenase (EC 1.1.1.37) Malate synthase (EC 2.3.3.9) Malate synthase G (EC 2.3.3.9) Methylglyoxal_Metabolism Aldehyde dehydrogenase (EC 1.2.1.3) Aldehyde dehydrogenase A (EC 1.2.1.22) Aldehyde dehydrogenase B (EC 1.2.1.22) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Lactoylglutathione lyase (EC 4.4.1.5) Methylglyoxal synthase (EC 4.2.3.3) NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase) Particulate_methane_monooxygenase_(pMMO) Particulate methane monooxygenase A-subunit (EC 1.14.13.25) Particulate methane monooxygenase B-subunit (EC 1.14.13.25) Particulate methane monooxygenase C-subunit (EC 1.14.13.25) Pentose_phosphate_pathway 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) 6-phosphogluconolactonase (EC 3.1.1.31) 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type Fructose-6-phosphate phosphoketolase (EC 4.1.2.22) Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Ribose 5-phosphate isomerase A (EC 5.3.1.6) Ribose 5-phosphate isomerase B (EC 5.3.1.6) Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) Ribulose-phosphate 3-epimerase (EC 5.1.3.1) Transaldolase (EC 2.2.1.2) Transketolase (EC 2.2.1.1) Transketolase, C-terminal section (EC 2.2.1.1) Transketolase, N-terminal section (EC 2.2.1.1) Xylulose-5-phosphate phosphoketolase (EC 4.1.2.9) Peripheral_Glucose_Catabolism_Pathways DNA-binding response regulator GltR, controls specific porins for the entry of glucose Glucokinase (EC 2.7.1.2) Glucose ABC transport system, inner membrane component 1 Glucose ABC transport system, inner membrane component 2 Glucose ABC transport system, periplasmic sugar-binding protein Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) Glucose-selective porin OprB Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster Pyruvate:ferredoxin_oxidoreductase Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) Pyruvate:ferredoxin oxidoreductase, alpha subunit (EC 1.2.7.1) Pyruvate:ferredoxin oxidoreductase, beta subunit (EC 1.2.7.1) Pyruvate:ferredoxin oxidoreductase, delta subunit (EC 1.2.7.1) Pyruvate:ferredoxin oxidoreductase, gamma subunit (EC 1.2.7.1) Pyruvate:ferredoxin oxidoreductase, porE subunit (EC 1.2.7.1) Pyruvate:ferredoxin oxidoreductase, porF subunit (EC 1.2.7.1) Pyruvate_Alanine_Serine_Interconversions Alanine dehydrogenase (EC 1.4.1.1) Alanine racemase (EC 5.1.1.1) Alanine racemase, biosynthetic (EC 5.1.1.1) Alanine racemase, catabolic (EC 5.1.1.1) Branched-chain amino acid aminotransferase (EC 2.6.1.42) D-alanine aminotransferase (EC 2.6.1.21) D-amino acid dehydrogenase small subunit (EC 1.4.99.1) D-serine dehydratase (EC 4.3.1.18) D-serine/D-alanine/glycine transporter L-alanine:glyoxylate aminotransferase (EC 2.6.1.44) L-serine dehydratase (EC 4.3.1.17) L-serine dehydratase, alpha subunit (EC 4.3.1.17) L-serine dehydratase, beta subunit (EC 4.3.1.17) Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) Predicted L-serine dehydratase (EC 4.3.1.17) TdcG Serine transporter Valine--pyruvate aminotransferase (EC 2.6.1.66) Pyruvate_metabolism_I:_anaplerotic_reactions,_PEP Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate Biotin carboxyl carrier protein of oxaloacetate decarboxylase D-malic enzyme (EC 1.1.1.83) Malate Na(+) symporter Malate permease Malolactic enzyme (EC 1.-.-.-) Malolactic regulator Membrane protein associated with oxaloacetate decarboxylase NAD-dependent malic enzyme (EC 1.1.1.38) NADP-dependent malic enzyme (EC 1.1.1.40) Oxaloacetate decarboxylase alpha chain (EC 4.1.1.3) Oxaloacetate decarboxylase beta chain (EC 4.1.1.3) Oxaloacetate decarboxylase gamma chain (EC 4.1.1.3) Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) Phosphoenolpyruvate carboxylase (EC 4.1.1.31) Phosphoenolpyruvate carboxylase, archaeal (EC 4.1.1.31) Phosphoenolpyruvate synthase (EC 2.7.9.2) Positive regulator of Tartrate dehydrogenase/decarboxylase/D-malic enzyme Pyruvate carboxyl transferase (EC 6.4.1.1) Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) Pyruvate kinase (EC 2.7.1.40) Pyruvate,phosphate dikinase (EC 2.7.9.1) Two-component response regulator, malate (EC 2.7.3.-) Two-component sensor histidine kinase, malate (EC 2.7.3.-) Pyruvate_metabolism_II:_acetyl-CoA,_acetogenesis_from_pyruvate Acetaldehyde dehydrogenase (EC 1.2.1.10) Acetate kinase (EC 2.7.2.1) Acetate permease ActP (cation/acetate symporter) Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative Acetyl-CoA synthetase (ADP-forming) alpha chain (EC 6.2.1.13) Acetyl-CoA synthetase (ADP-forming) beta chain (EC 6.2.1.13) Acetyl-coenzyme A synthetase (EC 6.2.1.1) Acetyltransferase AcuA, acetyl-CoA synthetase inhibitor Acylphosphate phosphohydrolase (EC 3.6.1.7), putative Aldehyde dehydrogenase (EC 1.2.1.3) Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) Lactate 2-monooxygenase (EC 1.13.12.4) NAD-dependent protein deacetylase of SIR2 family NAD-independent protein deacetylase AcuC Phosphate acetyltransferase (EC 2.3.1.8) Protein acetyltransferase Putative membrane protein, clustering with ActP Pyruvate decarboxylase (EC 4.1.1.1) Pyruvate dehydrogenase E1 component (EC 1.2.4.1) Pyruvate dehydrogenase E1 component alpha subunit (EC 1.2.4.1) Pyruvate dehydrogenase E1 component beta subunit (EC 1.2.4.1) Pyruvate oxidase (EC 1.2.3.3) Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2) Soluble_methane_monooxygenase_(sMMO) Methane monooxygenase component A alpha chain (EC 1.14.13.25) Methane monooxygenase component A beta chain (EC 1.14.13.25) Methane monooxygenase component A gamma chain (EC 1.14.13.25) Methane monooxygenase component C (EC 1.14.13.25) Methane monooxygenase component D (EC 1.14.13.25) Methane monooxygenase regulatory protein B TCA_Cycle 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) Aconitate hydratase (EC 4.2.1.3) Aconitate hydratase 2 (EC 4.2.1.3) Aconitate hydratase X, predicted Aconitate hydratase large subunit (EC 4.2.1.3) Aconitate hydratase small subunit (EC 4.2.1.3) Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) Archaeal succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) Citrate lyase gamma chain, acyl carrier protein (EC 4.1.3.6) Citrate synthase (si) (EC 2.3.3.1) Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase (EC 1.8.1.4) Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) Fumarate hydratase class I (EC 4.2.1.2) Fumarate hydratase class I, aerobic (EC 4.2.1.2) Fumarate hydratase class II (EC 4.2.1.2) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) Isocitrate dehydrogenase [NAD] (EC 1.1.1.41) Malate dehydrogenase (EC 1.1.1.37) Malate:quinone oxidoreductase (EC 1.1.5.4) Putative Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Putative malate dehydrogenase (EC 1.1.1.37), similar to archaeal MJ1425 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) Transcriptional regulator of succinyl CoA synthetase operon hypothetical protein that often co-occurs with aconitase 02 Di- and oligosaccharides Beta-Glucoside_Metabolism 6-phospho-beta-glucosidase (EC 3.2.1.86) 6-phospho-beta-glucosidase ascB (EC 3.2.1.86) AscBF operon repressor Beta-glucanase precursor (EC 3.2.1.73) Beta-glucosidase (EC 3.2.1.21) Beta-glucoside ABC transport system, ATP-binding protein 1 Beta-glucoside ABC transport system, ATP-binding protein 2 Beta-glucoside ABC transport system, permease protein 1 Beta-glucoside ABC transport system, permease protein 2 Beta-glucoside ABC transport system, sugar-binding protein Beta-glucoside bgl operon antiterminator, BglG family Cellobiose phosphorylase (EC 2.4.1.-) Cellobiose phosphotransferase system YdjC-like protein Cellobiose-responsive regulator of beta-glucosides utilization, ROK family Cytoplasmic endo-1,4-beta-glucanase (EC 3.2.1.4) Endo-beta-1,3-1,4 glucanase (Licheninase) (EC 3.2.1.73) Extracellular endo-1,4-beta-glucanase (EC 3.2.1.4) Glucokinase, ROK family (EC 2.7.1.2) Glucose ABC transporter, ATP-binding component Glucose ABC transporter, permease component Glucose ABC transporter, substrate-binding component Laminarinase (EC 3.2.1.39) Methyl-accepting chemotaxis protein co-located with beta-glucan transporter system Negative transcriptional regulator of cel operon Outer surface protein of unknown function, cellobiose operon PTS system, arbutin-, cellobiose-, and salicin-specific IIBC component (EC 2.7.1.69) PTS system, beta-glucoside-specific IIA component (EC 2.7.1.69) PTS system, beta-glucoside-specific IIB component (EC 2.7.1.69) PTS system, beta-glucoside-specific IIC component (EC 2.7.1.69) PTS system, cellobiose-specific IIA component (EC 2.7.1.69) PTS system, cellobiose-specific IIB component (EC 2.7.1.69) PTS system, cellobiose-specific IIC component (EC 2.7.1.69) PTS system, diacetylchitobiose-specific IIA component (EC 2.7.1.6 PTS system, diacetylchitobiose-specific IIB component (EC 2.7.1.69) PTS system, diacetylchitobiose-specific IIC component (EC 2.7.1.69) Periplasmic beta-glucosidase (EC 3.2.1.21) Predicted aldo/keto reductase in CelR regulon, COG4989 Predicted beta-glucoside specific TonB-dependent outer membrane receptor Predicted beta-glucoside transporter, GPH family Predicted beta-glucoside-regulated ABC transport system, permease component 1, COG1175 Predicted beta-glucoside-regulated ABC transport system, permease component 2, COG0395 Predicted beta-glucoside-regulated ABC transport system, sugar binding component, COG1653 Predicted beta-glucosides ABC transporter, permease protein 1 Predicted beta-glucosides ABC transporter, permease protein 2 Predicted beta-glucosides ABC transporter, substrate binding prot Predicted cellobiose ABC transport system, ATP-binding protein 1 Predicted cellobiose ABC transport system, ATP-binding protein 2 Predicted cellobiose ABC transport system, permease protein 1 Predicted cellobiose ABC transport system, permease protein 2 Predicted cellobiose ABC transport system, sugar-binding protein Predicted dehydrogenase in CelR regulon, COG0673 Predicted glucose transporter in beta-glucoside utilization gene cluster Predicted regulator Pmob_1925 of beta-glucosides utilization, ROK family Predicted regulator of cellobiose and glucan utilization, LacI family Predicted regulator of glucose and trehalose utilization, ROK family Transcriptional antiterminator of lichenan operon, BglG family Transcriptional regulator of beta-glucosides utilization, LacI family Fructooligosaccharides(FOS)_and_Raffinose_Utilization Alpha-galactosidase (EC 3.2.1.22) Alpha-mannosidase (EC 3.2.1.24) Beta-glucosidase (EC 3.2.1.21) Glucan 1,6-alpha-glucosidase (EC 3.2.1.70) Hyaluronoglucosaminidase (EC 3.2.1.35) Lactose permease MSM (multiple sugar metabolism) operon regulatory protein Multiple sugar ABC transporter, ATP-binding protein Multiple sugar ABC transporter, membrane-spanning permease protein MsmF Multiple sugar ABC transporter, membrane-spanning permease protein MsmG Multiple sugar ABC transporter, substrate-binding protein Raffinose operon transcriptional regulatory protein RafR Raffinose permease Sucrose phosphorylase (EC 2.4.1.7) Sucrose-6-phosphate hydrolase (EC 3.2.1.26) Two-component sensor kinase YesM (EC 2.7.3.-) Lactose_and_Galactose_Uptake_and_Utilization 6-phospho-beta-galactosidase (EC 3.2.1.85) Aldose 1-epimerase (EC 5.1.3.3) Alpha-galactosidase (EC 3.2.1.22) Arabinogalactan endo-1,4-beta-galactosidase (EC 3.2.1.89) Beta-galactosidase (EC 3.2.1.23) Beta-galactosidase (EC 3.2.1.23), LacA family Beta-galactosidase (EC 3.2.1.23), LacZ family Beta-galactosidase large subunit (EC 3.2.1.23) Beta-galactosidase small subunit (EC 3.2.1.23) Galactokinase (EC 2.7.1.6) Galactose operon repressor, GalR-LacI family of transcriptional regulators Galactose permease Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10) Galactose-6-phosphate isomerase, LacA subunit (EC 5.3.1.26) Galactose-6-phosphate isomerase, LacB subunit (EC 5.3.1.26) Galactose/methyl galactoside ABC transport system, ATP-binding protein MglA (EC 3.6.3.17) Galactose/methyl galactoside ABC transport system, D-galactose-binding periplasmic protein MglB (TC 3.A.1.2.3) Galactose/methyl galactoside ABC transport system, permease protein MglC (TC 3.A.1.2.3) Lactose and galactose permease, GPH translocator family Lactose permease Lactose phosphotransferase system repressor Mgl repressor and galactose ultrainduction factor GalS, HTH-type transcriptional regulator PTS system, galactose-specific IIA component (EC 2.7.1.69) PTS system, galactose-specific IIB component (EC 2.7.1.69) PTS system, galactose-specific IIC component (EC 2.7.1.69) PTS system, lactose-specific IIA component (EC 2.7.1.69) PTS system, lactose-specific IIB component (EC 2.7.1.69) PTS system, lactose-specific IIC component (EC 2.7.1.69) Predicted galactoside ABC transporter type II, permease protein 1 Predicted galactoside ABC transporter type II, permease protein 2 Predicted galactoside ABC transporter type II, sugar-binding protein Predicted galactoside ABC transporter, ATP-binding protein 1 Predicted galactoside ABC transporter, ATP-binding protein 2 Predicted galactoside ABC transporter, permease protein 1 Predicted galactoside ABC transporter, permease protein 2 Predicted galactoside ABC transporter, sugar-binding protein Predicted regulator of galactoside utilization, LacI family Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) Tagatose-6-phosphate kinase (EC 2.7.1.144) Transcriptional repressor of the lac operon UDP-glucose 4-epimerase (EC 5.1.3.2) Lactose_utilization Beta-galactosidase (EC 3.2.1.23) Evolved beta-D-galactosidase transcriptional repressor Evolved beta-D-galactosidase, alpha subunit Evolved beta-D-galactosidase, beta subunit Galactoside O-acetyltransferase (EC 2.3.1.18) Lactose and galactose permease, GPH translocator family Lactose permease Transcriptional repressor of the lac operon Maltose_and_Maltodextrin_Utilization 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25) 4-alpha-glucanotransferase MgtA (EC 2.4.1.25) ABC-type sugar transport system, periplasmic binding protein YcjN Aldose 1-epimerase (EC 5.1.3.3) Alpha-amylase (EC 3.2.1.1) Alpha-glucosidase (EC 3.2.1.20) Beta-phosphoglucomutase (EC 5.4.2.6) Cytoplasmic alpha-amylase (EC 3.2.1.1) Glucoamylase (EC 3.2.1.3) Glycogen phosphorylase (EC 2.4.1.1) Inner membrane ABC transporter permease protein YcjO Inner membrane ABC transporter permease protein YcjP Malto-oligosyltrehalose synthase (EC 5.4.99.15) Maltodextrin glucosidase (EC 3.2.1.20) Maltodextrin glycosyltransferase MmtA Maltodextrin phosphorylase (EC 2.4.1.1) Maltodextrose utilization protein MalA Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein) Maltose O-acetyltransferase (EC 2.3.1.79) Maltose oligosaccharide ABC transporter, permease protein MalF1 Maltose oligosaccharide ABC transporter, permease protein MalG1 Maltose oligosaccharide ABC transporter, substrate binding periplasmic protein MalE1 Maltose operon periplasmic protein MalM Maltose operon transcriptional repressor MalR, LacI family Maltose phosphorylase (EC 2.4.1.8) Maltose regulon modulator Maltose regulon regulatory protein MalI (repressor for malXY) Maltose-6'-phosphate glucosidase (EC 3.2.1.122) Maltose/maltodextrin ABC transporter 2, permease protein MalF2 Maltose/maltodextrin ABC transporter 2, permease protein MalG2 Maltose/maltodextrin ABC transporter 2, substrate binding periplasmic protein MalE2 Maltose/maltodextrin ABC transporter, permease protein MalF Maltose/maltodextrin ABC transporter, permease protein MalG Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE Maltose/maltodextrin transport ATP-binding protein MalK (EC 3.6.3.19) Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon Multiple sugar ABC transporter, ATP-binding protein Neopullulanase (EC 3.2.1.135) Oligo-1,6-glucosidase (EC 3.2.1.10) PTS system, maltose and glucose-specific IIA component (EC 2.7.1.69) PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69) PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69) Periplasmic alpha-amylase (EC 3.2.1.1) Predicted glucose transporter in maltodextrin utilization gene cluster Predicted maltose transporter MalT Predicted maltose-specific TonB-dependent receptor Pullulanase (EC 3.2.1.41) Putative oxidoreductase YcjS (EC 1.-.-.-), NADH-binding Putative sucrose phosphorylase (EC 2.4.1.7) Sugar phosphate isomerases/epimerases family protein YcjR Transcriptional activator of maltose regulon, MalT Transcriptional regulator YcjW, LacI family, possibly involved in maltodextrin utilization pathway Transcriptional regulator of maltose utilization, LacI family Zinc-type alcohol dehydrogenase YcjQ Melibiose_Utilization Alpha-galactosidase (EC 3.2.1.22) Melibiose carrier protein, Na+/melibiose symporter Melibiose operon regulatory protein Sucrose_utilization Family 13 glycosyl hydrolase, row 724 Fructokinase (EC 2.7.1.4) PTS system, sucrose-specific IIA component (EC 2.7.1.69) PTS system, sucrose-specific IIB component (EC 2.7.1.69) PTS system, sucrose-specific IIC component (EC 2.7.1.69) Predicted sucrose permease, MFS family, FucP subfamily Predicted sucrose-specific TonB-dependent receptor Sucrose operon repressor ScrR, LacI family Sucrose permease, major facilitator superfamily Sucrose phosphorylase (EC 2.4.1.7) Sucrose repressor, LacI family, Shewanella subfamily Sucrose specific transcriptional regulator CscR, LacI family Sucrose-6-phosphate hydrolase (EC 3.2.1.26) Sucrose_utilization_Shewanella Fructokinase (EC 2.7.1.4) Predicted sucrose permease, MFS family, FucP subfamily Predicted sucrose-specific TonB-dependent receptor Sucrose phosphorylase (EC 2.4.1.7) Sucrose repressor, LacI family, Shewanella subfamily Trehalose_Biosynthesis 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15) Alpha-amylase (EC 3.2.1.1) Glucoamylase (EC 3.2.1.3) Glycogen debranching enzyme (EC 3.2.1.-) Malto-oligosyltrehalose synthase (EC 5.4.99.15) Malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141) Putative glucanase glgE (EC 3.2.1.-) Trehalose phosphorylase (EC 2.4.1.64) Trehalose synthase (EC 5.4.99.16) Trehalose-6-phosphate phosphatase (EC 3.1.3.12) Trehalose_Uptake_and_Utilization Beta-phosphoglucomutase (EC 5.4.2.6) Cytoplasmic trehalase (EC 3.2.1.28) Glucose/mannose:H+ symporter GlcP Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein) Maltose-6'-phosphate glucosidase (EC 3.2.1.122) PTS system, glucose-specific IIA component (EC 2.7.1.69) PTS system, glucose-specific IIB component (EC 2.7.1.69) PTS system, glucose-specific IIC component (EC 2.7.1.69) PTS system, trehalose-specific IIA component (EC 2.7.1.69) PTS system, trehalose-specific IIB component (EC 2.7.1.69) PTS system, trehalose-specific IIC component (EC 2.7.1.69) Predicted trehalose ABC transporter, permease component 1, Archaea-type Predicted trehalose ABC transporter, permease component 2, Archaea-type Predicted trehalose ABC transporter, substrate-binding component, Archaea-type Predicted trehalose permease, MFS family Predicted trehalose permease, MFS family, FucP subfamily Probable transcriptional regulator of trehalose utilization, LuxR family Putative cytoplasmic protein clustered with trehalase Regulator of trehalose utilization TreR, ROK family Transcriptional regulator of trehalose utilization, LacI family Trehalase (EC 3.2.1.28) Trehalose 6-phosphate phosphorylase (EC 2.4.1.216) Trehalose operon transcriptional repressor Trehalose phosphorylase (EC 2.4.1.64) Trehalose synthase, nucleoside diphosphate glucose dependent Trehalose-6-phosphate hydrolase (EC 3.2.1.93) Trehalose-regulated TonB-dependent outer membrane receptor Unknown_oligosaccharide_utilization_Sde_1396 1st GPH family transporter in unknown oligosaccharide utilization Sde 1396 2nd GPH family transporter in unknown oligosaccharide utilization Sde 1396 Family 1 glycosyl hydrolase, row 954 Family 3 glycosyl hydrolase in unknown oligosaccharide utilization Sde 1396 LacI family transcriptional regulator, row 218 TonB-dependent receptor in unknown oligosaccharide utilization Sde 1396 02 Fermentation Acetoin,_butanediol_metabolism 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4) 2,3-butanediol dehydrogenase, S-alcohol forming, (R)-acetoin-specific (EC 1.1.1.4) 2,3-butanediol dehydrogenase, S-alcohol forming, (S)-acetoin-specific (EC 1.1.1.76) Acetoin (diacetyl) reductase (EC 1.1.1.5) Acetoin catabolism protein X Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-) Acetoin dehydrogenase E1 component beta-subunit (EC 1.2.4.-) Acetolactate synthase large subunit (EC 2.2.1.6) Acetolactate synthase small subunit (EC 2.2.1.6) Acetolactate synthase small subunit (EC 2.2.1.6), predicted Acetolactate synthase small subunit (EC 2.2.1.6), predicted, Archaeal type Acetolactate synthase small subunit (EC 2.2.1.6), predicted, Archaeal type 2 Acetolactate synthase, catabolic (EC 2.2.1.6) Alpha-acetolactate decarboxylase (EC 4.1.1.5) Dihydrolipoamide acetyltransferase component (E2) of acetoin dehydrogenase complex (EC 2.3.1.-) Dihydrolipoamide dehydrogenase of acetoin dehydrogenase (EC 1.8.1.4) Transcriptional activator of acetoin dehydrogenase operon AcoR Acetone_Butanol_Ethanol_Synthesis 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) Acetaldehyde dehydrogenase (EC 1.2.1.10) Acetoacetate decarboxylase (EC 4.1.1.4) Acetoacetate metabolism regulatory protein AtoC Acetyl-CoA acetyltransferase (EC 2.3.1.9) Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (EC 2.8.3.8) Acetyl-CoA:acetoacetyl-CoA transferase, beta subunit (EC 2.8.3.8) Alcohol dehydrogenase (EC 1.1.1.1) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Electron transfer flavoprotein, alpha subunit Electron transfer flavoprotein, beta subunit NADH-dependent butanol dehydrogenase (EC 1.1.1.-) NADH-dependent butanol dehydrogenase A (EC 1.1.1.-) NADH-dependent butanol dehydrogenase B (EC 1.1.1.-) Acetyl-CoA_fermentation_to_Butyrate 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) Acetoacetate metabolism regulatory protein AtoC Acetoacetyl-CoA reductase (EC 1.1.1.36) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (EC 2.8.3.8) Acetyl-CoA:acetoacetyl-CoA transferase, beta subunit (EC 2.8.3.8) Butyrate kinase (EC 2.7.2.7) Butyrate-acetoacetate CoA-transferase subunit A (EC 2.8.3.9) Butyrate-acetoacetate CoA-transferase subunit B (EC 2.8.3.9) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Electron transfer flavoprotein, alpha subunit Electron transfer flavoprotein, beta subunit Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1) Enoyl-CoA hydratase (EC 4.2.1.17) Ferredoxin-like protein Ferredoxin-like protein FixX Ferredoxin-like protein YdiT Ferredoxin-like protein YgcO Probable electron transfer flavoprotein-quinone oxidoreductase FixC (EC 1.5.5.-) phosphotransbutyrylase (EC 2.3.1.19) Butanol_Biosynthesis 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) Acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Enoyl-CoA hydratase (EC 4.2.1.17) NADH-dependent butanol dehydrogenase A (EC 1.1.1.-) NADH-dependent butanol dehydrogenase B (EC 1.1.1.-) NADPH-dependent butanol dehydrogenase (EC 1.1.1.-) Pyruvate formate-lyase (EC 2.3.1.54) Fermentations:_Lactate Acetaldehyde dehydrogenase (EC 1.2.1.10) Acetate kinase (EC 2.7.2.1) D-lactate dehydrogenase (EC 1.1.1.28) Fructose-6-phosphate phosphoketolase (EC 4.1.2.22) L-lactate dehydrogenase (EC 1.1.1.27) Phosphate acetyltransferase (EC 2.3.1.8) Xylulose-5-phosphate phosphoketolase (EC 4.1.2.9) Fermentations:_Mixed_acid Acetaldehyde dehydrogenase (EC 1.2.1.10) Acetate kinase (EC 2.7.2.1) Alcohol dehydrogenase (EC 1.1.1.1) D-lactate dehydrogenase (EC 1.1.1.28) Formate efflux transporter (TC 2.A.44 family) L-lactate dehydrogenase (EC 1.1.1.27) Phosphate acetyltransferase (EC 2.3.1.8) Phosphoenolpyruvate carboxylase (EC 4.1.1.31) Phosphoenolpyruvate carboxylase, archaeal (EC 4.1.1.31) Pyruvate formate-lyase (EC 2.3.1.54) Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) Sugar/maltose fermentation stimulation protein homolog 02 Glycoside hydrolases Predicted_carbohydrate_hydrolases COG1306 predicted glycoside hydrolase COG1649 predicted glycoside hydrolase COG2152 predicted glycoside hydrolase Carbohydrate Esterase Family 4 Peptidoglycan N-acetylglucosamine deacetylase (EC 3.5.1.-) Polysaccharide deacetylase Polysaccharide intercellular adhesin (PIA) biosynthesis deacetylase IcaB (EC 3.-.-.-) 02 Monosaccharides 2-Ketogluconate_Utilization 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 2-ketogluconate kinase (EC 2.7.1.13) 2-ketogluconate transporter 2-ketogluconate utilization repressor PtxS Epimerase KguE HTH-type transcriptional regulator PtxR D-Galacturonate_and_D-Glucuronate_Utilization 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) 2-keto-3-deoxygluconate permease (KDG permease) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC 5.3.1.17) 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) Alcohol dehydrogenase, zinc-containing Alpha-1,4-digalacturonate ABC transporter, permease protein 1 Alpha-1,4-digalacturonate ABC transporter, permease protein 2 Alpha-1,4-digalacturonate ABC transporter, substrate-binding protein Alpha-glucosidase (EC 3.2.1.20) Alpha-glucuronidase (EC 3.2.1.139) Altronate hydrolase (EC 4.2.1.7) Altronate oxidoreductase (EC 1.1.1.58) Beta-glucuronidase (EC 3.2.1.31) Carbohydrate-binding, CenC domain protein D-galactarate dehydratase (EC 4.2.1.42) D-mannonate oxidoreductase (EC 1.1.1.57) Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8) Exopolygalacturonate lyase (EC 4.2.2.9) Fructuronate transporter GntP Galacturan 1,4-alpha-galacturonidase (EC 3.2.1.67) Glucuronide permease Glucuronide transport facilitator UidC Glucuronide transporter UidB Hexuronate transporter Hexuronate utilization operon transcriptional repressor ExuR Intracellular alpha-amylase (EC 3.2.1.1) Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) Mannonate dehydratase (EC 4.2.1.8) Novel D-mannonate dehydrogenase (EC 1.1.1.57) Novel D-mannonate-D-gluconate epimerase Novel D-tagaturonate epimerase Oligogalacturonate lyase (EC 4.2.2.6) Oligogalacturonate-specific porin protein KdgM Pectate lyase precursor (EC 4.2.2.2) Pectin degradation protein KdgF Pectin lyase (EC 4.2.2.10) Pectinesterase (EC 3.1.1.11) Polygalacturonase (EC 3.2.1.15) Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family Predicted D-glucuronide-specific TRAP transporter, large transmembrane component Predicted D-glucuronide-specific TRAP transporter, small transmembrane component Predicted D-glucuronide-specific TRAP transporter, substrate-binding component Putative methyl oligogalcturonate esterase Regulator of pectin and galacturonate utilization, GntR family Rhamnogalacturonides degradation protein RhiN Transcriptional regulator KdgR, KDG operon repressor Transcriptional repressor UidR Uronate dehydrogenase (EC 1.1.1.203) Uronate isomerase (EC 5.3.1.12) Uronate isomerase, family BH0493 (EC 5.3.1.12) Uxu operon transcriptional regulator Xylan oligosaccharide ABC transporter, ATP-binding protein 1 Xylan oligosaccharide ABC transporter, substrate-binding component Xylan oligosaccharide ABC transporter, ATP-binding protein 2 Xylan oligosaccharide ABC transporter, permease component 1 Xylan oligosaccharide ABC transporter, permease component 2 D-Sorbitol(D-Glucitol)_and_L-Sorbose_Utilization Glucitol operon GutQ protein Glucitol operon activator protein Glucitol operon repressor Glucitol/sorbitol-specific transport protein GutA L-sorbose 1-phosphate reductase (EC 1.1.1.-) PTS system, glucitol/sorbitol-specific IIA component (EC 2.7.1.69) PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components (EC 2.7.1.69) PTS system, glucitol/sorbitol-specific IIC component (EC 2.7.1.69) PTS system, sorbose-specific IIA component (EC 2.7.1.69) PTS system, sorbose-specific IIB component (EC 2.7.1.69) PTS system, sorbose-specific IIC component (EC 2.7.1.69) PTS system, sorbose-specific IID component (EC 2.7.1.69) Putative transcriptional regulator of sorbose uptake and utilization genes Sorbitol operon transcription regulator Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) D-Tagatose_and_Galactitol_Utilization 6-phosphofructokinase (EC 2.7.1.11) D-tagatose 3-epimerase (EC 5.3.1.-) Galactitol utilization operon repressor Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251) PTS system, galactitol-specific IIA component (EC 2.7.1.69) PTS system, galactitol-specific IIB component (EC 2.7.1.69) PTS system, galactitol-specific IIC component (EC 2.7.1.69) PTS system, tagatose-specific IIA-TPr component (EC 2.7.1.69) PTS system, tagatose-specific IIBC component (EC 2.7.1.69) Predicted galactitol operon regulator (Transcriptional antiterminator), BglG family Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) Tagatose-1-phosphate kinase TagK Tagatose-6-phosphate kinase (EC 2.7.1.144) Tagatose-6-phosphate kinase GatZ (EC 2.7.1.144) D-allose_utilization D-allose ABC transporter, ATPase component D-allose ABC transporter, permease component D-allose ABC transporter, substrate-binding component D-allose kinase (EC 2.7.1.55) D-allose-6-phosphate isomerase (EC 5.3.1.-) D-allulose-6-phosphate 3-epimerase (EC 5.1.3.-), row_id 1016 D-allulose-6-phosphate 3-epimerase (EC 5.1.3.-), row_id 846 PTS system, D-allose-specific IIA component (EC 2.7.1.69) PTS system, D-allose-specific IIB component (EC 2.7.1.69) PTS system, D-allose-specific IIC component (EC 2.7.1.69) Transcriptional regulator of D-allose utilization, LacI family Transcriptional regulator of D-allose utilization, RpiR family D-galactarate,_D-glucarate_and_D-glycerate_catabolism 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) D-galactarate dehydratase (EC 4.2.1.42) D-galactarate permease D-glucarate permease D-glycerate 2-kinase (EC 2.7.1.-) D-glycerate transporter (predicted) Glucarate dehydratase (EC 4.2.1.40) Glycerate kinase (EC 2.7.1.31) Predicted 5-dehydro-4-deoxyglucarate regulator YcbG Predicted D-glucarate or D-galactorate regulator, GntR family Predicted D-glucarate or D-galactorate regulator, IclR family Sugar diacid utilization regulator SdaR D-galactonate_catabolism 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58) 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) D-Galactonate repressor DgoR D-galactonate regulator, IclR family D-galactonate transporter Galactonate dehydratase (EC 4.2.1.6) D-gluconate_and_ketogluconates_metabolism 2,5-diketo-D-gluconate reductase A (EC 1.1.1.274) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274) 2-Keto-D-gluconate dehydrogenase (EC 1.1.99.4), membrane-bound, cytochrome c 2-Keto-D-gluconate dehydrogenase (EC 1.1.99.4), membrane-bound, flavoprotein 2-Keto-D-gluconate dehydrogenase (EC 1.1.99.4), membrane-bound, gamma subunit 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) Broad-specificity glycerol dehydrogenase (EC 1.1.99.22), subunit SldA Broad-specificity glycerol dehydrogenase (EC 1.1.99.22), subunit SldB Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, cytochrome c Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, flavoprotein Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, gamma subunit Gluconate operon transcriptional repressor Gluconate permease Gluconate permease, Bsu4004 homolog Gluconate transporter family protein Gluconate utilization system Gnt-I transcriptional repressor Gluconokinase (EC 2.7.1.12) Glucose 1-dehydrogenase (EC 1.1.1.47) Glucose dehydrogenase (EC 1.1.99.10), membrane-bound, cytochrome c Glucose dehydrogenase (EC 1.1.99.10), membrane-bound, flavoprotein Glucose dehydrogenase (EC 1.1.99.10), membrane-bound, gamma subunit Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) High-affinity gluconate transporter GntT Hypothetical oxidoreductase YqhD (EC 1.1.-.-) Hypothetical transcriptional regulator YqhC L-idonate 5-dehydrogenase (EC 1.1.1.264) L-idonate, D-gluconate, 5-keto-D-gluconate transporter Low-affinity gluconate/H+ symporter GntU Positive regulator of L-idonate catabolism Predicted gluconate TRAP family transporter, DctM subunit Predicted gluconate TRAP family transporter, DctP subunit Predicted gluconate TRAP family transporter, DctQ subunit D-ribose_utilization Predicted nucleoside ABC transporter, ATP-binding component Predicted nucleoside ABC transporter, permease 1 component Predicted nucleoside ABC transporter, permease 2 component Predicted nucleoside ABC transporter, substrate-binding component Predicted regulator of ribose utilization, LacI family Putative ribose uptake protein RbsU, GRP transporter family (TC 2.A.7.5) Ribokinase (EC 2.7.1.15) Ribose 5-phosphate isomerase A (EC 5.3.1.6) Ribose 5-phosphate isomerase B (EC 5.3.1.6) Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1) Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1) Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) Ribose operon repressor Ribose/xylose/arabinose/galactoside ABC-type transport systems, ATP-binding protein (EC 3.6.3.17) Ribose/xylose/arabinose/galactoside ABC-type transport systems, periplasmic sugar binding protein Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease component 1 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease component 2 Deoxyribose_and_Deoxynucleoside_Catabolism Deoxyribonucleoside regulator DeoR (transcriptional repressor) Deoxyribose operon repressor, DeoR family Deoxyribose-phosphate aldolase (EC 4.1.2.4) Nucleoside permease NupC Phosphopentomutase (EC 5.4.2.7) Predicted nucleoside ABC transporter, ATP-binding component Predicted nucleoside ABC transporter, permease 1 component Predicted nucleoside ABC transporter, permease 2 component Predicted nucleoside ABC transporter, substrate-binding component Purine nucleoside phosphorylase (EC 2.4.2.1) Putative deoxyribonuclease YjjV Putative deoxyribose-specific ABC transporter, ATP-binding protein Putative deoxyribose-specific ABC transporter, permease protein Pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) Ribokinase (EC 2.7.1.15) Thymidine phosphorylase (EC 2.4.2.4) Fructose_utilization 1-phosphofructokinase (EC 2.7.1.56) Beta-fructosidase BfrA Fructokinase (EC 2.7.1.4) Fructokinase (EC 2.7.1.4) Fructose ABC transporter, ATP-binding component FrcA Fructose ABC transporter, permease component FrcC Fructose ABC transporter, substrate-binding component FrcB Fructose repressor FruR, LacI family Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) PTS system, fructose-specific IIA component (EC 2.7.1.69) PTS system, fructose-specific IIB component (EC 2.7.1.69) PTS system, fructose-specific IIC component (EC 2.7.1.69) Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Phosphotransferase system, phosphocarrier protein HPr Predicted regulator of fructose utilization, DeoR family Transaldolase (EC 2.2.1.2) Transcriptional regulator FrcR for fructose utilization, ROK family Transcriptional repressor of the fructose operon, DeoR family Hexose_Phosphate_Uptake_System Hexose phosphate transport protein UhpT Hexose phosphate uptake regulatory protein UhpC Homolog of fucose/glucose/galactose permeases Sensor histidine protein kinase UhpB, glucose-6-phosphate specific (EC 2.7.13.3) Transcriptional regulatory protein UhpA L-Arabinose_utilization 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) Alpha-L-arabinofuranosidase II precursor (EC 3.2.1.55) Alpha-N-arabinofuranosidase (EC 3.2.1.55) Alpha-N-arabinofuranosidase 2 (EC 3.2.1.55) Alpha-N-arabinofuranosidase II (EC 3.2.1.55) Alpha-arabinosides ABC transport system, permease protein 1 Alpha-arabinosides ABC transport system, permease protein 2 Alpha-arabinosides ABC transport system, substrate-binding protein Alternative L-arabinose isomerase (EC 5.3.1.4) Arabinan endo-1,5-alpha-L-arabinosidase (EC 3.2.1.99) Arabinose operon protein AraL Arabinose operon regulatory protein Arabinose-proton symporter Arabinose-regulated TonB-dependent outer membrane receptor Hypothetical glycoside hydrolase, family 43, similar to arabinosidase Hypothetical phosphoglucomutase family hydrolase in arabinose utilization cluster L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) L-arabinolactonase (EC 3.1.1.15) L-arabinose 1-dehydrogenase (EC 1.1.1.46) L-arabinose isomerase (EC 5.3.1.4) L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2) L-arabinose transport system permease protein (TC 3.A.1.2.2) L-arabinose-binding periplasmic protein precursor AraF (TC 3.A.1.2.2) L-arabinose-specific 1-epimerase (mutarotase) L-arabonate dehydratase (EC 4.2.1.25) L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) Possible GPH family transporter (TC 2.A.2) for arabinosides Predicted L-arabinose ABC transport system, ATP-binding protein Predicted L-arabinose ABC transport system, periplasmic arabinose-binding protein Predicted L-arabinose ABC transport system, permease protein 1 Predicted L-arabinose ABC transport system, permease protein 2 Predicted L-arabinose isomerase (EC 5.3.1.4) Predicted arabinose ABC transporter, permease protein 1 Predicted arabinose ABC transporter, permease protein 2 Predicted arabinose ABC transporter, substrate binding protein Predicted glycerol-1-phosphate dehydrogenase, arabinose operon Protein AraJ precursor Putative oxidoreductase in arabinose utilization cluster Ribulokinase (EC 2.7.1.16) Transcriptional regulator of the arabinose operon in Shewanella, GntR family Transcriptional repressor of arabinoside utilization operon, GntR family alternative Ribulokinase (EC 2.7.1.16) L-ascorbate_utilization_(and_related_gene_clusters) 3-dehydro-L-gulonate 2-dehydrogenase (EC 1.1.1.130) 3-keto-L-gulonate 6-phosphate decarboxylase 3-keto-L-gulonate 6-phosphate decarboxylase homolog 3-keto-L-gulonate-6-phosphate decarboxylase UlaD (EC 4.1.1.85) (L-ascorbate utilization protein D) Ascorbate utilization transcriptional regulator UlaR, HTH-type Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-) Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69) Ascorbate-specific PTS system, EIIC component L-ribulose-5-phosphate 3-epimerase UlaE (EC 5.1.3.22) (L-ascorbate utilization protein E) L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) L-ribulose-5-phosphate 4-epimerase UlaF (EC 5.1.3.4) (L-ascorbate utilization protein F) L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-) L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-) homolog L-xylulose/3-keto-L-gulonate kinase (EC 2.7.1.-) Probable L-ascorbate-6-phosphate lactonase UlaG (EC 3.1.1.-) (L-ascorbate utilization protein G) Putative 2-keto-3-deoxygluconate kinase (EC 2.7.1.45) Transcriptional antiterminator with PTS regulation domain, SPy0181 ortholog L-fucose_utilization Alpha-L-fucosidase (EC 3.2.1.51) Fucose permease L-fucose isomerase (EC 5.3.1.25) L-fucose mutarotase L-fucose operon activator L-fuculokinase (EC 2.7.1.51) L-fuculose phosphate aldolase (EC 4.1.2.17) Lactaldehyde dehydrogenase involved in fucose or rhamnose utilization (EC 1.2.1.22) Lactaldehyde reductase (EC 1.1.1.77) Possible alternative L-fucose mutarotase Possible fucose ABC transporter, substrate-binding component Predicted L-fucose-specific phosphotransferase system, EIIA component Predicted L-fucose-specific phosphotransferase system, EIIB component Predicted L-fucose-specific phosphotransferase system, EIIC component Predicted L-fucose-specific phosphotransferase system, EIID component Transcriptional regulator of fucose utilization, GntR family L-fucose_utilization_temp 2,4-diketo-3-deoxy-L-fuconate hydrolase 2-keto-3-deoxy-L-fuconate dehydrogenase Alpha-L-fucosidase (EC 3.2.1.51) Fucose permease L-fuco-beta-pyranose dehydrogenase L-fuconate dehydratase (EC 4.2.1.68) L-fuconolactone hydrolase Possible alternative L-fucose mutarotase dehydrogenase clustered with L-fuconate utilization genes L-rhamnose_utilization Aldehyde dehydrogenase A (EC 1.2.1.22) Alfa-L-rhamnosidase (EC 3.2.1.40) Alternative L-rhamnose isomerase (EC 5.3.1.14) Glycoside hydrolase family 2, sugar binding L-2,4-diketo-3-deoxyrhamnonate hydrolase L-2-keto-3-deoxyrhamnonate (l-KDR) aldolase L-2-keto-3-deoxyrhamnonate-(4)-dehydrogenase L-lactate dehydrogenase (EC 1.1.2.3) L-rhamno-gamma-lactonase (EC 3.1.1.65) L-rhamnonate dehydratase (EC 4.2.1.90) L-rhamnose isomerase (EC 5.3.1.14) L-rhamnose isomerase (EC 5.3.1.14) L-rhamnose mutarotase L-rhamnose operon regulatory protein RhaS L-rhamnose operon transcriptional activator RhaR L-rhamnose-1-dehydrogenase ( EC 1.1.1.173) L-rhamnose-proton symporter Lactaldehyde dehydrogenase involved in fucose or rhamnose utilization (EC 1.2.1.22) Lactaldehyde reductase (EC 1.1.1.77) Pedicted L-rhamnose permease, NCS1 Family Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF Predicted L-rhamnose ABC transporter, ATP-binding component Predicted L-rhamnose ABC transporter, substrate-binding component Predicted L-rhamnose ABC transporter, transmembrane component 1 Predicted L-rhamnose ABC transporter, transmembrane component 2 Predicted L-rhamnose mutarotase Predicted L-rhamnose permease RhaY Predicted alpha-L-rhamnosidase Predicted lactaldehyde dehydrogenase (EC 1.2.1.22) Predicted regulator of rhamnose oligosacchoride utilization, DeoR family Predicted rhamnogalacturonan lyase in rhamnose utilization cluster Predicted rhamnogalacturonide-specific TRAP-type transporter, large transmembrane component RhiC Predicted rhamnogalacturonide-specific TRAP-type transporter, small transmembrane component RhiB Predicted rhamnogalacturonide-specific TRAP-type transporter, substrate-binding component RhiA Predicted rhamnose oligosaccharide ABC transporter, ATP-binding component 1 Predicted rhamnose oligosaccharide ABC transport system, permease component Predicted rhamnose oligosaccharide ABC transport system, permease component 2 Predicted rhamnose oligosaccharide ABC transport system, substrate-binding component Predicted rhamnose oligosaccharide ABC transporter, ATP-binding component 2 Predicted rhamnose oligosaccharide ABC transporter, permease component 1 Predicted rhamnose oligosaccharide ABC transporter, permease component 2 Predicted rhamnose oligosaccharide ABC transporter, substrate-binding component Predicted rhamnulose-1-phosphate aldolase (EC 4.1.2.19) Putative beta-glucuronidase Putative unsaturated glucuronyl hydrolase Rhamnogalacturonide transporter RhiT Rhamnogalacturonides degradation protein RhiN Rhamnulokinase (EC 2.7.1.5) Rhamnulokinase RhaK in alpha-proteobacteria (EC 2.7.1.5) Rhamnulose-1-phosphate aldolase (EC 4.1.2.19) Transcriptional regulator of rhamnose utilization, AraC family Transcriptional regulator of rhamnose utilization, DeoR family Transcriptional regulator of rhamnose utilization, GntR family Transcriptional regulator of rhamnose utilization, LacI family Transcriptional regulator of rhamnose utilization, LysR family rhamnogalacturonan acetylesterase Mannose_Metabolism Activator of the mannose operon (transcriptional antiterminator), BglG family Alpha-1,2-mannosidase Alpha-mannosidase (EC 3.2.1.24) Beta-mannan and fructose induced hypothetical ABC transporter, ATP-binding protein 1 Beta-mannan and fructose induced hypothetical ABC transporter, ATP-binding protein 2 Beta-mannan and fructose induced hypothetical ABC transporter, periplasmic oligopeptide-binding protein Beta-mannan and fructose induced hypothetical ABC transporter, permease protein 1 Beta-mannan and fructose induced hypothetical ABC transporter, permease protein 2 Beta-mannosidase (EC 3.2.1.25) Beta-mannosidase Man2 D-mannose isomerase (EC 5.3.1.7) Endo-1,4-beta-mannosidase Endo-alpha-mannosidase Endo-mannanase (EC 3.2.1.78) Endoglucanase (EC 3.2.1.4) Fructokinase in mannoside utilization gene cluster (EC 2.7.1.4) GDP-mannose mannosyl hydrolase (EC 3.6.1.-) Hexokinase (EC 2.7.1.1) Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13 ) Mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) Mannose-6-phosphate isomerase (EC 5.3.1.8) Mannose-6-phosphate isomerase, class I (EC 5.3.1.8) Mannoside ABC transport system, ATP-binding protein 1 Mannoside ABC transport system, ATP-binding protein 2 Mannoside ABC transport system, permease protein 1 Mannoside ABC transport system, permease protein 2 Mannoside ABC transport system, sugar-binding protein Mannosides-regulated TonB-dependent outer membrane receptor PTS system, mannose-specific IIA component (EC 2.7.1.69) PTS system, mannose-specific IIB component (EC 2.7.1.69) PTS system, mannose-specific IIC component (EC 2.7.1.69) PTS system, mannose-specific IID component (EC 2.7.1.69) Phosphomannomutase (EC 5.4.2.8) Predicted alpha-mannoside ABC transporter, permease protein 1 Predicted alpha-mannoside ABC transporter, permease protein 2 Predicted alpha-mannoside ABC transporter, substrate binding protein Predicted dehydrogenase in CelR regulon, COG0673 Predicted glycosylase TM1225 Predicted glycosylase, COG2152 Predicted mannose transporter, GGP family Predicted regulator of alpha-mannoside utilization, LacI family Predicted regulator of mannoside utilization, LacI family Predicted sodium-dependent mannose transporter Putative regulator of the mannose operon, ManO Transcriptional regulator of mannoside utilization, LacI family Transcriptional regulator of mannoside utilization, variant 2, LacI family Xylose_utilization 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) Acetyl xylan esterase (EC 3.1.1.41) Acetyl xylan esterase XylU (EC 3.1.1.41) Alpha-xylosidase (EC 3.2.1.-) Beta-xylosidase (EC 3.2.1.37) D-xylose 1-dehydrogenase (EC 1.1.1.175) D-xylose proton-symporter XylE D-xylose proton-symporter XylT D-xylose transport ATP-binding protein XylG D-xylose-specific 1-epimerase (mutarotase) Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8) Endo-1,4-beta-xylanase B ( EC 3.2.1.8 ) Endo-1,4-beta-xylanase C precursor (EC 3.2.1.8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) Novel Xylose regulator from LacI family Phosphotransferase system for xylose-containing disaccharide, EIIA component Phosphotransferase system for xylose-containing disaccharide, EIIB component Phosphotransferase system for xylose-containing disaccharide, EIIC component Phosphotransferase system for xylose-containing disaccharide, EIID component Possible alpha-xyloside ABC transporter, ATP-binding component Possible alpha-xyloside ABC transporter, permease component Possible alpha-xyloside ABC transporter, substrate-binding component Predicted xylose oligosaccharide ABC transporter, substrate-binding component Putative alpha-xylosidase (EC 3.2.1.-) Putative xylulose kinase (EC 2.7.1.17) Xylanase Xylonate dehydratase (EC 4.2.1.82) Xylonolactonase (EC 3.1.1.68) Xylose ABC transporter, ATP-binding component Xylose ABC transporter, periplasmic xylose-binding protein XylF Xylose ABC transporter, permease component Xylose ABC transporter, permease protein XylH Xylose ABC transporter, substrate-binding component Xylose activator XylR (AraC family) Xylose isomerase (EC 5.3.1.5) Xylose oligosaccharides ABC transporter, ATP-binding protein 1 Xylose oligosaccharides ABC transporter, ATP-binding protein 2 Xylose oligosaccharides ABC transporter, permease protein 1 Xylose oligosaccharides ABC transporter, permease protein 2 Xylose oligosaccharides ABC transporter, sugar-binding protein Xylose-responsive transcription regulator, ROK family Xyloside transporter XynT Xylulose kinase (EC 2.7.1.17) predicted 2-keto-3-deoxyxylonate dehydratase predicted xylose isomerase 02 One-carbon Metabolism Formaldehyde_assimilation:_Ribulose_monophosphate_pathway 6-phospho-3-hexuloisomerase D-arabino-3-hexulose 6-phosphate formaldehyde lyase Formaldehyde activating enzyme Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG) Putative pentose isomerase Transcriptional regulator HxlR, formaldehyde assimilation related to 6-phospho-3-hexuloisomerase Methanogenesis CoB--CoM heterodisulfide reductase subunit A (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit B (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit C (EC 1.8.98.1) F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase (EC 1.5.99.11) F420-dependent methylenetetrahydromethanopterin dehydrogenase (EC 1.5.99.9) Formylmethanofuran dehydrogenase (molybdenum) operon gene E Formylmethanofuran dehydrogenase (molybdenum) operon gene F (polyferredoxin) Formylmethanofuran dehydrogenase (molybdenum) operon gene G Formylmethanofuran dehydrogenase (molybdenum) subunit B (EC 1.2.99.5) Formylmethanofuran dehydrogenase (molybdenum) subunit C (EC 1.2.99.5) Formylmethanofuran dehydrogenase (molybdenum) subunit D (EC 1.2.99.5) Formylmethanofuran dehydrogenase (tungsten) operon gene F (polyferredoxin) Formylmethanofuran dehydrogenase (tungsten) operon gene G Formylmethanofuran dehydrogenase (tungsten) operon gene H Formylmethanofuran dehydrogenase (tungsten) subunit B (EC 1.2.99.5) Formylmethanofuran dehydrogenase (tungsten) subunit C (EC 1.2.99.5) Formylmethanofuran dehydrogenase (tungsten) subunit D (EC 1.2.99.5) Formylmethanofuran dehydrogenase subunit A (EC 1.2.99.5) Formylmethanofuran dehydrogenase subunit B (EC 1.2.99.5) Formylmethanofuran dehydrogenase subunit C (EC 1.2.99.5) Formylmethanofuran dehydrogenase subunit D (EC 1.2.99.5) Formylmethanofuran--tetrahydromethanopterin N-formyltransferase (EC 2.3.1.101) Methyl coenzyme M reductase I alpha subunit (EC 2.8.4.1) Methyl coenzyme M reductase I beta subunit (EC 2.8.4.1) Methyl coenzyme M reductase I gamma subunit (EC 2.8.4.1) Methyl coenzyme M reductase II alpha subunit (EC 2.8.4.1) Methyl coenzyme M reductase II beta subunit (EC 2.8.4.1) Methyl coenzyme M reductase II gamma subunit (EC 2.8.4.1) Methyl coenzyme M reductase alpha subunit (EC 2.8.4.1) Methyl coenzyme M reductase associated protein Methyl coenzyme M reductase beta subunit (EC 2.8.4.1) Methyl coenzyme M reductase gamma subunit (EC 2.8.4.1) Methyl coenzyme M reductase operon protein C Methyl coenzyme M reductase operon protein D N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (EC 3.5.4.27) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit B (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit C (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit D (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit E (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit F (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit G (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H (EC 2.1.1.86) N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit X Methanogenesis_from_methylated_compounds Dimethylamine methyltransferase corrinoid protein Dimethylamine permease Dimethylamine:corrinoid methyltransferase Methanol methyltransferase corrinoid protein Methanol:corrinoid methyltransferase Methylcobalamin:coenzyme M methyltransferase, methanol-specific Methylcobalamin:coenzyme M methyltransferase, methylamine-specific Methylthiol:coenzyme M methyltransferase Methylthiol:coenzyme M methyltransferase corrinoid protein Monomethylamine methyltransferase corrinoid protein Monomethylamine permease Monomethylamine:corrinoid methyltransferase Trimethylamine methyltransferase corrinoid protein Trimethylamine permease Trimethylamine:corrinoid methyltransferase pyrrolysine-containing One-carbon_metabolism_by_tetrahydropterines 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 5-FCL-like protein, but predicted not to be 5-formyltetrahydrofolate cyclo-ligase (5-FCL) 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) F420-dependent methylenetetrahydromethanopterin dehydrogenase (EC 1.5.99.9) Formate--tetrahydrofolate ligase (EC 6.3.4.3) Formiminotetrahydrofolate cyclodeaminase (EC 4.3.1.4) Formyltetrahydrofolate deformylase (EC 3.5.1.10) Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) Methylene tetrahydromethanopterin dehydrogenase (EC 1.5.99.9) Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (EC 3.5.4.27) Serine-glyoxylate_cycle 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 5-FCL-like protein, but predicted not to be 5-formyltetrahydrofolate cyclo-ligase (5-FCL) 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Acetoacetyl-CoA reductase (EC 1.1.1.36) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Aconitate hydratase (EC 4.2.1.3) Citrate synthase (EC 2.3.3.1) Citrate synthase (si) (EC 2.3.3.1) Enolase (EC 4.2.1.11) Formate--tetrahydrofolate ligase (EC 6.3.4.3) Formiminotetrahydrofolate cyclodeaminase (EC 4.3.1.4) Fumarate hydratase class I, aerobic (EC 4.2.1.2) Fumarate hydratase class I, anaerobic (EC 4.2.1.2) GDSL-like lipase/acylhydrolase Glycerate kinase (EC 2.7.1.31) Isocitrate lyase (EC 4.1.3.1) Malate dehydrogenase (EC 1.1.1.37) Malate synthase-related protein Malyl-CoA lyase (EC 4.1.3.24) Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) Methylene tetrahydromethanopterin dehydrogenase (EC 1.5.99.9) Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Methylmalonyl-CoA mutase (EC 5.4.99.2) N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (EC 3.5.4.27) Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) Phosphoglyceromutase Propionyl-CoA carboxylase beta chain (EC 6.4.1.3) Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3) Putative malate dehydrogenase (EC 1.1.1.37), similar to archaeal MJ1425 Serine hydroxymethyltransferase (EC 2.1.2.1) Serine--glyoxylate aminotransferase (EC 2.6.1.45) Serine--pyruvate aminotransferase (EC 2.6.1.51) Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) crotonyl-CoA reductase cytosolic long-chain acyl-CoA thioester hydrolase family protein decarboxylase isobutyryl-CoA dehydrogenase low-specificity D-threonine aldolase polyhydroxyalkanoate synthesis repressor PhaR putative glycerate kinase putative isobutyryl-CoA mutase, chain B 02 Organic acids 2-methylcitrate_to_2-methylaconitate_metabolism_cluster 2-Methylcitrate dehydratase AcnD 2-methylaconitate racemase Alpha-acetolactate_operon Acetolactate synthase, catabolic (EC 2.2.1.6) Alpha-acetolactate decarboxylase (EC 4.1.1.5) Glycerate_metabolism 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) D-glycerate 2-kinase (EC 2.7.1.-) D-glycerate 3-kinase (EC 2.7.1.31), plant type D-glycerate transporter (predicted) Glycerate kinase (EC 2.7.1.31) Glyoxylate carboligase (EC 4.1.1.47) Hydroxypyruvate isomerase (EC 5.3.1.22) Hydroxypyruvate reductase (EC 1.1.1.81) Pyruvate kinase (EC 2.7.1.40) Serine--glyoxylate aminotransferase (EC 2.6.1.45) Tartrate decarboxylase (EC 4.1.1.73) Isobutyryl-CoA_to_Propionyl-CoA_Module 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35) 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) Lactate_utilization D-Lactate dehydrogenase (EC 1.1.2.5) L-lactate dehydrogenase (EC 1.1.2.3) L-lactate permease Lactate-responsive regulator LldR in Actinobacteria, GntR family Lactate-responsive regulator LldR in Betaproteobacteria, LysR family Lactate-responsive regulator LldR in Enterobacteria, GntR family Lactate-responsive regulator LldR in Firmicutes, GntR family Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF Predicted L-lactate dehydrogenase, hypothetical protein subunit SO1518 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG Predicted Lactate-responsive regulator, IclR family Predicted Lactate-responsive regulator, LysR family Predicted lactate-responsive transcriptional regulator of ykgEFG LDH gene cluster, LysR-type Malonate_decarboxylase Malonate decarboxylase alpha subunit Malonate decarboxylase beta subunit Malonate decarboxylase delta subunit Malonate decarboxylase gamma subunit Malonate transporter, MadL subunit Malonate transporter, MadM subunit Malonate utilization transcriptional regulator Malonyl CoA acyl carrier protein transacylase (EC 2.3.1.39) Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) Triphosphoribosyl-dephospho-CoA synthetase (EC 2.7.8.25) Methylcitrate_cycle 2-methylcitrate dehydratase (EC 4.2.1.79) 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) 2-methylcitrate synthase (EC 2.3.3.5) 2-methylisocitrate dehydratase (EC 4.2.1.99) Methylisocitrate lyase (EC 4.1.3.30) Propionate catabolism operon regulatory protein PrpR Propionate catabolism operon transcriptional regulator of GntR family [predicted] Propionate--CoA ligase (EC 6.2.1.17) PrpF protein involved in 2-methylcitrate cycle Propionate-CoA_to_Succinate_Module 2-methylcitrate dehydratase (EC 4.2.1.79) 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) 2-methylcitrate synthase (EC 2.3.3.5) 2-methylisocitrate dehydratase (EC 4.2.1.99) Aconitate hydratase (EC 4.2.1.3) Aconitate hydratase 2 (EC 4.2.1.3) Methylisocitrate lyase (EC 4.1.3.30) Propionate catabolism operon transcriptional regulator of GntR family [predicted] Propionate--CoA ligase (EC 6.2.1.17) PrpF protein involved in 2-methylcitrate cycle Propionyl-CoA_to_Succinyl-CoA_Module B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) Biotin carboxyl carrier protein of Propionyl-CoA carboxylase Biotin carboxylase of Propionyl-CoA carboxylase (EC 6.3.4.14) Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) Methylmalonyl-CoA epimerase (EC 5.1.99.1) Methylmalonyl-CoA mutase (EC 5.4.99.2) Na+/H+-dicarboxylate symporters Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3) Tricarballylate_Utilization TcuA: flavoprotein used to oxidize tricarballylate to cis-aconitate TcuB: works with TcuA to oxidize tricarballylate to cis-aconitate TcuC: integral membrane protein used to transport tricarballylate across the cell membrane TcuR: regulates tcuABC genes used in utilization of tricarballylate 02 Polysaccharides Alpha-Amylase_locus_in_Streptocococcus Cyclomaltodextrin glucanotransferase (EC 2.4.1.19) Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE Transposase (maltose area) putative esterase Cellulosome 1,4-alpha-glucan branching enzyme (EC 2.4.1.18) Alpha-amylase (Neopullulanase) SusA (EC 3.2.1.135) Alpha-amylase SusG (EC 3.2.1.1) Alpha-glucosidase SusB (EC 3.2.1.20) Clostridium cellulosome enzyme, dockerin type I precursor Outer membrane protein SusE Outer membrane protein SusF Regulatory protein SusR SusC, outer membrane protein involved in starch binding SusD, outer membrane protein Glycogen_metabolism 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25) Alpha-glucosidase, family 31 of glycosyl hydrolases, COG1501 Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) Glycogen biosynthesis protein GlgD, glucose-1-phosphate adenylyltransferase family Glycogen branching enzyme, GH-57-type, archaeal (EC 2.4.1.18) Glycogen debranching enzyme (EC 3.2.1.-) Glycogen phosphorylase (EC 2.4.1.1) Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) Maltodextrin phosphorylase (EC 2.4.1.1) Predicted glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21), Actinobacterial type Putative glycogen debranching enzyme, archaeal type, TIGR01561 Unknown_carbohydrate_utilization_containing_Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase (EC 4.1.2.13) Phosphotransferase system HPr enzyme in cluster with fructose-bisphosphate aldolase Putative carbohydrate PTS system, IIA component (EC 2.7.1.69) Putative carbohydrate PTS system, IIB component (EC 2.7.1.69) Putative carbohydrate PTS system, IIC component (EC 2.7.1.69) Putative carbohydrate kinase in cluster with fructose-bisphosphate aldolase Putative transcriptional regulator of unknown carbohydrate utilization cluster, GntR family Xyloglucan_Utilization Extracellular endo-1,4-glucanase Glucose oligosaccharide ABC transport system, ATP-binding protein 1 Glucose oligosaccharide ABC transport system, ATP-binding protein 2 Glucose oligosaccharide ABC transport system, permease protein 1 Glucose oligosaccharide ABC transport system, permease protein 2 Glucose oligosaccharide ABC transport system, sugar-binding protein Predicted glucose oligosaccharide utilization regulator, LacI family Putative alpha-glucosidase Putative sugar isomerase Regulator of trehalose utilization TreR, ROK family Trehalose synthase, nucleoside diphosphate glucose dependent 02 Sugar alcohols Erythritol_utilization Erythritol kinase EryA (EC 2.7.1.27) Erythritol phosphate dehydrogenase EryB Erythritol transcriptional regulator EryD Possible D-erythrulose 4-phosphate dehydrogenase EryC (EC 1.1.1.-) Predicted erythritol ABC transporter 1, ATP-binding component 1 Predicted erythritol ABC transporter 1, ATP-binding component 2 Predicted erythritol ABC transporter 1, permease component 1 Predicted erythritol ABC transporter 1, permease component 2 Predicted erythritol ABC transporter 1, substrate-binding component Predicted erythritol ABC transporter 2, ATP-binding component Predicted erythritol ABC transporter 2, hypothetical lipoprotein Predicted erythritol ABC transporter 2, permease component Predicted erythritol ABC transporter 2, substrate-binding component Ethanolamine_utilization ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17), ethanolamine utilization Acetaldehyde dehydrogenase, ethanolamine utilization cluster Acetate kinase (EC 2.7.2.1) Ethanolamine ammonia-lyase heavy chain (EC 4.3.1.7) Ethanolamine ammonia-lyase light chain (EC 4.3.1.7) Ethanolamine operon regulatory protein Ethanolamine permease Ethanolamine sensory transduction histidine kinase Ethanolamine two-component response regulator Ethanolamine utilization polyhedral-body-like protein EutK Ethanolamine utilization polyhedral-body-like protein EutL Ethanolamine utilization polyhedral-body-like protein EutM Ethanolamine utilization polyhedral-body-like protein EutN Ethanolamine utilization polyhedral-body-like protein EutS Ethanolamine utilization protein EutA Ethanolamine utilization protein EutG Ethanolamine utilization protein EutJ Ethanolamine utilization protein EutP Ethanolamine utilization protein EutQ Ethanolamine utilization protein similar to PduA/PduJ Ethanolamine utilization protein similar to PduL Ethanolamine utilization protein similar to PduT Ethanolamine utilization protein similar to PduU Ethanolamine utilization protein similar to PduV Phosphate acetyltransferase (EC 2.3.1.8) Phosphate acetyltransferase (EC 2.3.1.8), ethanolamine utilization-specific Protein clustered with ethanolamine utilization Glycerol_and_Glycerol-3-phosphate_Uptake_and_Utilization Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Alpha-glycerophosphate oxidase (EC 1.1.3.21) Anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) Anaerobic glycerol-3-phosphate dehydrogenase subunit B (EC 1.1.5.3) GlpG protein (membrane protein of glp regulon) Glycerol kinase (EC 2.7.1.30) Glycerol uptake facilitator protein Glycerol uptake operon antiterminator regulatory protein Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3) Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3) Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3) Glycerol-3-phosphate ABC transporter, permease protein UgpE (TC 3.A.1.1.3) Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) Glycerol-3-phosphate regulon repressor, DeoR family Glycerol-3-phosphate transporter Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) Glycerophosphoryl diester phosphodiesterase, periplasmic (EC 3.1.4.46) NADH peroxidase (EC 1.11.1.1) Probable glycerol transport protein Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1) Glycerol_fermenation_to_1,3-propanediol 1,3-propanediol dehydrogenase (EC 1.1.1.202) Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) Glycerol dehydratase large subunit (EC 4.2.1.30) Glycerol dehydratase medium subunit (EC 4.2.1.30) Glycerol dehydratase reactivation factor large subunit Glycerol dehydratase reactivation factor small subunit Glycerol dehydratase small subunit (EC 4.2.1.30) Glycerol uptake facilitator protein Inositol_catabolism 5-deoxy-glucuronate isomerase (EC 5.3.1.-) 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase [form 2] (EC 4.1.2.29) 5-keto-2-deoxygluconokinase (EC 2.7.1.92) Epi-inositol hydrolase (EC 3.7.1.-) Fe-containing alcohol dehydrogenase Glyceraldehyde-3-phosphate ketol-isomerase (EC 5.3.1.1) Inositol oxygenase (EC 1.13.99.1) Inositol transport system ATP-binding protein Inositol transport system permease protein Inositol transport system sugar-binding protein Inosose dehydratase (EC 4.2.1.44) Inosose isomerase (EC 5.3.99.-) Major myo-inositol transporter IolT Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) Minor myo-inositol transporter IolF Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) Myo-inositol 2-dehydrogenase 2 (EC 1.1.1.18) Predicted transcriptional regulator of the myo-inositol catabolic operon Sodium/myo-inositol cotransporter Transcriptional repressor of the myo-inositol catabolic operon DeoR family uncharacterized domain Mannitol_Utilization Fructokinase (EC 2.7.1.4) Fructokinase in mannitol utilization gene cluster (EC 2.7.1.4) HPr kinase/phosphorylase (EC 2.7.1.-) (EC 2.7.4.-) Hydrolase in polyol utilization gene cluster, haloacid dehalogenase-like family Mannitol operon activator, BglG family Mannitol operon repressor Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) Multiple polyol-specific dehydrogenase (EC 1.1.1.-) PTS system, mannitol-specific IIA component (EC 2.7.1.69) PTS system, mannitol-specific IIB component (EC 2.7.1.69) PTS system, mannitol-specific IIC component (EC 2.7.1.69) PTS system, mannitol-specific cryptic IIA component (EC 2.7.1.69) PTS system, mannitol-specific cryptic IIB component (EC 2.7.1.69) PTS system, mannitol-specific cryptic IIC component (EC 2.7.1.69) Phosphocarrier protein of PTS system Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Predicted mannitol permease Transcriptional regulator of mannitol utilization, DeoR family protein Propanediol_utilization CoA-acylating propionaldehyde dehydrogenase Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) Cob(II)alamin reductase Cob(III)alamin reductase Phosphate acetyltransferase (EC 2.3.1.8) Propanediol dehydratase large subunit (EC 4.2.1.28) Propanediol dehydratase medium subunit (EC 4.2.1.28) Propanediol dehydratase reactivation factor large subunit Propanediol dehydratase reactivation factor small subunit Propanediol dehydratase small subunit (EC 4.2.1.28) Propanediol diffusion facilitator Propanediol utilization polyhedral body protein PduA Propanediol utilization polyhedral body protein PduB Propanediol utilization polyhedral body protein PduJ Propanediol utilization polyhedral body protein PduK Propanediol utilization polyhedral body protein PduN Propanediol utilization polyhedral body protein PduT Propanediol utilization polyhedral body protein PduU Propanediol utilization protein PduL Propanediol utilization protein PduM Propanediol utilization protein PduV Propanediol utilization transcriptional activator Propionate kinase, propanediol utilization (EC 2.7.2.1) Putative iron-containing NADPH-dependent propanol dehydrogenase Threonine kinase in B12 biosynthesis 02 Conserved_cluster_around_inner_membrane_protein_gene_yghQ,_probably_involved_in_polysaccharide_biosynthesis Conserved ATP-binding protein YghS Conserved hypothetical TPR repeat protein, clustered with yghQ Conserved protein YghR, with nucleoside triphosphate hydrolase domain Conserved protein YghT, with nucleoside triphosphate hydrolase domain Inner membrane protein YghQ, probably involved in polysaccharide biosynthesis Permease Ygh-P1, YjgP/YjgQ family Permease Ygh-P2, YjgP/YjgQ family Transcriptional regulator, YtfJ-family Lacto-N-Biose_I_and_Galacto-N-Biose_Metabolic_Pathway Lacto-N-biose phosphorylase (EC 2.4.1.211) N-acetylhexosamine 1-kinase Predicted galacto-N-biose-/lacto-N-biose I ABC transporter, periplasmic substrate-binding protein Predicted galacto-N-biose-/lacto-N-biose I ABC transporter, permease component 1 Predicted galacto-N-biose-/lacto-N-biose I ABC transporter, permease component 2 UDP-glucose 4-epimerase (EC 5.1.3.2) UDP-glucose hexose 1-phosphate uridylyltransferase Sugar_utilization_in_Thermotogales 1-phosphofructokinase (EC 2.7.1.56) 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 4-alpha-glucanotransferase MgtA (EC 2.4.1.25) 6-phospho-beta-glucosidase BglT (EC 3. 2.1.86) 6-phosphofructokinase (EC 2.7.1.11) 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type Acetyl xylan esterase (EC 3.1.1.41) Acetyl xylan esterase XylU (EC 3.1.1.41) Alcohol dehydrogenase, zinc-containing Alpha-1,4-amylase Alpha-1,4-digalacturonate ABC transporter, permease protein 1 Alpha-1,4-digalacturonate ABC transporter, permease protein 2 Alpha-1,4-digalacturonate ABC transporter, substrate-binding protein Alpha-1,6-pullulanase Alpha-N-arabinofuranosidase (EC 3.2.1.55) Alpha-N-arabinofuranosidase II (EC 3.2.1.55) Alpha-galactosidase (EC 3.2.1.22) Alpha-glucuronidase (EC 3.2.1.139) Alpha-mannosidase (EC 3.2.1.24) Alpha-mannosidase-related protein, family 38 Alternative L-rhamnose isomerase (EC 5.3.1.14) Arabinogalactan endo-1,4-beta-galactosidase (EC 3.2.1.89) Beta-fructosidase BfrA Beta-galactosidase (EC 3.2.1.23) Beta-galactosidase (EC 3.2.1.23), LacA family Beta-galactosidase (EC 3.2.1.23), LacZ family Beta-glucosidase (EC 3.2.1.21) Beta-glucosidase A (EC 3.2.1.21) Beta-glucoside ABC transport system, ATP-binding protein 1 Beta-glucoside ABC transport system, ATP-binding protein 2 Beta-glucoside ABC transport system, permease protein 1 Beta-glucoside ABC transport system, permease protein 2 Beta-glucoside ABC transport system, sugar-binding protein Beta-hexosaminidase (EC 3.2.1.52) Beta-mannan and fructose induced hypothetical ABC transporter, ATP-binding protein 1 Beta-mannan and fructose induced hypothetical ABC transporter, ATP-binding protein 2 Beta-mannan and fructose induced hypothetical ABC transporter, periplasmic oligopeptide-binding protein Beta-mannan and fructose induced hypothetical ABC transporter, permease protein 1 Beta-mannan and fructose induced hypothetical ABC transporter, permease protein 2 Beta-mannosidase Man2 Beta-xylosidase (EC 3.2.1.37) Carbohydrate-binding, CenC domain protein Cellobiose phosphorylase (EC 2.4.1.-) Cellobiose-responsive regulator of beta-glucosides utilization, ROK family Cytoplasmic endo-1,4-beta-glucanase (EC 3.2.1.4) D-arabitol dehydrogenase (EC 1.1.1.250) D-glycerate 2-kinase (EC 2.7.1.-) D-mannonate oxidoreductase (EC 1.1.1.57) Endo-1,4-beta-mannosidase Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8) Endo-1,4-beta-xylanase B ( EC 3.2.1.8 ) Endo-1,4-beta-xylanase C precursor (EC 3.2.1.8) Endo-mannanase (EC 3.2.1.78) Endoglucanase (EC 3.2.1.4) Enolase (EC 4.2.1.11) Extracellular alpha-amylase precursor Extracellular endo-1,4-beta-glucanase (EC 3.2.1.4) Extracellular endo-1,4-glucanase Fructokinase (EC 2.7.1.4) Fructose-bisphosphate aldolase class II (EC 4.1.2.13) Galactokinase (EC 2.7.1.6) Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10) Glucokinase (EC 2.7.1.2) Gluconokinase (EC 2.7.1.12) Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) Glucose ABC transporter, ATP-binding component Glucose ABC transporter, permease component Glucose ABC transporter, substrate-binding component Glucose oligosaccharide ABC transport system, ATP-binding protein 1 Glucose oligosaccharide ABC transport system, ATP-binding protein 2 Glucose oligosaccharide ABC transport system, permease protein 1 Glucose oligosaccharide ABC transport system, permease protein 2 Glucose oligosaccharide ABC transport system, sugar-binding protein Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Glucose-6-phosphate isomerase (EC 5.3.1.9) Glycerol kinase (EC 2.7.1.30) Glycerol uptake facilitator protein Glycerol uptake operon antiterminator regulatory protein Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3) Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3) Glycerol-3-phosphate ABC transporter, permease protein UgpE (TC 3.A.1.1.3) Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Glycoside hydrolase family 2, sugar binding Glycosyl transferase group 1 Glycosyl transferase, family 2 Hypothetical protein TM0026, BglR regulon Hypothetical protein TM0950 Hypothetical protein, DUF192 family Hypothetical protein, no COGs Hypothetical sugar ABC transporter TM0460, substrate-binding protein Hypothetical sugar ABC transporter TM1149, permease protein Hypothetical sugar ABC transporter TM1150, substrate-binding protein Hypothetical sugar ABC transporter TM1151, ATP-binding protein Hypothetical sugar ABC transporter, ATP-binding UgtK Hypothetical sugar ABC transporter, membrane protein UgtF Hypothetical sugar ABC transporter, membrane protein UgtG Hypothetical sugar ABC transporter, solute-binding protein UgtE Hypothetical sugar kinase TM0795, PfkB family Inositol-related sugar-phosphate epimerase Intracellular alpha-amylase (EC 3.2.1.1) Iron-containing alcohol dehydrogenase L-arabinose isomerase (EC 5.3.1.4) L-arabinose-specific 1-epimerase (mutarotase) L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) Laminarinase (EC 3.2.1.39) Maltodextrin glucosidase (EC 3.2.1.20) Maltodextrin glycosyltransferase MmtA Maltose oligosaccharide ABC transporter, permease protein MalF1 Maltose oligosaccharide ABC transporter, permease protein MalG1 Maltose oligosaccharide ABC transporter, substrate binding periplasmic protein MalE1 Maltose/maltodextrin ABC transporter 2, permease protein MalF2 Maltose/maltodextrin ABC transporter 2, permease protein MalG2 Maltose/maltodextrin ABC transporter 2, substrate binding periplasmic protein MalE2 Mannonate dehydratase (EC 4.2.1.8) Mannose-6-phosphate isomerase (EC 5.3.1.8) Mannose-responsive regulator of mannose and mannoside utilization, ROK family Mannoside ABC transport system, sugar-binding protein Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) Myo-inositol ABC transporter, ATP-binding protein InoK Myo-inositol ABC transporter, periplasmic sugar-binding protein InoE Myo-inositol ABC transporter, permease protein InoF Myo-inositol ABC transporter, permease protein InoG N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Neopullulanase (EC 3.2.1.135) Novel 5-ketogluconate epimerase Novel D-mannonate dehydrogenase (EC 1.1.1.57) Novel D-mannonate-D-gluconate epimerase Novel D-tagaturonate epimerase Novel N-acetylmannosamine kinase Novel glucosamine kinase, PF00869 family Novel inositol-related kinase, PfkB family (EC 2.7.1.12) PTS system, fructose-specific IIA component (EC 2.7.1.69) PTS system, fructose-specific IIB component (EC 2.7.1.69) PTS system, fructose-specific IIC component (EC 2.7.1.69) Pectate lyase precursor (EC 4.2.2.2) Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Phosphoglycerate dehydrogenase TM0327, putative Phosphoglycerate kinase (EC 2.7.2.3) Phosphoglycerate mutase (EC 5.4.2.1) Phosphotransferase system, phosphocarrier protein HPr Polygalacturonase (EC 3.2.1.15) Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family Predicted L-rhamnose mutarotase Predicted aldo/keto reductase in CelR regulon, COG4989 Predicted alpha-arabinosides ABC transport system, permease protein 1 Predicted alpha-arabinosides ABC transport system, permease protein 2 Predicted alpha-arabinosides ABC transport system, substrate-binding protein Predicted alpha-mannoside ABC transporter, permease protein 1 Predicted alpha-mannoside ABC transporter, permease protein 2 Predicted alpha-mannoside ABC transporter, substrate binding protein Predicted arabinose ABC transporter, permease protein 1 Predicted arabinose isomerase Predicted arabinoside ABC transporter 2, periplasmic sugar-binding protein Predicted arabinoside ABC transporter 2, permease component 2 Predicted beta-glucoside-regulated ABC transport system, permease component 1, COG1175 Predicted beta-glucoside-regulated ABC transport system, permease component 2, COG0395 Predicted beta-glucoside-regulated ABC transport system, sugar binding component, COG1653 Predicted cellobiose ABC transport system, ATP-binding protein 1 Predicted cellobiose ABC transport system, ATP-binding protein 2 Predicted cellobiose ABC transport system, permease protein 1 Predicted cellobiose ABC transport system, permease protein 2 Predicted cellobiose ABC transport system, sugar-binding protein Predicted chitobiose ABC transport system II, permease protein 1 Predicted chitobiose ABC transport system II, permease protein 2 Predicted chitobiose ABC transport system II, sugar-binding protein Predicted chitobiose ABC transport system, permease protein 1 Predicted chitobiose ABC transport system, permease protein 2 Predicted chitobiose ABC transport system, sugar-binding protein Predicted dehydrogenase in CelR regulon, COG0673 Predicted galactoside ABC transporter type II, permease protein 1 Predicted galactoside ABC transporter type II, permease protein 2 Predicted galactoside ABC transporter type II, sugar-binding protein Predicted galactoside ABC transporter, ATP-binding protein 1 Predicted galactoside ABC transporter, ATP-binding protein 2 Predicted galactoside ABC transporter, permease protein 1 Predicted galactoside ABC transporter, permease protein 2 Predicted galactoside ABC transporter, sugar-binding protein Predicted glucose oligosaccharide utilization regulator, LacI family Predicted glycerol-1-phosphate dehydrogenase, arabinose operon Predicted glycosylase TM1225 Predicted glycosylase, COG2152 Predicted inosose dehydrogenase Predicted keto-inosose hydrolase Predicted regulator Pmob_1925 of beta-glucosides utilization, ROK family Predicted regulator of alpha-mannoside utilization, LacI family Predicted regulator of cellobiose and glucan utilization, LacI family Predicted regulator of fructose utilization, DeoR family Predicted regulator of galactoside utilization, LacI family Predicted regulator of glucose and trehalose utilization, ROK family Predicted regulator of rhamnose oligosacchoride utilization, DeoR family Predicted regulator of ribose utilization, LacI family Predicted rhamnose oligosaccharide ABC transporter, ATP-binding component 1 Predicted rhamnose oligosaccharide ABC transporter, ATP-binding component 2 Predicted rhamnose oligosaccharide ABC transporter, permease component 1 Predicted rhamnose oligosaccharide ABC transporter, permease component 2 Predicted rhamnose oligosaccharide ABC transporter, substrate-binding component Predicted sugar catabolic transcriptional regulator UgtR, RpiR family Predicted sugar dehydrogenase TM0325 Predicted trehalose ABC transporter, permease component 1, Archaea-type Predicted trehalose ABC transporter, permease component 2, Archaea-type Predicted trehalose ABC transporter, substrate-binding component, Archaea-type Predicted xylose oligosaccharide ABC transporter, substrate-binding component Pullulanase (EC 3.2.1.41) Putative alpha-glucosidase Putative alpha-glucosidase (EC 3.2.1.-) Putative beta-glucuronidase Putative glycosyl hydrolase of unknown function (DUF1680) Putative methyl oligogalcturonate esterase Putative sugar isomerase Putative unsaturated glucuronyl hydrolase Pyruvate kinase (EC 2.7.1.40) Regulator of chitobiose utilization ChiR, ROK family Regulator of myo-inositol utilization IolR, ROK family Regulator of pectin and galacturonate utilization, GntR family Regulator of trehalose utilization TreR, ROK family Rhamnulokinase (EC 2.7.1.5) Rhamnulose-1-phosphate aldolase (EC 4.1.2.19) Ribokinase (EC 2.7.1.15) Ribose 5-phosphate isomerase B (EC 5.3.1.6) Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1) Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1) Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) Ribulose-phosphate 3-epimerase (EC 5.1.3.1) Thermostable mannitol dehydrogenase Transaldolase (EC 2.2.1.2) Transcriptional repressor of arabinoside utilization operon, GntR family Transketolase (EC 2.2.1.1) Transketolase, C-terminal section (EC 2.2.1.1) Transketolase, N-terminal section (EC 2.2.1.1) Trehalose ABC transporter, permease component 1 Trehalose ABC transporter, permease component 2 Trehalose ABC transporter, substrate-binding component Trehalose synthase, nucleoside diphosphate glucose dependent Triosephosphate isomerase (EC 5.3.1.1) UDP-glucose 4-epimerase (EC 5.1.3.2) Unknown carbohydrate transporter from TRAP family, large transmembrane component UctQ Unknown carbohydrate transporter from TRAP family, small transmembrane component UctM Unknown carbohydrate transporter from TRAP family, substrate-binding component UctP Unknown carbohydrate utilization transcriptional regulator UctR, RpiR family Unknown pentose isomerase TM0951 Unknown pentose kinase TM0952 Uronate isomerase (EC 5.3.1.12) Xylan oligosaccharide ABC transporter, ATP-binding protein 1 Xylan oligosaccharide ABC transporter, substrate-binding component Xylan oligosaccharide ABC transporter, ATP-binding protein 2 Xylan oligosaccharide ABC transporter, permease component 1 Xylan oligosaccharide ABC transporter, permease component 2 Xylose ABC transporter, ATP-binding component Xylose ABC transporter, permease component Xylose ABC transporter, substrate-binding component Xylose isomerase (EC 5.3.1.5) Xylose oligosaccharides ABC transporter, ATP-binding protein 1 Xylose oligosaccharides ABC transporter, ATP-binding protein 2 Xylose oligosaccharides ABC transporter, permease protein 1 Xylose oligosaccharides ABC transporter, permease protein 2 Xylose oligosaccharides ABC transporter, sugar-binding protein Xylose-responsive transcription regulator, ROK family Xylulose kinase (EC 2.7.1.17) alternative Ribulokinase (EC 2.7.1.16) Unknown_carbohydrate_utilization_(_cluster_Ydj_) Aldose 1-epimerase family protein YeaD Hypothetical oxidoreductase YdjG (EC 1.-.-.-) Hypothetical zinc-type alcohol dehydrogenase-like protein YdjJ Inner membrane protein YeaI MltA-interacting protein MipA Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) Putative HTH-type transcriptional regulator YdjF Putative aldolase YdjI Putative oxidoreductase YdjL Putative oxidoreductase YeaE, aldo/keto reductase family Putative transport protein YdjK, MFS superfamily Putative two-component response regulator and GGDEF family protein YeaJ UPF0229 protein YeaH Uncharacterized protein YeaC Uncharacterized protein YeaG Uncharacterized sugar kinase YdjH Unknown_carbohydrate_utilization_(_cluster_Yeg_) ADP-ribosylglycohydrolase YegU (EC 3.2.-.-) Fimbriae usher protein StcC Fructose-bisphosphate aldolase class I (EC 4.1.2.13) Glycosyl hydrolase YegX, family 25 Putative nucleoside transporter YegT Uncharacterized HTH-type transcriptional regulator YegW Uncharacterized fimbrial chaperone YehC precursor Uncharacterized protein YehA precursor Uncharacterized protein YohN precursor Uncharacterized sugar kinase YegV, PfkB family Unknown_sugar_utilization_(cluster_yphABCDEFG) Aldose 1-epimerase family protein YphB Hypothetical zinc-type alcohol dehydrogenase-like protein YphC Inner membrane protein YphA Predicted sugar ABC transport system, ATP-binding protein YphE Predicted sugar ABC transport system, periplasmic binding protein YphF precursor Predicted sugar ABC transport system, permease protein YphD Uncharacterized protein YphG, TPR-domain containing VC0266 Hypothetical protein VC0266 (sugar utilization related?) beta-glucuronide_utilization Beta-glucuronidase (EC 3.2.1.31) Glucuronide transport facilitator UidC Glucuronide transporter UidB Transcriptional repressor UidR 01 Cell Division and Cell Cycle Bacterial_Cytoskeleton Cell division initiation protein DivIVA Cell division protein FtsA Cell division protein FtsB Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) Cell division protein FtsK Cell division protein FtsL Cell division protein FtsN Cell division protein FtsQ Cell division protein FtsQ homolog Cell division protein FtsW Cell division protein FtsZ (EC 3.4.24.-) Cell division protein MraZ Cell division protein ZipA Cell division topological specificity factor MinE Cell-shape determining protein MreBH Chromosome (plasmid) partitioning protein ParA Chromosome (plasmid) partitioning protein ParB MreB-like protein (Mbl protein) Penicillin-binding protein PBP2 Rod shape-determining protein MreB Rod shape-determining protein MreC Rod shape-determining protein MreD Rod shape-determining protein RodA Septum formation protein Maf Septum site-determining protein MinC Septum site-determining protein MinD Sporulation initiation inhibitor protein Soj Stage 0 sporulation protein J Z-ring-associated protein ZapA Control_of_cell_elongation_-_division_cycle_in_Bacilli Cell division protein GpsB, coordinates the switch between cylindrical and septal cell wall synthesis by re-localization of PBP1 Chromosome replication initiation protein dnaD Endonuclease III (EC 4.2.99.18) FIG001721: Predicted N6-adenine-specific DNA methylase FIG005686: hypothetical protein Hypothetical protein in cluster with penicillin-binding protein PBP1, Bacillus type Hypothetical protein in cluster with penicillin-binding protein PBP1, Listerial type Hypothetical protein in cluster with penicillin-binding protein PBP1, Staphylococcal type Penicillin-binding protein 1A/1B (PBP1) Recombination protein RecU Septation ring formation regulator EzrA Uncharacterized protein YppC Cyanobacterial_Circadian_Clock Circadian clock protein KaiA Circadian clock protein KaiC Circadian input kinase A Circadian oscillation regulator KaiB Circadian period extender Pex Circadian phase modifier Clock-associated two-component sensor histidine kinase SasA Group 2 RNA polymerase sigma factor Light dependent period modulator LdpA Heterocyst_formation_in_cyanobacteria Global nitrogen regulatory protein, CRP family of transcriptional regulators Heterocyst differentiation protein HetC Heterocyst differentiation protein HetP Heterocyst formation inhibiting signaling peptide PatS Main regulator of heterocyst differentiation HetR Nitrogen-responsive response regulator NrrA Protein FraG required for filament integrity and heterocyst maturation Intracellular_septation_in_Enterobacteria Acyl-CoA thioesterase YciA, involved in membrane biogenesis Intracellular septation protein IspA Membrane protein YciC, linked to IspA Macromolecular_synthesis_operon Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) DNA primase (EC 2.7.7.-) RNA polymerase sigma factor RpoD SSU ribosomal protein S21p Transamidase GatB domain protein YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA MukBEF_Chromosome_Condensation Chromosome partition protein MukB Chromosome partition protein MukE Chromosome partition protein MukF Membrane Protein Functionally coupled to the MukBEF Chromosome Partitioning Mechanism S-adenosylmethionine-dependent methyltransferase Functionally Coupled to the MukBEF Chromosome Partitioning Mechanism Two_cell_division_clusters_relating_to_chromosome_partitioning Chromosome (plasmid) partitioning protein ParA Chromosome (plasmid) partitioning protein ParB Chromosome (plasmid) partitioning protein ParB-2 Chromosome partition protein smc Pseudouridine synthase family protein Ribonuclease III (EC 3.1.26.3) Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) Segregation and condensation protein A Segregation and condensation protein B Signal recognition particle associated protein Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1) Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1) YgjD_and_YeaZ Inactive homolog of metal-dependent proteases, putative molecular chaperone YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA p53-regulating protein kinase (human PRPK/yeast YGR262c) 01 Cell Wall and Capsule 02 Capsular and extracellular polysacchrides Alginate_metabolism Alginate biosynthesis protein Alg8 Alginate biosynthesis protein AlgX Alginate biosynthesis transcriptional activator Alginate lyase (EC 4.2.2.3) Alginate lyase precursor (EC 4.2.2.3) GDP-mannose 6-dehydrogenase (EC 1.1.1.132) Hexuronate transporter Mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) Mannose-6-phosphate isomerase (EC 5.3.1.8) Pectin degradation protein KdgF Phosphomannomutase (EC 5.4.2.8) Poly(beta-D-mannuronate) C5 epimerase precursor (EC 5.1.3.-) Probable poly(beta-D-mannuronate) O-acetylase (EC 2.3.1.-) RNA polymerase sigma-H factor AlgT alginate biosynthesis protein AlgJ alginate o-acetyltransferase AlgF outer membrane protein AlgE poly(beta-D-mannuronate) lyase (EC 4.2.2.3) CMP-N-acetylneuraminate_Biosynthesis N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) N-acetylneuraminate synthase (EC 2.5.1.56) Sialic acid biosynthesis protein NeuD, O-acetyltransferase UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) Capsular_Polysaccharide_(CPS)_of_Campylobacter Capsular polysaccharide ABC transporter, ATP-binding protein KpsT Capsular polysaccharide ABC transporter, permease protein KpsM Capsular polysaccharide export system inner membrane protein KpsE Capsular polysaccharide export system periplasmic protein KpsD Capsular polysaccharide export system protein KpsF Capsular_Polysaccharides_Biosynthesis_and_Assembly CMP-Kdo synthetase, KpsU Capsular polysaccharide ABC transporter, ATP-binding protein KpsT Capsular polysaccharide ABC transporter, permease protein KpsM Capsular polysaccharide biosynthesis protein CapD Capsular polysaccharide biosynthesis protein WcbF Capsular polysaccharide biosynthesis protein WcbJ, NAD-dependent epimerase/dehydratase family Capsular polysaccharide biosynthesis protein WcbQ Capsular polysaccharide biosynthesis/export periplasmic protein WcbA Capsular polysaccharide biosynthesis/export periplasmic protein WcbC Capsular polysaccharide export system inner membrane protein KpsE Capsular polysaccharide export system periplasmic protein KpsD Capsular polysaccharide export system protein KpsC Capsular polysaccharide export system protein KpsS Capsular polysaccharide glycosyltransferase biosynthesis protein WcbB D-glycero-D-manno-heptose 1-phosphate guanosyltransferase Glycosyl transferase, group 1 family protein (EC 2.4.1.-) Low molecular weight protein-tyrosine-phosphatase Wzb (EC 3.1.3.48) O-antigen flippase Wzx Oligosaccharide repeat unit polymerase Wzy Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) Phosphoanhydride phosphohydrolase (EC 3.1.3.2) (pH 2.5 acid phosphatase) (AP) Polysaccharide export lipoprotein Wza Putative capsular polysaccharide transport protein YegH Putative outer membrane lipoprotein YmcA Putative polysaccharide export protein YccZ precursor Putative uncharacterized protein YmcB Tyrosine-protein kinase Wzc (EC 2.7.10.2) UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) Uncharacterized lipoprotein YmcC precursor Capsular_heptose_biosynthesis Capsular polysaccharide biosynthesis fatty acid synthase WcbR Capsular polysaccharide biosynthesis heptosyltransferase HddD Capsular polysaccharide biosynthesis protein WcbJ, NAD-dependent epimerase/dehydratase family D,D-heptose 7-phosphate kinase D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) D-glycero-D-manno-heptose 1-phosphate guanosyltransferase GDP-L-fucose synthetase (EC 1.1.1.271) GDP-mannose 4,6-dehydratase (EC 4.2.1.47) Methyltransferase, FkbM family protein Phosphoheptose isomerase (EC 5.3.1.-) Phosphoheptose isomerase 1 (EC 5.3.1.-) Phosphoheptose isomerase 2 (EC 5.3.1.-) dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) Capsular_surface_virulence_antigen_loci Insertion element IS1 protein insA Insertion element IS1 protein insB Vi polysaccharide biosynthesis protein tviA Vi polysaccharide biosynthesis protein tviC Vi polysaccharide biosynthesis protein tviD Vi polysaccharide biosynthesis protein tviE Vi polysaccharide export ATP-binding protein vexC Vi polysaccharide export inner-membrane protein vexB Vi polysaccharide export inner-membrane protein vexD Vi polysaccharide export protein vexE Colanic_acid_biosynthesis Colanic acid biosynthesis acetyltransferase WcaB (EC 2.3.1.-) Colanic acid biosynthesis acetyltransferase WcaF (EC 2.3.1.-) Colanic acid biosynthesis glycosyl transferase WcaA Colanic acid biosynthesis glycosyl transferase WcaC Colanic acid biosynthesis glycosyl transferase WcaE Colanic acid biosynthesis glycosyl transferase WcaL Colanic acid biosynthsis UDP-glucose lipid carrier transferase WcaJ Colanic acid biosysnthesis glycosyl transferase WcaI Colanic acid biosysnthesis protein WcaK Colanic acid polymerase WcaD GDP-L-fucose synthetase (EC 1.1.1.271) GDP-mannose 4,6-dehydratase (EC 4.2.1.47) GDP-mannose mannosyl hydrolase (EC 3.6.1.-) Lipopolysaccharide biosynthesis protein WzxC Low molecular weight protein-tyrosine-phosphatase Wzb (EC 3.1.3.48) Polysaccharide export lipoprotein Wza Tyrosine-protein kinase Wzc (EC 2.7.10.2) Exopolysaccharide_Biosynthesis Capsular polysaccharide synthesis enzyme CpsA, sugar transferase Capsular polysaccharide synthesis enzyme CpsB Capsular polysaccharide synthesis enzyme CpsC, polysaccharide export Capsular polysaccharide synthesis enzyme CpsD, exopolysaccharide synthesis Capsular polysaccharide synthesis enzyme CpsE Capsular polysaccharide synthesis enzyme CpsH Conserved domain protein in cluster with two glycosyl transferases Exopolysaccharide biosynthesis glycosyltransferase EpsF (EC 2.4.1.-) Exopolysaccharide biosynthesis transcription antiterminator, LytR family Exopolysaccharide biosynthesis transcriptional activator EpsA Glycosyl transferase, group 1 family protein Glycosyl transferase, group 2 family protein Lipopolysaccharide cholinephosphotransferase LicD3 (EC 2.7.8.-) Manganese-dependent protein-tyrosine phosphatase (EC 3.1.3.48) Putative uncharacterized protein in cluster with two glycosyl transferases Tyrosine-protein kinase EpsD (EC 2.7.10.2) Tyrosine-protein kinase transmembrane modulator EpsC Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) Extracellular_Polysaccharide_Biosynthesis_of_Streptococci Capsular polysaccharide biosynthesis protein Cps4E Capsular polysaccharide biosynthesis protein CpsK(V) Capsular polysaccharide biosythesis protein CpsI Capsular polysaccharide repeat unit transporter CpsL Capsular polysaccharide repeating-unit polymerase CpsH Exopolysaccharide biosynthesis transcriptional activator EpsA Galactosyl transferase CpsE (EC 2.7.8.-) Glycosyl transferase CpsG Membrane protein CarB involved in the export of O-antigen and teichoic acid, Streptococci specific Polysaccharide biosynthesis glycosyl transferase CpsJ Polysaccharide biosynthesis glycosyl transferase CpsN Polysaccharide biosynthesis glycosyl transferase CpsO Polysaccharide biosynthesis protein CpsF Polysaccharide biosynthesis protein CpsH(V) Polysaccharide biosynthesis protein CpsM(V) Tyrosine-protein kinase EpsD (EC 2.7.10.2) Tyrosine-protein kinase transmembrane modulator EpsC Tyrosine-protein phosphatase CpsB (EC 3.1.3.48) Legionaminic_Acid_Biosynthesis Bacillosamine/Legionaminic acid biosynthesis N-acetyltrasferase PglD (PseH and NeuD homolog) Bacillosamine/Legionaminic acid biosynthesis aminotransferase PglE Legionaminic acid biosynthesis protein PtmA Legionaminic acid biosynthesis protein PtmF Legionaminic acid biosynthesis protein PtmG Legionaminic acid cytidylyltransferase (EC 2.7.7.43) Legionaminic acid synthase (EC 2.5.1.56) UDP-Bac2Ac4Ac hydrolyzing 2-epimerase NeuC homolog UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) O-Methyl_Phosphoramidate_Capsule_Modification_in_Campylobacter Adenylylsulfate kinase (EC 2.7.1.25) Putative amidotransferase (Type 1 glutamine amidotransferase - GATase1) Putative glycosyltransferase involved in O-methyl phosphoramidate capsule modification Putative sugar nucleotidyltransferase Pyruvate phosphate dikinase Phosphorylcholine_incorporation_in_LPS Choline kinase (EC 2.7.1.32) Choline permease LicB Cholinephosphate cytidylyltransferase (EC 2.7.7.15) Lipopolysaccharide cholinephosphotransferase LicD1 (EC 2.7.8.-) Lipopolysaccharide cholinephosphotransferase LicD2 (EC 2.7.8.-) Polysaccharide_deacetylases Peptidoglycan N-acetylglucosamine deacetylase (EC 3.5.1.-) Polysaccharide deacetylase Polysaccharide intercellular adhesin (PIA) biosynthesis deacetylase IcaB (EC 3.-.-.-) Pseudaminic_Acid_Biosynthesis C4 aminotransferase specific for PseB product (PseC, second step of pseudaminic acid biosynthesis) N-Acetyltransferase PseH involved in the biosynthesis of pseudaminic acid Pseudaminic acid biosynthesis protein PseA, possible Pse5Ac7Ac acetamidino synthase Pseudaminic acid cytidylyltransferase (EC 2.7.7.43) Pseudaminic acid synthase (EC 4.1.3.-) UDP-6-deoxy-AltdiNAc hydrolase (PseG, third step of pseudaminic acid biosynthesis) UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase (PseB, first step of pseudaminic acid biosynthesis) Rhamnose_containing_glycans Alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase (EC 2.4.1.-) Alpha-L-Rha alpha-1,2-L-rhamnosyltransferase/alpha-L-Rha alpha-1,3-L- rhamnosyltransferase (EC 2.4.1.-) Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) Capsular polysaccharide ABC transporter, permease protein KpsM Capsular polysaccharide biosynthesis/export periplasmic protein WcbA Capsular polysaccharide export system protein KpsC DNA for glycosyltransferase, lytic transglycosylase, dTDP-4-rhamnose reductase Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) Glycerol-3-phosphate cytidylyltransferase (EC 2.7.7.39) Heteropolysaccharide repeat unit export protein Polysialic acid transport protein KpsM Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) UDP-glucose 4-epimerase (EC 5.1.3.2) capsular polysaccharide biosynthesis protein dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) putative glycosyltransferase - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide putative polysialic acid transport protein Serotype_determining_Capsular_polysaccharide_biosynthesis_in_Staphylococcus Capsular polysaccharide synthesis enzyme Cap5A Capsular polysaccharide synthesis enzyme Cap5B Capsular polysaccharide synthesis enzyme Cap5C Capsular polysaccharide synthesis enzyme Cap5D Capsular polysaccharide synthesis enzyme Cap5E Capsular polysaccharide synthesis enzyme Cap5F Capsular polysaccharide synthesis enzyme Cap5G Capsular polysaccharide synthesis enzyme Cap5H Capsular polysaccharide synthesis enzyme Cap5I Capsular polysaccharide synthesis enzyme Cap5J Capsular polysaccharide synthesis enzyme Cap5K Capsular polysaccharide synthesis enzyme Cap5L Capsular polysaccharide synthesis enzyme Cap5M Capsular polysaccharide synthesis enzyme Cap5O Capsular polysaccharide synthesis enzyme Cap8A Capsular polysaccharide synthesis enzyme Cap8B Capsular polysaccharide synthesis enzyme Cap8C Capsular polysaccharide synthesis enzyme Cap8D Capsular polysaccharide synthesis enzyme Cap8E Capsular polysaccharide synthesis enzyme Cap8F Capsular polysaccharide synthesis enzyme Cap8G Capsular polysaccharide synthesis enzyme Cap8H Capsular polysaccharide synthesis enzyme Cap8I Capsular polysaccharide synthesis enzyme Cap8J Capsular polysaccharide synthesis enzyme Cap8L Capsular polysaccharide synthesis enzyme Cap8M Capsular polysaccharide synthesis enzyme Cap8N Capsular polysaccharide synthesis enzyme Cap8O Capsular polysaccharide synthesis enzyme Cap8P Sialic_Acid_Metabolism ABC transporter, predicted N-acetylneuraminate transport system permease protein 1 ABC transporter, predicted N-acetylneuraminate transport system permease protein 2 ABC transporter, predicted N-acetylneuraminate-binding protein Beta-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-) CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Glucosamine-6-phosphate deaminase (EC 3.5.99.6) N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) N-acetylmannosamine kinase (EC 2.7.1.60) N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) N-acetylneuraminate lyase (EC 4.1.3.3) N-acetylneuraminate mutarotase N-acetylneuraminate synthase (EC 2.5.1.56) N-acetylneuraminic acid outer membrane channel protein NanC N-acylglucosamine 2-epimerase (EC 5.1.3.8) PTS system, N-acetylglucosamine-specific IIA component (EC 2.7.1.69) PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) PTS system, N-acetylmuramic acid-specific IIB component (EC 2.7.1.69) PTS system, N-acetylmuramic acid-specific IIC component (EC 2.7.1.69) PTS system, mannose-specific IIA component (EC 2.7.1.69) PTS system, mannose-specific IIB component (EC 2.7.1.69) PTS system, mannose-specific IIC component (EC 2.7.1.69) PTS system, mannose-specific IID component (EC 2.7.1.69) Phosphoglucosamine mutase (EC 5.4.2.10) Predicted sialic acid transporter Putative sugar isomerase involved in processing of exogenous sialic acid Sialic acid biosynthesis protein NeuD, O-acetyltransferase Sialic acid transporter (permease) NanT Sialic acid utilization regulator, RpiR family Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase Sialidase (EC 3.2.1.18) TRAP-type transport system, large permease component, predicted N-acetylneuraminate transporter TRAP-type transport system, periplasmic component, predicted N-acetylneuraminate-binding protein TRAP-type transport system, small permease component, predicted N-acetylneuraminate transporter Transcriptional regulator NanR UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) Streptococcal_Hyaluronic_Acid_Capsule Hyaluronan synthase (EC 2.4.1.212) UDP-glucose dehydrogenase (EC 1.1.1.22) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) Vibrio_Polysaccharide_(VPS)_Biosynthesis CapK protein, putative Capsular polysaccharide synthesis enzyme CpsA, sugar transferase Capsular polysaccharide synthesis enzyme CpsB Capsular polysaccharide synthesis enzyme CpsC, polysaccharide export Capsular polysaccharide synthesis enzyme CpsD, exopolysaccharide synthesis Hemolysin-related protein RbmC Hemolysin-related protein Vcp Hypothetical protein RbmB Hypothetical protein RbmE Hypothetical protein RbmF Hypothetical protein VpsF Hypothetical protein VpsJ Hypothetical protein VpsP Hypothetical protein VpsQ Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) N-acetylmannosaminyltransferase (EC 2.4.1.187) Quorum-sensing regulator of virulence HapR RbmA protein RbmD, similar to Lipid A core - O-antigen ligase and related enzymes Serine acetyltransferase (EC 2.3.1.30) Transcriptional regulator CdgA Transcriptional regulator VpsR Transcriptional regulator VpsT UDP-N-acetyl-D-mannosaminuronate dehydrogenase UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) exopolysaccharide biosynthesis protein EpsF, putative polysaccharide biosynthesis protein, putative polysaccharide export protein, putative Xanthan_Exopolysaccharide_Biosynthesis_and_Export Outer membrane protein GumB, involved in the export of xanthan Xanthan biosynthesis acetyltransferase GumF Xanthan biosynthesis acetyltransferase GumG Xanthan biosynthesis chain length determinant protein GumC Xanthan biosynthesis exopolysaccharide polymerase GumE Xanthan biosynthesis glucuronosyltransferase GumK Xanthan biosynthesis glycosyltransferase GumD Xanthan biosynthesis glycosyltransferase GumH Xanthan biosynthesis glycosyltransferase GumI Xanthan biosynthesis glycosyltransferase GumM Xanthan biosynthesis oligosaccharidyl-lipid flippase GumJ Xanthan biosynthesis pyruvyltransferase GumL YjbEFGH_Locus_Involved_in_Exopolysaccharide_Production YjbE secreted protein YjbF outer membrane lipoprotein YjbG polysaccharide synthesis-related protein YjbH outer membrane lipoprotein dTDP-rhamnose_synthesis Glucose-1-phosphate cytidylyltransferase (EC 2.7.7.33) Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) dTDP-rhamnosyl transferase RfbF (EC 2.-.-.-) 02 Cell wall of Mycobacteria mycolic_acid_synthesis 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III FABH (BETA-KETOACYL-ACP SYNTHASE III) (KAS III) 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 Acyl carrier protein CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7 CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 1 CMAA1 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 1) CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 2) (MYCOLIC ACID TRANS-CYCLOPROPANE SYNTHETASE) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE) METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2 (METHYL MYCOLIC ACID SYNTHASE 2) (MMA2) (HYDROXY MYCOLIC ACID SYNTHASE) METHOXY MYCOLIC ACID SYNTHASE 3 MMAA3 (METHYL MYCOLIC ACID SYNTHASE 3) (MMA3) (HYDROXY MYCOLIC ACID SYNTHASE) METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) MYCOLIC ACID SYNTHASE (PcaA/UmaA2) (CYCLOPROPANE SYNTHASE) Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA5 POSSIBLE LINOLEOYL-CoA DESATURASE (DELTA(6)-DESATURASE) POSSIBLE MYCOLIC ACID SYNTHASE UMAA1 PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DRRA PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRB PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRC PROBABLE MULTIFUNCTIONAL MYCOCEROSIC ACID SYNTHASE MEMBRANE-ASSOCIATED MAS Phenolpthiocerol synthesis polyketide synthase ppsA Phenolpthiocerol synthesis polyketide synthase ppsB Probable acyl-[acyl-carrier protein] desaturase DESA1 (Acyl-[ACP] desaturase) (Stearoyl-ACP desaturase) (Protein DES) (EC 1.14.19.2) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) (FIBRONECTIN-BINDING PROTEIN A) (ANTIGEN 85 COMPLEX A) SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR ALPHA-ANTIGEN) SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) acyl-CoA synthetase 02 Gram-Negative cell wall components Core_Oligosaccharide_Glycosylation_in_Pseudomonas Carbamoyltransferase in large core OS assembly cluster Glycosyl transferase in large core OS assembly cluster Glycosyltransferase (EC 2.4.1.-) in large core OS assembly cluster Hypothetical protein FIG015671 in large core OS assembly cluster Probable transcription regulator Mig-14 alpha-1,3-rhamnosyltransferase alpha-1,6-rhamnosyltransferase alpha-1,6-rhamnosyltransferase paralog Inner_membrane_protein_YhjD_and_conserved_cluster_involved_in_LPS_biosynthesis GGDEF/EAL domain protein YhjH Inner membrane metabolite transport protein YhjE Inner membrane protein YhjD LysR family transcriptional regulator YhjC Protein YhjJ, putative peptidase Uncharacterized protein YhjG KDO2-Lipid_A_biosynthesis 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase (EC 2.5.1.55) 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) 3-deoxy-D-manno-octulosonic-acid transferase (EC 2.-.-.-) 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (EC 2.3.1.129) Arabinose 5-phosphate isomerase (EC 5.3.1.13) LPS-assembly lipoprotein RlpB precursor (Rare lipoprotein B) Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.25) Lipid-A-disaccharide synthase (EC 2.4.1.182) Lipopolysaccharide ABC transporter, ATP-binding protein LptB LptA, protein essential for LPS transport across the periplasm O-antigen flippase Wzx Oligosaccharide repeat unit polymerase Wzy Predicted hydrolase of the metallo-beta-lactamase superfamily, clustered with KDO2-Lipid A biosynthesis genes Protein of unknown function DUF1009 clustered with KDO2-Lipid A biosynthesis genes Tetraacyldisaccharide 4'-kinase (EC 2.7.1.130) UDP-2,3-diacylglucosamine hydrolase (EC 3.6.1.-) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (EC 3.5.1.-) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) regulator of length of O-antigen component of lipopolysaccharide chains LOS_core_oligosaccharide_biosynthesis 3-deoxy-D-manno-octulosonic-acid transferase (EC 2.-.-.-) ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) ADP-heptose synthase (EC 2.7.-.-) ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) Beta-1,3-glucosyltransferase Beta-1,4-galactosyltransferase D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) D-glycero-beta-D-manno-heptose 7-phosphate kinase Heptosyltransferase family protein, lipopolysaccharide core biosynthesis Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC 2.4.1.56) Lipopolysaccharide 1,6-galactosyltransferase (EC 2.4.1.-) Lipopolysaccharide core biosynthesis glycosyltransferase, group 2 family protein (EC 2.4.1.-) Lipopolysaccharide core biosynthesis protein RfaS Lipopolysaccharide core biosynthesis protein RfaY Lipopolysaccharide core biosynthesis protein RfaZ Lipopolysaccharide core biosynthesis protein WaaP (EC 2.7.-.-), heptosyl-I-kinase Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) Lipopolysaccharide heptosyltransferase III (EC 2.4.1.-) O-antigen ligase Phosphoheptose isomerase (EC 5.3.1.-) Phosphoheptose isomerase 1 (EC 5.3.1.-) Phosphoheptose isomerase 2 (EC 5.3.1.-) Putative two-domain glycosyltransferase UDP-galactopyranose mutase (EC 5.4.99.9) UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW (EC 2.4.1.-) UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,2-glucosyltransferase (EC 2.4.1.58) UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,3-glucosyltransferase WaaO (EC 2.4.1.-) UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG (EC 2.4.1.-) Lipid_A-Ara4N_pathway_(_Polymyxin_resistance_) Polymyxin resistance protein ArnA_DH, UDP-glucuronic acid decarboxylase (EC 4.1.1.-) Polymyxin resistance protein ArnA_FT, UDP-4-amino-4-deoxy-L-arabinose formylase (EC 2.1.2.-) Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) Polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase Polymyxin resistance protein PmrD Polymyxin resistance protein PmrG Polymyxin resistance protein PmrJ, predicted deacetylase Polymyxin resistance protein PmrL, sucrose-6 phosphate hydrolase Polymyxin resistance protein PmrM UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.-) UDP-glucose dehydrogenase (EC 1.1.1.22) Lipid_A_modifications Fe(2+)/alpha-ketoglutarate-dependent dioxygenase LpxO Lipid A 3-O-deacylase Lipid A acylation protein PagP, palmitoyltransferase Phosphoethanolamine transferase EptA specific for the 1 phosphate group of core-lipid A Phosphoethanolamine transferase specific for the outer Kdo residue of lipopolysaccharide Sensor protein PhoQ (EC 2.7.13.3) Sensor protein basS/pmrB (EC 2.7.3.-) Transcriptional regulatory protein PhoP Transcriptional regulatory protein basR/pmrA UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide Lipopolysaccharide-related_cluster_in_Alphaproteobacteria 3-deoxy-D-manno-octulosonic-acid transferase (EC 2.-.-.-) FIG043197: Inositol monophosphatase family protein FIG062860: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) FIG081201: hypothetical protein FIG146212: Enoyl-CoA hydratase (EC 4.2.1.17) Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.25) Protein of unknown function DUF374 Tetraacyldisaccharide 4'-kinase (EC 2.7.1.130) TldE/PmbA protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038) Uncharacterized protein, Bsl7517 homolog Lipopolysaccharide_assembly HtrA protease/chaperone protein Inner membrane protein YrbG, predicted calcium/sodium:proton antiporter LPS-assembly lipoprotein RlpB precursor (Rare lipoprotein B) Lipopolysaccharide ABC transporter, ATP-binding protein LptB Lipoprotein releasing system ATP-binding protein LolD Lipoprotein releasing system transmembrane protein LolC Lipoprotein releasing system transmembrane protein LolE LptA, protein essential for LPS transport across the periplasm Outer membrane chaperone Skp (OmpH) precursor Outer membrane lipoprotein LolB precursor Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex Outer membrane lipoprotein carrier protein LolA Outer membrane protein Imp, required for envelope biogenesis Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL) Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) Outer membrane protein assembly factor YaeT precursor Probable component of the lipoprotein assembly complex (forms a complex with YaeT, YfgL, and NlpB) Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) Uncharacterized ABC transporter, ATP-binding protein YrbF Uncharacterized ABC transporter, auxiliary component YrbC Uncharacterized ABC transporter, periplasmic component YrbD Uncharacterized ABC transporter, permease component YrbE Uncharacterized protein YrbK clustered with lipopolysaccharide transporters Lipoprotein_sorting_system Lipoprotein releasing system ATP-binding protein LolD Lipoprotein releasing system transmembrane protein LolC Lipoprotein releasing system transmembrane protein LolE Outer membrane lipoprotein LolB precursor Outer membrane lipoprotein carrier protein LolA Major_Outer_Membrane_Proteins Attachment invasion locus protein precursor Integral membrane protein YfiB Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein) Nucleoside-specific channel-forming protein Tsx precursor Osmolarity sensory histidine kinase EnvZ Outer membrane protein A precursor Outer membrane protein C precursor Outer membrane protein H precursor Outer membrane protein Lom Outer membrane protein N precursor Outer membrane protein OmpK Outer membrane protein OmpT Outer membrane protein OmpU Outer membrane protein OmpV Outer membrane protein W precursor Outer membrane protein X precursor Protease VII (Omptin) precursor (EC 3.4.23.49) Two-component system response regulator OmpR Outer_membrane Outer membrane protein A precursor Outer membrane protein C precursor Outer membrane protein F precursor Outer membrane protein G precursor Outer membrane protein H precursor Outer membrane protein assembly factor YaeT precursor Perosamine_Synthesis_Vibrio GDP-mannose 4,6-dehydratase (EC 4.2.1.47) Mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) O-antigen export system, ATP-binding protein O-antigen export system, permease protein O-antigen export system, polymerase or transferase Phosphomannomutase (EC 5.4.2.8) Vibrio_Core_Oligosaccharide_Biosynthesis 3-deoxy-D-manno-octulosonic acid kinase (EC 2.7.1.-) 3-deoxy-D-manno-octulosonic-acid transferase (EC 2.-.-.-) ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) ADP-heptose--lipooligosaccharide heptosyltransferase, putative Lipopolysaccharide biosynthesis glycosyltransferase Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) Lipopolysaccharide synthesis protein WavD Lipopolysaccharide synthesis protein WavE Mannosyltransferase OCH1 and related enzymes Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) O-antigen ligase Polysaccharide deacetylase capsular polysaccharide biosynthesis protein capsular polysaccharide biosynthesis protein, putative lipopolysaccharide biosynthesis protein, putative transferase, hexapeptide repeat family 02 Gram-Positive cell wall components Anthrose_Biosynthesis Aminotransferase, anthrose biosynthesis Enoyl-CoA hydratase (EC 4.2.1.17), anthrose biosynthesis Glycosyl transferase ,group 2 family, anthrose biosynthesis Glycosyl transferase, group 1 family, anthrose biosynthesis Methyltransferase, anthrose biosynthesis O-acetyltransferase, anthrose biosynthesis D-Alanyl_Lipoteichoic_Acid_Biosynthesis D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13) D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13) D-alanyl transfer protein DltB Poly(glycerophosphate chain) D-alanine transfer protein DltD Polyglycerolphosphate_lipoteichoic_acid_biosynthesis Glycosyltransferase LafA, responsible for the formation of Glc-DAG Glycosyltransferase LafB, responsible for the formation of Gal-Glc-DAG Integral membrane protein LafC, accessory function in glycolipid and LTA synthesis Lipoteichoic acid primase LtaP Lipoteichoic acid synthase LtaS Type IIIa Lipoteichoic acid synthase LtaS Type IIIb1 Lipoteichoic acid synthase LtaS Type IIIb2 Lipoteichoic acid synthase LtaS Type IIa Lipoteichoic acid synthase LtaS Type IIb Lipoteichoic acid synthase LtaS Type IIc Lipoteichoic acid synthase LtaS Type IVa Lipoteichoic acid synthase LtaS Type IVb Lipoteichoic acid synthase LtaS Type Ia Lipoteichoic acid synthase LtaS Type Ib Sortase Cell surface protein IsdA, transfers heme from hemoglobin to apo-IsdC Cell wall surface anchor family protein Cell wall surface anchor family protein, FPXTG motif Cell wall surface anchor family protein, LPXTG motif LPXTG specific sortase A NPQTN specific sortase B Sortase A, LPXTG specific Sortase C, subfamily 3, QVPTGV specific Teichoic_and_lipoteichoic_acids_biosynthesis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) CDP-glycerol: N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenyl glycerophosphotransferase CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (EC 2.7.8.12) CDP-ribitol:poly(ribitol phosphate) ribitol phosphotransferase COG1887: Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13) D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13) D-alanyl transfer protein DltB DltD protein Glycosyl transferase involved in teichoic acid biosynthesis Hypohetical Teichoic Acid Biosynthesis Protein Lipopolysaccharide cholinephosphotransferase LicD3 (EC 2.7.8.-) Membrane protein CarB involved in the export of O-antigen and teichoic acid, Streptococci specific Minor teichoic acid biosynthesis protein GgaA Minor teichoic acid biosynthesis protein GgaB Monogalactosyldiacylglycerol synthase (EC 2.4.1.46) Monogalactosyldiacylglycerol synthase precursor N-acetylmannosaminyltransferase (EC 2.4.1.187) Poly(glycerol-phosphate) alpha-glucosyltransferase (EC 2.4.1.52) Poly(glycerophosphate chain) D-alanine transfer protein DltD Putative CDP-glycerol:glycerophosphate glycerophosphotransferase (EC 2.7.8.-) Putative CDP-glycosylpolyol phosphate:glycosylpolyol glycosylpolyolphosphotransferase Putative glycosyl/glycerophosphate transferase in teichoic acid biosynthesis Putative major teichoic acid biosynthesis protein C Putative polyribitolphosphotransferase Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltR Regulation of D-alanyl-lipoteichoic acid biosynthesis, sensor histidine kinase Teichoic acid biosynthesis protein Teichoic acid biosynthesis protein X Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) Teichoic acid glycosylation protein Teichoic acid translocation permease protein TagG Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) diglucosyldiacylglycerol synthase (LTA membrane anchor synthesis) galactosamine-containing minor teichoic acid biosynthesis protein ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) Teichuronic_acid_biosynthesis Putative N-acetylgalactosaminyl-diphosphoundecaprenol glucuronosyltransferase Putative teichuronic acid biosynthesis glycosyl transferase TuaC Putative teichuronic acid biosynthesis glycosyl transferase TuaH Teichuronic acid biosynthesis protein TuaB Teichuronic acid biosynthesis protein TuaE, putative secreted polysaccharide polymerase Teichuronic acid biosynthesis protein TuaF UDP-glucose dehydrogenase (EC 1.1.1.22) 02 Murein_Hydrolases Beta N-acetyl-glucosaminidase (EC 3.2.1.52) D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase C precursor (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase E (EC 3.2.1.-) Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) Peptidoglycan_Biosynthesis Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) D-alanine--D-alanine ligase (EC 6.3.2.4) D-alanine--D-alanine ligase A (EC 6.3.2.4) D-alanine--D-alanine ligase B (EC 6.3.2.4) D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Glutamate racemase (EC 5.1.1.3) Glutamine synthetase type I (EC 6.3.1.2) Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) Glutamine synthetase type III, GlnN (EC 6.3.1.2) Glutamine synthetase, clostridia type (EC 6.3.1.2) Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) Murein-DD-endopeptidase (EC 3.4.99.-) N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) N-acetylglucosamine-1-phosphate uridyltransferase eukaryotic (EC 2.7.7.23) Penicillin-binding protein 2 (PBP-2) Penicillin-binding protein 4 precursor Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) Rare lipoprotein A precursor Rod shape-determining protein RodA UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) Peptidoglycan_Crosslinking_of_Peptide_Stems L,D-transpeptidase ErfK L,D-transpeptidase YbiS L,D-transpeptidase YcbB L,D-transpeptidase YcfS L,D-transpeptidase YnhG Penicillin-binding protein AmpH Peptidoglycan_biosynthesis--gjo D-alanine--D-alanine ligase (EC 6.3.2.4) D-alanine--D-alanine ligase A (EC 6.3.2.4) D-alanine--D-alanine ligase B (EC 6.3.2.4) UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (EC 6.3.2.-) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) UDP-N-acetylmuramoylalanyl-D-glutamate--L,L-2,6-diaminopimelate ligase UDP-N-acetylmuramoylalanyl-D-glutamate--L-diaminobutyrate ligase UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase (EC 6.3.2.7) UDP-N-acetylmuramoylalanyl-D-glutamate--L-ornithine ligase UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) Recycling_of_Peptidoglycan_Amino_Acids Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3) AmpG permease Gamma-D-Glutamyl-meso-Diaminopimelate Amidase L-alanine-DL-glutamate epimerase Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD Periplasmic Murein Peptide-Binding Protein MppA UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (EC 6.3.2.-) Recycling_of_Peptidoglycan_Amino_Sugars Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) Beta N-acetyl-glucosaminidase (EC 3.2.1.52) N-acetylmuramic acid 6-phosphate etherase (EC 4.2.-.-) UDP-N-acetylmuramate_from_Fructose-6-phosphate_Biosynthesis Glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Glucosamine-6-phosphate deaminase (EC 3.5.99.6) Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) N-acetylglucosamine-1-phosphate uridyltransferase eukaryotic (EC 2.7.7.23) N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) N-acetylmuramic acid 6-phosphate etherase (EC 4.2.-.-) Phosphoglucosamine mutase (EC 5.4.2.10) UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) YjeE ATPase YjeE, predicted to have essential role in cell wall biosynthesis CBS domain protein sometimes clustered with YjeE COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases Inactive homolog of metal-dependent proteases, putative molecular chaperone YjeF protein, C-terminal domain YjeF protein, function unknown tRNA-dependent_amino_acid_transfers tRNA-dependent lipid II--L-alanine ligase tRNA-dependent lipid II--L-serine ligase tRNA-dependent lipid II--amino acid ligase tRNA-dependent lipid II--glycine ligase tRNA-dependent lipid II--glycine ligase (FmhB) tRNA-dependent lipid II-Ala--L-alanine ligase tRNA-dependent lipid II-Ala--L-serine ligase tRNA-dependent lipid II-AlaAla--L-alanine ligase tRNA-dependent lipid II-AlaAla--L-serine ligase tRNA-dependent lipid II-Gly--glycine ligase tRNA-dependent lipid II-GlyGly--glycine ligase tRNA-dependent lipid II-GlyGlyGly--glycine ligase tRNA-dependent lipid II-GlyGlyGlyGly--glycine ligase tRNA-dependent lipid II-Ser--L-alanine ligase 01 Clustering-based subsystems 02 Biosynthesis of galactoglycans and related lipopolysacharides CBSS-258594.1.peg.3339 Exopolysaccharide production protein ExoF precursor Exopolysaccharide production protein ExoQ Exopolysaccharide production protein ExoZ Glycosyl transferase, group 1 Glycosyltransferase Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) Putative glycosyltransferase protein Secretion protein, HlyD family Tyrosine-protein kinase Wzc (EC 2.7.10.2) Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases putative glycosyltransferase protein CBSS-376686.6.peg.291 Alpha-1,4-N-acetylgalactosamine transferase PglH (EC 2.4.1.-) Apolipoprotein N-acyltransferase (EC 2.3.1.-) Bacterial sugar transferase Glycosyl transferase, family 2 Glycosyl transferase, group 1 Glycosyl transferase, group 1 (EC 2.-.-.-) Glycosyltransferase (EC 2.4.1.-) Hexapeptide transferase family protein Oligosaccharide repeat unit polymerase Wzy glycosyl transferase, family 2 hypothetical protein FP1254 02 CRISPRs and associated hypotheticals CBSS-216592.1.peg.3534 Alkaline phosphatase isozyme conversion protein precursor (EC 3.4.11.-) CRISPR-associated helicase Cas3, protein CRISPR-associated protein Cas1 CRISPR-associated protein, CT1974 CRISPR-associated protein, CT1975 family CRISPR-associated protein, CT1976 CRISPR-associated protein, Cas2 corresponds to STY3070 from Accession AL513382: Salmonella typhi CT18 putative CRISPR associated hypothetical protein 02 Carbohydrates Beta-lactamase_cluster_in_Streptococcus Aquaporin (Major Intrinsic Protein Family) Beta-lactamase, class C C3-degrading proteinase Drug/metabolite transporter (DMT) superfamily protein Hydrolase in cluster with beta-lactamase (HAD superfamily) Putative membrane protein precursor SPs0273 Putative signal peptidase I (EC 3.4.21.89) Pyruvate formate-lyase (EC 2.3.1.54) RecD-like DNA helicase YrrC Transcriptional regulator in cluster with beta-lactamase, GntR family Xaa-Pro dipeptidyl-peptidase (EC 3.4.14.11) Cluster_Ytf_and_putative_sugar_transporter Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) Putative sugar ABC transport system, ATP-binding protein YtfR (EC 3.6.3.17) Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor Putative sugar ABC transport system, permease protein YjfF Putative sugar ABC transport system, permease protein YtfT Putative sugar transporter UPF0131 protein YtfP Uncharacterized protein YtfM precursor Uncharacterized protein YtfN Predicted_mycobacterial_monooxygenase Monooxygenase component A Monooxygenase component C Monooxygenase, FAD- and [2Fe-2S]-containing component B Putative_sugar_ABC_transporter_(ytf_cluster) Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) Putative sugar ABC transport system, ATP-binding protein YtfR (EC 3.6.3.17) Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor Putative sugar ABC transport system, permease protein YjfF Putative sugar ABC transport system, permease protein YtfT UPF0131 protein YtfP Uncharacterized protein YtfM precursor Uncharacterized protein YtfN 02 Carotenoid biosynthesis CBSS-320388.3.peg.3759 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) Phytoene desaturase (EC 1.14.99.-) Phytoene synthase (EC 2.5.1.32) S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) Squalene--hopene cyclase (EC 5.4.99.17) 02 Catabolism of an unknown compound CBSS-262316.1.peg.2929 Aldehyde dehydrogenase in hypothetical Actinobacterial gene cluster Amino acid permease in hypothetical Actinobacterial gene cluster Amino acid/metabolite permease in hypothetical Actinobacterial gene cluster COG2071: predicted glutamine amidotransferases in hypothetical Actinobacterial gene cluster Glutamine synthetase family protein in hypothetical Actinobacterial gene cluster Short-chain dehydrogenase/reductase in hypothetical Actinobacterial gene cluster Transcriptional regulator, GntR family, in hypothetical Actinobacterial gene cluster 02 Cell Division CBSS-393130.3.peg.794 CDS_ID OB2202 Cysteine desulfurase (EC 2.8.1.7) SSU ribosomal protein S4p (S9e) Septation ring formation regulator EzrA Thiamine biosynthesis protein ThiI Cell_Division_Cluster Cell division initiation protein DivIVA Cell division protein FtsA Cell division protein FtsQ Cell division protein FtsZ (EC 3.4.24.-) Cell division protein YlmG/Ycf19 (putative), YggT family FIG001583: hypothetical protein, contains S4-like RNA binding domain FIG001960: FtsZ-interacting protein related to cell division Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC Isoleucyl-tRNA synthetase (EC 6.1.1.5) UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) 02 Chemotaxis, response regulators CBSS-323850.3.peg.3142 Chemotaxis protein CheC -- inhibitor of MCP methylation diguanylate cyclase (GGDEF domain) with PAS/PAC sensor 02 Choline bitartrate degradation, putative CBSS-344610.3.peg.2335 3-isopropylmalate dehydrogenase (EC 1.1.1.85) Choline monooxygenase, alpha subunit (EC 1.14.15.7) Choline monooxygenase, beta subunit (EC 1.14.15.7) Choline-glycine betaine transporter D-malic enzyme (EC 1.1.1.83) Positive regulator of Tartrate dehydrogenase/decarboxylase/D-malic enzyme Putative dioxygenase, alpha subunit (EC 1.-.-.-) Putative dioxygenase, beta subunit (EC 1.-.-.-) Tartrate decarboxylase (EC 4.1.1.73) Tartrate dehydrogenase (EC 1.1.1.93) 02 Chromosome Replication SeqA_and_Co-occurring_Genes Esterase ybfF (EC 3.1.-.-) Phosphoglucomutase (EC 5.4.2.2) SeqA protein, negative modulator of initiation of replication Uncharacterized protein ybfE 02 Clustering-based subsystems CBSS-262719.3.peg.410 Adenylosuccinate synthetase (EC 6.3.4.4) FIG003573: hypothetical protein LSU ribosomal protein L9p Phosphoesterase, DHH family protein Replicative DNA helicase (EC 3.6.1.-) [SA14-24] CBSS-280355.3.peg.2835 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) Biotin operon repressor Biotin-protein ligase (EC 6.3.4.15) Dihydrodipicolinate reductase (EC 1.3.1.26) DinG family ATP-dependent helicase YoaA Lin2022 protein Lmbe-related protein MazG nucleotide pyrophosphohydrolase Methylglyoxal synthase (EC 4.2.3.3) Pantoate--beta-alanine ligase (EC 6.3.2.1) bacteriocin transport accessory protein hypothetical protein BH3604 tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25) CBSS-292415.3.peg.2341 D-serine dehydratase transcriptional activator Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Major facilitator superfamily (MFS) transporter Rhodanese-related sulfurtransferase Putative_diaminopropionate_ammonia-lyase_cluster Aspartate/ornithine carbamoyltransferase family protein protein YgeW CTP:molybdopterin cytidylyltransferase Carbamate kinase-like protein YqeA Hypothetical hydrolase YgeZ (EC 3.-.-.-) Possible hypoxanthine oxidase XdhD (EC 1.-.-.-) Predicted oxidoreductase, Fe-S subunit Putative deacetylase YgeY Putative diaminopropionate ammonia-lyase (EC 4.3.1.15) Putative purine permease YgfO SsnA protein Uncharacterized lipoprotein YgeR precursor Uncharacterized protein YgeP Uncharacterized protein YgfM Uncharacterized protein YgfQ Uncharacterized protein YqeB Uncharacterized protein YqeC Uncharacterized sigma-54-dependent transcriptional regulator YgeV Xanthine dehydrogenase iron-sulfur subunit (EC 1.17.1.4) Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4) Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4) Sporulation-related_Hypotheticals FIG013354: hypothetical protein MreB-like protein (Mbl protein) Stage II sporulation protein D Stage II sporulation protein related to metaloproteases (SpoIIQ) Stage III sporulation protein D UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) 02 Cytochrome biogenesis CBSS-196164.1.peg.1690 ABC-type multidrug transport system, ATPase component ABC-type multidrug transport system, permease component FIG020413: transmembrane protein Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB Iron-sulfur cluster assembly ATPase protein SufC Iron-sulfur cluster assembly protein SufB Iron-sulfur cluster assembly protein SufD Iron-sulfur cluster regulator SufR Probable NADPH:quinone reductase (EC 1.6.5.5) cytochrome oxidase assembly protein CBSS-196164.1.peg.461 Ccs1/ResB-related putative cytochrome C-type biogenesis protein Cytochrome c-type biogenesis protein CcdA (DsbD analog) Cytochrome c-type biogenesis protein CcsA/ResC Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase Hypothetical, related to broad specificity phosphatases COG0406 Hypothetical, similarity to phosphoglycerate mutase Thiol:disulfide oxidoreductase related to ResA 02 D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-) cluster CBSS-342610.3.peg.283 D-tyrosyl-tRNA(Tyr) deacylase Ribonuclease BN (EC 3.1.-.-) 02 DNA metabolism CBSS-269801.1.peg.2186 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) UPF0118 membrane protein YrrI 02 DNA polymerase III epsilon cluster CBSS-342610.3.peg.1536 DNA polymerase III epsilon subunit (EC 2.7.7.7) FIG004599: Hypothetical protein FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) Predicted signal-transduction protein containing cAMP-binding and CBS domains Ribonuclease HI (EC 3.1.26.4) 02 Fatty acid metabolic cluster CBSS-246196.1.peg.364 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) Acyl dehydratase 02 Flagella protein? CBSS-323098.3.peg.2823 Flagellar motor rotation protein MotB MotA/TolQ/ExbB proton channel family protein, probably associated with flagella 02 Hypothetical Related to Dihydroorate Dehydrogenase Hypothetical_Related_to_Dihydroorotate_dehydrogenase Dihydroorotate dehydrogenase (EC 1.3.3.1) FIG005495: hypothetical protein 02 Hypothetical associated with RecF Hypothetical_Coupled_to_RecF DNA recombination and repair protein RecF FIG002958: hypothetical protein 02 Hypothetical in Lysine biosynthetic cluster CBSS-323850.3.peg.3269 2-haloalkanoic acid dehalogenase (EC 3.8.1.2) Diaminopimelate decarboxylase (EC 4.1.1.20) Diaminopimelate epimerase (EC 5.1.1.7) Protein of unknown function DUF484 Tyrosine recombinase XerC 02 Hypothetical lipase related to Phosphatidate metabolism CBSS-316407.3.peg.1371 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) Phosphatidate cytidylyltransferase (EC 2.7.7.41) Putative lipase in cluster with Phosphatidate cytidylyltransferase Ser/Thr and Tyr protein phosphatase (dual specificity) 02 Hypothetical protein possible functionally linked with Alanyl-tRNA synthetase CBSS-257314.1.peg.488 Alanyl-tRNA synthetase (EC 6.1.1.7) Hypothetical protein possible functionally linked with Alanyl-tRNA synthetase Putative Holliday junction resolvase (EC 3.1.-.-) 02 Isoprenoid/cell wall biosynthesis: PREDICTED UNDECAPRENYL DIPHOSPHATE PHOSPHATASE CBSS-83331.1.peg.3039 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1) Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) GCN5-related N-acetyltransferase, FIGfam019367 Membrane-associated zinc metalloprotease Penicillin-binding protein 2 (PBP-2) Penicillin-binding protein 2B Penicillin-binding protein 3 Stage V sporulation protein D (Sporulation-specific penicillin-binding protein) Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31) penicillin-binding protein, putative 02 Lysine Biosynthesis A_Glutathione-dependent_Thiol_Reductase_Associated_with_a_Step_in_Lysine_Biosynthesis FIG138056: a glutathione-dependent thiol reductase N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18) 02 Lysine, threonine, methionine, and cysteine CBSS-84588.1.peg.1247 All3116 protein Aminotransferase ScrA Cysteine desulfurase (EC 2.8.1.7) Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) Diaminopimelate epimerase (EC 5.1.1.7) Tlr0729 protein YeiH DNA binding protein HpkR LysR family transcriptional regulator YeiE Lysine-specific permease Putative membrane protein YeiH 02 Membrane-bound hydrogenase CBSS-69014.3.peg.2094 Energy-conserving [NiFe] hydrogenase (ferredoxin) beta subunit Mbh11 membrane bound hydrogenase beta Membrane bound hydrogenase, 4Fe-4S cluster-binding subunit Membrane bound hydrogenase, MbhA subunit Membrane bound hydrogenase, MbhB subunit Membrane bound hydrogenase, MbhC subunit Membrane bound hydrogenase, MbhE subunit Membrane bound hydrogenase, MbhF subunit Membrane bound hydrogenase, MbhG subunit Membrane bound hydrogenase, MbhH subunit Membrane bound hydrogenase, MbhI subunit Membrane bound hydrogenase, MbhM subunit Membrane bound hydrogenase, NiFe-hydrogenase large subunit 2 Membrane bound hydrogenase, NiFe-hydrogenase small subunit NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) 02 Methylamine utilization CBSS-265072.7.peg.546 Aldehyde dehydrogenase in Methylamine utilization cluster Bacillolysin (EC 3.4.24.28) Cytochrome c in methylamine utilization cluster Methylamine dehydrogenase heavy chain precursor (EC 1.4.99.3) Methylamine dehydrogenase light chain precursor (EC 1.4.99.3) Methylamine operon regulatory protein Methylamine utilization protein MauD Methylamine utilization protein MauE PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain 02 Molybdopterin oxidoreductase CBSS-269799.3.peg.2220 ABC-type Fe3+ transport system protein Molybdenum transport protein, putative Molybdopterin oxidoreductase (EC 1.2.7.-) Molybdopterin oxidoreductase subunit, predicted Molybdopterin oxidoreductase, iron-sulfur binding subunit (EC 1.2.7.-) Putative uncharacterized protein TTHA1760 02 Monosaccharides Unspecified_monosaccharide_transport_cluster 3-oxoacyl-[acyl-carrier protein] reductase paralog (EC 1.1.1.100) in cluster with unspecified monosaccharide transporter ACT domain protein Cell division protein FtsK FIG001621: Zinc protease FIG003568: hypothetical protein FIG007042: hypothetical protein FIG009210: peptidase, M16 family Transcriptional regulator in cluster with Zn-dependent hydrolase Transcriptional regulator in cluster with unspecified monosaccharide ABC transport system Unspecified monosaccharide ABC transport system, ATP-binding protein Unspecified monosaccharide ABC transport system, permease component 2 Unspecified monosaccharide ABC transport system, permease component Ia (FIG025991) Unspecified monosaccharide ABC transport system, permease component Ib (FIG143636) Unspecified monosaccharide ABC transport system, substrate-binding component 02 Nucleotidyl-phosphate metabolic cluster CBSS-222523.1.peg.1311 Adenylate cyclase (EC 4.6.1.1) GTP pyrophosphokinase GTP pyrophosphokinase (EC 2.7.6.5) NAD kinase (EC 2.7.1.23) Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type YjbH-like, GTP pyrophosphokinase domain putative GTP pyrophosphokinase 02 Pigment biosynthesis CBSS-176299.3.peg.235 Hypothetical sugar kinase in cluster with indigoidine synthase indA , PfkB family of kinases Indigoidine synthase A-like protein, uncharacterized enzyme involved in pigment biosynthesis Probable pyrimidine nucleoside transport protein Uncharacterized sugar kinase yeiI clustered with IndA 02 Probably GTP or GMP signaling related CBSS-176299.4.peg.1292 DNA recombination and repair protein RecO DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II GTP-binding protein Era Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) Holo-[acyl-carrier protein] synthase (EC 2.7.8.7) Mll7752 protein Ribonuclease III (EC 3.1.26.3) Signal peptidase I (EC 3.4.21.89) Signal peptidase SipW (EC 3.4.21.89), required for TasA secretion hypothetical protein NAS141_09886 02 Probably Pyrimidine biosynthesis-related CBSS-306254.1.peg.1508 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) Hypothetical protein probably associated with Carbamoyl-phosphate synthase 02 Probably Ybbk-related hypothetical membrane proteins CBSS-316057.3.peg.659 Outer membrane protein/protective antigen OMA87 Polysialic acid capsule sugar isomerase, KpsF/GutQ family Putative activity regulator of membrane protease YbbK Putative stomatin/prohibitin-family membrane protease subunit YbbK 02 Probably organic hydroperoxide resistance related hypothetical protein CBSS-269482.1.peg.1294 FIGfam005179 Homoserine kinase (EC 2.7.1.39) Organic hydroperoxide resistance protein Organic hydroperoxide resistance transcriptional regulator 02 Proteasome related clusters Proteasome_subunit_alpha_archaeal_cluster Exosome complex exonuclease 1 LSU ribosomal protein L15e LSU ribosomal protein L37Ae Predicted exosome subunit FIG055367 Probable exosome complex RNA-binding protein 1 Probable exosome complex exonuclease 2 (EC 3.1.13.-) Proteasome subunit alpha (EC 3.4.25.1), archaeal Ribonuclease P protein component 3 (EC 3.1.26.5) Shwachman-Bodian-Diamond syndrome protein 02 Protein export? CBSS-393121.3.peg.2760 ABC transporter ATP-binding protein uup Cell division protein FtsX Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) Membrane proteins related to metalloendopeptidases NLP/P60 family protein Peptidase, M23/M37 family Peptide chain release factor 2 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) Protein export cytoplasm protein SecA2 ATPase RNA helicase (TC 3.A.5.1.1) hypothetical protein BH3604 peptidoglycan lytic protein P45 02 Putative GGDEF domain protein related to agglutinin secretion CBSS-323850.3.peg.3284 ABC transporter, transmembrane region:ABC transporter:Peptidase C39, bacteriocin processing ABC-type protease exporter, membrane fusion protein (MFP) family component PrtE/AprE Agglutination protein FIGfam010717 FIGfam020323 GAF domain/GGDEF domain/EAL domain protein GGDEF and EAL domain proteins 02 Putative Isoquinoline 1-oxidoreductase subunit CBSS-314267.3.peg.390 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16) Putative Isoquinoline 1-oxidoreductase subunit, Mll3835 protein 02 Putative asociate of RNA polymerase sigma-54 factor rpoN CBSS-316057.3.peg.1308 DNA-directed RNA polymerase specialized sigma subunit, sigma24-like ECF family sigma factor ECF sigma factor ECF sigma factor PrtI, putative RNA polymerase sigma-54 factor RpoN RNA polymerase sigma-70 factor RNA polymerase sigma-70 factor, ECF family RNA polymerase sigma-70 factor, ECF subfamily RNA polymerase sigma-E factor Sigma-70 region 2:Sigma-70 region 4 Transmembrane regulator protein PrtR extracytoplasmic sigma factor EcfR macromolecule metabolism macromolecule synthesis, modification probable extracytoplasmic sigma factor EcfR putative RNA polymerase sigma factor rna synthesis, modification , dna transcription 02 Putrescine/GABA utilization cluster-temporal,to add to SSs GABA_and_putrescine_metabolism_from_cluters D-amino acid dehydrogenase small subunit (EC 1.4.99.1) GABA aminotransferase (EC 2.6.1.19) Gamma-glutamyl-GABA hydrolase Gamma-glutamyl-aminobutyraldehyde dehydrogenase (EC 1.2.1.-) Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) Psp operon transcriptional activator Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) Putrescine importer Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) Putrescine transport system permease protein PotH (TC 3.A.1.11.2) Putrescine utilization regulator 02 Pyruvate kinase associated cluster CBSS-288000.5.peg.1793 InterPro IPR001440 COGs COG0457 Pyruvate kinase (EC 2.7.1.40) UPF0335 protein R02793 bll7545 protein of unknown function DUF1036 protein of unknown function DUF1244 protein of unknown function DUF882 putative esterase 02 Recombination related cluster CBSS-198094.1.peg.4426 DNA polymerase X family Possible colicin V production protein Recombination inhibitory protein MutS2 Ribonuclease HIII (EC 3.1.26.4) 02 Related to Menaquinone-cytochrome C reductase CBSS-393130.3.peg.129 BH1670 unknown conserved protein in B. subtilis Hypothetical transmembrane protein CDS_ID OB1773 Menaquinone-cytochrome C reductase iron-sulfur subunit Menaquinone-cytochrome c reductase, cytochrome B subunit TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase 02 Ribosomal Protein L28P relates to a set of uncharacterized proteins A_Gram-positive_cluster_that_relates_ribosomal_protein_L28P_to_a_set_of_uncharacterized_proteins ATP-dependent DNA helicase RecG (EC 3.6.1.-) Dihydroxyacetone kinase family protein FIG001802: Putative alkaline-shock protein LSU ribosomal protein L28p Ribosome small subunit-stimulated GTPase EngC Ribulose-phosphate 3-epimerase (EC 5.1.3.1) Serine/threonine protein kinase PrkC, regulator of stationary phase Thiamin pyrophosphokinase (EC 2.7.6.2) 02 Ribosome-related cluster A_Gammaproteobacteria_Cluster_Relating_to_Translation 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase (EC 2.5.1.55) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) FIG002082: Protein sirB2 FIG002708: Protein SirB1 Glutamyl-tRNA reductase (EC 1.2.1.70) Methylase of polypeptide chain release factors Outer membrane lipoprotein LolB precursor Peptide chain release factor 1 Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) 02 Sarcosine oxidase CBSS-188.1.peg.6170 Sarcosine oxidase alpha subunit (EC 1.5.3.1) Sarcosine oxidase beta subunit (EC 1.5.3.1) Sarcosine oxidase delta subunit (EC 1.5.3.1) Sarcosine oxidase gamma subunit (EC 1.5.3.1) 02 Shiga toxin cluster CBSS-194948.1.peg.143 DNA packaging Lipoprotein Bor ORF B64 ORF B78 ORF B85 ORF C81-like ORF-66 Outer membrane lipoprotein Rz1 P protein Phage endolysin Phage endopeptidase Phage lysis protein S Protein NinB Protein NinE Protein NinG Putative DNA-binding protein Roi of bacteriophage BP-933W Putative antirepressor protein of cryptic prophage CP-933M Putative lysis protein S of prophage CP-933V Ren protein Shiga toxin A-chain precursor (EC 3.2.2.22) Shiga toxin I subunit B precursor Shiga-like toxin II subunit A precursor (EC 3.2.2.22) Shiga-like toxin II subunit B precursor antitermination protein Q phage replication protein P putative DNA N-6-adenine methyltransferase putative endopeptidase similar bacteriphage P22 ninH unknown protein encoded by bacteriophage BP-933W unknown protein encoded within prophage CP-933V 02 Sulfatases and sulfatase modifying factor 1 (and a hypothetical) Sulfatases_and_sulfatase_modifying_factor_1 Arylsulfatase (EC 3.1.6.1) Choline-sulfatase (EC 3.1.6.6) FIG068086: hypothetical protein Mucin-desulfating sulfatase MdsA precursor (EC 3.1.6.14) N-acetylgalactosamine 6-sulfate sulfatase (GALNS) Sulfatase Sulfatase modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1) 02 Three hypotheticals linked to lipoprotein biosynthesis CBSS-188.1.peg.9880 COG1496: Uncharacterized conserved protein COG1565: Uncharacterized conserved protein FIG018229: hypothetical protein Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-) 02 TldD cluster CBSS-354.1.peg.2917 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) FIG003879: Predicted amidohydrolase FIG005080: Possible exported protein Rod shape-determining protein MreC Rod shape-determining protein MreD Septum formation protein Maf TldD protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038) 02 Translation CBSS-243265.1.peg.198 Transcription accessory protein (S1 RNA-binding domain) Transcription elongation factor GreB CBSS-326442.4.peg.1852 ABC-type polar amino acid transport system, ATPase component Cytosine deaminase (EC 3.5.4.1) DNA-3-methyladenine glycosylase (EC 3.2.2.20) Hypothetical lysR-family transcriptional regulator YdhB LSU m5C1962 methyltransferase RlmI Putative TEGT family carrier/transport protein RNA polymerase associated protein RapA (EC 3.6.1.-) Seryl-tRNA synthetase (EC 6.1.1.11) tRNA 2-thiouridine synthesizing protein E (EC 2.8.1.-) tRNA 5-methylaminomethyl-2-thiouridine synthase TusC tRNA 5-methylaminomethyl-2-thiouridine synthase TusD tRNA(Cytosine32)-2-thiocytidine synthetase 02 Tricarboxylate transporter CBSS-49338.1.peg.459 COG5591: Uncharacterized conserved protein Putative tricarboxylic transport TctC TRAP dicarboxylate transporter, DctM subunit, unknown substrate 8 TRAP-type C4-dicarboxylate transport system, large permease component TRAP-type C4-dicarboxylate transport system, periplasmic component TRAP-type uncharacterized transport system, fused permease component Tricarboxylate transport membrane protein TctA Tricarboxylate transport membrane protein TctB tricarboxylate transport protein TctB, putative 02 Two related proteases CBSS-257314.1.peg.676 3-oxoacyl-[acyl-carrier protein] reductase paralog (EC 1.1.1.100) in cluster with unspecified monosaccharide transporter CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) Competence/damage-inducible protein CinA FIG001621: Zinc protease FIG002344: Hydrolase (HAD superfamily) FIG006542: Phosphoesterase FIG009210: peptidase, M16 family RecA protein Transcriptional regulator in cluster with unspecified monosaccharide ABC transport system Unspecified monosaccharide ABC transport system, ATP-binding protein Unspecified monosaccharide ABC transport system, permease component 2 Unspecified monosaccharide ABC transport system, permease component I Unspecified monosaccharide ABC transport system, permease component Ia (FIG025991) Unspecified monosaccharide ABC transport system, permease component Ib (FIG143636) 02 Type III secretion system, extended Type_III_secretion_systems,_extended Cell invasion protein SipD (Salmonella invasion protein D) HpaA protein HpaP protein HrcQ protein HrpB1 protein HrpB2 protein HrpB4 protein HrpD5 protein HrpD6 protein HrpF protein Invasion protein IagB precursor Invasion protein InvA Invasion protein invH precursor MxiG protein MxiH protein MxiK protein MxiN Oxygen-regulated invasion protein OrgA Oxygen-regulated invasion protein OrgB Probable ATP synthase SpaL (EC 3.6.3.14) (Invasion protein InvC) Surface presentation of antigens protein Surface presentation of antigens protein SpaM Surface presentation of antigens protein SpaN Surface presentation of antigens protein SpaN (Invasion protein InvJ) Surface presentation of antigens protein SpaO Surface presentation of antigens protein SpaP Surface presentation of antigens protein SpaQ Type III effector Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) Type III secretion chaperone protein for YopD (SycD) Type III secretion chaperone protein for YopT (SycT) Type III secretion cytoplasmic ATP synthase (EC 3.6.3.14, YscN,SpaL,MxiB,HrcN,EscN) Type III secretion cytoplasmic LcrG inhibitor (LcrV,secretion and targeting control protein, V antigen) Type III secretion cytoplasmic plug protein (LcrG) Type III secretion host injection and negative regulator protein (YopD) Type III secretion host injection protein (YopB) Type III secretion injected virulence protein (EC 3.4.22.-,YopT,cysteine protease,depolymerizes actin filaments of cytoskeleton,causes cytotoxicity) Type III secretion injected virulence protein (YopP,YopJ, induces apoptosis, prevents cytokine induction, inhibits NFkb activation) Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) Type III secretion inner membrane protein (YscQ,homologous to flagellar export components) Type III secretion inner membrane protein (YscR,SpaR,HrcR,EscR,homologous to flagellar export components) Type III secretion inner membrane protein (YscS,homologous to flagellar export components) Type III secretion inner membrane protein (YscT,HrcT,SpaR,EscT,EpaR1,homologous to flagellar export components) Type III secretion inner membrane protein (YscU,SpaS,EscU,HrcU,SsaU, homologous to flagellar export components) Type III secretion inner membrane protein SctL Type III secretion inner membrane protein SctS Type III secretion low calcium response protein (LcrR) Type III secretion negative modulator of injection (YopK,YopQ,controls size of translocator pore) Type III secretion outermembrane contact sensing protein( yopN,Yop4b,LcrE) Type III secretion outermembrane negative regulator of secretion (TyeA) Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG) Type III secretion possible injected virulence protein (YopM) Type III secretion protein (YscP) Type III secretion protein EprH Type III secretion spans bacterial envelope protein (YscO) Type III secretion system protein Type III secretion system protein BsaR Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) Type III secretion transporter lipoprotein (YscW,VirG) Unknown, probably involved in type III secretion cell invasion protein SipB hypothetical protein pYVe8081_p05 putative type III secretion protein putative type III secretion protein SycN putative type III secretion protein YscX putative type III secretion system EscC protein putative type III secretion system lipoprotein precursor EprK required for Yop secretion 02 Urate degradation CBSS-205922.3.peg.1809 Transthyretin family protein Urate oxidase (EC 1.7.3.3) Ureidoglycolate hydrolase (EC 3.5.3.19) conserved hypothetical membrane protein, paralogue of Y20848 putative uricase salvage of nucleosides and nucleotides 02 alpha-proteobacterial cluster of hypotheticals CBSS-52598.3.peg.2843 FIG003492: Threonine dehydrogenase and related Zn-dependent dehydrogenases FIG003603: membrane protein, putative FIG003620: Proteophosphoglycan precursor (Fragment) FIG017823: ATPase, MoxR family FIG139612: Possible conserved membrane protein 02 proteosome related Cluster-based_Subsystem_Grouping_Hypotheticals_-_perhaps_Proteosome_Related Bacterial proteasome-activating AAA-ATPase (PAN) FIG005453: Putative DeoR-family transcriptional regulator FIG005666: putative helicase FIG019733: possible DNA-binding protein FIG033545: PE-PGRS family protein Prokaryotic ubiquitin-like protein Pup Proteasome subunit alpha (EC 3.4.25.1), bacterial Proteasome subunit beta (EC 3.4.25.1), bacterial Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA' Pup ligase PafA, possible component of postulated heterodimer PafA-PafA' Twin-arginine translocation protein TatA Twin-arginine translocation protein TatC 02 recX and regulatory cluster CBSS-261594.1.peg.788 A/G-specific adenine glycosylase (EC 3.2.2.-) Cell division inhibitor Cysteinyl-tRNA synthetase related protein Regulatory protein RecX Transcription regulator CDS_ID OB0894 02 tRNA sulfuration CBSS-89187.3.peg.2957 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Glutathione S-transferase domain protein Glutathione S-transferase, omega (EC 2.5.1.18) Methionyl-tRNA formyltransferase (EC 2.1.2.9) Peptide deformylase (EC 3.5.1.88) hypothetical protein SKA53_09994 02 Bacterial_Cell_Division Cell division initiation protein DivIVA Cell division protein BolA Cell division protein DivIC Cell division protein FtsA Cell division protein FtsH (EC 3.4.24.-) Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) Cell division protein FtsJ Cell division protein FtsK Cell division protein FtsL Cell division protein FtsQ Cell division protein FtsW Cell division protein FtsX Cell division protein FtsZ (EC 3.4.24.-) Cell division protein MraZ Cell division topological specificity factor MinE Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) Cell division trigger factor (EC 5.2.1.8) Chromosome partitioning protein ParA Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) GTP-binding protein Era Rod shape-determining protein MreB Rod shape-determining protein MreC Rod shape-determining protein MreD Septum formation protein Maf Septum site-determining protein MinC Septum site-determining protein MinD Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1) rRNA small subunit methyltransferase H Bacterial_RNA-metabolizing_Zn-dependent_hydrolases Cell division protein FtsK Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) Ferric uptake regulation protein FUR Hydrolase (HAD superfamily) in cluster with DUF1447 Inactive homolog of metal-dependent proteases, putative molecular chaperone Metallo-beta-lactamase family protein, RNA-specific Peptide deformylase (EC 3.5.1.88) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) Protein of unknown function DUF1447 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) Transcriptional regulator in cluster with Zn-dependent hydrolase Trk system potassium uptake protein TrkA YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA Zn-dependent hydrolase, RNA-metabolising Zn-dependent hydrolase, RNA-metabolising, CPSF 100 kDa analog Zn-dependent hydrolase, RNA-metabolising, CPSF 73 kDa analog cytochrome d ubiquinol oxidase, subunit II-related protein CBSS-138119.3.peg.2719 FIG146085: 3'-to-5' oligoribonuclease A, Bacillus type Ribosome-binding factor A Translation initiation factor 2 tRNA pseudouridine synthase B (EC 4.2.1.70) CBSS-159087.4.peg.2189 FIG014574: hypothetical protein Phage T7 exclusion protein Phage T7 exclusion protein associated hypothetical protein Putative deoxyribonuclease similar to YcfH, type 4 CBSS-160492.1.peg.550 21 kDa hemolysin precursor LppC putative lipoprotein Phosphoheptose isomerase (EC 5.3.1.-) Predicted endonuclease distantly related to archaeal Holliday junction resolvase rRNA small subunit methyltransferase I CBSS-176279.3.peg.1262 Foldase clustered with pyrimidine conversion Histidine triad (HIT) nucleotide-binding protein, similarity with At5g48545 and yeast YDL125C (HNT1) Hypothetical protein SAV1839 Hypothetical protein SAV1840 CBSS-176279.3.peg.868 50S ribosomal protein acetyltransferase COG0536: GTP-binding protein Obg FIG139598: Potential ribosomal protein LSU ribosomal protein L21p LSU ribosomal protein L27p CBSS-176280.1.peg.1561 A/G-specific adenine glycosylase (EC 3.2.2.-) Acyl-CoA hydrolase (EC 3.1.2.20) Aminopeptidase S (Leu, Val, Phe, Tyr preference) (EC 3.4.11.24) FIG010063: hypothetical protein FIG133424: Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) Hypothetical protein FIG009695 Hypothetical protein SAV1869 Hypothetical protein SAV1877 Hypothetical protein YfkK Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) Ribonuclease BN (EC 3.1.-.-) Sensor histidine kinase VraS Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) Teichoic acid translocation permease protein TagG ThiJ/PfpI family protein Transcription regulator CDS_ID OB0894 Transporter associated with VraSR Two component transcriptional regulator VraR CBSS-196620.1.peg.2477 Copper ion binding protein Copper-translocating P-type ATPase (EC 3.6.3.4) D-specific D-2-hydroxyacid dehydrogenase ddh homolog (EC 1.1.1.28) Dehydrosqualene synthase (EC 2.5.1.-) Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) Ferrous iron transport protein B Hypothetical protein FIG016047 Hypothetical protein FIG016644 Maltose O-acetyltransferase (EC 2.3.1.79) N-succinyldiaminopimelate aminotransferase (EC 2.6.1.17) Putative antibiotic transport-associated protein TetR family regulatory protein CBSS-214092.1.peg.3450 FIG002208: Acetyltransferase (EC 2.3.1.-) FIG137864: putative endonuclease containing a URI domain FIG138517: Putative lipid carrier protein FIG139552: Putative protease FIG139928: Putative protease CBSS-224911.1.peg.435 Carboxyl-terminal protease (EC 3.4.21.102) FIG000735: Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) Peptidase M23B precursor Possible divergent polysaccharide deacetylase CBSS-228410.1.peg.134 DNA polymerase III epsilon subunit (EC 2.7.7.7) FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) Ribonuclease HI (EC 3.1.26.4) CBSS-235.1.peg.567 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Amino acid regulated cytosolic protein C4-type zinc finger protein, DksA/TraR family Dihydroneopterin aldolase (EC 4.1.2.25) Dihydropteroate synthase (EC 2.5.1.15) GTP-binding protein Mlr0777 protein Mlr0789 protein Phosphohistidine phosphatase SixA CBSS-243277.1.peg.4359 FIG094199: Fumarylacetoacetate hydrolase Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) Protein YcgL YcgN (Fragment) CBSS-251221.1.peg.1863 Outer membrane protein/protective antigen OMA87 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (EC 3.5.1.-) CBSS-257314.1.peg.752 Acetate kinase (EC 2.7.2.1) Adenine-specific methyltransferase (EC 2.1.1.72) Thiol peroxidase, Tpx-type (EC 1.11.1.15) CBSS-261594.1.peg.2640 FAD-dependent pyridine nucleotide-disulphide oxidoreductase, GBAA2537 homolog Hypothetical protein, GBAA2540 homolog Hypothetical protein, sulfurtransferase domain Metal-dependent hydrolase COG0491 with rhodanese-homology domain (RHOD) Protein of unknown function DUF156 Protein of unknown function DUF81, SAV0084 homolog Putative phosphoesterase, GBAA2539 homolog CBSS-266117.6.peg.2476 Guanine deaminase (EC 3.5.4.3) Regulator of polyketide synthase expression Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Xanthine dehydrogenase iron-sulfur subunit (EC 1.17.1.4) Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4) Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4) Xanthine/uracil/thiamine/ascorbate permease family protein hypothetical protein SC6C5.04c CBSS-269801.1.peg.1715 FIG007079: UPF0348 protein family FIGfam003972: membrane protein Lon-like protease with PDZ domain Phosphopantetheine adenylyltransferase (EC 2.7.7.3) Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) Serine protease (EC 3.4.21.-) CBSS-269801.1.peg.1725 2-dehydropantoate 2-reductase (EC 1.1.1.169) 5-nucleotidase SurE (EC 3.1.3.5) BH2577 unknown conserved protein in B. subtilis Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) Penicillin-binding protein 2 (PBP-2) Penicillin-binding protein 2B Penicillin-binding protein 3 S-adenosyl-methyltransferase MraW (EC 2.1.1.-) Stage V sporulation protein D (Sporulation-specific penicillin-binding protein) Uncharacterized N-acetyltransferase BT9727_3663 (EC 2.3.1.-) putative patatin-like phospholipase CBSS-281090.3.peg.464 Alanyl-tRNA synthetase (EC 6.1.1.7) FIG004453: protein YceG like Putative Holliday junction resolvase (EC 3.1.-.-) Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) CBSS-288681.3.peg.1039 Conserved protein YqhG Superfamily II DNA/RNA helicases, SNF2 family CBSS-290633.1.peg.1906 GTP-binding protein EngA Mlr7403 protein Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) CBSS-291331.3.peg.3674 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) Cyclopropane-fatty-acyl-phospholipid synthase-like protein, clusters with FIG005069 FIG001568: Amine oxidase, flavin-containing FIG001571: Hypothetical protein FIG002994: Putative transcriptional regulator FIG005069: Hypothetical protein FIG026291: Hypothetical periplasmic protein FIG033155: Hypothetical protein FIG086212: Putative lipoprotein FIG097052: Sugar transporter Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase Transcriptional regulator, MerR family, associated with photolyase CBSS-296591.1.peg.2330 Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-) Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) NAD-dependent epimerase/dehydratase NAD-dependent epimerase/dehydratase family protein Nucleoside-diphosphate sugar epimerase/dehydratase Nucleoside-diphosphate-sugar epimerases Nucleotide sugar epimerase Putative glycosyltransferase UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) UDP-glucose 4-epimerase (EC 5.1.3.2) UDP-glucuronate 5'-epimerase (EC 5.1.3.12) dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) CBSS-312309.3.peg.1965 Methionine aminopeptidase (EC 3.4.11.18) SSU ribosomal protein S2p (SAe) Translation elongation factor Ts Uridylate kinase (EC 2.7.4.-) [Protein-PII] uridylyltransferase (EC 2.7.7.59) CBSS-314269.3.peg.1840 Carbon monoxide dehydrogenase F protein Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 ) Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) parolog without usual motifs Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) without typical motifs Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2) Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) Carbon-monoxide dehydrogenase form II, large subunit (EC 1.2.99.2) Transcription regulator in CO-DH cluster Uncharacterized MobA-related protein carbon monoxide dehydrogenase D protein carbon monoxide dehydrogenase E protein carbon monoxide dehydrogenase operon C protein CBSS-316057.3.peg.3521 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) Large exoproteins involved in heme utilization or adhesion Thiol peroxidase, Bcp-type (EC 1.11.1.15) CBSS-316057.3.peg.563 Cytochrome c oxidase polypeptide II (EC 1.9.3.1) Cytochrome c oxidase polypeptide III (EC 1.9.3.1) Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB TldD protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038) conserved hypothetical protein in cyt c oxidase gene clusters CBSS-316273.3.peg.227 Alpha-2-macroglobulin Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C Protein SseB Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) CBSS-316273.3.peg.2378 FIG006126: DNA helicase, restriction/modification system component YeeB FIG045374: Type II restriction enzyme, methylase subunit YeeA YeeC-like protein CBSS-316273.3.peg.2709 FIG034376: Hypothetical protein FIG036757: Plasmid-related protein FIG041301: Hypothetical protein FIG046709: Hypothetical protein FIG049434: Periplasmic protein TonB, links inner and outer membranes FIG076210: Hypothetical protein FIG076676: Hypothetical protein Superfamily II DNA/RNA helicases, SNF2 family CBSS-316273.3.peg.448 FIG017823: ATPase, MoxR family FIG033680: Hypothetical protein FIG037995: Hypothetical protein FIG042594: DUF1550 domain-containing protein FIG045085: Hypothetical protein FIG048626: Hypothetical protein TldD family protein, Actinobacterial subgroup TldE/PmbA family protein, Actinobacterial subgroup CBSS-316273.3.peg.922 FIG034602: Probable transmembrane protein FIG035830: Two-component system regulatory protein FIG037127: Two-component system sensor protein FIG086515: Hypothetical protein Integral membrane protein CcmA involved in cell shape determination probable iron binding protein from the HesB_IscA_SufA family CBSS-316279.3.peg.746 FIG017608: hypothetical membrane protein, specific for cyanobacteria Hypothetical protein of L-Asparaginase type 2-like superfamily Iojap protein Uncharacterized membrane protein Ycf36 CBSS-316407.3.peg.2816 Arginine exporter protein ArgO Lysine efflux permease Protein involved in stability of MscS mechanosensitive channel Protein of unknown function DUF541 CBSS-320372.3.peg.6046 Aspartate carbamoyltransferase (EC 2.1.3.2) Glutathione synthetase (EC 6.3.2.3) Ornithine carbamoyltransferase (EC 2.1.3.3) Putative Holliday junction resolvase (EC 3.1.-.-) UPF0301 protein YqgE CBSS-323097.3.peg.2594 FIG003307: hypothetical protein FIG004453: protein YceG like Guanylate kinase (EC 2.7.4.8) Protein YicC CBSS-342610.3.peg.1794 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) ADP-ribose pyrophosphatase (EC 3.6.1.13) Putative esterase, FIGfam005057 Topoisomerase IV subunit B (EC 5.99.1.-) CBSS-345072.3.peg.1318 BatA (Bacteroides aerotolerance operon) BatB BatC BatD BatE MoxR-like ATPase in aerotolerance operon TPR domain protein in aerotolerance operon hypothetical protein PA3071 CBSS-350688.3.peg.1509 COG0779: clustered with transcription termination protein NusA COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination DNA polymerase III alpha subunit (EC 2.7.7.7) Dipicolinate synthase subunit A (EC 4.2.1.52) FIG007013: polysaccharide deacetylase, putative FIG007697: hypothetical protein FIG007959: peptidase, M16 family FMN adenylyltransferase (EC 2.7.7.2) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) Riboflavin kinase (EC 2.7.1.26) Ribosome-binding factor A SSU ribosomal protein S15p (S13e) Transcription termination protein NusA Translation initiation factor 2 YlxP-like protein ribosomal protein L7Ae family protein tRNA pseudouridine synthase B (EC 4.2.1.70) CBSS-370552.3.peg.1240 FIG006988: Lipase/Acylhydrolase with GDSL-like motif Hypothetical protein DUF194, DegV family YfaA CBSS-393121.3.peg.1913 (S)-3-O-geranylgeranylglyceryl phosphate synthase ATP-dependent DNA helicase UvrD/PcrA ATP-dependent DNA helicase pcrA (EC 3.6.1.-) DNA ligase (EC 6.5.1.2) His repressor Lin1875 protein CBSS-393124.3.peg.2657 ADA regulatory protein Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) Probable carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) CBSS-393131.3.peg.612 Putative metallopeptidase (Zinc) SprT family Transcription accessory protein (S1 RNA-binding domain) CBSS-393133.3.peg.2787 Thymidylate kinase (EC 2.7.4.9) protein from nitrogen regulatory protein P-II (GLNB) family, ortholog YAAQ B. subtilis CBSS-562.2.peg.5158_SK3_including AroM protein Cytoplasmic protein YaiE DNA recombination-dependent growth factor C Protein YaiA Protein YaiI Protein YkiA Shikimate kinase III (EC 2.7.1.71) CBSS-56780.10.peg.1536 FIG000233: metal-dependent hydrolase Magnesium and cobalt efflux protein CorC Membrane protein containing HD superfamily hydrolase domain, YQFF ortholog Phosphate starvation-inducible ATPase PhoH with RNA binding motif Phosphate starvation-inducible protein PhoH, predicted ATPase CBSS-630.2.peg.3360 HAM1-like protein Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) Pyrroline-5-carboxylate reductase (EC 1.5.1.2) Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB Similar to coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) UPF0235 protein VC0458 CBSS-83332.1.peg.3803 Antigen 85-A precursor (85A) (Antigen 85 complex A) (Ag85A) (Mycolyl transferase 85A) (EC 2.3.1.-) Antigen 85-B precursor (85B) (Extracellular alpha-antigen) (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B) (EC 2.3.1.-) Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-) Probable acyl-CoA dehydrogenase fadE35 (EC 1.3.99.-) Probable polyketide synthase, similar to many. e.g. gp|M63676|SERERYAA_1 S.erythraea first ORF of eryA gene, involved in complex polyketide formation in erythromycin biosynthesis. Propionyl-CoA carboxylase beta chain (EC 6.4.1.3) Transposase for insertion sequence element IS1557 fatty-acid-CoA ligase FadD32 hypothetical protein Rv3802c hypothetical protein Rv3805c CBSS-83333.1.peg.946 Cell division inhibitor DNA helicase IV DNA transformation protein TfoX Helicase IV (EC 3.6.1.-) Inner membrane protein YccF LSU m5C1962 methyltransferase RlmI Methylglyoxal synthase (EC 4.2.3.3) Putative efflux (PET) family inner membrane protein YccS Succinyl-CoA synthetase, alpha subunit-related enzymes UPF0319 protein YccT precursor hemimethylated DNA binding protein YccV CBSS-87626.3.peg.3639 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (EC 1.14.13.-) 2-octaprenyl-6-methoxyphenol hydroxylase (EC 1.14.13.-) Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) FIG001590: Putative conserved exported protein precursor Xaa-Pro aminopeptidase (EC 3.4.11.9) Cell_division-ribosomal_stress_proteins_cluster Cell division protein DivIC Cell division protein FtsH (EC 3.4.24.-) Hypothetical protein, FIG12300 and FIG043029 fams Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) Low temperature requirement B protein Peptidyl-tRNA hydrolase (EC 3.1.1.29) Peptidyl-tRNA hydrolase, archaeal type (EC 3.1.1.29) RNA binding protein, contains ribosomal protein S1 domain Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) S1 RNA binding domain protein S4-domain-containing heat shock protein SSU ribosomal protein S1p Spore cortex biosynthesis protein Transcription accessory protein (S1 RNA-binding domain) Transcription-repair coupling factor Transcription-repair coupling factor fragment a forespore shell protein cell-division initiation protein tRNA(Ile)-lysidine synthetase Conserved_cluster_around_acetyltransferase_YpeA_in_Enterobacteria Acetyltransferase YpeA Inner membrane protein YfeZ Predicted iron-dependent peroxidase, Dyp-type family Predicted outer membrane lipoprotein YfeY Conserved_cluster_in_Enterobacteriaceae_downstream_from_YqjA,_a_DedA_family_protein DedA family inner membrane protein YqjA Glutathione S-transferase, omega (EC 2.5.1.18) Inner membrane protein YhaH Inner membrane protein YhaI Inner membrane protein YqjE Inner membrane protein YqjF Inner membrane protein YqjK LysR-family transcriptional regulator YhaJ Periplasmic protein YqjC Pirin-like protein YhaK Uncharacterized membrane protein YqjD Uncharacterized protein YhaL Uncharacterized protein YqjB Conserved_gene_cluster_associated_with_Met-tRNA_formyltransferase 16S rRNA m(5)C 967 methyltransferase (EC 2.1.1.-) 50S ribosomal subunit maturation GTPase RbgA (B. subtilis YlqF) Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) DNA topoisomerase I (EC 5.99.1.2) GTP-sensing transcriptional pleiotropic repressor codY Helicase PriA essential for oriC/DnaA-independent DNA replication Hydrolase (HAD superfamily) in cluster with DUF1447 Inactive homolog of metal-dependent proteases, putative molecular chaperone Methionyl-tRNA formyltransferase (EC 2.1.2.9) Peptide deformylase (EC 3.5.1.88) Protein of unknown function DUF1447 Protein of unknown function Smg Protein serine/threonine phosphatase PrpC, regulation of stationary phase Ribonuclease HII (EC 3.1.26.4) Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) Ribulose-phosphate 3-epimerase (EC 5.1.3.1) Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake Serine/threonine protein kinase PrkC, regulator of stationary phase Serine/threonine protein kinase PrkC, regulator of stationary phase, short form Similar to C-terminal Zn-finger domain of DNA topoisomerase I Trk system potassium uptake protein TrkA Uncharacterized protein with LysM domain, COG1652 YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA Zn-dependent hydrolase, RNA-metabolising cytochrome d ubiquinol oxidase, subunit II-related protein tRNA:m(5)U-54 MTase gid EC49-61 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) ApaG protein Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) DNA polymerase II (EC 2.7.7.7) Dihydrofolate reductase (EC 1.5.1.3) Dimethyladenosine transferase (EC 2.1.1.-) DnaJ-like protein DjlA Organic solvent tolerance protein precursor RNA polymerase associated protein RapA (EC 3.6.1.-) Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) EC699-706 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) Deoxyribodipyrimidine photolyase (EC 4.1.99.3) Deoxyribodipyrimidine photolyase, type II (EC 4.1.99.3) Di/tripeptide permease YbgH Endonuclease VIII FIG042796: Hypothetical protein FIG143828: Hypothetical protein YbgA Lactam utilization protein LamB KH_domain_RNA_binding_protein_YlqC 16S rRNA processing protein RimM KH domain RNA binding protein YlqC SSU ribosomal protein S16p LMPTP_YfkJ_cluster Hypothetical protein YfkI Hypothetical protein YfkK Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) Ribonuclease BN (EC 3.1.-.-) LMPTP_YwlE_cluster Hypothetical protein ywlG Hypothetical transmembrane protein ywlD Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) Peptide chain release factor 1 Ribose 5-phosphate isomerase B (EC 5.3.1.6) Serine hydroxymethyltransferase (EC 2.1.2.1) Uracil phosphoribosyltransferase (EC 2.4.2.9) YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA NusA-TFII_Cluster COG0779: clustered with transcription termination protein NusA COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination Ribosome-binding factor A Transcription termination protein NusA Translation initiation factor 2 YlxP-like protein ribosomal protein L7Ae family protein PA0057_cluster LysR-family transcriptional regulator clustered with PA0057 Metallo-beta-lactamase superfamily protein PA0057 Thioredoxin-like protein clustered with PA0057 Putative_hemin_transporter Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-) Hemin ABC transporter, permease protein Peroxide stress regulator PerR, FUR family Phosphate starvation-inducible ATPase PhoH with RNA binding motif Putative Heme-regulated two-component response regulator Putative hemin-binding lipoprotein Putative hemine transporter ATP-binding subunit iron-regulated outer membrane protein FrpB probable Mg2+ transport protein puatative hemin transporter subunit putative hemin permease Putative_sulfate_assimilation_cluster Alkanesulfonates-binding protein Putative reductase (alkanesulfonate metabolism) Spore_Coat Inner spore coat protein D Inner spore coat protein H Major transcriptional regulator of spore coat formation GerE Outer spore coat protein E Polypeptide composition of the spore coat protein CotJB Polypeptide composition of the spore coat protein CotJC Polypeptide composition of the spore coat; required for the assembly of CotJC Small, acid-soluble spore protein O Small, acid-soluble spore protein P Spore coat protein A Spore coat protein B Spore coat protein C Spore coat protein F Spore coat protein G Spore coat protein M Spore coat protein S Spore coat protein T precursor Spore coat protein V Spore coat protein W Spore coat protein X Spore coat protein Y Spore coat protein Z Stage IV sporulation protein A Stage VI sporulation protein D Staphylococcus_aureus_hypothetical_repetitive_gene_loci Alcohol dehydrogenase (EC 1.1.1.1) Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1) Diphosphomevalonate decarboxylase (EC 4.1.1.33) Mercuric reductase (EC 1.16.1.1) Oxidoreductase ion channel Phosphomevalonate kinase (EC 2.7.4.2) Probable pyridine nucleotide-disulfide oxidoreductase YkgC Putative Dihydrolipoamide dehydrogenase (EC 1.8.1.4) hypothetical fig|282458.1.peg.572 homolog hypothetical fig|282458.1.peg.573 homolog hypothetical fig|282458.1.peg.578 homolog hypothetical fig|282458.1.peg.579 homolog hypothetical fig|282458.1.peg.581 homolog hypothetical fig|282458.1.peg.583 homolog hypothetical fig|418127.4.peg.560 homolog repetative hypothetical protein , fig|282458.1.peg.574 homolog USS-DB-1 Hypothetical protein USSDB1A Hypothetical protein USSDB1E Sugar ABC transporter, periplasmic sugar-binding protein USSDB1B Sugar ABC transporter, sugar permease protein 1 USSDB1C Sugar ABC transporter, sugar permease protein 2 USSDB1D USS-DB-2 Efflux system membrane fusion protein [USSDB2C] Multidrug efflux transporter [USSDB2D] Outer membrane protein [USSDB2E] Response regulator, ompR family [USSDB2A] Two-component system sensor protein [USSDB2B] USS-DB-4 Efflux system membrane fusion protein [USSDB4B] Multidrug efflux transporter [USSDB4C] Transcriptional regulator, TetR (AcrR) family [USSDB4A] USS-DB-6 ABC transporter ATP-binding protein USSDB6B ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A Membrane lipoprotein lipid attachment site containing protein USSDB6D USS-DB-7 ClpB protein Outer membrane protein ImpK/VasF, OmpA/MotB domain Protein ImpG/VasA Protein of avirulence locus ImpE Protein phosphatase ImpM Putative cytoplasmic protein USSDB7A Uncharacterized protein ImpA Uncharacterized protein ImpB Uncharacterized protein ImpC Uncharacterized protein ImpD Uncharacterized protein ImpF Uncharacterized protein ImpH/VasB Uncharacterized protein ImpI/VasC Uncharacterized protein ImpJ/VasE Uncharacterized protein similar to VCA0109 VgrG protein Yfa_cluster Competence/damage-inducible protein CinA Inner membrane transport protein YfaV Pyrimidine deoxynucleoside triphosphate (dYTP) pyrophosphohydrolase YfoO Uncharacterized protein YfaD Uncharacterized protein YfaU Uncharacterized protein YfaW Uncharacterized protein YfaZ precursor Uncharacterized transcriptional regulator YfaX, HTH-type 01 Cofactors, Vitamins, Prosthetic Groups, Pigments 02 Biotin Biotin_biosynthesis 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 8-amino-7-oxononanoate synthase (EC 2.3.1.47) ATPase component BioM of energizing module of biotin ECF transporter Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) Biotin operon repressor Biotin synthase (EC 2.8.1.6) Biotin synthesis protein bioC Biotin synthesis protein bioG Biotin synthesis protein bioH Biotin synthesis protein bioK Biotin synthesis protein bioZ Biotin-protein ligase (EC 6.3.4.15) Dethiobiotin synthetase (EC 6.3.3.3) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Pimeloyl-CoA synthase (EC 6.2.1.14) Predicted biotin repressor from TetR family Substrate-specific component BioY of biotin ECF transporter Transmembrane component BioN of energizing module of biotin ECF transporter predicted biotin regulatory protein BioR (GntR family) 02 Coenzyme A Coenzyme_A_Biosynthesis 2-dehydropantoate 2-reductase (EC 1.1.1.169) 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) Aspartate 1-decarboxylase (EC 4.1.1.11) Dephospho-CoA kinase (EC 2.7.1.24) Dephospho-CoA kinase archaeal, predicted (EC 2.7.1.24) Ketol-acid reductoisomerase (EC 1.1.1.86) Pantoate kinase, archaeal (EC 2.7.1.-) Pantoate--beta-alanine ligase (EC 6.3.2.1) Pantothenate kinase (EC 2.7.1.33) Pantothenate kinase type II, eukaryotic (EC 2.7.1.33) Pantothenate kinase type III, CoaX-like (EC 2.7.1.33) Pantothenate:Na+ symporter (TC 2.A.21.1.1) Phosphopantetheine adenylyltransferase (EC 2.7.7.3) Phosphopantetheine adenylyltransferase, type II eukaryotic (EC 2.7.7.3) Phosphopantothenate synthetase, archaeal Phosphopantothenoylcysteine decarboxylase (EC 4.1.1.36) Phosphopantothenoylcysteine synthetase (EC 6.3.2.5) Substrate-specific component PanT of predicted pantothenate ECF transporter 02 Coenzyme B Coenzyme_B_synthesis Coenzyme B synthesis from 2-oxoglutarate: steps 1, 6, and 10 Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 [large subunit] Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 [small subunit] Coenzyme B synthesis from 2-oxoglutarate: steps 5, 9, and 13 02 Coenzyme F420 Coenzyme_F420_synthesis 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 Coenzyme F420-0:L-glutamate ligase Coenzyme F420-1:L-glutamate ligase Coenzyme gamma-F420-2:L-glutamate ligase Lactyl (2) diphospho-(5')guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase putative L-glutamate ligase 02 Coenzyme M coenzyme_M_biosynthesis 2-phosphosulfolactate phosphatase (EC 3.1.3.71) Coenzyme M synthase L-sulfolactate dehydrogenase (EC 1.1.1.272) Phosphosulfolactate synthase (EC 4.4.1.19) Sulfoethylcysteine synthase Sulfomethyl thiazolidine synthase Sulfopyruvate decarboxylase - alpha subunit (EC 4.1.1.79) Sulfopyruvate decarboxylase - beta subunit (EC 4.1.1.79) 02 Folate and pterines 5-FCL-like_protein 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 5-FCL-like protein 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Alcohol dehydrogenase (EC 1.1.1.1) Alternative dihydrofolate reductase 2 Butyryl-CoA dehydrogenase (EC 1.3.99.2) Dihydrofolate reductase (EC 1.5.1.3) Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) Dihydrolipoamide dehydrogenase (EC 1.8.1.4) Formate--tetrahydrofolate ligase (EC 6.3.4.3) Formiminotetrahydrofolate cyclodeaminase (EC 4.3.1.4) Formyltetrahydrofolate deformylase (EC 3.5.1.10) Glutamate formiminotransferase (EC 2.1.2.5) H4MPt-dependent SHMT Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) MTHFR (MetF)-like Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) Phosphomethylpyrimidine kinase (EC 2.7.4.7) Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Pyruvate dehydrogenase E1 component (EC 1.2.4.1) Serine hydroxymethyltransferase (EC 2.1.2.1) Substrate-specific component ThiW of predicted thiazole ECF transporter Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Thiamin-phosphate synthase ThiN (EC 2.5.1.3) Thiaminase II (EC 3.5.99.2) Thiamine kinase (EC 2.7.1.89) Thiamine-monophosphate kinase (EC 2.7.4.16) YjbQ (alternate ThiE) YlmB Folate_Biosynthesis 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 5-nucleotidase SurE (EC 3.1.3.5) 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) ATPase component of general energizing module of ECF transporters Alternative Folylglutamate Synthase Alternative dihydrofolate reductase 2 Alternative dihydrofolate reductase 3 Aminodeoxychorismate lyase (EC 4.1.3.38) COG0488: ATPase components of ABC transporters with duplicated ATPase domains Dihydrofolate reductase (EC 1.5.1.3) Dihydrofolate synthase (EC 6.3.2.12) Dihydroneopterin aldolase (EC 4.1.2.25) Dihydroneopterin triphosphate epimerase Dihydroneopterin triphosphate pyrophosphohydolase Dihydroneopterin triphosphate pyrophosphohydolase type 2 Dihydropteroate synthase (EC 2.5.1.15) FolM Alternative dihydrofolate reductase 1 Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) Folate transporter 3 Folylpolyglutamate synthase (EC 6.3.2.17) Formate--tetrahydrofolate ligase (EC 6.3.4.3) GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase I (EC 3.5.4.16) type 2 Methionyl-tRNA formyltransferase (EC 2.1.2.9) Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Non functional Dihydropteroate synthase 2 Nucleoside triphosphate pyrophosphohydrolase MazG Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) PqqC-like protein Putative DHNTP pyrophosphatase Related to Dihydropteroate synthase Serine hydroxymethyltransferase (EC 2.1.2.1) Substrate-specific component FolT of folate ECF transporter Thymidine kinase (EC 2.7.1.21) Thymidylate synthase (EC 2.1.1.45) Thymidylate synthase thyX (EC 2.1.1.-) Transaldolase (EC 2.2.1.2) Transmembrane component of general energizing module of ECF transporters Xanthosine/inosine triphosphate pyrophosphatase alternate gene name: yzbB Methanopterin_biosynthesis2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) 7,8 dihydropteroate synthase (methanopterin) 7,8-dihydronepterin 2' :3'-cyclicphosphate hydrolase Archaeal flavoprotein COG1036 COG1548 family protein COG1821 family protein D-arabino-3-hexulose 6-phosphate formaldehyde lyase / 6-phospho-3-hexuloisomerase DUF447 family protein Dihydroneopterin aldolase (EC 4.1.2.25) Dihydroneopterin aldolase (methanopterin) Dihydroneopterin monophosphate dephosphorylase Folate biosynthesis, PTPS-III GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase I (EC 3.5.4.16) type 2 GTP cyclohydrolase III (EC 3.5.4.29) Gamma-F420-2:alpha-L-glutamate ligase cofF Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase related protein Queuosine biosynthesis QueD, PTPS-I Related to Dihydropteroate synthase Triaminopyrimidine triphosphate phosphomutase Triphosphoribosyl-dephospho-CoA synthetase beta-ribofuranosylaminobenzene 5'-phosphate synthase delta 1-pyrroline-5-carboxylate synthetase duf556 family protein Molybdenum_cofactor_biosynthesis DNA-binding domain of ModE GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase II (EC 3.5.4.25) Molybdate-binding domain of ModE Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) Molybdenum cofactor biosynthesis protein MoaA Molybdenum cofactor biosynthesis protein MoaB Molybdenum cofactor biosynthesis protein MoaC Molybdenum cofactor biosynthesis protein MoaD Molybdenum cofactor biosynthesis protein MoaE Molybdenum transport ATP-binding protein ModC (TC 3.A.1.8.1) Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) Molybdenum transport system protein ModD Molybdopterin binding domain MoeA-like Molybdopterin biosynthesis Mog protein, molybdochelatase Molybdopterin biosynthesis enzyme Molybdopterin biosynthesis protein MoeA Molybdopterin biosynthesis protein MoeB Molybdopterin-guanine dinucleotide biosynthesis protein MobA Molybdopterin-guanine dinucleotide biosynthesis protein MobB Periplasmic molybdate-binding domain Protein co-occuring with molybdenum cofactor biosynthesis protein B Pterin_biosynthesis 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-) Aldo-keto reductase family 1, member C3 (EC 1.1.1.-) Dihydropteridine reductase (EC 1.5.1.34) GTP cyclohydrolase I (EC 3.5.4.16) type 1 Phenylalanine-4-hydroxylase (EC 1.14.16.1) Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Sepiapterin reductase (EC 1.1.1.153) UDP-glucose:tetrahydrobiopterin glucosyltransferase [EC:2.4.1.-] Pterin_carbinolamine_dehydratase 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) Aromatic-amino-acid aminotransferase (EC 2.6.1.57) Fumarylacetoacetase (EC 3.7.1.2) Fumarylacetoacetate hydrolase family protein Homogentisate 1,2-dioxygenase (EC 1.13.11.5) Maleylacetoacetate isomerase (EC 5.2.1.2) Maleylacetoacetate isomerase (EC 5.2.1.2) Phenylalanine-4-hydroxylase (EC 1.14.16.1) Phenylalanine-4-hydroxylase (EC 1.14.16.1) - Long Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Pterin-4-alpha-carbinolamine dehydratase-like Pterin_metabolism 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) GTP cyclohydrolase I (EC 3.5.4.16) type 1 Phenylalanine-4-hydroxylase (EC 1.14.16.1) Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Pterin_metabolism_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) Acetoacetyl-CoA synthetase (EC 6.2.1.16) Aromatic-amino-acid aminotransferase (EC 2.6.1.57) COG1565: Uncharacterized conserved protein COGs COG3146 Dihydroneopterin aldolase (EC 4.1.2.25) Dihydroneopterin triphosphate epimerase Dihydropteroate synthase (EC 2.5.1.15) FolM Alternative dihydrofolate reductase 1 Fumarylacetoacetase (EC 3.7.1.2) Fumarylacetoacetate hydrolase family protein GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase I (EC 3.5.4.16) type 2 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) Maleylacetoacetate isomerase (EC 5.2.1.2) Nitric oxide synthase oxygenase (EC 1.-.-.-) Phenylalanine-4-hydroxylase (EC 1.14.16.1) Phenylalanine-4-hydroxylase (EC 1.14.16.1) - Long Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) Pterin-4-alpha-carbinolamine dehydratase-like Related to Dihydropteroate synthase Sepiapterin reductase (EC 1.1.1.153) methanopterin_biosynthesis 6-hydroxymethyl-dihydropterin pyrophosphokinase 7,8 dihydropteroate synthase (methanopterin) 7,8-dihydronepterin 2' :3'-cyclicphosphate hydrolase Dihydroneopterin aldolase (methanopterin) Dihydroneopterin monophosphate dephosphorylase GTP cyclohydrolase III (methanopterin) Triaminopyrimidine triphosphate phosphomutase beta-ribofuranosylaminobenzene 5'-phosphate synthase p-Aminobenzoyl-Glutamate_Utilization Aminobenzoyl-glutamate transport protein Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit B Regulatory protein (induces abgABT, used to catabolize p-aminobenzoyl-glutamate) 02 Lipoic acid Lipoic_acid_metabolism Lipoate synthase Lipoate synthase, cyanobacterial paralog Lipoate-protein ligase A Lipoate-protein ligase A type 2 Lipoate-protein ligase A, C-terminal 70 percent Lipoate-protein ligase A, N-terminal 30 percent Octanoate-[acyl-carrier-protein]-protein-N-octanoyltransferase Proposed lipoate regulatory protein YbeD 02 NAD and NADP NAD_and_NADP_cofactor_biosynthesis_global 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) ADP-ribose pyrophosphatase (EC 3.6.1.13) Amidases related to nicotinamidase C-terminal domain of CinA type S C-terminal domain of CinA type S homolog Glutamine amidotransferase chain of NAD synthetase Indoleamine 2,3-dioxygenase (EC 1.13.11.52) Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis Kynureninase (EC 3.7.1.3) Kynurenine 3-monooxygenase (EC 1.14.13.9) Kynurenine formamidase (EC 3.5.1.9) Kynurenine formamidase, bacterial (EC 3.5.1.9) Kynurenine formamidase, yeast-type BNA7 (EC 3.5.1.9) L-Aspartate dehydrogenase (EC 1.4.1.21) L-aspartate oxidase (EC 1.4.3.16) N-Ribosylnicotinamide phosphorylase (EC 2.4.2.1) NAD kinase (EC 2.7.1.23) NAD pyrophosphatase, periplasmic (EC 3.6.1.22) NAD synthetase (EC 6.3.1.5) NAD transporter of endosymbionts, possible NMN 5'-nucleotidase, extracellular (EC 3.1.3.5) NMN phosphatase (EC 3.1.3.5) NMN synthetase (EC 6.3.1.-) NadR transcriptional regulator Niacin transporter NiaP Niacin transporter in yeast, DAL5 family Nicotinamidase (EC 3.5.1.19) Nicotinamidase family protein YcaC Nicotinamidase/isochorismatase family protein Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) Nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), eukaryotic PNAT family Nicotinamide-nucleotide adenylyltransferase, NadM family (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) Nicotinate phosphoribosyltransferase (EC 2.4.2.11) Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18), eukaryotic PNAT family Nicotinate-nucleotide adenylyltransferase, NadM family (EC 2.7.7.18) Nicotine adenine dinucleotide glycohydrolase (NADGH) (EC 3.2.2.5) Nudix-related transcriptional regulator NrtR Predicted N-ribosylNicotinamide CRP-like regulator Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) Quinolinate synthetase (EC 2.5.1.72) Ribosyl nicotinamide transporter, PnuC-like Ribosylnicotinamide kinase (EC 2.7.1.22) Ribosylnicotinamide kinase, eukaryotic (EC 2.7.1.22) Substrate-specific component NiaX of predicted niacin ECF transporter Transcriptional repressor for NAD biosynthesis in gram-positives Tryptophan 2,3-dioxygenase (EC 1.13.11.11) NAD_consumption Actin-ADP-ribosyltransferase, toxin SpvB DNA ligase (EC 6.5.1.2) NAD-dependent protein deacetylase of SIR2 family NAD_regulation Aspartate dehydrogenase [same functional role as] (EC 1.4.3.16) Core component Spy1425 of predicted NAD-regulated ECF transporter for niacin Hypothetical Nudix-like regulator L-aspartate oxidase (EC 1.4.3.16) NAD synthetase (EC 6.3.1.5) NadR transcriptional regulator Niacin transporter NiaP Nicotinamidase (EC 3.5.1.19) Nicotinamide phosphoribosyltransferase (EC 2.4.2.12) Nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase, NadM family (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) Nicotinate phosphoribosyltransferase (EC 2.4.2.11) Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) Nudix-related transcriptional regulator NrtR Predicted NAD regulator in Alphaproteobacteria Predicted nicotinate-regulated transporter BH3254 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) Quinolinate synthetase (EC 2.5.1.72) Ribosyl nicotinamide transporter, PnuC-like Transcriptional repressor for NAD biosynthesis in gram-positives 02 Pyridoxine Pyridoxin(Vitamin_B6)_Degradation_Pathway 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (EC 1.14.12.4) 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase (EC 4.1.1.51) 4-pyridoxic acid dehydrogenase 4-pyridoxolactonase (EC 3.1.1.27) Pyridoxal 4-dehydrogenase (EC 1.1.1.107) Pyridoxine 4-oxidase (EC 1.1.3.12) Pyridoxin_(Vitamin_B6)_Biosynthesis 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Phosphoserine aminotransferase (EC 2.6.1.52) Predicted transcriptional regulator of pyridoxine metabolism Pyridoxal kinase (EC 2.7.1.35) Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit (EC 2.4.2.-) Pyridoxine biosynthesis glutamine amidotransferase, synthase subunit (EC 2.4.2.-) Substrate-specific component PdxT of predicted pyridoxine ECF transporter 02 Quinone cofactors Coenzyme_PQQ_synthesis Coenzyme PQQ synthesis protein A Coenzyme PQQ synthesis protein B Coenzyme PQQ synthesis protein C Coenzyme PQQ synthesis protein D Coenzyme PQQ synthesis protein E Coenzyme PQQ synthesis protein F (EC 3.4.99.-) Paralog of coenzyme PQQ synthesis protein C Similar to coenzyme PQQ synthesis protein B Menaquinone_Biosynthesis_via_Futalosine_--_gjo 3-polyprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) 4-hydroxybenzoate polyprenyltransferase (EC 2.5.1.-) Gene SCO4494, often clustered with other genes in menaquinone via futalosine pathway Menaquinone via futalosine step 1 Menaquinone via futalosine step 2 Menaquinone via futalosine step 3 Menaquinone via futalosine step 4 Menaquinone via futalosine step 4, possible alternative Ubiquinone/menaquinone biosynthesis methyltransferase UbiE (EC 2.1.1.-) Menaquinone_and_Phylloquinone_Biosynthesis 1,4-dihydroxy-2-naphthoate octaprenyltransferase (EC 2.5.1.74) 2-heptaprenyl-1,4-naphthoquinone methyltransferase (EC 2.1.1.-) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (EC 2.2.1.9) 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) Menaquinone-specific isochorismate synthase (EC 5.4.4.2) Naphthoate synthase (EC 4.1.3.36) O-succinylbenzoate-CoA synthase (EC 4.2.1.-) O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26) Ubiquinone/menaquinone biosynthesis methyltransferase UbiE (EC 2.1.1.-) Plastoquinone_Biosynthesis 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) Gamma-tocopherol C-methyltransferase (EC 2.1.1.95) Homogentisate prenyltransferase Tocopherol cyclase (EC 5.-.-.-) Pyrroloquinoline_Quinone_biosynthesis Coenzyme PQQ synthesis protein A Coenzyme PQQ synthesis protein B Coenzyme PQQ synthesis protein C Coenzyme PQQ synthesis protein D Coenzyme PQQ synthesis protein E Coenzyme PQQ synthesis protein F (EC 3.4.99.-) Microsomal dipeptidase (EC 3.4.13.19) Tocopherol_Biosynthesis 2-methyl-6-phytyl-1,4-benzoquinone cyclase 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) Gamma-tocopherol C-methyltransferase (EC 2.1.1.95) Homogentisate prenyltransferase Ubiquinone_Biosynthesis 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (EC 1.14.13.-) 2-octaprenyl-6-methoxyphenol hydroxylase (EC 1.14.13.-) 3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64) 3-polyprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) 4-hydroxybenzoate polyprenyltransferase (EC 2.5.1.-) Chorismate--pyruvate lyase (EC 4.1.3.40) NAD(P)H-flavin reductase (EC 1.5.1.29) (EC 1.16.1.3) Protein YigP (COG3165) clustered with ubiquinone biosynthetic genes Ubiquinone biosynthesis enzyme COQ7 Ubiquinone biosynthesis monooxygenase UbiB Ubiquinone/menaquinone biosynthesis methyltransferase UbiE (EC 2.1.1.-) 02 Riboflavin, FMN, FAD Flavodoxin Flavodoxin Flavodoxin 1 Flavodoxin 2 Flavoprotein MioC Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) NAD(P)H oxidoreductase YRKL (EC 1.6.99.-) Riboflavin,_FMN_and_FAD_metabolism 3,4-dihydroxy-2-butanone 4-phosphate synthase 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9) CTP-dependent archaeal riboflavin kinase DNA-binding HTH domain in riboflavin kinase Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) FMN adenylyltransferase (EC 2.7.7.2) FO biosynthesis ArfB GTP cyclohydrolase II (EC 3.5.4.25) GTP cyclohydrolase III (EC 3.5.4.29) Lumazine protein, riboflavin synthase homolog Pyrimidine deaminase archaeal predicted (EC 3.5.4.26) Pyrimidine deaminase eukaryotic (EC 3.5.4.26) Riboflavin kinase (EC 2.7.1.26) Riboflavin synthase alpha chain (EC 2.5.1.9) Riboflavin synthase archaeal (EC 2.5.1.9) Riboflavin transporter PnuX Substrate-specific component RibU of riboflavin ECF transporter riboflavin_to_FAD 3,4-dihydroxy-2-butanone 4-phosphate synthase CTP-dependent archaeal riboflavin kinase FMN adenylyltransferase (EC 2.7.7.2) Riboflavin kinase (EC 2.7.1.26) Riboflavin synthase alpha chain (EC 2.5.1.9) Riboflavin synthase archaeal (EC 2.5.1.9) 02 Tetrapyrroles Bilin_Biosynthesis 15,16-dihydrobiliverdin:ferredoxin oxidoreductase PebA (EC 1.3.7.2) Bilin biosynthesis protein CpeY Bilin biosynthesis protein CpeZ Bilin biosynthesis protein MpeU Bilin biosynthesis protein PecE Bilin biosynthesis protein PecF Biliverdin reductase (EC 1.3.1.24) Heme oxygenase (EC 1.14.99.3) Phycocyanobilin lyase alpha subunit Phycocyanobilin lyase beta subunit Phycocyanobilin:ferredoxin oxidoreductase PcyA (EC 1.3.7.5) Phycoerythrobilin:ferredoxin oxidoreductase PebB (EC 1.3.7.3) Chlorophyll_Biosynthesis 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase BchC 2-vinyl bacteriochlorophyllide hydratase BchF (EC 4.2.1.-) Bacteriochlorophyllide c C12 methyltransefase BchR Bacteriochlorophyllide c C8 methyltransefase BchQ Chlorophyll a synthase ChlG (EC 2.5.1.62) Chlorophyll a, chlorophyllide a oxygenase (EC 1.14.13.-) Chlorophyllide reductase subunit BchX (EC 1.18.-.-) Chlorophyllide reductase subunit BchY (EC 1.18.-.-) Chlorophyllide reductase subunit BchZ (EC 1.18.-.-) Divinyl protochlorophyllide a 8-vinyl-reductase (EC 1.3.1.75) Geranylgeranyl hydrogenase BchP Light-dependent protochlorophyllide reductase (EC 1.3.1.33) Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein ChlL (EC 1.18.-.-) Light-independent protochlorophyllide reductase subunit B (EC 1.18.-.-) Light-independent protochlorophyllide reductase subunit N (EC 1.18.-.-) Mg protoporphyrin IX monomethyl ester oxidative cyclase (aerobic) (EC 1.14.13.81) Mg-protoporphyrin IX monomethyl ester oxidative cyclase (anaerobic) (EC 1.14.13.81) Mg-protoporphyrin O-methyltransferase (EC 2.1.1.11) Protein BchJ, involved in reduction of C-8 vinyl of divinyl protochlorophyllide Protoporphyrin IX Mg-chelatase subunit D (EC 6.6.1.1) Protoporphyrin IX Mg-chelatase subunit H (EC 6.6.1.1) Protoporphyrin IX Mg-chelatase subunit I (EC 6.6.1.1) Putative chaperon-like protein Ycf39 for quinone binding in Photosystem II Chlorophyll_Degradation Pheophorbide a oxygenase (EC 1.14.-.-) Red chlorophyll catabolite reductase (EC 1.-.-.-) Cobalamin_synthesis Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Adenosylcobinamide-phosphate synthase Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Cobalamin biosynthesis protein BluB Cobalamin biosynthesis protein CbiG Cobalamin synthase Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Cobalt-precorrin-3b C17-methyltransferase Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Cobalt-precorrin-6 synthase, anaerobic Cobalt-precorrin-6x reductase (EC 1.3.1.54) Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Cobyric acid synthase Cobyrinic acid A,C-diamide synthase L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Threonine kinase in B12 biosynthesis Coenzyme_B12_biosynthesis 5,6-dimethylbenzimidazole synthase, flavin destructase family ATPase component CbiO of energizing module of cobalt ECF transporter Additional lipoprotein component of predicted cobalamin ECF transporter Additional substrate-specific component CbiN of cobalt ECF transporter Adenosylcobinamide amidohydrolase (EC 3.5.1.90) Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Adenosylcobinamide-phosphate synthase Aerobic cobaltochelatase CobS subunit (EC 6.6.1.2) Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) CblX, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase CblY, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase ChlD component of cobalt chelatase involved in B12 biosynthesis ChlI component of cobalt chelatase involved in B12 biosynthesis Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) Cob(II)alamin reductase CobN component of cobalt chelatase involved in B12 biosynthesis CobW GTPase involved in cobalt insertion for B12 biosynthesis Cobalamin biosynthesis protein CbiG Cobalamin biosynthesis protein CobG Cobalamin synthase Cobalamine-related hypothetical metal-binding protein CrdX Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Cobalt-precorrin-3b C17-methyltransferase Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Cobalt-precorrin-6 synthase, anaerobic Cobalt-precorrin-6x reductase (EC 1.3.1.54) Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Cobyric acid synthase Cobyrinic acid A,C-diamide synthase Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter HoxN/HupN/NixA family cobalt transporter HupE-UreJ family cobalt transporter L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Optional hypothetical component of the B12 transporter BtuM Optional hypothetical component of the B12 transporter BtuN Outer membrane vitamin B12 receptor BtuB Precorrin-6A synthase (EC 2.1.1.152) Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis Predicted cobalt ABC transporter periplasmic component Predicted cobalt transporter CbtA Predicted cobalt transporter CbtC Predicted cobalt transporter in Bacteroides_Porphyromonas Predicted cobalt transporter in Mycobacteria Predicted cobalt transporter in Thermoplasma Predicted cobalt transporter in sulfate-reducing delta-proteobacteria Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Substrate-specific component CbiM of cobalt ECF transporter Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole Substrate-specific component CbrT of predicted cobalamin ECF transporter Threonine kinase in B12 biosynthesis Transmembrane component CbiQ of energizing module of cobalt ECF transporter Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Vitamin B12 ABC transporter, ATPase component BtuD Vitamin B12 ABC transporter, B12-binding component BtuF Vitamin B12 ABC transporter, permease component BtuC Heme_and_Siroheme_Biosynthesis 5-aminolevulinate synthase (EC 2.3.1.37) Coproporphyrinogen III oxidase, aerobic (EC 1.3.3.3) Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22), divergent, putative Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22), divergent, putative 2 Distant homolog of E. coli HemX protein in Xanthomonadaceae Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) Glutamyl-tRNA reductase (EC 1.2.1.70) Glutamyl-tRNA synthetase (EC 6.1.1.17) HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria Hypothetical membrane protein, possible involvement in cytochrome functioning/assembly Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent Porphobilinogen deaminase (EC 2.5.1.61) Porphobilinogen synthase (EC 4.2.1.24) Precorrin-2 oxidase (EC 1.3.1.76) Protoporphyrinogen IX oxidase, aerobic (EC 1.3.3.4) Protoporphyrinogen IX oxidase, oxygen-independent, HemG (EC 1.3.-.-) Putative coproporphyrinogen III oxidase of BS HemN-type, oxygen-independent (EC 1.3.99.22), in heat shock gene cluster Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake Sirohydrochlorin ferrochelatase (EC 4.99.1.4) Uroporphyrinogen III decarboxylase (EC 4.1.1.37) Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Uroporphyrinogen-III synthase (EC 4.2.1.75) Uroporphyrinogen-III synthase, divergent, Flavobacterial type (EC 4.2.1.75) Uroporphyrinogen-III synthase, divergent, Francisella type (EC 4.2.1.75) Heme_biosynthesis_orphans Cytochrome cd1 nitrite reductase (EC:1.7.2.1) Heme biosynthesis protein related to NirD Heme biosynthesis protein related to NirD and NirG Heme biosynthesis protein related to NirG Heme biosynthesis protein related to NirH Heme biosynthesis protein related to NirL Heme biosynthesis protein related to NirL and NirH Heme d1 biosynthesis protein NirD Heme d1 biosynthesis protein NirG Heme d1 biosynthesis protein NirH Heme d1 biosynthesis protein NirJ Heme d1 biosynthesis protein NirL Radical SAM domain heme biosynthesis protein 02 Molybdopterin_cytosine_dinucleotide CTP:molybdopterin cytidylyltransferase Hypothetical protein YagQ Molybdopterin biosynthesis enzyme Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit YagS Periplasmic aromatic aldehyde oxidoreductase, iron-sulfur subunit YagT Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR Thiamin_biosynthesis 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) 5-FCL-like protein ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Additional substrate-binding component of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Cysteine desulfurase (EC 2.8.1.7), IscS subfamily Glycine oxidase ThiO (EC 1.4.3.19) Hydroxyethylthiazole kinase (EC 2.7.1.50) Hydroxymethylpyrimidine ABC transporter, ATPase component Hydroxymethylpyrimidine ABC transporter, substrate-binding component Hydroxymethylpyrimidine ABC transporter, transmembrane component Hydroxymethylpyrimidine synthesis protein THI5 Phosphomethylpyrimidine kinase (EC 2.7.4.7) Predicted hydroxymethylpyrimidine transporter CytX Predicted thiamin transporter PnuT Predicted thiamin transporter ThiT Predicted thiazole transporter ThiU Putative cysteine desulfurase, associated with tRNA 4-thiouridine synthase Rhodanese-like domain required for thiamine synthesis Substrate-specific component ThiT of thiamin ECF transporter Substrate-specific component ThiW of predicted thiazole ECF transporter Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Sulfur carrier protein ThiS Sulfur carrier protein adenylyltransferase ThiF Thiamin ABC transporter, ATPase component Thiamin ABC transporter, substrate-binding component Thiamin ABC transporter, transmembrane component Thiamin biosynthesis protein ThiC Thiamin pyrophosphokinase (EC 2.7.6.2) Thiamin transport gene THI10 Thiamin-phosphate phosphatase (EC 3.1.3.-) Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Thiamin-phosphate synthase ThiN (EC 2.5.1.3) Thiamin-regulated hypothetical deacetylase Thiamin-regulated outer membrane receptor Omr1 Thiaminase II (EC 3.5.99.2) Thiamine kinase (EC 2.7.1.89) Thiamine-monophosphate kinase (EC 2.7.4.16) Thiazole biosynthesis protein ThiG Thiazole biosynthesis protein ThiH Thiazole biosynthetic enzyme Thi4 Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine YjbQ (alternate ThiE) tRNA S(4)U 4-thiouridine synthase (former ThiI) 01 DNA Metabolism 02 CRISPs CRISPRs CRISPR-associated RecB family exonuclease Cas4a CRISPR-associated RecB family exonuclease Cas4b CRISPR-associated helicase Cas3 CRISPR-associated helicase Cas3, protein CRISPR-associated negative autoregulator CRISPR-associated protein Cas1 CRISPR-associated protein Cas2 CRISPR-associated protein Cas7 CRISPR-associated protein MTH1087 CRISPR-associated protein, CT1133 family CRISPR-associated protein, CT1134 family CRISPR-associated protein, CT1972 family CRISPR-associated protein, CT1973 family CRISPR-associated protein, CT1974 CRISPR-associated protein, CT1975 family CRISPR-associated protein, CT1976 CRISPR-associated protein, Csn1 family CRISPR-associated protein, MJ0381 family CRISPR-associated protein, SAG0894 family CRISPR-associated protein, TM1800 family CRISPR-associated protein, TM1801 family CRISPR-associated protein, TM1802 family CRISPR-associated protein, WS1616 family corresponds to STY3070 from Accession AL513382: Salmonella typhi CT18 CRISP_Cmr_Cluster CRISPR-associated RAMP Cmr1 CRISPR-associated RAMP Cmr2 CRISPR-associated RAMP Cmr3 CRISPR-associated RAMP Cmr4 CRISPR-associated RAMP Cmr5 CRISPR-associated RAMP Cmr6 CRISPR-associated protein Cas02710 CRISPR-associated protein Csx11 CRISPR-associated protein NE0113 CRISPR-associated protein TM1812 DUF324 domain containing Cmr2-like protein DUF324 domain containing Cmr6-like protein FIG054491: hypothetical protein 02 DNA recombination DNA_recombination,_archaeal DNA repair and recombination protein RadA DNA repair and recombination protein RadB RuvABC_plus_a_hypothetical Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) FIG000859: hypothetical protein Holliday junction DNA helicase RuvA Holliday junction DNA helicase RuvB 02 DNA repair 2-phosphoglycolate_salvage 2-deoxyglucose-6-phosphate hydrolase YniC Phosphoglycolate phosphatase (EC 3.1.3.18) Putative phosphatase YfbT Putative phosphatase YieH Putative phosphatase YqaB Similar to phosphoglycolate phosphatase, clustered with ribosomal large subunit pseudouridine synthase C Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase ATP-dependent_Nuclease ATP-dependent nuclease, subunit A ATP-dependent nuclease, subunit B DNA_Repair_Base_Excision ATP-dependent DNA ligase (EC 6.5.1.1) ATP-dependent DNA ligase (EC 6.5.1.1) LigC ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD DNA ligase (EC 6.5.1.2) DNA polymerase I (EC 2.7.7.7) DNA polymerase II (EC 2.7.7.7) DNA-3-methyladenine glycosylase (EC 3.2.2.20) DNA-3-methyladenine glycosylase II (EC 3.2.2.21) Endonuclease III (EC 4.2.99.18) Endonuclease VIII Exodeoxyribonuclease I (EC 3.1.11.1) Flap structure-specific endonuclease (EC 3.-.-.-) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) Ku domain protein Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) Single-stranded-DNA-specific exonuclease RecJ, clostridial paralog Single-stranded-DNA-specific exonuclease RecJ, cyanobacterial paralog Uracil-DNA glycosylase, family 1 DNA_repair,_UvrABC_system Excinuclease ABC subunit A Excinuclease ABC subunit A paralog in greater Bacteroides group Excinuclease ABC subunit A paralog of unknown function Excinuclease ABC subunit A, dimeric form Excinuclease ABC subunit B Excinuclease ABC subunit C Excinuclease cho (excinuclease ABC alternative C subunit) DNA_repair,_bacterial A/G-specific adenine glycosylase (EC 3.2.2.-) ADA regulatory protein Alkylated DNA repair protein AlkB DNA mismatch repair endonuclease MutH DNA polymerase IV (EC 2.7.7.7) DNA polymerase-like protein MT3142 DNA polymerase-like protein PA0670 DNA recombination protein RmuC DNA recombination-dependent growth factor C DNA repair exonuclease family protein YhaO DNA repair protein RadA DNA repair protein RadC DNA repair protein RecN DNA-damage-inducible protein I DNA-damage-inducible protein J Endonuclease IV (EC 3.1.21.2) Endonuclease V (EC 3.1.21.7) Exodeoxyribonuclease III (EC 3.1.11.2) Exodeoxyribonuclease VII large subunit (EC 3.1.11.6) Exodeoxyribonuclease VII small subunit (EC 3.1.11.6) Exonuclease SbcC Exonuclease SbcD G:T/U mismatch-specific uracil/thymine DNA-glycosylase Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) RecA protein Recombinational DNA repair protein RecT (prophage associated) SOS-response repressor and protease LexA (EC 3.4.21.88) Single-stranded DNA-binding protein Very-short-patch mismatch repair endonuclease (G-T specific) DNA_repair,_bacterial_DinG_and_relatives ATP-dependent helicase DinG/Rad3 DinG family ATP-dependent helicase CPE1197 DinG family ATP-dependent helicase YoaA DinG family ATP-dependent helicase YpvA DNA_repair,_bacterial_MutL-MutS_system Clostridial MutS2-related protein DNA mismatch repair protein MutL DNA mismatch repair protein MutS MutS domain protein, family 2 MutS domain protein, family 4 MutS domain protein, family 5 MutS domain protein, family 6 MutS-related protein, family 1 Recombination inhibitory protein MutS2 DNA_repair,_bacterial_RecBCD_pathway ATP-dependent DNA helicase SCO5183 ATP-dependent DNA helicase SCO5184 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) Exodeoxyribonuclease V beta chain (EC 3.1.11.5) Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) Protease III precursor (EC 3.4.24.55) RecD-like DNA helicase Atu2026 RecD-like DNA helicase YrrC DNA_repair,_bacterial_RecFOR_pathway ATP-dependent DNA helicase RecQ ATP-dependent DNA helicase, RecQ family DNA recombination and repair protein RecF DNA recombination and repair protein RecO RecA protein Recombination protein RecR Single-stranded DNA-binding protein Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) Single-stranded-DNA-specific exonuclease RecJ, Bacteriophage SPBc2-type Single-stranded-DNA-specific exonuclease RecJ, clostridial paralog Single-stranded-DNA-specific exonuclease RecJ, cyanobacterial paralog DNA_repair,_bacterial_UmuCD_system Error-prone repair protein UmuD Error-prone, lesion bypass DNA polymerase V (UmuC) RecA protein SOS-response repressor and protease LexA (EC 3.4.21.88) DNA_repair,_bacterial_UvrD_and_related_helicases ATP-dependent DNA helicase Rep ATP-dependent DNA helicase UvrD/PcrA ATP-dependent DNA helicase UvrD/PcrA, actinomycete paralog ATP-dependent DNA helicase UvrD/PcrA, clostridial paralog ATP-dependent DNA helicase UvrD/PcrA, clostridial paralog 2 ATP-dependent DNA helicase UvrD/PcrA, proteobacterial paralog ATP-dependent DNA helicase UvrD/PcrA/Rep ATP-dependent DNA helicase UvrD/PcrA/Rep family, Francisella type ATP-dependent DNA helicase UvrD/PcrA/Rep, cyanobacterial paralog ATP-dependent DNA helicase UvrD/PcrA/Rep, epsilon proteobacterial type 1 ATP-dependent DNA helicase UvrD/PcrA/Rep, epsilon proteobacterial type 2 ATP-dependent DNA helicase pcrA (EC 3.6.1.-) Conjugative transposon transfer DNA helicase DNA helicase IV Plasmid conjugative transfer DNA helicase TrhI putative ATP-dependent DNA helicase YjcD DNA_repair,_bacterial_photolyase Cryptochrome Deoxyribodipyrimidine photolyase (EC 4.1.99.3) Deoxyribodipyrimidine photolyase, single-strand-specific Deoxyribodipyrimidine photolyase, type II (EC 4.1.99.3) DNA_repair_and_recombination_eukaryotic DNA repair protein RAD51 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein RAD57 Meiotic recombination protein DMC1 Nonhomologous_End-Joining_in_Bacteria ATP-dependent DNA ligase (EC 6.5.1.1) LigC ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD Ku domain protein Uracil-DNA_glycosylase Domain often clustered or fused with uracil-DNA glycosylase G:T/U mismatch-specific uracil/thymine DNA-glycosylase U/G & T/G mismatch specific glycosylase (Pa-MIG) Uracil DNA glycosylase superfamily protein Uracil-DNA glycosylase family protein, clostridial type Uracil-DNA glycosylase, family 1 Uracil-DNA glycosylase, family 3 Uracil-DNA glycosylase, family 4 Uracil-DNA glycosylase, family 5 Uracil-DNA glycosylase, putative family 6 02 DNA replication DNA-replication ATP-dependent DNA helicase RecG (EC 3.6.1.-) ATP-dependent DNA helicase RecQ Arrested fork binding Chromosomal replication initiator protein DnaA Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) DNA polymerase I (EC 2.7.7.7) DNA polymerase II (EC 2.7.7.7) DNA polymerase III alpha subunit (EC 2.7.7.7) DNA polymerase III beta subunit (EC 2.7.7.7) DNA polymerase III chi subunit (EC 2.7.7.7) DNA polymerase III delta prime subunit (EC 2.7.7.7) DNA polymerase III delta subunit (EC 2.7.7.7) DNA polymerase III epsilon subunit (EC 2.7.7.7) DNA polymerase III psi subunit (EC 2.7.7.7) DNA polymerase III subunits gamma and tau (EC 2.7.7.7) DNA polymerase III theta subunit (EC 2.7.7.7) DNA primase (EC 2.7.7.-) DNA primase (EC 2.7.7.-), phage-associated DNA primase TraC (EC 2.7.7.-) DNA repair protein RecN DNA replication protein DnaC DNA replication terminus site-binding protein Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) Exodeoxyribonuclease V beta chain (EC 3.1.11.5) Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) Helicase PriA essential for oriC/DnaA-independent DNA replication Helicase loader DnaI Holliday junction DNA helicase RuvA Holliday junction DNA helicase RuvB Primosomal protein I Primosomal replication protein N Primosomal replication protein N prime prime RecA protein Recombination protein RecR Replicative DNA helicase (EC 3.6.1.-) Replicative DNA helicase (EC 3.6.1.-) [SA14-24] Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) Transcription-repair coupling factor DNA_Helicase_of_Unknown_Function DNA helicase (Rad25 homolog) Hypothetical protein (associated with DNA helicase - Rad25 homolog) DNA_replication,_archaeal ATP-dependent DNA ligase (EC 6.5.1.1) Archaeal DNA polymerase I (EC 2.7.7.7) Archaeal DNA polymerase II large subunit (EC 2.7.7.7) Archaeal DNA polymerase II small subunit (EC 2.7.7.7) Cell division control protein 6 DNA polymerase sliding clamp protein PCNA DNA primase large subunit (EC 2.7.7.-) DNA primase small subunit (EC 2.7.7.-) DNA replication helicase protein MCM Flap structure-specific endonuclease (EC 3.-.-.-) Origin of replication recognition protein Replication factor A (ssDNA-binding protein) Replication factor C large subunit Replication factor C small subunit Ribonuclease HII (EC 3.1.26.4) DNA_topoisomerases,_Type_I,_ATP-independent DNA topoisomerase I (EC 5.99.1.2) DNA topoisomerase I, eukaryotic-type (EC 5.99.1.2) DNA topoisomerase IB (poxvirus type) (EC 5.99.1.2) DNA topoisomerase III (EC 5.99.1.2) DNA topoisomerase III domain DNA topoisomerase III, Bacillus plasimid type (EC 5.99.1.2) DNA topoisomerase III, Bacteroidales-type (EC 5.99.1.2) DNA topoisomerase III, Burkholderia type (EC 5.99.1.2) DNA topoisomerase III, TraE-type (EC 5.99.1.2) DNA topoisomerase V Plasmid associated TOPRIM domain protein Similar to C-terminal Zn-finger domain of DNA topoisomerase I DNA_topoisomerases,_Type_II,_ATP-dependent DNA gyrase subunit A (EC 5.99.1.3) DNA gyrase subunit B (EC 5.99.1.3) DNA reverse gyrase (EC 5.99.1.-) DNA topoisomerase II (EC 5.99.1.3) DNA topoisomerase VI subunit A (EC 5.99.1.3) DNA topoisomerase VI subunit B (EC 5.99.1.3) Topoisomerase IV subunit A (EC 5.99.1.-) Topoisomerase IV subunit B (EC 5.99.1.-) Plasmid_replication Chromosome (plasmid) partitioning protein ParA Chromosome (plasmid) partitioning protein ParB Plasmid replication protein RepA Plasmid replication protein RepB Plasmid replication protein RepC 02 DNA uptake, competence Competence_in_Streptococci Competence positive regulator ComW Competence-specific sigma factor ComX Competence-stimulating peptide (CSP) precursor ComC Competence-stimulating peptide ABC transporter ATP-binding protein ComA Competence-stimulating peptide ABC transporter permease protein ComB Histidine kinase of the competence regulon ComD Response regulator of the competence regulon ComE Transcriptional regulator SpxA1 Transcriptional regulator SpxA2 DNA_processing_cluster DNA polymerase III subunits gamma and tau (EC 2.7.7.7) DNA topoisomerase III (EC 5.99.1.2) FIG000557: hypothetical protein co-occurring with RecR FIG015094: hypothetical protein Inhibitor of pro-sigmaK processing BofA Protein involved in catabolism of external DNA Recombination protein RecR Gram_Positive_Competence ComF operon protein A, DNA transporter ATPase ComF operon protein C Competence protein CoiA DNA-entry nuclease (Competence-specific nuclease) (EC 3.1.30.-) Late competence protein ComC, processing protease Late competence protein ComEA, DNA receptor Late competence protein ComEC, DNA transport Late competence protein ComGA, access of DNA to ComEA Late competence protein ComGB, access of DNA to ComEA Negative regulator of genetic competence MecA Natural_DNA_Transformation_in_Vibrio Extracellular deoxyribonuclease Dns (EC 3.1.21.-) Extracellular deoxyribonuclease Xds Positive regulator of competence TfoX 02 DNA_phosphorothioation 3'-phosphoadenosine 5'-phosphosulfate sulfurtransferase DndC DNA sulfur modification protein DndB DNA sulfur modification protein DndD DNA sulfur modification protein DndE NifS-like cysteine desulfurase DndA DNA_structural_proteins,_bacterial Chromosome partition protein MukB Chromosome partition protein MukE Chromosome partition protein MukF DNA-binding protein Fis DNA-binding protein HBsu DNA-binding protein HU DNA-binding protein HU-alpha DNA-binding protein HU-beta Integration host factor alpha subunit Integration host factor beta subunit Nucleoid-associated_proteins_in_Bacteria Cnu protein DNA-binding protein H-NS DNA-binding protein stpA Haemolysin expression modulating protein Haemolysin expression modulating protein paralog Restriction-Modification_System Putative DNA-binding protein in cluster with Type I restriction-modification system Putative predicted metal-dependent hydrolase Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) Type III restriction-modification system DNA endonuclease res (EC 3.1.21.5) Type III restriction-modification system StyLTI enzyme res (EC 3.1.21.5) Type III restriction-modification system methylation subunit (EC 2.1.1.72) Type_I_Restriction-Modification Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) YcfH Deoxyribonuclease TatD Putative deoxyribonuclease YcfH Putative deoxyribonuclease YjjV Putative deoxyribonuclease similar to YcfH, type 2 Putative deoxyribonuclease similar to YcfH, type 3 Putative deoxyribonuclease similar to YcfH, type 4 Putative deoxyribonuclease similar to YcfH, type 5 01 Dormancy and Sporulation 02 Spore DNA protection Dipicolinate_Synthesis Dipicolinate synthase subunit A (EC 4.2.1.52) Dipicolinate synthase subunit B Small_acid-soluble_spore_proteins Endopeptidase spore protease Gpr (EC 3.4.24.78) Small acid-soluble spore protein, alpha-type SASP Small acid-soluble spore protein, alpha/beta family, SASP_1 Small acid-soluble spore protein, alpha/beta family, SASP_2 Small acid-soluble spore protein, alpha/beta family, SASP_3 Small acid-soluble spore protein, alpha/beta family, SASP_4 Small acid-soluble spore protein, alpha/beta family, SASP_5 Small acid-soluble spore protein, alpha/beta family, SASP_6 Small acid-soluble spore protein, beta-type SASP Small acid-soluble spore protein, gamma-type SASP 02 Bacillus_Sporulation_Killing_Factor_A_Biosynthetic_Cluster ABC transporter ATP-binding protein SkfF ABC transporter SkfE Amino terminal CAAX family protease SkfD Antimicrobial protein SkfB Antimicrobial protein SkfC Protein SkfG Protein SkfH Sporulation killing factor A SkfA Bacillus_biofilm_matrix_protein_component_TasA_and_homologs Cell envelope-bound metalloprotease, Camelysin (EC 3.4.24.-) Hypothetical protein in cluster with SinR and SinI Immune inhibitor A metalloprotease PlcR activating protein PapR, quorum-sensing effector Secreted and spore coat-associated protein 1, similar to biofilm matrix component TasA and to camelysin Secreted and spore coat-associated protein 2, similar to biofilm matrix component TasA and to camelysin Secreted and spore coat-associated protein 3, similar to biofilm matrix component TasA and to camelysin Signal peptidase SipW (EC 3.4.21.89), required for TasA secretion SinI protein, antagonist of SinR SinR, regulator of post-exponential-phase responses genes (competence and sporulation) Slr, positive regulator of the extracellular matrix biosynthesis operon yqxM-sipW-tasA Sporulation-associated protease N-terminal domain protein Stationary phase secreted protein TasA, major protein component of biofilm matrix Subtilase family domain protein Transcriptional activator PlcR YqxM protein, required for localization of TasA to extracellular matrix Exosporium Alanine racemase (EC 5.1.1.1) in exosporium BclA protein Exosporium SOD Exosporium protein A Exosporium protein B @ Spore coat protein G Exosporium protein C Exosporium protein D Exosporium protein D-like protein Exosporium protein E Exosporium protein F Exosporium protein G Exosporium protein J Exosporium protein K Exosporium protein Y Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) in exosporium Outer spore coat protein E Persister_Cells Cell division inhibitor HipA protein HipB protein Ribosome modulation factor SpoVS_protein_family SpoVS-related protein, type 1 SpoVS-related protein, type 2 SpoVS-related protein, type 3 SpoVS-related protein, type 4 SpoVS-related protein, type 5 Stage III sporulation protein AE Stage V sporulation protein required for dehydratation of the spore core and assembly of the coat (SpoVS) Spore_Core_Dehydration Fused spore maturation proteins A and B Penicillin-binding protein DacC Spore maturation protein A Spore maturation protein A-like protein Spore maturation protein B Spore_germination Germination-specific N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28), cell wall hydrolase CwlD Protein GerPA, required for proper assembly of spore coat, mutations lead to super-dormant spore Protein GerPB, required for proper assembly of spore coat, mutations lead to super-dormant spore Protein GerPC, required for proper assembly of spore coat, mutations lead to super-dormant spore Protein GerPD, required for proper assembly of spore coat, mutations lead to super-dormant spore Protein GerPE, required for proper assembly of spore coat, mutations lead to super-dormant spore Protein GerPF, required for proper assembly of spore coat, mutations lead to super-dormant spore Putative peptidoglycan hydrolase YvbX, NOT involved in spore germination Putative spore germination protein, GerB family Similar to proteins GerPF and GerPA Spo0E-like putative sporulation regulatory protein in grePA-PF operon Spore cortex-lytic enzyme CwlJ Spore cortex-lytic enzyme, N-acetylglucosaminidase SleL (EC 3.2.1.-) Spore cortex-lytic enzyme, lytic transglycosylase SleB Spore germination protein GerAA, germination response to L-alanine and related amino acids (earliest stage) Spore germination protein GerAB, germination response to L-alanine and related amino acids (earliest stage) Spore germination protein GerAC, germination response to L-alanine and related amino acids (earliest stage) Spore germination protein GerBA, germination response to combination of glucose, fructose, L-asparagine, and K+ (earliest stage) Spore germination protein GerBB, germination response to combination of glucose, fructose, L-asparagine, and K+ (earliest stage) Spore germination protein GerBC, germination response to combination of glucose, fructose, L-asparagine, and K+ (earliest stage) Spore germination protein GerD Spore germination protein GerHA/GerIA Spore germination protein GerHB/GerIB Spore germination protein GerHC/GerIC Spore germination protein GerKA Spore germination protein GerKB Spore germination protein GerKC Spore germination protein GerLA Spore germination protein GerLB Spore germination protein GerLC Spore germination protein GerN (inosine-dependent germination), Na+/H+ antiporter Spore germination protein GerQA Spore germination protein GerQB Spore germination protein GerQC Spore germination protein GerSA Spore germination protein GerSB Spore germination protein GerSC Spore germination protein GerXA (on pXO1) Spore germination protein GerXB (on pXO1) Spore germination protein GerXC (on pXO1) Spore germination protein GerYA Spore germination protein GerYB Spore germination protein GerYC Spore germination protein YpeB Spore protein YdhD, not involved in spore germination Uncharacterized protein YkvT, NOT involved in spore germination Uncharacterized spore germination protein YndD Uncharacterized spore germination protein YndE Uncharacterized spore germination protein YndF Spore_pigment_biosynthetic_cluster_in_Actinomycetes Acyl carrier protein WhiE V Aromatase WhiE VI Polyketide beta-ketoacyl synthase WhiE-KS Polyketide beta-ketoacyl synthase WhiE-KS paralog Polyketide chain length factor WhiE-CLF Polyketide chain length factor WhiE-CLF paralog Polyketide cyclase WhiE II Polyketide cyclase WhiE VII Polyketide hydroxylase WhiE VIII WhiE I protein of unknown function Sporulation-associated_proteins_with_broader_functions Peptidyl-tRNA hydrolase (EC 3.1.1.29) Protein of unknown function identified by role in sporulation (SpoVG) RNA polymerase sporulation specific sigma factor SigH Stage III sporulation protein AE Sporulation_Cluster_III_A Stage III sporulation protein AA Stage III sporulation protein AB Stage III sporulation protein AC Stage III sporulation protein AD Stage III sporulation protein AE Stage III sporulation protein AF Stage III sporulation protein AG Stage III sporulation protein AH Sporulation_draft KinB signaling pathway activation protein Spo0E regulatory protein, specific dephosphorylation of Spo0A-P (stage 0 sporulation) Spore cortex-lytic enzyme precursor Spore germination protein GerD Sporulation kinase A (EC 2.7.13.3) Sporulation kinase B (EC 2.7.13.3) Sporulation kinase B homolog 1 Sporulation kinase B homolog 2 Sporulation thiol-disulfide oxidoreductase StoA precursor (Stage IV sporulation protein H) Stage 0 sporulation protein YaaT Stage 0 sporulation two-component response regulator (Spo0A) Stage V sporulation protein B spore peptidoglycan hydrolase (N-acetylglucosaminidase) (EC 3.2.1.-) Sporulation_gene_orphans KapB, lipoprotein required for KinB pathway to sporulation KapD, inhibitor of KinA pathway to sporulation RNA polymerase sporulation specific sigma factor SigE RNA polymerase sporulation specific sigma factor SigF RNA polymerase sporulation specific sigma factor SigG RNA polymerase sporulation specific sigma factor SigK Sporulation initiation phosphotransferase (Spo0F) Sporulation initiation phosphotransferase B (Spo0B) Sporulation kinase A (EC 2.7.13.3) Sporulation kinase B (EC 2.7.13.3) Sporulation kinase C (EC 2.7.13.3) Sporulation sigma-E factor processing peptidase (SpoIIGA) Stage 0 sporulation two-component response regulator (Spo0A) Stage II sporulation protein B Stage II sporulation protein D (SpoIID) Stage II sporulation protein M (SpoIIM) Stage II sporulation protein P Stage II sporulation protein related to metaloproteases (SpoIIQ) Stage II sporulation protein required for processing of pro-sigma-E (SpoIIR) Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE) Stage III sporulation protein AA Stage III sporulation protein AB Stage III sporulation protein AC Stage III sporulation protein AD Stage III sporulation protein AE Stage III sporulation protein AF Stage III sporulation protein AG Stage III sporulation protein AH Stage III sporulation protein D Stage IV sporulation pro-sigma-K processing enzyme (SpoIVFB) Stage IV sporulation protein A Stage IV sporulation protein B Stage IV sporulation protein FA (SpoIVFA) Stage V sporulation protein AA (SpoVAA) Stage V sporulation protein AB (SpoVAB) Stage V sporulation protein AC (SpoVAC) Stage V sporulation protein AD (SpoVAD) Stage V sporulation protein AE (SpoVAE) Stage V sporulation protein AF (SpoVAF) Stage V sporulation protein B Stage V sporulation protein D (Sporulation-specific penicillin-binding protein) Stage V sporulation protein E Stage V sporulation protein T, AbrB family transcriptional regulator (SpoVT) Stage V sporulation protein involved in spore cortex synthesis (SpoVR) Stage V sporulation protein required for dehydratation of the spore core and assembly of the coat (SpoVS) Stage V sporulation protein required for normal spore cortex and coat synthesis (SpoVM) Stage V sporulation protein whose disruption leads to the production of immature spores (SpoVK) Stage VI sporulation protein D 01 Fatty Acids, Lipids, and Isoprenoids 02 Fatty acids Acyl-CoA_thioesterase_II Acyl-CoA thioesterase II (EC 3.1.2.-) TesB-like acyl-CoA thioesterase 1 TesB-like acyl-CoA thioesterase 2 TesB-like acyl-CoA thioesterase 3 TesB-like acyl-CoA thioesterase 4 TesB-like acyl-CoA thioesterase 5 Carnitine_Metabolism_in_Microorganisms Carnitine operon protein CaiE Carnitine racemase (EC 5.-.-.-) Carnitinyl-CoA dehydratase (EC 4.2.1.-) Crotonobetaine carnitine-CoA ligase (EC 6.3.2.-) Crotonobetainyl-CoA dehydrogenase (EC 1.3.99.-) Crotonobetainyl-CoA:carnitine CoA-transferase (EC 2.8.3.-) Electron transfer flavoprotein, alpha subunit FixB Electron transfer flavoprotein, beta subunit FixA L-carnitine/gamma-butyrobetaine antiporter Transcriptional activatory protein CaiF Fatty_Acid_Biosynthesis_FASI 3-hydroxyacyl-coenzyme A dehydratase of elongase (EC 4.-.-.-) 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase of FASI (EC 4.2.1.61) 3-oxoacyl-[acyl-carrier-protein] reductase of FASI (EC 1.1.1.100) 3-oxoacyl-[acyl-carrier-protein] synthase of FASI (EC 2.3.1.41) 3-oxoacyl-coenzyme A reductase of elongase (EC 1.1.1.62) 4'-phosphopantetheinyl transferase of FASI (EC 2.7.8.7) Acetyl-coenzyme A carboxyl transferase of ACAC1 (EC 6.4.1.2) Acyl carrier protein of FASI Biotin carboxyl carrier protein of ACAC1 Biotin carboxylase of ACAC1 (EC 6.3.4.14) Enoyl-[acyl-carrier-protein] reductase of FASI (EC 1.3.1.9) Fatty acyl-coenzyme A elongase Fatty acyl-coenzyme A elongase 1 Fatty acyl-coenzyme A elongase 2 Fatty acyl-coenzyme A elongase 3 Oleoyl-[acyl carrier protein] thioesterase of FASI (EC 3.1.2.14) Trans-2,3-enoyl-cozyme A reductase of elongase (EC 1.-.-.-) [Acyl-carrier-protein] acetyl transferase of FASI (EC 2.3.1.38) [Acyl-carrier-protein] malonyl transferase of FASI (EC 2.3.1.39) [Acyl-carrier-protein] palmitoyl transferase of FASI (EC 2.3.1.-) Fatty_Acid_Biosynthesis_FASII (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase (EC 4.2.1.-) 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60) 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) 3-oxoacyl-[acyl-carrier-protein] synthase, KASI (EC 2.3.1.41) 3-oxoacyl-[acyl-carrier-protein] synthase, KASI, alternative (EC 2.3.1.41) 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41) 4'-phosphopantetheinyl transferase (EC 2.7.8.-) Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2) Acyl carrier protein Acyl carrier protein phosphodiesterase (EC 3.1.4.14) Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) Enoyl-[acyl-carrier-protein] reductase [FMN] (EC 1.3.1.9) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) Enoyl-[acyl-carrier-protein] reductase [NADPH] (EC 1.3.1.10) Holo-[acyl-carrier protein] synthase (EC 2.7.8.7) Holo-[acyl-carrier protein] synthase, alternative (EC 2.7.8.7) Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) Trans-2,cis-3-Decenoyl-ACP isomerase Transcriptional regulator of fatty acid biosynthesis FabT Fatty_acid_degradation_regulons 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Butyryl-CoA dehydrogenase (EC 1.3.99.2) Enoyl-CoA hydratase (EC 4.2.1.17) Fatty acid degradation regulator YsiA, TetR family Long-chain fatty acid transport protein Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Predicted transcriptional regulator for fatty acid degradation FadP, TetR family Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family Transcriptional regulator for fatty acid degradation FadR, GntR family Phospholipid_and_Fatty_acid_biosynthesis_related_cluster (3R)-hydroxymyristoyl-[ACP] dehydratase (EC 4.2.1.-) 3-hydroxydecanoyl-[ACP] dehydratase (EC 4.2.1.60) 3-oxoacyl-[ACP] reductase (EC 1.1.1.100) 3-oxoacyl-[ACP] synthase 3-oxoacyl-[ACP] synthase (EC 2.3.1.41) FabV like Acyl carrier protein (ACP1) Acyl carrier protein (ACP2) FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein FIG017861: hypothetical protein FIG018329: 1-acyl-sn-glycerol-3-phosphate acyltransferase FIG021862: membrane protein, exporter FIG022199: FAD-binding protein FIG025233: SAM-dependent methyltransferases FIG027190: Putative transmembrane protein FIG035331: hypothetical protein FIG064705: cation/hydrogen antiporter FIG085779: Lipoprotein FIG138576: 3-oxoacyl-[ACP] synthase (EC 2.3.1.41) FIG143263: Glycosyl transferase FIGfam138462: Acyl-CoA synthetase, AMP-(fatty) acid ligase Lysophospholipid acyltransferase Putative histidine ammonia-lyase protein Polyunsaturated_Fatty_Acids_synthesis 4'-phosphopantetheinyl transferase (EC 2.7.8.-), inferred for PFA pathway Enoyl-[acyl-carrier-protein] reductase [FMN] (EC 1.3.1.9), inferred for PFA pathway omega-3 polyunsaturated fatty acid synthase module PfaB/C omega-3 polyunsaturated fatty acid synthase subunit, PfaA omega-3 polyunsaturated fatty acid synthase subunit, PfaB omega-3 polyunsaturated fatty acid synthase subunit, PfaC putative transcriptional regulator, inferred for PFA pathway 02 Isoprenoids Acyclic_terpenes_utilization 3-hydroxy-3isohexenylglutaryl-CoA:acetate lyase Acyclic terpenes utilization regulator AtuR, TetR family Citronellol and citronellal dehydrogenase Citronellyl-CoA dehydrogenase Geranyl-CoA carboxylase biotin-containing subunit Geranyl-CoA carboxylase carboxyl transferase subunit Isohexenylglutaconyl-CoA hydratase Archaeal_lipids (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase (S)-3-O-geranylgeranylglyceryl phosphate synthase Acetyl-CoA acetyltransferase (EC 2.3.1.9) Digeranylgeranylglycerophospholipid reductase Dimethylallyltransferase (EC 2.5.1.1) Diphosphomevalonate decarboxylase (EC 4.1.1.33) Farnesylgeranyl pyrophosphate synthetase Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29) Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) Glycerol-1-phosphate dehydrogenase [NAD(P)] (EC 1.1.1.261) Hexaprenyl pyrophosphate synthetase Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34) Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) Isopentenyl phosphate kinase Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) Isopentenyl-diphosphate delta-isomerase, FMN-dependent (EC 5.3.3.2) Mevalonate kinase (EC 2.7.1.36) Phosphomevalonate kinase (EC 2.7.4.2) Putative Zn-dependent hydrolase in polyisoprenoid biosynthetic cluster Carotenoids "phi-Carotenoid synthase" (EC 1.3.-.- and EC 2.1.1-) 2-vinyl bacteriochlorophyllide hydratase BchF (EC 4.2.1.-) 4,4'-diapolycopene oxidase Beta-carotene hydroxylase Beta-carotene ketolase (EC 1.14.-.-) C50 carotenoid epsilon cyclase Carotenoid cis-trans isomerase (EC 5.2.-.-) CrtT-methyltransferase-like protein CrtV-methyltransferase-like protein Dehydrosqualene synthase (EC 2.5.1.-) Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29) Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) Hydroxyneurosporene dehydrogenase (EC 1.-.-.-) Hydroxyneurosporene methyltransferase (EC 2.1.1.-) Hydroxyneurosporene synthase Lycopene beta cyclase (EC 1.14.-.-) Lycopene cyclase Lycopene elongase (EC 2.5.1.-) Lycopene epsilon cyclase Methoxyneurosporene dehydrogenase (EC 1.14.99.-) Neurosporene desaturase (EC 1.-.-.-) Phytoene dehydrogenase (EC 1.14.99.-) Phytoene dehydrogenase and related proteins Phytoene desaturase (EC 1.14.99.-) Phytoene desaturase, neurosporene or lycopene producing (EC 1.3.-.-) Phytoene desaturase, pro-zeta-carotene producing (EC 1.-.-.-) Phytoene synthase (EC 2.5.1.32) Pro-zeta-carotene desaturase, prolycopene producing (EC 1.-.-.-) Regulator of carotenoid biosynthesis Squalene--hopene cyclase (EC 5.4.99.17) Zeaxanthin glucosyl transferase gamma-carotene desaturase, putative gamma-carotene hydroxylase Isoprenoid_Biosynthesis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Candidate gene for the hypothesized phosphomevalonate decarboxylase Dimethylallyltransferase (EC 2.5.1.1) Diphosphomevalonate decarboxylase (EC 4.1.1.33) Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34) Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) Isopentenyl phosphate kinase Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) Isopentenyl-diphosphate delta-isomerase, FMN-dependent (EC 5.3.3.2) Mevalonate kinase (EC 2.7.1.36) Phosphomevalonate kinase (EC 2.7.4.2) Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31) Myxoxanthophyll_biosynthesis_in_Cyanobacteria 2'-O-glycosyltransferase CruG Beta-carotene hydroxylase C-1'-hydroxylase CruF Lycopene cyclase, CruA type Polyprenyl_Diphosphate_Biosynthesis 4,4'-diaponeurosporenoate glycosyltransferase (EC 2.4.1.-) Dehydrosqualene desaturase (EC 1.14.99.-) (Diapophytoene desaturase) (4,4'-diapophytoene desaturase) Dehydrosqualene synthase (EC 2.5.1.-) Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29) Geranylgeranyl reductase (EC 1.3.1.83) Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) Glycosyl-4,4'-diaponeurosporenoate acyltransferase precursor (EC 2.3.1.-) Heptaprenyl diphosphate synthase component I (EC 2.5.1.30) Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) Octaprenyl-diphosphate synthase (EC 2.5.1.-) Solanesyl diphosphate synthase (EC 2.5.1.11) Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31) Terpen_biosynthesis UDP-glucoronosyl/UDP-glucosyl transferase family protein / contains similarity to glucosyltransferases; go_function: UDP-glycosyltransferase activity [goid 0008194]; go_function: transferase activity, transferring glycosyl groups [goid 0016757] cytochrome P450, putative / go_function: cytochrome P450 activity [goid 0015034]; go_function: oxygen binding [goid 0019825] terpene synthase/cyclase family protein / go_process: terpenoid biosynthesis [goid 0016114] polyprenyl_synthesis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2) Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) decaprenyl diphosphate synthase undecaprenyl diphosphate synthase 02 Phospholipids Glycerolipid_and_Glycerophospholipid_Metabolism_in_Bacteria 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Acyl carrier protein Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Alcohol dehydrogenase (EC 1.1.1.1) Aldehyde dehydrogenase (EC 1.2.1.3) Aldehyde dehydrogenase B (EC 1.2.1.22) Alpha-glycerophosphate oxidase (EC 1.1.3.21) Anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) Anaerobic glycerol-3-phosphate dehydrogenase subunit B (EC 1.1.5.3) CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) Cardiolipin synthetase (EC 2.7.8.-) Diacylglycerol kinase (EC 2.7.1.107) Dihydroxyacetone kinase family protein Glycerate kinase (EC 2.7.1.31) Glycerol kinase (EC 2.7.1.30) Glycerol-1-phosphate dehydrogenase [NAD(P)] (EC 1.1.1.261) Glycerol-3-phosphate acyltransferase (EC 2.3.1.15) Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) Phosphate:acyl-ACP acyltransferase PlsX Phosphatidate cytidylyltransferase (EC 2.7.7.41) Phosphatidylglycerophosphatase A (EC 3.1.3.27) Phosphatidylglycerophosphatase B (EC 3.1.3.27) Phosphatidylserine decarboxylase (EC 4.1.1.65) Sphingolipid_biosynthesis 3-dehydrosphinganine reductase (EC 1.1.1.102) 8-amino-7-oxononanoate synthase (EC 2.3.1.47) Acyl-CoA-dependent ceramide synthase (EC 2.3.1.24) Catalyzes the hydrolysis of ceramide to fatty acid and sphingosine (EC 3.5.1.23) Putative fatty acid desaturase (EC 1.14.-.-) Serine palmitoyltransferase (EC 2.3.1.50) 02 Triacylglycerols Triacylglycerol_metabolism Lysophospholipase (EC 3.1.1.5) Lysophospholipase L2 (EC 3.1.1.5) Monoglyceride lipase (EC 3.1.1.23) Phospholipase A1 precursor (EC 3.1.1.32, EC 3.1.1.4) Putative lipase in cluster with Phosphatidate cytidylyltransferase Triacylglycerol lipase (EC 3.1.1.3) Triacylglycerol lipase precursor (EC 3.1.1.3) 02 Cholesterol_catabolic_operon_in_Mycobacteria Acyl-CoA dehydrogenase IgrB Acyl-CoA dehydrogenase IgrC Conserved protein IgrD Enoyl coenzyme A hydratase IgrE Lipid carrier protein IgrF Putative cytochrome P450 IgrA Polyhydroxybutyrate_metabolism 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Acetoacetyl-CoA reductase (EC 1.1.1.36) Acetoacetyl-CoA synthetase (EC 6.2.1.16) Acetyl-CoA acetyltransferase (EC 2.3.1.9) Butyrate-acetoacetate CoA-transferase subunit A (EC 2.8.3.9) Butyrate-acetoacetate CoA-transferase subunit B (EC 2.8.3.9) D(-)-3-hydroxybutyrate oligomer hydrolase (EC 3.1.1.22) D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) D-beta-hydroxybutyrate permease Enoyl-CoA hydratase (EC 4.2.1.17) Intracellular PHB depolymerase (EC 3.1.1.-) Poly(3-hydroxyalkanoate) depolymerase Polyhydroxyalkanoate granule-associated protein PhaF Polyhydroxyalkanoic acid synthase Putative 3-hydroxyacyl-coa dehydrogenase Short chain fatty acids transporter polyhydroxyalkanoate granule-associated protein PhaI polyhydroxyalkanoate synthesis repressor PhaR 01 Iron acquisition and metabolism 02 Siderophores Alcaligin_Siderophore Iron-siderophore [Alcaligin] receptor Iron-sulfur protein in siderophore [Alcaligin] cluster Membrane efflux protein associated with [Alcaligin] siderophore cluster Putative iron reductase in siderophore [Alcaligin] cluster Siderophore [Alcaligin] biosynthesis complex, long chain Siderophore [Alcaligin] biosynthesis complex, short chain Siderophore [Alcaligin] biosynthetic enzyme (EC 1.14.13.59) Siderophore [Alcaligin] translocase AlcS Transcriptional regulator AlcR in siderophore [Alcaligin] cluster Bacillibactin_Siderophore 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) [bacillibactin] siderophore 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [bacillibactin] siderophore Bacillibactin synthetase component F (EC 2.7.7.-) Fe-bacillibactin uptake system FeuA, Fe-bacillibactin binding Fe-bacillibactin uptake system FeuA, regulatory component Fe-bacillibactin uptake system FeuB Fe-bacillibactin uptake system FeuC Fe-bacillibactin uptake system FeuD Isochorismatase (EC 3.3.2.1) [bacillibactin] siderophore Isochorismate synthase (EC 5.4.4.2) [bacillibactin] siderophore Trilactone hydrolase [bacillibactin] siderophore Iron_siderophore_sensor_&_receptor_system FIG006045: Sigma factor, ECF subfamily Iron siderophore receptor protein Iron siderophore sensor protein Petrobactin-mediated_iron_uptake_system Petrobactin ABC transporter, ATP-binding protein Petrobactin ABC transporter, periplasmic binding protein Petrobactin ABC transporter, permease protein I Petrobactin ABC transporter, permease protein II Salmochelin-mediated_Iron_Acquisition ABC transporter protein IroC Glycosyltransferase IroB Outer Membrane Siderophore Receptor IroN Periplasmic esterase IroE Trilactone hydrolase IroD Siderophore_Achromobactin Achromobactin biosynthesis protein AcsA Achromobactin biosynthesis protein AcsB, HpcH/HpaI aldolase family Achromobactin biosynthesis protein AcsC Achromobactin biosynthesis protein AcsD Achromobactin biosynthesis protein AcsE, Orn/DAP/Arg decarboxylase family Achromobactin biosynthesis protein AcsF Outer membrane receptor proteins, likely involved in siderophore uptake Permease of the major facilitator superfamily in achromobactin biosynthesis operon Permease of the major facilitator superfamily in uncharacterized siderophore S biosynthesis operon Probable Lysine n(6)-hydroxylase associated with siderophore S biosynthesis (EC 1.14.13.59) Putative achromobactin biosynthesis protein, related to 2-demethylmenaquinone methyltransferase Putative siderophore biosynthesis protein, related to 2-demethylmenaquinone methyltransferase Siderophore achromobactin ABC transporter, ATPase component Siderophore achromobactin ABC transporter, permease protein Siderophore achromobactin ABC transporter, substrate-binding protein TonB-dependent ferric achromobactin receptor protein Uncharacterized Fe-S protein in siderophore biosynthesis operon Uncharacterized siderophore S biosynthesis AcsA-like protein Uncharacterized siderophore S biosynthesis protein, AcsC-like Uncharacterized siderophore S biosynthesis protein, AcsD-like Siderophore_Aerobactin Aerobactin siderophore receptor IutA Citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase, alpha subunit (EC 6.3.2.27), aerobactin biosynthesis protein IucA Ferric aerobactin ABC transporter, ATPase component Ferric aerobactin ABC transporter, periplasmic substrate binding protein Ferric aerobactin ABC transporter, permease component Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB Ferric hydroxamate outer membrane receptor FhuA L-lysine 6-monooxygenase [NADPH] (EC 1.14.13.59), aerobactin biosynthesis protein IucD N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102), aerobactin biosynthesis protein IucB Transcriptional repressor of aerobactin receptor iutR Siderophore_Desferrioxamine_E Desferrioxamine E biosynthesis protein DesA Desferrioxamine E biosynthesis protein DesB Desferrioxamine E biosynthesis protein DesC Desferrioxamine E biosynthesis protein DesD Hypothetical protein associated with desferrioxamine E biosynthesis Putative Desferrioxamine E transporter Siderophore_Enterobactin 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) [enterobactin] siderophore 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [enterobactin] siderophore 4'-phosphopantetheinyl transferase (EC 2.7.8.-) [enterobactin] siderophore Apo-aryl carrier domain of EntB Enterobactin esterase Enterobactin exporter EntS Enterobactin synthetase component F, serine activating enzyme (EC 2.7.7.-) FIG005032: Putative cytoplasmic protein YbdZ in enterobactin biosynthesis operon Ferric enterobactin transport ATP-binding protein FepC (TC 3.A.1.14.2) Ferric enterobactin transport system permease protein FepD (TC 3.A.1.14.2) Ferric enterobactin transport system permease protein FepG (TC 3.A.1.14.2) Ferric enterobactin uptake protein FepE Ferric enterobactin-binding periplasmic protein FepB (TC 3.A.1.14.2) Isochorismatase (EC 3.3.2.1) [enterobactin] siderophore Isochorismate synthase (EC 5.4.4.2) [enterobactin] siderophore Outer membrane receptor for ferric enterobactin PfeA Outer membrane receptor for ferric enterobactin and colicins B, D Proofreading thioesterase in enterobactin biosynthesis EntH Transcriptional regulator of AraC family, enterobactin-dependent, predicted Two-component response regulator PfeR, enterobactin Two-component sensor histidine kinase PfeS, enterobactin Siderophore_Pyoverdine ABC transporter in pyoverdin gene cluster, ATP-binding component ABC transporter in pyoverdin gene cluster, periplasmic component ABC transporter in pyoverdin gene cluster, permease component Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching Antisigma transmembrane sensor FpvR Cation ABC transporter, periplasmic cation-binding protein, PA2407 homolog Hypothetical MbtH-like protein, PA2412 homolog Hypothetical protein PvdX Hypothetical protein PvdY Hypothetical protein in pyoverdin gene cluster Hypothetical protein in pyoverdin gene cluster, PA2405 homolog Hypothetical protein in pyoverdin gene cluster, PA2406 homolog L-ornithine 5-monooxygenase (EC 1.13.12.-), PvdA of pyoverdin biosynthesis Non-ribosomal peptide synthetase modules, pyoverdine Non-ribosomal peptide synthetase modules, pyoverdine?? Outer membrane ferripyoverdine receptor Outer membrane ferripyoverdine receptor FpvA, TonB-dependent Outer membrane ferripyoverdine receptor FpvB, for Type I pyoverdine Outer membrane porin, coexpressed with pyoverdine biosynthesis regulon Outer membrane pyoverdine eflux protein Pirin-related protein, coexpressed with pyoverdine biosynthesis regulon Probable hydrolase, coexpressed with pyoverdine biosynthesis regulon Probable thioesterase involved in non-ribosomal peptide biosynthesis, PA2411 homolog Putative dipeptidase, pyoverdin biosynthesis PvdM Putative iron-regulated membrane protein, PA2403 homolog Putative thiamine pyrophosphate-requiring enzyme, PA2404 homolog PvdE, pyoverdine ABC export system, fused ATPase and permease components PvdO, pyoverdine responsive serine/threonine kinase (predicted by OlgaV) Pyoverdin biosynthesis protein PvdH, L-2,4-diaminobutyrate:2-oxoglutarate aminotransferase (EC 2.6.1.76) Pyoverdin biosynthesis protein PvdN, putative aminotransferase, class V Pyoverdine biosynthesis related protein PvdP Pyoverdine chromophore precursor synthetase PvdL Pyoverdine efflux carrier and ATP binding protein Pyoverdine sidechain non-ribosomal peptide synthetase PvdD Pyoverdine sidechain non-ribosomal peptide synthetase PvdI Pyoverdine sidechain non-ribosomal peptide synthetase PvdJ Pyoverdine synthetase PvdF, N5-hydroxyornithine formyltransferase Sigma factor PvdS, controling pyoverdin biosynthesis Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis Thioesterase PvdG involved in non-ribosomal peptide biosynthesis pyoverdine-specific efflux macA-like protein Siderophore_Staphylobactin Siderophore staphylobactin ABC transporter, ATP-binding protein, putative Siderophore staphylobactin ABC transporter, permease protein SirB Siderophore staphylobactin ABC transporter, permease protein SirB, putative Siderophore staphylobactin ABC transporter, permease protein SirC Siderophore staphylobactin ABC transporter, permease protein SirC, putative Siderophore staphylobactin ABC transporter, substrate-binding protein SirA Siderophore staphylobactin ABC transporter, substrate-binding protein SirA, putative Siderophore staphylobactin biosynthesis protein SbnA Siderophore staphylobactin biosynthesis protein SbnB Siderophore staphylobactin biosynthesis protein SbnC Siderophore staphylobactin biosynthesis protein SbnD Siderophore staphylobactin biosynthesis protein SbnE Siderophore staphylobactin biosynthesis protein SbnF Siderophore staphylobactin biosynthesis protein SbnG Siderophore staphylobactin biosynthesis protein SbnH Siderophore staphylobactin biosynthesis protein SbnI Siderophore_Yersiniabactin_Biosynthesis iron aquisition 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58,Irp5) iron aquisition outermembrane yersiniabactin receptor (FyuA,Psn,pesticin receptor) iron aquisition regulator (YbtA,AraC-like,required for transcription of FyuA/psn,Irp2) iron aquisition yersiniabactin synthesis enzyme (Irp1,polyketide synthetase) iron aquisition yersiniabactin synthesis enzyme (Irp2) iron aquisition yersiniabactin synthesis enzyme (Irp3) iron aquisition yersiniabactin synthesis enzyme (YbtT,resembles thioesterases) Siderophore_[Alcaligin-like] Iron-siderophore [Alcaligin-like] ferric reductase (1.6.99.14) Iron-siderophore [Alcaligin-like] receptor Iron-siderophore [Alcaligin-like] transport system, ATP-binding component Iron-siderophore [Alcaligin-like] transport system, permease component Iron-siderophore [Alcaligin-like] transport system, substrate-binding component Iron-siderophore [Alcaligin-like] transport system, transmembran component Siderophore [Alcaligin-like] biosynthesis complex, long chain Siderophore [Alcaligin-like] biosynthesis complex, medium chain Siderophore [Alcaligin-like] biosynthesis complex, short chain Siderophore [Alcaligin-like] biosynthetic enzyme (EC 1.14.13.59) Siderophore [Alcaligin-like] decarboxylase (EC 4.1.1.-) Siderophore_assembly_kit 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) of siderophore biosynthesis ABC-type Fe3+-siderophore transport system, ATPase component ABC-type Fe3+-siderophore transport system, periplasmic iron-binding component ABC-type Fe3+-siderophore transport system, permease 2 component ABC-type Fe3+-siderophore transport system, permease component ABC-type hemin transport system, ATPase component Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB Ferric hydroxamate outer membrane receptor FhuA Ferric reductase (1.6.99.14) Hemin ABC transporter, permease protein Hemin transport protein HmuS Iron-siderophore transport system, ATP-binding component Iron-siderophore transport system, permease component Iron-siderophore transport system, substrate-binding component Iron-siderophore transport system, transmembran component Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis Long-chain-fatty-acid--CoA ligase of siderophore biosynthesis Periplasmic hemin-binding protein Siderophore biosynthesis L-2,4-diaminobutyrate decarboxylase Siderophore biosynthesis diaminobutyrate--2-oxoglutarate aminotransferase (EC 2.6.1.76) Siderophore biosynthesis non-ribosomal peptide synthetase modules Siderophore biosynthesis protein, monooxygenase Siderophore related permease Siderophore synthetase component, ligase Siderophore synthetase large component, acetyltransferase Siderophore synthetase small component, acetyltransferase Siderophore transport protein TonB-dependent hemin , ferrichrome receptor TonB-dependent hemin receptor TonB-dependent siderophore receptor Siderophore_pyochelin 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [enantio-pyochelin] siderophore 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [pyochelin] siderophore ABC efflux pump, fused inner membrane and ATPase subunits in pyochelin gene cluster Dihydroaeruginoate synthetase PchE, non-ribosomal peptide synthetase modules Enantio-pyochelin biosynthetic protein PchC, predicted thioesterase Enantio-pyochelin biosynthetic protein PchK, putative reductoisomerase Enantio-pyochelin synthetase PchF, non-ribosomal peptide synthetase module Ferric enantio-pyochelin transport system ATP-binding protein Ferric enantio-pyochelin transport system periplasmic substrate-binding protein Ferric enantio-pyochelin transport system permease protein Hypothetical protein FtpB in pyochelin gene cluster Inner-membrane permease FptX, ferripyochelin Isochorismate pyruvate-lyase (EC 4.-.-.-) [enantio-pyochelin] siderophore Isochorismate pyruvate-lyase (EC 4.-.-.-) [pyochelin] siderophore Isochorismate synthase (EC 5.4.4.2) [enantio-pyochelin] siderophore Isochorismate synthase (EC 5.4.4.2) [pyochelin] siderophore Outer membrane receptor for ferric enantio-pyochelin Outer membrane receptor for ferric-pyochelin FptA Probable MFS transporter in enantio-pyochelin gene cluster Putative iron-regulated membrane protein FtpC in pyochelin gene cluster Pyochelin biosynthetic protein PchC, predicted thioesterase Pyochelin biosynthetic protein PchG, oxidoreductase (NAD-binding) Pyochelin synthetase PchF, non-ribosomal peptide synthetase module Transcriptional regulator PchR Vibrioferrin_synthesis Ferric siderophore receptor PsuA Ferrichrome ABC transporter (ATP binding subunit) PvuE Ferrichrome ABC transporter (permease) PvuC Ferrichrome ABC transporter (permease) PvuD Ferrichrome ABC transporter, periplasmic iron-binding protein PvuB Vibrioferrin amide bond forming protein PvsB Vibrioferrin amide bond forming protein PvsD Vibrioferrin decarboxylase protein PvsE Vibrioferrin ligase/carboxylase protein PvsA Vibrioferrin membrane-spanning transport protein PvsC Vibrioferrin receptor PvuA 02 Campylobacter_Iron_Metabolism Enterochelin uptake ATP-binding protein Enterochelin uptake periplasmic binding protein Enterochelin uptake permease CeuB Enterochelin uptake permease CeuC Ferric iron ABC transporter, iron-binding protein Ferric iron ABC transporter, permease protein Ferric receptor CfrA Ferric siderophore transport system, biopolymer transport protein ExbB Ferric siderophore transport system, biopolymer transport protein ExbD Ferric siderophore transport system, periplasmic binding protein TonB Ferric uptake regulation protein Ferrous iron transport protein A, putative Ferrous iron transport protein B Haemin uptake system ATP-binding protein Haemin uptake system outer membrane receptor Haemin uptake system periplasmic haemin-binding protein Haemin uptake system permease protein Hemerythrin-like iron-binding protein Magnesium and cobalt transport protein CorA Nonheme iron-containing ferritin Periplasmic protein p19 involved in high-affinity Fe2+ transport Peroxide stress regulator Possible bacterioferritin Putative heme oxygenase Putative high-affinity iron permease Putative iron-uptake ABC transport system ATP-binding protein Putative lipoprotein of ferric iron transporter system Putative lipoprotein, similar to CjrA of Escherichia coli O164 Putative outer membrane siderophore receptor Ferrous_iron_transporter_EfeUOB,_low-pH-induced Ferrous iron transport periplasmic protein EfeO, contains peptidase-M75 domain and (frequently) cupredoxin-like domain Ferrous iron transport permease EfeU Ferrous iron transport permease EfeU, N-terminal extended Ferrous iron transport peroxidase EfeB Heme,_hemin_uptake_and_utilization_systems_in_GramPositives Acyl carrier protein associated with anthrachelin biosynthesis Antibiotic biosynthesis monooxygenase domain-containing protein Cell surface protein IsdA, transfers heme from hemoglobin to apo-IsdC Cell surface protein IsdA1 Cell surface protein Shp, transfers heme from hemoglobin to apo-SiaA/HtsA Cell surface receptor IsdB for hemoglobin and hemoglobin-haptoglobin complexes Cell surface receptor IsdH for hemoglobin-haptoglobin complexes Heme ABC transporter (Streptococcus), ATP-binding protein Heme ABC transporter (Streptococcus), heme and hemoglobin-binding protein SiaA/HtsA Heme ABC transporter (Streptococcus), permease protein Heme ABC transporter, ATPase component HmuV Heme ABC transporter, cell surface heme and hemoprotein receptor HmuT Heme ABC transporter, permease protein HmuU Heme ABC type transporter HtsABC, heme-binding protein Heme ABC type transporter HtsABC, permease protein HtsB Heme ABC type transporter HtsABC, permease protein HtsC Heme efflux system ATPase HrtA Heme efflux system permease HrtB Heme oxygenase (EC 1.14.99.3) Heme oxygenase HemO, associated with heme uptake Heme transporter IsdDEF, lipoprotein IsdE Heme transporter IsdDEF, membrane component IsdD Heme transporter IsdDEF, permease component IsdF Heme transporter analogous to IsdDEF, ATP-binding protein Heme-degrading cytoplasmic oxygenase IsdG Heme-degrading cytoplasmic oxygenase IsdI Hemin transport protein HmuS Hemoglobin, heme-dependent two component system response regulator ChrA Hemoglobin, heme-dependent two component system sensory histidine kinase ChrS Hemoglobin-dependent two component system response regulator HrrA Hemoglobin-dependent two component system, sensory histidine kinase HrrS Hypothetical protein DUF454 Hypothetical protein GBAA1985 associated with anthrachelin biosynthesis, unique Hypothetical protein GBAA1986 associated with anthrachelin biosynthesis, isomerase-like TIM barrel domain Hypothetical similar to CcmC, putative heme lyase for CcmE Hypothetical, distant similarity with heme-degrading oxygenase IsdG Iron compound ABC uptake transporter ATP-binding protein Iron compound ABC uptake transporter ATP-binding protein PiaD Iron compound ABC uptake transporter ATP-binding protein PiuD Iron compound ABC uptake transporter permease protein Iron compound ABC uptake transporter permease protein PiaB Iron compound ABC uptake transporter permease protein PiaC Iron compound ABC uptake transporter permease protein PiuB Iron compound ABC uptake transporter permease protein PiuC Iron compound ABC uptake transporter substrate-binding protein Iron compound ABC uptake transporter substrate-binding protein PiaA Iron compound ABC uptake transporter substrate-binding protein PiuA Iron-dependent repressor IdeR/DtxR LPXTG specific sortase A Long-chain-fatty-acid--CoA ligase associated with anthrachelin biosynthesis Metallo-beta-lactamase superfamily domain protein in prophage NPQTN cell wall anchored protein IsdC NPQTN specific sortase B Putative ABC transporter (ATP-binding protein), spy1791 homolog Putative ABC transporter ATP-binding protein, spy1790 homolog Putative siderophore biosynthesis protein GBAA1981 Putative siderophore biosynthesis protein GBAA1982 Sensor histidine kinase colocalized with HrtAB transporter Similar to hypothetical protein DUF454 Sortase A, LPXTG specific Streptococcal cell surface hemoprotein receptor Shr Two-component response regulator SA14-24 Two-component response regulator colocalized with HrtAB transporter Two-component sensor kinase SA14-24 Uncharacterized iron compound ABC uptake transporter, ATP-binding protein Uncharacterized iron compound ABC uptake transporter, permease protein Uncharacterized iron compound ABC uptake transporter, substrate-binding protein Zn-dependent hydrolase (beta-lactamase superfamily) Hemin_transport_system ABC-type hemin transport system, ATPase component Biopolymer transport protein ExbD1 Ferric siderophore transport system, periplasmic binding protein TonB Haemin uptake system ATP-binding protein Haemin uptake system outer membrane receptor Haemin uptake system periplasmic haemin-binding protein Haemin uptake system permease protein Heme oxygenase HemO, associated with heme uptake Hemin ABC transporter, permease protein Hemin receptor protein HemR Hemin transport protein Hemin transport protein HmuS Hemin uptake protein Hemin uptake protein HemP Hemin-binding lipoprotein HbpA Iron compound ABC uptake transporter ATP-binding protein Outer membrane hemoglobin utilization protein HmbR Outer membrane hemoglobin-haptoglobin utilization protein HpuB Outer membrane receptor proteins, mostly Fe transport Periplasmic hemin-binding protein Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein TonB-dependent hemin , ferrichrome receptor heme uptake regulator heme uptake transmembrane sensor Iron_Scavenging_cluster_in_Thermus FIG078613: hypothetical protein in iron scavenging cluster Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3) Heme ABC transporter, ATPase component HmuV Heme ABC transporter, cell surface heme and hemoprotein receptor HmuT Heme ABC transporter, permease protein HmuU Heme-degrading oxygenase, IsdG-like Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites hypothetical protein in Thermus iron scavenging cluster Iron_acquisition_in_Streptococcus Ferric iron ABC transporter, ATP-binding protein Ferric iron ABC transporter, iron-binding protein Ferric iron ABC transporter, permease protein Iron compound ABC uptake transporter ATP-binding protein Iron compound ABC uptake transporter permease protein Iron compound ABC uptake transporter substrate-binding protein Two-component response regulator, associated with ferric iron transporter, SPy1062 homolog Two-component sensor kinase, associated with ferric iron transporter, SPy1061 homolog Iron_acquisition_in_Vibrio 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) Aerobactin siderophore receptor IutA Amide synthase component of siderophore synthetase Bacterioferritin Bacterioferritin-associated ferredoxin Catechol siderophore ABC transporter, ATP-binding component Catechol siderophore ABC transporter, permease component Catechol siderophore ABC transporter, substrate-binding protein Enterobactin receptor IrgA Enterobactin receptor VctA Ferric aerobactin ABC transporter, ATPase component Ferric aerobactin ABC transporter, periplasmic substrate binding protein Ferric aerobactin ABC transporter, permease component Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB Ferric hydroxamate outer membrane receptor FhuA Ferric iron ABC transporter, ATP-binding protein Ferric iron ABC transporter, iron-binding protein Ferric iron ABC transporter, permease protein Ferric uptake regulation protein FUR Ferric vibriobactin receptor ViuA Ferric vibriobactin, enterobactin transport system, ATP-binding protein (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, ATP-binding protein ViuC (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, permease protein VctD (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, permease protein VctG (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, permease protein ViuD (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, permease protein ViuG (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, substrate-binding protein VctP (TC 3.A.1.14.6) Ferric vibriobactin, enterobactin transport system, substrate-binding protein ViuP (TC 3.A.1.14.6) Ferric vulnibactin receptor VuuA Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3) Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3) Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3) Ferrichrome-iron receptor Ferrous iron transport protein A Ferrous iron transport protein B Ferrous iron transport protein C Hemin ABC transporter, permease protein Hypothetical protein colocalized with Enterobactin receptor VctA Hypothetical protein in aerobactin uptake cluster Iron-regulated virulence regulatory protein irgB Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis Isochorismate pyruvate-lyase of siderophore biosynthesis Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis Non-ribosomal peptide synthetase modules, siderophore biosynthesis Phosphopantetheinyl transferase component of siderophore synthetase (EC 2.7.8.-) Putative TonB-dependent heme receptor HasR Putative heme iron utilization protein Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein Regulatory small RNA involved in iron homeostasis RyhB TonB-dependent heme and hemoglobin receptor HutA TonB-dependent heme receptor HutR TonB-dependent receptor Transcriptional regulator near Vibriobactin biosynthetic gene custer Transcriptional regulator, VCA0231 ortholog Transcriptional repressor of aerobactin receptor iutR Utilization protein for unknown catechol-siderophore X Vibriobactin utilization protein ViuB Vulnibactin utilization protein VuuB Transport_of_Iron Chlorophyll a(b) binding protein, photosystem II CP43 protein (PsbC) homolog Ferric iron ABC transporter, ATP-binding protein Ferric iron ABC transporter, iron-binding protein Ferric iron ABC transporter, permease protein Ferric uptake regulation protein FUR Ferrichrome-iron receptor Ferrous iron transport protein A Ferrous iron transport protein B Ferrous iron-sensisng transcriptional regulator FeoC Iron-dependent repressor IdeR/DtxR Iron-regulated protein A precursor Iron-responsive regulator Irr Iron-uptake factor PiuB Iron-uptake factor PiuC Periplasmic protein p19 involved in high-affinity Fe2+ transport Putative high-affinity iron permease 01 Membrane Transport 02 ABC transporters ABC_transporter_alkylphosphonate_(TC_3.A.1.9.1) Phosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1) Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1) Phosphonate ABC transporter permease protein phnE1 (TC 3.A.1.9.1) Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) ABC_transporter_branched-chain_amino_acid_(TC_3.A.1.4.1) Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) High-affinity leucine-specific transport system, periplasmic binding protein LivK (TC 3.A.1.4.1) ABC_transporter_dipeptide_(TC_3.A.1.5.2) Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) ABC_transporter_of_unknown_substrate_X Possible ABC transporter, periplasmic substrate X binding protein precursor Putative ABC transporter of substrate X, ATP-binding subunit Putative ABC transporter of substrate X, permease subunit I Putative ABC transporter of substrate X, permease subunit II ABC_transporter_oligopeptide_(TC_3.A.1.5.1) Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1) Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1) Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1) ABC_transporter_peptide_(TC_3.A.1.5.5) Peptide transport periplasmic protein sapA (TC 3.A.1.5.5) Peptide transport system ATP-binding protein SapD (TC 3.A.1.5.5) Peptide transport system ATP-binding protein sapF (TC 3.A.1.5.5) Peptide transport system permease protein sapB (TC 3.A.1.5.5) Peptide transport system permease protein sapC (TC 3.A.1.5.5) ABC_transporter_tungstate_(TC_3.A.1.6.2) ABC-type tungstate transport system, ATP-binding protein ABC-type tungstate transport system, periplasmic binding protein ABC-type tungstate transport system, permease protein ABC-type vanadate transport system, ATP-binding protein ABC-type vanadate transport system, periplasmic binding protein ABC-type vanadate transport system, permease protein ATP-dependent_efflux_pump_transporter_Ybh ABC transport system, permease component YbhR ABC transport system, permease component YbhS ABC transporter multidrug efflux pump, fused ATP-binding domains Predicted membrane fusion protein (MFP) component of efflux pump, membrane anchor protein YbhG Transcriptional regulator YbiH, TetR family Periplasmic-Binding-Protein-Dependent_Transport_System_for_α-Glucosides ABC alpha-glucoside transporter, inner membrane subunit AglF Alpha-glucosidase AglA Alpha-glucoside transport ATP-binding protein AglK Alpha-glucoside transport system permease protein AglG Alpha-glucosides-binding periplasmic protein AglE precursor Transcriptional regulator AglR, LacI family 02 Protein and nucleoprotein secretion system, Type IV Dot-Icm_type_IV_secretion_system DotA protein DotB protein DotC protein DotD IcmB (DotO) protein IcmC (DotE) protein IcmD (DotP) protein IcmE (DotG) protein IcmF protein IcmG protein IcmJ (DotN) protein IcmK (DotH) protein IcmL (DotI) protein IcmO (DotL) protein IcmP (DotM) protein IcmQ protein IcmR protein IcmS protein IcmT protein IcmV protein IcmW protein IcmX protein Mannose-sensitive_hemagglutinin_type_4_pilus MSHA biogenesis protein MshE MSHA biogenesis protein MshF MSHA biogenesis protein MshF2 MSHA biogenesis protein MshG MSHA biogenesis protein MshH MSHA biogenesis protein MshI MSHA biogenesis protein MshJ MSHA biogenesis protein MshK MSHA biogenesis protein MshK2 MSHA biogenesis protein MshK3 MSHA biogenesis protein MshL MSHA biogenesis protein MshM MSHA biogenesis protein MshN MSHA biogenesis protein MshO MSHA biogenesis protein MshP MSHA biogenesis protein MshQ MSHA pilin protein MshA MSHA pilin protein MshB MSHA pilin protein MshC MSHA pilin protein MshD Toxin_co-regulated_pilus TCP pilin signal peptidase, TcpA processing TCP pilus virulence regulatory protein ToxT, transcription activator Toxin co-regulated pilin A Toxin co-regulated pilus biosynthesis protein B Toxin co-regulated pilus biosynthesis protein C, outer membrane protein Toxin co-regulated pilus biosynthesis protein D Toxin co-regulated pilus biosynthesis protein E, anchors TcpT to membrane Toxin co-regulated pilus biosynthesis protein F, putative outer membrane channel for TcpA extrusion Toxin co-regulated pilus biosynthesis protein H, transcriptional activator of ToxT promoter Toxin co-regulated pilus biosynthesis protein I, chemoreceptor, negative regulator of TcpA Toxin co-regulated pilus biosynthesis protein P, transcriptional activator of ToxT promoter Toxin co-regulated pilus biosynthesis protein Q Toxin co-regulated pilus biosynthesis protein R Toxin co-regulated pilus biosynthesis protein S Toxin co-regulated pilus biosynthesis protein T, putative ATP-binding translocase of TcpA Type_4_conjugative_transfer_system,_IncI1_type IncI1 plasmid conjugative transfer ATPase PilQ IncI1 plasmid conjugative transfer DNA primase IncI1 plasmid conjugative transfer NusG-type transcription antiterminator TraB IncI1 plasmid conjugative transfer inner membrane protein PilR IncI1 plasmid conjugative transfer integral membrane protein TraY IncI1 plasmid conjugative transfer lipoprotein PilN IncI1 plasmid conjugative transfer pilus-tip adhesin protein PilV IncI1 plasmid conjugative transfer prepilin PilS IncI1 plasmid conjugative transfer protein PilI IncI1 plasmid conjugative transfer protein PilJ IncI1 plasmid conjugative transfer protein PilK IncI1 plasmid conjugative transfer protein PilL IncI1 plasmid conjugative transfer protein PilM IncI1 plasmid conjugative transfer protein TraA IncI1 plasmid conjugative transfer protein TraC IncI1 plasmid conjugative transfer protein TraE IncI1 plasmid conjugative transfer protein TraF IncI1 plasmid conjugative transfer protein TraG IncI1 plasmid conjugative transfer protein TraH IncI1 plasmid conjugative transfer protein TraI IncI1 plasmid conjugative transfer protein TraJ, related to pilus biogenesis/retracton protein IncI1 plasmid conjugative transfer protein TraK IncI1 plasmid conjugative transfer protein TraL IncI1 plasmid conjugative transfer protein TraM IncI1 plasmid conjugative transfer protein TraN IncI1 plasmid conjugative transfer protein TraO IncI1 plasmid conjugative transfer protein TraP IncI1 plasmid conjugative transfer protein TraQ IncI1 plasmid conjugative transfer protein TraR IncI1 plasmid conjugative transfer protein TraS IncI1 plasmid conjugative transfer protein TraT IncI1 plasmid conjugative transfer protein TraU IncI1 plasmid conjugative transfer protein TraV IncI1 plasmid conjugative transfer protein TraW IncI1 plasmid conjugative transfer protein TraX IncI1 plasmid conjugative transfer putative membrane protein PilT IncI1 plasmid pilus assembly protein PilO IncI1 plasmid pilus assembly protein PilP Plasmid conjugative transfer endonuclease Shufflon-specific DNA recombinase Type-IV sectretion leader peptidase/N-methyltransferase Type_IV_pilus 3-dehydroquinate synthase (EC 4.2.3.4) Fimbrial assembly protein FimB Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) N-methyltransferase (EC 2.1.1.-) PilS cassette Twitching motility protein PilT Two-component sensor PilS Type IV fimbriae expression regulatory protein PilR Type IV fimbrial assembly protein PilC Type IV fimbrial assembly, ATPase PilB Type IV fimbrial biogenesis protein FimT Type IV fimbrial biogenesis protein PilV Type IV fimbrial biogenesis protein PilW Type IV fimbrial biogenesis protein PilX Type IV fimbrial biogenesis protein PilY1 Type IV fimbrial biogenesis protein PilY2 Type IV pilin PilA Type IV pilus biogenesis protein PilE Type IV pilus biogenesis protein PilM Type IV pilus biogenesis protein PilN Type IV pilus biogenesis protein PilO Type IV pilus biogenesis protein PilP Type IV pilus biogenesis protein PilQ type 4 fimbrial biogenesis protein FimU pVir_Plasmid_of_Campylobacter ATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB11) ATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB4) DNA topoisomerase I (EC 5.99.1.2) Hypothetical protein pVir0004 Hypothetical protein pVir0007 Hypothetical protein pVir0008 Hypothetical protein pVir0009 Hypothetical protein pVir0010 Hypothetical protein pVir0012 Hypothetical protein pVir0015 Hypothetical protein pVir0016 Hypothetical protein pVir0019/pVir0020 Hypothetical protein pVir0021 Hypothetical protein pVir0029, glutamine-rich Hypothetical protein pVir0042 Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB8) Plasmid partitioning protein ParA Single-stranded DNA-binding protein Type IV secretion system protein VirD4 Type IV secretion/competence protein (VirB10) Type IV secretion/competence protein (VirB9) 02 Protein secretion system, Type II General_Secretion_Pathway General secretion pathway protein A General secretion pathway protein B General secretion pathway protein C General secretion pathway protein D General secretion pathway protein E General secretion pathway protein F General secretion pathway protein G General secretion pathway protein H General secretion pathway protein I General secretion pathway protein J General secretion pathway protein K General secretion pathway protein L General secretion pathway protein M General secretion pathway protein N General secretion pathway protein O Widespread_colonization_island ATP-dependent helicase, DEAD/DEAH box family, associated with Flp pilus assembly ATPase with chaperone activity, associated with Flp pilus assembly Flp pilus assembly membrane protein TadE Flp pilus assembly protein CpaD Flp pilus assembly protein RcpB Flp pilus assembly protein RcpC/CpaB Flp pilus assembly protein TadB Flp pilus assembly protein TadD, contains TPR repeat Flp pilus assembly protein, pilin Flp Flp pilus assembly surface protein TadF, ATP/GTP-binding motif Predicted ATPase with chaperone activity, associated with Flp pilus assembly Protein TadG, associated with Flp pilus assembly Similar to TadZ/CpaE, associated with Flp pilus assembly Similar to secretin RcpA/CpaC, associated with Flp pilus assembly Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily Type II/IV secretion system ATPase TadZ/CpaE, associated with Flp pilus assembly Type II/IV secretion system protein TadC, associated with Flp pilus assembly Type II/IV secretion system secretin RcpA/CpaC, associated with Flp pilus assembly Type IV prepilin peptidase TadV/CpaA Von Willebrand factor type A domain protein, associated with Flp pilus assembly 02 Protein secretion system, Type III Type_III_secretion_system Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) Type III secretion chaperone protein for YopD (SycD) Type III secretion chaperone protein for YopE (SycE) Type III secretion chaperone protein for YopH (SycH) Type III secretion chaperone protein for YopN (SycN,YscB) Type III secretion chaperone protein for YopT (SycT) Type III secretion cytoplasmic ATP synthase (EC 3.6.3.14, YscN,SpaL,MxiB,HrcN,EscN) Type III secretion cytoplasmic LcrG inhibitor (LcrV,secretion and targeting control protein, V antigen) Type III secretion cytoplasmic plug protein (LcrG) Type III secretion cytoplasmic protein (YscF) Type III secretion cytoplasmic protein (YscI) Type III secretion cytoplasmic protein (YscK) Type III secretion cytoplasmic protein (YscL) Type III secretion effector protein (YopR, encoded by YscH) Type III secretion host injection and negative regulator protein (YopD) Type III secretion host injection protein (YopB) Type III secretion injected virulence protein (EC 3.4.22.-,YopT,cysteine protease,depolymerizes actin filaments of cytoskeleton,causes cytotoxicity) Type III secretion injected virulence protein (YopE) Type III secretion injected virulence protein (YopH,tyrosine phosphatase of FAK and p130cas, prevents phagocytosis) Type III secretion injected virulence protein (YopO,YpkA,serine-threonine kinase) Type III secretion injected virulence protein (YopP,YopJ, induces apoptosis, prevents cytokine induction, inhibits NFkb activation) Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) Type III secretion inner membrane protein (YscD,homologous to flagellar export components) Type III secretion inner membrane protein (YscQ,homologous to flagellar export components) Type III secretion inner membrane protein (YscR,SpaR,HrcR,EscR,homologous to flagellar export components) Type III secretion inner membrane protein (YscS,homologous to flagellar export components) Type III secretion inner membrane protein (YscT,HrcT,SpaR,EscT,EpaR1,homologous to flagellar export components) Type III secretion inner membrane protein (YscU,SpaS,EscU,HrcU,SsaU, homologous to flagellar export components) Type III secretion low calcium response protein (LcrR) Type III secretion negative modulator of injection (YopK,YopQ,controls size of translocator pore) Type III secretion negative regulator of effector production protein (LcrQ,YscM, YscM1 and YscM2) Type III secretion outermembrane contact sensing protein( yopN,Yop4b,LcrE) Type III secretion outermembrane negative regulator of secretion (TyeA) Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG) Type III secretion possible injected virulence protein (YopM) Type III secretion protein (YscA) Type III secretion protein (YscE) Type III secretion protein (YscP) Type III secretion spans bacterial envelope protein (YscG) Type III secretion spans bacterial envelope protein (YscO) Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) Type III secretion transporter lipoprotein (YscW,VirG) Type_III_secretion_system_orphans BarA sensory histidine kinase (= VarS = GacS) BarA-associated response regulator UvrY (= GacA = SirA) Flagellar regulon repressor RtsB OrgB protein, associated with InvC ATPase of type III secretion system Putative effector protein OrgC of SPI-1 type III secretion system SPI1-associated transcriptional regulator SprB Type III secretion and flagellar regulator RtsA Type III secretion transcriptional activator HilA Type III secretion transcriptional regulator HilC (= SirC) Type III secretion transcriptional regulator HilD 02 Protein secretion system, Type VI Type_VI_secretion_systems ClpB protein IcmF-related protein Inner membrane protein DotU Outer membrane protein ImpK/VasF, OmpA/MotB domain Phosphoprotein phosphatase PppA Protein ImpG/VasA Protein of avirulence locus ImpE Protein phosphatase ImpM Secreted protein Hcp Serine/threonine protein kinase (EC 2.7.11.1) PpkA Serine/threonine-protein kinase ImpN involved in nitrogen fixation Sigma-54 dependent transcriptional regulator Type VI secretion lipoprotein/VasD Type VI secretion protein VasI Type VI secretion-related protein VasL Uncharacterized protein ImpA Uncharacterized protein ImpB Uncharacterized protein ImpC Uncharacterized protein ImpD Uncharacterized protein ImpF Uncharacterized protein ImpH/VasB Uncharacterized protein ImpI/VasC Uncharacterized protein ImpJ/VasE Uncharacterized protein homologous to Paeru. PA2364 Uncharacterized protein similar to VCA0109 VgrG protein VgrG-3 protein 02 Protein secretion system, Type VII (Chaperone/Usher pathway, CU) Colonization_factor_antigen_I_fimbriae CFA/I fimbrial auxiliary subunit CFA/I fimbrial chaperone CFA/I fimbrial major subunit CFA/I fimbrial minor adhesin CFA/I fimbrial subunit C usher protein FIGfam014588: Predicted regulator of CFA/I fimbriae The_fimbrial_Sfm_cluster Fimbriae-like adhesin FimI Fimbriae-like adhesin SfmA Fimbriae-like adhesin SfmH Fimbriae-like periplasmic protein SfmF Fimbrial periplasmic chaperone SfmC Outer membrane usher protein SfmD Transcriptional regulator of fimbriae expression FimY Transcriptional regulator of fimbriae expression FimZ (LuxR/UhpA family) The_fimbrial_Stf_cluster Fimbriae usher protein StfC Major fimbrial subunit StfA Minor fimbrial subunit StfE Minor fimbrial subunit StfF Minor fimbrial subunit StfG Periplasmic fimbrial chaperone StfD Uncharacterized protein YadU in stf fimbrial cluster The_usher_protein_HtrE_fimbrial_cluster Chaperone protein EcpD Fimbrial protein Yad-like Fimbrial protein YadC Fimbrial protein YadK Fimbrial protein YadL Fimbrial protein YadM Fimbrial protein YadM-like Fimbrial protein YadN Fimbrial protein YadN-like Outer membrane usher protein HtrE 02 Protein secretion system, Type VIII (Extracellular nucleation/precipitation pathway, ENP) Curli_production Curli production assembly/transport component CsgE Curli production assembly/transport component CsgF Curli production assembly/transport component CsgG Major curlin subunit precursor CsgA Minor curlin subunit CsgB, nucleation component of curlin monomers Putative curli production protein CsgC Transcriptional regulator CsgD for 2nd curli operon 02 Protein translocation across cytoplasmic membrane ESAT-6_proteins_secretion_system_in_Actinobacteria 10 kDa culture filtrate antigen CFP-10 (EsxB) 6 kDa early secretory antigenic target ESAT-6 (EsxA) AAA family ATPase, ESX-1 secretion system component Rv3868 FtsK/SpoIIIE family protein Rv3870, component of ESX-1 secretion system FtsK/SpoIIIE family protein Rv3871, component of ESX-1 secretion system Protein PE35, involved in regulation of esxAB expression Putative ESX-1 secretion system component Rv3869 Putative ESX-1 secretion system component Rv3877 Putative ESX-1 secretion system gating protein PPE68 RD1 region associated protein Rv3865 RD1 region associated protein Rv3866 RD1 region associated protein Rv3867 RD1 region associated protein Rv3876 RD1 region associated protein Rv3878 RD1 region associated protein Rv3879c ESAT-6_proteins_secretion_system_in_Firmicutes ESAT-6/Esx family secreted protein EsxA/YukE ESAT-6/Esx family secreted protein EsxB EsaC protein within ESAT-6 gene cluster (S.aureus type) FtsK/SpoIIIE family protein, putative secretion system component EssC/YukA Lmo0065 homolog within ESAT-6 gene cluster Lmo0066 homolog within ESAT-6 gene cluster, similarity to ADP-ribosylating toxins Lmo0069 homolog within ESAT-6 gene cluster Putative ESAT-secreted protein, BA2187 homolog Putative ESAT-secreted protein, BA2188 homolog Putative ESAT-secreted protein, BA2189 homolog Putative EsaC protein analog (Listeria type 1) Putative EsaC protein analog (Listeria type 2) Putative EsaC protein analog (Listeria type 3) Putative EsaC protein analog (Listeria type 4) Putative secretion accessory protein EsaA/YueB Putative secretion accessory protein EsaB/YukD Putative secretion system component EssA Putative secretion system component EssB/YukC Putative toxin component near putative ESAT-related proteins, repetitive Repetitive hypothetical protein in ESAT cluster, BH0979 homolog Repetitive hypothetical protein near ESAT cluster, SA0282 homolog SAG1025 homolog within ESAT-6 gene cluster SAV0291 homolog within ESAT-6 gene cluster Tetratrico-peptide repeat (TPR) protein within ESAT-6 gene cluster HtrA_and_Sec_secretion Peptidylproline cis-trans-isomerase (EC 5.2.1.8) Preprotein translocase secY subunit (TC 3.A.5.1.1) Preprotein translocase subunit SecE (TC 3.A.5.1.1) Preprotein translocase subunit SecG (TC 3.A.5.1.1) Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) Protein-export membrane protein SecD (TC 3.A.5.1.1) Protein-export membrane protein SecF (TC 3.A.5.1.1) Serine protease, DegP/HtrA, do-like (EC 3.4.21.-) SecY2-SecA2_Specialized_Transport_System Accessory secretory protein Asp1 Accessory secretory protein Asp2 Accessory secretory protein Asp3 GftB: Glycosyl transferase, family 8 Poly(glycerol-phosphate) alpha-glucosyltransferase GftA (EC 2.4.1.52) Preprotein translocase SecY2 subunit (TC 3.A.5.1.1) Protein export cytoplasm protein SecA2 ATPase RNA helicase (TC 3.A.5.1.1) Twin-arginine_translocation_system Deoxyribonuclease TatD Twin-arginine translocation protein TatA Twin-arginine translocation protein TatB Twin-arginine translocation protein TatC Twin-arginine translocation protein TatE 02 Sugar Phosphotransferase Systems, PTS Fructose_and_Mannose_Inducible_PTS Inducible Fructanase (EC 3.2.1.80), FruB PTS system, fructose- and mannose-inducible IIA component (EC 2.7.1.69) PTS system, fructose- and mannose-inducible IIB component (EC 2.7.1.69) PTS system, fructose- and mannose-inducible IIC component (EC 2.7.1.69) PTS system, fructose- and mannose-inducible IID component (EC 2.7.1.69) PTS system, fructose- and mannose-inducible putative EII component Phosphocarrier protein of PTS system Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) fructose response regulator of fruA and EII fructose/mannose fructose sensor histidine kinase periplasmic fructose-binding protein component of signal transduction system LevQ periplasmic fructose-binding protein component of signal transduction system LevT Galactose-inducible_PTS PTS system, galactose-inducible IIA component (EC 2.7.1.69) PTS system, galactose-inducible IIB component (EC 2.7.1.69) / PTS system, galactose-inducible IIC component (EC 2.7.1.69) Phosphocarrier protein of PTS system Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Phosphosugar-binding transcriptional repressor, RpiR family Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) Tagatose-6-phosphate kinase (EC 2.7.1.144) / 1-phosphofructokinase (EC 2.7.1.56) Sucrose-specific_PTS PTS system, sucrose-specific IIB component (EC 2.7.1.69) / PTS system, sucrose-specific IIC component (EC 2.7.1.69) / PTS system, sucrose-specific IIA component (EC 2.7.1.69) Phosphocarrier protein of PTS system Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Sucrose operon repressor ScrR, LacI family Sucrose-6-phosphate hydrolase (EC 3.2.1.26) 02 Uni- Sym- and Antiporters Na(+)_H(+)_antiporter Na+/H+ antiporter NhaA type Na+/H+ antiporter NhaD type Proton-dependent_Peptide_Transporters Di-/tripeptide transporter Di/tripeptide permease DtpA Di/tripeptide permease DtpB Di/tripeptide permease DtpT Di/tripeptide permease YbgH Di/tripeptide permease YjdL Sodium_Hydrogen_Antiporter Na(+) H(+) antiporter subunit A Na(+) H(+) antiporter subunit A (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit A (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit B Na(+) H(+) antiporter subunit B (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit B (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit C Na(+) H(+) antiporter subunit C (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit C (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit D Na(+) H(+) antiporter subunit D (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit D (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit E Na(+) H(+) antiporter subunit E (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit E (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit F Na(+) H(+) antiporter subunit F (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit F (TC 2.A.63.1.3) Na(+) H(+) antiporter subunit G Na(+) H(+) antiporter subunit G (TC 2.A.63.1.2) Na(+) H(+) antiporter subunit G (TC 2.A.63.1.3) 02 Agrobacterium_opine_transport LysR-type transcriptional regulator for nopaline catabolism NocR Nopaline transporter ATP-binding protein NocP Nopaline transporter periplasmic substrate-binding protein NocT Nopaline transporter permease protein NocM Nopaline transporter permease protein NocQ Choline_Transport Choline ABC transporter ATP-binding protein Choline ABC transporter permease protein Choline-binding lipoprotein Choline-sulfatase (EC 3.1.6.6) Sodium-Choline Symporter Citrate_Utilization_System_(CitAB,_CitH,_and_tctABC) CitH citrate transporter Response regulator CitB of citrate metabolism Signal transduction histidine kinase CitA regulating citrate metabolism TctA citrate transporter TctB citrate transporter TctC citrate transporter ECF_class_transporters ATPase component BioM of energizing module of biotin ECF transporter ATPase component CbiO of energizing module of cobalt ECF transporter ATPase component NikO of energizing module of nickel ECF transporter ATPase component STY3232 of energizing module of queuosine-regulated ECF transporter ATPase component STY3233 of energizing module of queuosine-regulated ECF transporter ATPase component of energizing module of predicted pantothenate ECF transporter ATPase component of energizing module of predicted queuosine-regulated ECF transporter ATPase component of general energizing module of ECF transporters Additional substrate-specific component CbiN of cobalt ECF transporter Additional substrate-specific component NikN of nickel ECF transporter Candidate substrate-specific domain of ECF transporters in Mycobacteria Duplicated ATPase component BL0693 of energizing module of predicted ECF transporter Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter Duplicated ATPase component Cce_1530 of energizing module of predicted ECF transporter Duplicated ATPase component Kcr_0336 of energizing module of predicted ECF transporter Duplicated ATPase component MTH454 of energizing module of predicted ECF transporter Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter Duplicated ATPase component SS1136 of energizing module of predicted ECF transporter Duplicated ATPase component TTE1589 of energizing module of predicted methylthioadenosine ECF transporter Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Duplicated ATPase component glr2054 of energizing module of predicted ECF transporter Duplicated ATPase component of energizing module of predicted B12-regulated ECF transporter for dimethylbenzimidazole Duplicated ATPase component of energizing module of predicted ECF transporter in Mycobacteria Duplicated ATPase component of energizing module of predicted pyridoxine-related ECF transporter Duplicated ATPase component of energizing module of predicted thiazole ECF transporter Duplicated ATPase component of energizing module of predicted tryptophan ECF transporter Duplicated ATPase component of energizing module of riboflavin ECF transporter Substrate-specific component BL0695 of predicted ECF transporter Substrate-specific component BioY of biotin ECF transporter Substrate-specific component CbiM of cobalt ECF transporter Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole Substrate-specific component CbrT of predicted cobalamin ECF transporter Substrate-specific component Cce_1529 of predicted ECF transporter Substrate-specific component FolT of folate ECF transporter Substrate-specific component Kcr_0335 of predicted ECF transporter Substrate-specific component MTH452 of predicted ECF transporter Substrate-specific component MtsA of methionine-regulated ECF transporter Substrate-specific component NiaX of predicted niacin ECF transporter Substrate-specific component NikM of nickel ECF transporter Substrate-specific component PAM0308 of predicted lipoate ECF transporter Substrate-specific component PanT of predicted pantothenate ECF transporter Substrate-specific component PdxU of predicted pyridoxine ECF transporter Substrate-specific component PdxU2 of predicted pyridoxin-related ECF transporter Substrate-specific component QueT (COG4708) of predicted queuosine-regulated ECF transporter Substrate-specific component RibU of riboflavin ECF transporter Substrate-specific component ST1137 of predicted ECF transporter Substrate-specific component STY3230 of queuosine-regulated ECF transporter Substrate-specific component TTE1586 of predicted methylthioadenosine ECF transporter Substrate-specific component ThiT of thiamin ECF transporter Substrate-specific component ThiW of predicted thiazole ECF transporter Substrate-specific component TrpP of tryptophan ECF transporter Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Substrate-specific component glr2052 of predicted ECF transporter Transmembrane component BL0694 of energizing module of predicted ECF transporter Transmembrane component BioN of energizing module of biotin ECF transporter Transmembrane component CbiQ of energizing module of cobalt ECF transporter Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter Transmembrane component Cce_1531 of energizing module of predicted ECF transporter Transmembrane component Kcr_0337 of energizing module of predicted ECF transporter Transmembrane component MTH453 of energizing module of predicted ECF transporter Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter Transmembrane component NikQ of energizing module of nickel ECF transporter Transmembrane component SS1135 of energizing module of predicted ECF transporter Transmembrane component STY3231 of energizing module of queuosine-regulated ECF transporter Transmembrane component TTE1588 of energizing module of predicted methylthioadenosine ECF transporter Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Transmembrane component glr2053 of energizing module of predicted ECF transporter Transmembrane component of energizing module of ECF transporters in Cyanobacteria Transmembrane component of energizing module of ECF transporters in Mycobacteria Transmembrane component of energizing module of predicted B12-regulated ECF transporter for dimethylbenzimidazole Transmembrane component of energizing module of predicted pantothenate ECF transporter Transmembrane component of energizing module of predicted pyridoxine-related ECF transporter Transmembrane component of energizing module of predicted queuosine-regulated ECF transporter Transmembrane component of energizing module of predicted tryptophan ECF transporter Transmembrane component of energizing module of riboflavin ECF transporter Transmembrane component of general energizing module of ECF transporters Phosphoglycerate_transport_system FIGfam009438: Two-component system DNA-binding response regulator FIGfam010146: Two component system histidine kinase FIGfam012970: transmembrane protein FIGfam013899: ABC transporter substrate-binding protein Phosphoglycerate transport regulatory protein PgtC Phosphoglycerate transport system sensor protein PgtB (EC 2.7.3.-) Phosphoglycerate transport system transcriptional regulatory protein PgtA Phosphoglycerate transporter protein PgtP Ton_and_Tol_transport_systems 4-hydroxybenzoyl-CoA thioesterase family active site Aerobactin siderophore receptor IutA Biopolymer transport ExbD protein Biopolymer transport protein ExbD/TolR Colicin I receptor precursor Ferric receptor CfrA Ferric siderophore transport system, biopolymer transport protein ExbB Ferric siderophore transport system, biopolymer transport protein ExbD Ferric siderophore transport system, periplasmic binding protein TonB Galactose-regulated TonB-dependent outer membrane receptor Haemin uptake system outer membrane receptor Hemophore HasA Mannosides-regulated TonB-dependent outer membrane receptor MotA/TolQ/ExbB proton channel family protein N-acetylglucosamine-regulated TonB-dependent outer membrane receptor Outer membrane ferripyoverdine receptor Outer membrane lipoprotein omp16 precursor Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Peptidoglycan-associated lipoprotein precursor Predicted b-glucoside-specific TonB-dependent outer membrane receptor Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Putative OMR family iron-siderophore receptor precursor Putative TolA protein Putative TolA protein involved in Tol transport system in Chlamydia Putative Ton-B dependent hemine receptor Putative tonB protein Sialic acid-regulated TonB-dependent outer membrane receptor TPR domain protein, putative component of TonB system TPR repeat containing exported protein Tol biopolymer transport system, TolR protein TolA protein TonB system biopolymer transport component TonB-dependent hemin , ferrichrome receptor TonB-dependent receptor TonB-dependent siderophore receptor Type I secretion outer membrane protein, TolC precursor iron-chelator utilization protein putative TolA function tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins Transport_of_Manganese Manganese ABC transporter, ATP-binding protein SitB Manganese ABC transporter, inner membrane permease protein SitC Manganese ABC transporter, inner membrane permease protein SitD Manganese ABC transporter, periplasmic-binding protein SitA Manganese transport protein MntH Manganese uptake regulation protein MUR Mn-dependent transcriptional regulator MntR Predicted manganese transporter, 11 TMS Transport_of_Molybdenum DNA-binding domain of ModE Molybdate-binding domain of ModE Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) Molybdenum transport ATP-binding protein ModC (TC 3.A.1.8.1) Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) Molybdenum transport system protein ModD Predicted molybdate-responsive regulator YvgK in bacilli Transport_of_Nickel_and_Cobalt ATPase component CbiO of energizing module of cobalt ECF transporter ATPase component NikO of energizing module of nickel ECF transporter Additional component NikL of nickel ECF transporter Additional periplasmic component NikK of nickel ECF transporter Additional substrate-specific component CbiN of cobalt ECF transporter Additional substrate-specific component NikN of nickel ECF transporter HoxN/HupN/NixA family cobalt transporter HoxN/HupN/NixA family nickel/cobalt transporter HupE-UreJ family cobalt transporter HupE-UreJ family metal transporter Nicel/Cobalt-specific TonB-dependent outer membrane receptor Nickel ABC transporter, periplasmic nickel-binding protein NikA (TC 3.A.1.5.3) Nickel ABC transporter, periplasmic nickel-binding protein nikA2 (TC 3.A.1.5.3) Nickel responsive regulator NikR Nickel transport ATP-binding protein NikD (TC 3.A.1.5.3) Nickel transport ATP-binding protein NikE (TC 3.A.1.5.3) Nickel transport ATP-binding protein nikD2 (TC 3.A.1.5.3) Nickel transport ATP-binding protein nikE2 (TC 3.A.1.5.3) Nickel transport system permease protein NikB (TC 3.A.1.5.3) Nickel transport system permease protein NikC (TC 3.A.1.5.3) Nickel transport system permease protein nikB2 (TC 3.A.1.5.3) Nickel transport system permease protein nikC2 (TC 3.A.1.5.3) Nickel transporter UreH Predicted cobalt ABC transporter periplasmic component Predicted cobalt transporter CbtA Predicted cobalt transporter CbtC Predicted cobalt transporter in Mycobacteria Predicted cobalt transporter in sulfate-reducing delta-proteobacteria Substrate-specific component CbiM of cobalt ECF transporter Substrate-specific component NikM of nickel ECF transporter Transmembrane component CbiQ of energizing module of cobalt ECF transporter Transmembrane component NikQ of energizing module of nickel ECF transporter Transport_of_Zinc COG0523: Putative GTPases (G3E family) Candidate Zn-dependent transcriptional regulator, MntR/DtxR family Candidate zinc-binding lipoprotein ZinT Predicted zinc regulator, ArsR family Predicted zinc-binding protein Transcriptional repressor AdcR for Zn(2+)-responsive expression Zinc ABC transporter, ATP-binding protein ZnuC Zinc ABC transporter, inner membrane permease protein ZnuB Zinc ABC transporter, periplasmic-binding protein ZnuA Zinc transporter, ZIP family Zinc uptake regulation protein ZUR Zinc-regulated TonB-dependent outer membrane receptor Zinc-regulated outer membrane porin Zinc-regulated outer membrane receptor Zinc-regulated zinc transporting ATPase ZntA 01 Metabolism of Aromatic Compounds 02 Anaerobic degradation of aromatic compounds Anaerobic_benzoate_metabolism 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (EC 1.1.1.-) 2-ketocyclohexanecarboxyl-CoA hydrolase (EC 4.1.3.36) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) 6-hydroxycylohex-1-ene-1-carbonyl-CoA dehydrogenase 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase Acetyl-CoA acetyltransferase (EC 2.3.1.9) Benzoate-CoA ligase (EC 6.2.1.25) Benzoyl-CoA reductase subunit BadD (EC 1.3.99.15) Benzoyl-CoA reductase subunit BadE (EC 1.3.99.15) Benzoyl-CoA reductase subunit BadF (EC 1.3.99.15) Benzoyl-CoA reductase subunit BadG (EC 1.3.99.15) Cyclohex-1-ene-1-carboxyl-CoA hydratase (EC 4.2.1.17) Cyclohexa-1,5-dienecarbonyl-CoA hydratase (EC 4.2.1.100) Enoyl CoA-hydratase (EC 4.2.1.17) Enoyl-CoA hydratase (EC 4.2.1.-) Glutaryl-CoA dehydrogenase (EC 1.3.99.7) Phosphinothricin acetyltransferase (EC 2.3.1.-) Pimeloyl-CoA dehydrogenase (EC 1.3.1.62) Hydroxyaromatic_decarboxylase_family Hydroxyaromatic non-oxidative decarboxylase protein B (EC 4.1.1.-) Hydroxyaromatic non-oxidative decarboxylase protein C (EC 4.1.1.-) Hydroxyaromatic non-oxidative decarboxylase protein D (EC 4.1.1.-) 02 Metabolism of central aromatic intermediates 4-Hydroxyphenylacetic_acid_catabolic_pathway 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.-) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) 3,4-dihydroxyphenylacetate 2,3-dioxygenase (EC 1.13.11.15) 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3) 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) 5-carboxymethyl-2-hydroxymuconate delta-isomerase (EC 5.3.3.10) 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.2.1.60) 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) Homoprotocatechuate degradative operon repressor Transcriptional activator of 4-hydroxyphenylacetate 3-monooxygenase operon, XylS/AraC family Catechol_branch_of_beta-ketoadipate_pathway 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) 3-oxoadipate enol-lactone hydrolase Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) Catechol 1,2-dioxygenase (EC 1.13.11.1) Catechol 1,2-dioxygenase 1 (EC 1.13.11.1) Muconate cycloisomerase (EC 5.5.1.1) Muconolactone isomerase (EC 5.3.3.4) Muconolactone isomerase (EC 5.3.3.4),putative Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) mandelate racemase/muconate lactonizing enzyme family protein Central_meta-cleavage_pathway_of_aromatic_compound_degradation 1,2-dihydroxynaphthalene dioxygenase 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-) 2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9) 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3,4-dihydroxyphenylacetate 2,3-dioxygenase (EC 1.13.11.15) 4-oxalocrotonate tautomerase (EC 5.3.2.-) 5-carboxymethyl-2-hydroxymuconate delta-isomerase (EC 5.3.3.10) 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.2.1.60) Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol Catechol 2,3-dioxygenase (EC 1.13.11.2) Intradiol ring-cleavage dioxygenase (EC 1.13.11.1) Protocatechuate 4,5-dioxygenase alpha chain (EC 1.13.11.8) Protocatechuate 4,5-dioxygenase beta chain (EC 1.13.11.8) extradiol dioxygenase large subunit putative ring-hydroxylating dioxygenase small subunit Homogentisate_pathway_of_aromatic_compound_degradation 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) Aromatic-amino-acid aminotransferase (EC 2.6.1.57) Fumarylacetoacetase (EC 3.7.1.2) Homogentisate 1,2-dioxygenase (EC 1.13.11.5) Maleylacetoacetate isomerase (EC 5.2.1.2) Possible 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-) Transcriptional regulator, IclR family N-heterocyclic_aromatic_compound_degradation 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16) Protocatechuate_branch_of_beta-ketoadipate_pathway 3-carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) Pca regulon regulatory protein PcaR PhaK-like protein Protocatechuate 3,4-dioxygenase alpha chain (EC 1.13.11.3) Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) dicarboxylic acid transporter PcaT Salicylate_and_gentisate_catabolism 4-hydroxybenzoate transporter AreA (Esterase for aryl ester catabolic pathway) (EC 3.1.1.-) AreB (Aryl-alcohol dehydrogenase) (EC 1.1.1.90) Fumarylacetoacetase (EC 3.7.1.2) Fumarylacetoacetate (FAA) hydrolase (EC 3.7.1.5) Fumarylacetoacetate (FAA) hydrolase (EC 4.1.1.68) Fumarylacetoacetate hydrolase family protein Gentisate 1,2-dioxygenase (EC 1.13.11.4) Maleate cis-trans isomerase (EC 5.2.1.1) Maleylacetoacetate isomerase (EC 5.2.1.2) Putative n-hydroxybenzoate hydroxylase Salicylate hydroxylase (EC 1.14.13.1) putative facilitator of salicylate uptake regulator protein,AreR regulator protein,SalR salicylate esterase 02 Peripheral pathways for catabolism of aromatic compounds Benzoate_catabolism 3-Oxoadipate enol-lactonase (EC 3.1.1.24) Acetyl-CoA C-acyltransferase (EC 2.3.1.16) Benzoate 1,2-dioxygenase (EC 1.14.12.10) Benzoate 1,2-dioxygenase beta subunit (EC 1.14.12.10) Catechol 1,2-dioxygenase (EC 1.13.11.1) Muconate cycloisomerase (EC 5.5.1.1) Muconolactone isomerase (EC 5.3.3.4) Benzoate_degradation 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) 2-chlorobenzoate 1,2-dioxygenase (EC 1.14.12.13) Benzoate 1,2-dioxygenase alpha subunit (EC 1.14.12.10) Benzoate 1,2-dioxygenase beta subunit (EC 1.14.12.10) Benzoate catabolic operon transcription regulator Benzoate transport protein Benzoylformate decarboxylase (EC 4.1.1.7) Ortho-halobenzoate 1,2-dioxygenase alpha-ISP protein OhbB Ortho-halobenzoate 1,2-dioxygenase beta-ISP protein OhbA Ring hydroxylating dioxygenase, alpha subunit (EC 1.14.12.13) benABC operon transcriptional activator BenR benzoate MFS transporter BenK benzoate dioxygenase, ferredoxin reductase component benzoate-specific porin Biphenyl_Degradation 2,3-dihydroxybiphenyl 1,2-dioxygenase 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-) 2-hydroxypenta-2,4-dienoate hydratase 2-keto-4-pentenoate hydratase (EC 4.2.1.-) 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) Acetaldehyde dehydrogenase (EC 1.2.1.10) Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol Biphenyl dioxygenase alpha subunit (EC 1.14.12.18) Biphenyl dioxygenase beta subunit (EC 1.14.12.18) Biphenyl dioxygenase system ferredoxin component Biphenyl dioxygenase system ferredoxin--NAD( ) reductase component (EC 1.18.1.3) Biphenyl-2,3-diol 1,2-dioxygenase (EC 1.13.11.39) Dihydrodiol dehydrogenase (EC 1.3.1.56) Large subunit naph/bph dioxygenase Small subunit naph/bph dioxygenase biphenyl-2,3-diol 1,2-dioxygenase III-related protein biphenyl-2,3-diol 1,2-dioxygenase III-related protein VCA0463 VCA0328 VCA0341 Chloroaromatic_degradation_pathway 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) Chlorocatechol 1,2-dioxygenase Chlorobenzoate_degradation 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) 2-chlorobenzoate 1,2-dioxygenase alpha subunit (EC 1.14.12.13) 2-chlorobenzoate 1,2-dioxygenase beta subunit (EC 1.14.12.13) 2-chlorobenzoate 1,2-dioxygenase reductase component Catechol 1,2-dioxygenase (EC 1.13.11.1) Muconate cycloisomerase (EC 5.5.1.1) Putative benzaldehyde dehydrogenase oxidoreductase protein (EC 1.2.1.28) Naphtalene_and_antracene_degradation 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase 1,2-dihydroxybenzyl pyruvate aldolase 1,2-dihydroxynaphthalene dioxygenase 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase (EC 1.3.1.-) 2-hydroxybenzalpyruvate aldolase 2-hydroxychromene-2-carboxylate isomerase Dihydrodiol dehydrogenase (EC 1.3.1.56) Naphthalene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component (EC 1.18.1.3) Salicylaldehyde dehydrogenase (EC 1.2.1.65) dihydroxy naphthalene/biphenyl dioxygenase ferredoxin subunit aromatic oxygenase naphthalene dioxygenase Fe-S protein large subunit naphthalene dioxygenase Fe-S protein small subunit naphthalene dioxygenase ferredoxin naphthalene dioxygenase reductase trans-o-hydroxybenzylidenepyruvate hydratase-aldolase Phenol_hydroxylase Phenol hydroxylase, FAD- and [2Fe-2S]-containing reductase component DmpP Phenol hydroxylase, P1 oxygenase component DmpL (EC 1.14.13.7) Phenol hydroxylase, P2 regulatory component DmpM (EC 1.14.13.7) Phenol hydroxylase, P3 oxygenase component DmpN (EC 1.14.13.7) Phenol hydroxylase, P4 oxygenase component DmpO (EC 1.14.13.7) Phenol hydroxylase, assembly protein DmpK Positive regulator of phenol hydroxylase Phenylpropanoid_compound_degradation 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase (EC 1.3.1.-) 3-hydroxyphenylpropionic acid transporter 4-hydroxybenzoate transporter 4-hydroxycinnamoyl CoA hydratase/lyase (Enoyl-CoA hydratase/lyase) (EC 4.2.1.17) Acyl coenzyme A dehydrogenase (EC 1.3.99.13) Chlorogenate esterase Feruloyl-CoA synthetase Lignostilbene-alpha,beta-dioxygenase and related enzymes Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Probable FERULIC acid hydratase protein Probable FERULOYL-CoA synthetase protein Probable VANILLIN dehydrogenase oxidoreductase protein (EC 1.-.-.-) Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) Protein involved in meta-pathway of phenol degradation Putative 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase oxidoreductase protein (EC 1.1.1.50) Putative benzaldehyde dehydrogenase oxidoreductase protein (EC 1.2.1.28) Putative hydroxycinnamate transporter Putative phthalate 4,5-dioxygenase oxygenase subunit (OhpA2) Putative phthalate 4,5-dioxygenase reductase subunit (OhpA1) Transcriptional regulator for ferulate or vanillate catabolism Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) Vanillate O-demethylase oxygenase subunit (EC 1.14.13.82) Vanillin dehydrogenase (Hydroxybenzaldehyde dehydrogenase) (EC 1.2.1.28) hydroxycinnamate specific porine lignostilbene-alpha,beta-dioxygenase putative 3-hydroxyphenylpropionic acid porine putative porin for vanillate trafficking (VanP) vannilate transporter VanK Quinate_degradation 3-dehydroquinate dehydratase I (EC 4.2.1.10) 3-dehydroquinate dehydratase II (EC 4.2.1.10) 3-dehydroshikimate dehydratase Quinate/shikimate dehydrogenase [Pyrroloquinoline-quinone] (EC 1.1.99.25) Shikimate 5-dehydrogenase (EC 1.1.1.25) Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282) Salicylate_ester_degradation AreA (Esterase for aryl ester catabolic pathway) (EC 3.1.1.-) AreB (Aryl-alcohol dehydrogenase) (EC 1.1.1.90) Salicylate hydroxylase (EC 1.14.13.1) putative facilitator of salicylate uptake regulator protein,AreR regulator protein,SalR salicylate esterase Toluene_degradation Toluate 1,2-dioxygenase alpha subunit Toluate 1,2-dioxygenase beta subunit Toluate 1,2-dioxygenase electron transfer component Toluene-4-monooxygenase, subunit TmoD toluenesulfonate zinc-independent alcohol dehydrogenase n-Phenylalkanoic_acid_degradation 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) Enoyl-CoA hydratase (EC 4.2.1.17) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Putative 3-hydroxyacyl-coa dehydrogenase enoyl-CoA hydratase, R-specific p-Hydroxybenzoate_degradation 4-hydroxybenzoate transporter P-hydroxybenzoate hydroxylase (EC 1.14.13.2) 02 Aromatic_Amin_Catabolism 3,4-dihydroxyphenylacetate 2,3-dioxygenase (EC 1.13.11.15) 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3) 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ Monoamine oxidase (1.4.3.4) Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) Phenylacetaldehyde dehydrogenase (EC 1.2.1.39) Benzoate_transport_and_degradation_cluster 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) 3-hydroxyacyl-CoA dehydrogenase (PaaH) (EC 1.1.1.157) 4-hydroxybenzoyl-CoA reductase, beta subunit (EC 1.3.99.20) 4-hydroxybenzoyl-CoA reductase, gamma subunit (EC 1.3.99.20) 4-oxalocrotonate decarboxylase (EC 4.1.1.77) Benzoate transport related protein Benzoate transport, ATP binding protein Benzoate transport, ATPase component Benzoate transport, extracellular ligand-binding receptor Benzoate transport, inner membrane transport component Benzoate transport, inner-membrane translocator Benzoate transport, inner-membrane translocator precursor Benzoate-CoA ligase (EC 6.2.1.25) Benzoyl-CoA oxygenase component A Benzoyl-CoA oxygenase component B Beta-ketoadipyl CoA thiolase (EC 2.3.1.9) Hydroxybenzoyl-CoA reductase subunit Methylglutaconyl-CoA hydratase (EC 4.2.1.18) P-hydroxylaminobenzoate lyase Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase Putative Acyl-CoA thiolase Regulatory protein of benzoate catabolism Shikimate kinase I (EC 2.7.1.71) Shikimate kinase II (EC 2.7.1.71) benzoate degradation ring-cleavage hydrolase benzoyl-CoA-dihydrodiol lyase (BoxC) hydroxybenzoate permease Cresol_degradation 4-cresol dehydrogenase [hydroxylating] cytochrome c subunit precursor 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit (EC 1.17.99.1) Gentisare_degradation 4-hydroxybenzoate transporter Fumarylacetoacetate hydrolase family protein Gentisate 1,2-dioxygenase (EC 1.13.11.4) Maleylacetoacetate isomerase (EC 5.2.1.2) Putative n-hydroxybenzoate hydroxylase putative 4-hydroxybenzoyl-CoA thioesterase Phenylacetyl-CoA_catabolic_pathway_(core) 3-hydroxyacyl-CoA dehydrogenase PaaC (EC 1.1.1.-) Acetate permease ActP (cation/acetate symporter) PaaL Phenylacetaldehyde dehydrogenase (EC 1.2.1.39) Phenylacetate degradation enoyl-CoA hydratase PaaA (EC 4.2.1.17) Phenylacetate degradation enoyl-CoA hydratase PaaB (EC 4.2.1.17) Phenylacetate-CoA oxygenase, PaaG subunit Phenylacetate-CoA oxygenase, PaaH subunit Phenylacetate-CoA oxygenase, PaaI subunit Phenylacetate-CoA oxygenase, PaaJ subunit Phenylacetate-CoA oxygenase/reductase, PaaK subunit Phenylacetate-coenzyme A ligase (EC 6.2.1.30) PaaF Phenylacetic acid degradation operon negative regulatory protein PaaX Phenylacetic acid degradation protein PaaD, thioesterase Phenylacetic acid degradation protein PaaE, ketothiolase Phenylacetic acid degradation protein PaaN, ring-opening aldehyde dehydrogenase (EC 1.2.1.3) Phenylacetic acid degradation protein PaaN2, ring-opening aldehyde dehydrogenase (EC 1.2.1.3) Phenylacetic acid degradation protein PaaY Phenylacetic acid-specific porin PaaM Putative membrane protein, clustering with ActP PaaL Toluene_4-monooxygenase_(T4MO) Toluene-4-monooxygenase, subunit TmoA Toluene-4-monooxygenase, subunit TmoA alpha Toluene-4-monooxygenase, subunit TmoA beta Toluene-4-monooxygenase, subunit TmoB Toluene-4-monooxygenase, subunit TmoC Toluene-4-monooxygenase, subunit TmoD Toluene-4-monooxygenase, subunit TmoE Toluene-4-monooxygenase, subunit TmoF carbazol_degradation_cluster 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-) 2-hydroxypent-2,4-dienoate hydratase (EC 4.2.-.-) 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) Acetaldehyde dehydrogenase (acylating) Catalitic subunit of carbazole 1,9a-dioxygenase Ferredoxin component of carbazole 1,9a-dioxygenase Ferredoxin reductase component of carbazole 1,9a-dioxygenase Terminal dioxygenase component of carbazole 1,9a-dioxygenase p-cymene_degradation 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase(CmtB) (EC 1.1.1.100) 2,3-dihydroxy-p-cumate-3,4-dioxygenase (CmtC) 2-hydroxypenta-2,4-dienoate hydratase (CmtF) (EC 4.2.1.-) HCOMODA decarboxylase HOMODA hydrolase (CmtE) (EC 3.7.1.-) P-cymene methyl hydroxylase P-cymene monooxygenase, reductase subunit(CymAb) (EC 1.17.1.-) p-cumate dioxygenase ferredoxin p-cumate dioxygenase ferredoxin reductase subunit (CmtAa) p-cumate dioxygenase large subunit (CmtAb) p-cumate dioxygenase small subunit (CmtAc) p-cumic alcohol dehydrogenase (CymB) p-cumic aldehyde dehydrogenase (CymC) [EC:1.2.1.3] p-cymene degradation operon transcriptional regulator p-cymene monooxygenase, hydroxylase subunit(CymAa) 01 Miscellaneous 02 Plant-Prokaryote DOE project At2g33980_At1g28960 FIG003620: Proteophosphoglycan precursor (Fragment) FIG017823: ATPase, MoxR family Hypothetical nudix hydrolase YeaB tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25) At3g21300 Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7) RNA methyltransferase, TrmA family Transcription regulator [contains diacylglycerol kinase catalytic domain] COG2363 COG2363 Cysteine desulfurase (EC 2.8.1.7) Cysteine desulfurase (EC 2.8.1.7), IscS subfamily Cysteine desulfurase (EC 2.8.1.7), NifS subfamily Cysteine desulfurase (EC 2.8.1.7), SufS subfamily Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA Cysteine desulfurase CsdA-CsdE, sulfur acceptor protein CsdE Hydroxyethylthiazole kinase (EC 2.7.1.50) Hydroxymethylpyrimidine ABC transporter, substrate-binding component Phosphomethylpyrimidine kinase (EC 2.7.4.7) Predicted thiazole transporter ThiU Predicted thiazole transporter ThiW Sulfur acceptor protein SufE for iron-sulfur cluster assembly Sulfur carrier protein ThiS ThiJ/PfpI family protein Thiamin biosynthesis protein ThiC Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Thiaminase II (EC 3.5.99.2) Thiamine biosynthesis protein thiI Thiazole biosynthesis protein ThiG Conserved_gene_cluster_possibly_involved_in_RNA_metabolism Cysteinyl-tRNA synthetase (EC 6.1.1.16) DegV family protein in cluster with TrmH family tRNA/rRNA methyltransferase YacO Hypothetical protein DUF901, similar to C-terminal domain of ribosome protection-type Tc-resistance proteins Hypothetical protein, Slr0957 homolog Hypothetical protein, Spy1939 homolog Putative anti-sigma factor antagonist RNA polymerase sporulation specific sigma factor SigH Serine acetyltransferase (EC 2.3.1.30) Small protein similar to cysteinyl-tRNA synthetase TrmH family tRNA/rRNA methyltransferase YacO (EC 2.1.1.-) Iojap Adenylate cyclase (EC 4.6.1.1) Biotin-protein ligase (EC 6.3.4.15) COG0536: GTP-binding protein Obg FIG004454: RNA binding protein FIGfam135315: Iojap-related protein GTP-binding protein YqeH, possibly involved in replication initiation Gamma-glutamyl phosphate reductase (EC 1.2.1.41) Glutamate 5-kinase (EC 2.7.2.11) Hydrolase (HAD superfamily), YqeK Inorganic pyrophosphatase (EC 3.6.1.1) LSU m3Psi1915 methyltransferase RlmH LSU ribosomal protein L21p LSU ribosomal protein L27p N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) Nicotinamidase (EC 3.5.1.19) Nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase, NadM family (EC 2.7.7.1) Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18), eukaryotic PNAT family Orotate phosphoribosyltransferase (EC 2.4.2.10) Phosphatidate cytidylyltransferase (EC 2.7.7.41) tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) Synechocystis_experimental Chlorophyllase (EC 3.1.1.14) Esterase D (EC 3.1.1.1) Esterase/lipase, sll0644 homolog Esterase/lipase/thioesterase family, pmt2269 homolog Esterase/lipase/thioesterase, slr0421 homolog Hydrolase alpha/beta fold family, slr0264 homolog Hypothetical protein, slr1506/slr1944 homolog Lipase (EC 3.1.1.3) family protein, sll1969 homolog Lysophospholipase L2 (EC 3.1.1.5) Menaquinone biosynthesis related protein, putative DHNA-CoA thioesterase Phospholipase/carboxylesterase family protein, sll1284 homolog Possible alpha/beta hydrolase superfamily, ct0524 homolog Possible alpha/beta hydrolase superfamily, sll0553 homolog Possible alpha/beta hydrolase superfamily, sll1129 homolog Possible alpha/beta hydrolase superfamily, slr1235 homolog Possible alpha/beta hydrolase superfamily, slr1827 homolog Possible alpha/beta hydrolase superfamily, slr1916 homolog Possible alpha/beta hydrolase superfamily, slr1917 homolog Possible alpha/beta hydrolase superfamily, tll2163 homolog Serine peptidase (Alpha/beta hydrolase superfamily) fused to N- terminal uncharacterized domain specific to cyanobacteria Similar to non-heme chloroperoxidase Similar to non-heme chloroperoxidase, sll5080 homolog hypothetical protein slr1932 prolyl oligopeptidase family protein 02 Archease Archease Archease2 Archease SSO0251 family tRNA and rRNA cytosine-C5-methylase Type 1 tRNA m(1)G methyltransferase; COG2419: Uncharacterized ACR tRNA/RNA cytosine-C5-methylase (EC 2.1.1.-) Broadly_distributed_proteins_not_in_subsystems DUF1022 domain-containing protein Putative oxidoreductase YncB UPF0234 protein YajQ UPF0265 protein YeeX UPF0434 protein YcaR YbbL ABC transporter ATP-binding protein YbbM seven transmembrane helix protein YciL protein YpfJ protein, zinc metalloprotease superfamily YrbA protein Luciferases Autoinducer synthesis protein LuxI LuxA, luciferase alpha chain (EC 1.14.14.3) LuxB, luciferase beta chain (EC 1.14.14.3) LuxC, acyl-CoA reductase (EC 1.2.1.50) LuxD. acyl transferase (EC 2.3.1.-) LuxE, long-chain-fatty-acid ligase (EC 6.2.1.19) LuxG, NAD(P)H-dependent FMN reductase (EC 1.5.1.29) Transcriptional activator protein LuxR Magnetosome_Biomineralization_and_Function Glycine-rich cell wall structural protein 1.0 precursor Magnetosome protein MamC Magnetosome protein MamF Magnetosome protein MamS Muconate_lactonizing_enzyme_family L-alanine-DL-glutamate epimerase Muconate cycloisomerase (EC 5.5.1.1) N-acylamino acid racemase N-succinyl arginine/lysine racemase O-succinylbenzoate-CoA synthase (EC 4.2.1.-) YaaA UPF0246 protein YaaA YbbK Putative activity regulator of membrane protease YbbK Putative membrane-bound ClpP-class protease associated with aq_911 Putative stomatin/prohibitin-family membrane protease subunit YbbK Putative stomatin/prohibitin-family membrane protease subunit aq_911 ZZ_gjo_need_homes AMP/CMP kinase AK6 Cephalosporin hydroxylase Cob(I)alamin adenosyltransferase fragment GTP-binding protein RBG1 GTP-binding protein, gtp1/obg family Hydroxylamine oxidoreductase precursor (EC 1.7.3.4) Lipid A export ATP-binding/permease protein MsbA LysR family transcriptional regulator clustered with dicarboxylate transport MFS superfamily export protein YceL Microcompartment protein protein similar to PduA/PduJ Mitochondrial processing peptidase-like protein (EC 3.4.24.64) Na+/H+ antiporter Na+/H+ antiporter NhaB Peptidyl-tRNA hydrolase, archaeal type (EC 3.1.1.29) Phage-encoded chromosome degrading nuclease YokF Phosphatidyl-N-methylethanolamine N-methyltransferase (EC 2.1.1.71) Phosphatidylcholine synthase (EC 2.7.8.24) Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated Pole remodelling regulatory diguanylate cyclase Proposed peptidoglycan lipid II flippase MurJ Protein of unknown function DUF81 Protein of unknown function DUF81, type 2 Protein of unknown function YceH Protein secretion chaperonin CsaA Proton/aspartate symport protein Proton/glutamate symport protein Putative GTP-binding protien TM0445 Putative heat shock protein YegD Putative membrane protein YfcA Putative permease PerM (= YfgO) Putative permease often clustered with de novo purine synthesis Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) Quinone oxidoreductase (EC 1.6.5.5) RNase L inhibitor Sodium/glutamate symport protein Transcription accessory protein (S1 RNA-binding domain) Tyrosine-specific transport protein Uncharacterized ATP-dependent helicase MJ0294 Virulence factor MviM 01 Motility and Chemotaxis 02 Flagellar motility in Prokaryota Additional_flagellar_genes_in_Vibrionales Flagellar protein FlgO Flagellar protein FlgP Flagellar protein FlgT Archaeal_Flagellum Flagella-related protein FlaC Flagella-related protein FlaD Flagella-related protein FlaE Flagella-related protein FlaF Flagella-related protein FlaG Flagella-related protein FlaH Flagella-related protein FlaI Flagella-related protein FlaJ Flagellin FlaA1 Flagellin FlaA2 Flagellin FlaB Flagellin FlaB1 Flagellin FlaB2 Flagellin FlaB3 Flagellar_motility Chemotaxis protein CheV (EC 2.7.3.-) Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY Flagellar L-ring protein FlgH Flagellar basal-body rod modification protein FlgD Flagellar biosynthesis protein FlhA Flagellar biosynthesis protein FlhB Flagellar biosynthesis protein FlhF Flagellar biosynthesis protein FliR Flagellar motor rotation protein MotA Flagellar motor rotation protein MotB Flagellar motor switch protein FliM Flagellar motor switch protein FliN Flagellar synthesis regulator FleN Flagellin Flagellum-specific ATP synthase FliI Motility accessory factor Motility integral membrane protein Predicted signal transduction protein Putative lipoprotein required for motility RNA polymerase sigma factor for flagellar operon RNA polymerase sigma-54 factor RpoN Rrf2 family transcriptional regulator Signal transduction histidine kinase CheA (EC 2.7.3.-) Signal transduction protein CetA, mediates an energy taxis response Signal transduction protein CetB, mediates an energy taxis response Flagellum Flagellar L-ring protein FlgH Flagellar M-ring protein FliF Flagellar P-ring protein FlgI Flagellar assembly protein FliH Flagellar basal-body P-ring formation protein FlgA Flagellar basal-body rod modification protein FlgD Flagellar basal-body rod protein FlgB Flagellar basal-body rod protein FlgC Flagellar basal-body rod protein FlgF Flagellar basal-body rod protein FlgG Flagellar biosynthesis protein FlgN Flagellar biosynthesis protein FlhA Flagellar biosynthesis protein FlhB Flagellar biosynthesis protein FlhF Flagellar biosynthesis protein FliC Flagellar biosynthesis protein FliL Flagellar biosynthesis protein FliO Flagellar biosynthesis protein FliP Flagellar biosynthesis protein FliQ Flagellar biosynthesis protein FliR Flagellar biosynthesis protein FliS Flagellar biosynthesis protein FliT Flagellar biosynthesis protein FliZ Flagellar hook protein FlgE Flagellar hook-associated protein 3 Flagellar hook-associated protein FlgK Flagellar hook-associated protein FlgL Flagellar hook-associated protein FliD Flagellar hook-basal body complex protein FliE Flagellar hook-length control protein FliK Flagellar motor rotation protein MotA Flagellar motor rotation protein MotB Flagellar motor switch protein FliG Flagellar motor switch protein FliM Flagellar motor switch protein FliN Flagellar protein FlbB Flagellar protein FlbD Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) Flagellar protein FlhE Flagellar protein FliJ Flagellar regulatory protein FleQ Flagellar sensor histidine kinase FleS Flagellar synthesis regulator FleN Flagellar trans-acting factor FliX Flagellar transcriptional activator FlhC Flagellar transcriptional activator FlhD Flagellin protein FlaA Flagellin protein FlaB Flagellin protein FlaC Flagellin protein FlaD Flagellin protein FlaE Flagellin protein FlaF Flagellin protein FlaG Flagellum-specific ATP synthase FliI Negative regulator of flagellin synthesis Negative regulator of flagellin synthesis FlgM RNA polymerase sigma factor RpoD RNA polymerase sigma factor for flagellar operon RNA polymerase sigma-54 factor RpoN Flagellum_in_Campylobacter Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) Flagellar basal-body rod protein FlgB Flagellar basal-body rod protein FlgC Flagellar hook subunit protein Flagellar hook-basal body complex protein FliE Flagellin protein FlaA Flagellin protein FlaB 02 Social motility and nonflagellar swimming in bacteria Control_of_Swarming_in_Vibrio_and_Shewanella_species Aminotransferase ScrA Extracellular solute binding protein ScrB Sensory box/GGDEF family protein ScrC (involved in swarmer cell regulation) Transcriptional regulator LuxZ Rhamnolipids_in_Pseudomonas (R)-3-hydroxydecanoyl-ACP:CoA transacylase PhaG (3-hydroxyacyl-CoA-acyl carrier protein transferase) (EC 2.4.1.-) N-acyl-L-homoserine lactone synthetase RhlL Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase RhlG (EC 1.1.1.100) RhlA, 3-(3-hydroxyalkanoyloxy)alkanoic acids (HAAs) synthase RhlB, TDP-rhamnosyltransferase 1 (EC 2.4.1.-) RhlC, TDP-rhamnosyltransferase 2 (EC 2.4.1.-) Transcriptional regulator RhlR 02 Bacterial_Chemotaxis Aerotaxis sensor receptor protein Chemotaxis protein CheC -- inhibitor of MCP methylation Chemotaxis protein CheD Chemotaxis protein CheV (EC 2.7.3.-) Chemotaxis protein CheX Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY Chemotaxis response - phosphatase CheZ Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) Flagellar motor switch protein FliG Flagellar motor switch protein FliM Flagellar motor switch protein FliN Galactose/methyl galactoside ABC transport system, D-galactose-binding periplasmic protein MglB (TC 3.A.1.2.3) Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) Methyl-accepting chemotaxis protein II (aspartate chemoreceptor protein) Methyl-accepting chemotaxis protein III (ribose and galactose chemoreceptor protein) Methyl-accepting chemotaxis protein IV (dipeptide chemoreceptor protein) Positive regulator of CheA protein activity (CheW) Ribose ABC transporter, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) Signal transduction histidine kinase CheA (EC 2.7.3.-) 01 Nitrogen Metabolism Allantoin_Utilization 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) Allantoate amidohydrolase (EC 3.5.3.9) Allantoicase (EC 3.5.3.4) Allantoin permease Allantoinase (EC 3.5.2.5) DNA-binding transcriptional activator of the allD operon Glycerate kinase (EC 2.7.1.31) Glyoxylate carboligase (EC 4.1.1.47) Negative regulator of allantoin and glyoxylate utilization operons Ureidoglycolate dehydrogenase (EC 1.1.1.154) Ureidoglycolate hydrolase (EC 3.5.3.19) Amidase_clustered_with_urea_and_nitrile_hydratase_functions Amidase clustered with urea ABC transporter and nitrile hydratase functions Ammonia_assimilation Ammonium transporter Ammonium transporter family Ferredoxin-dependent glutamate synthase (EC 1.4.7.1) Global nitrogen regulatory protein, CRP family of transcriptional regulators Glutamate synthase [NADPH] large chain (EC 1.4.1.13) Glutamate synthase [NADPH] putative GlxC chain (EC 1.4.1.13) Glutamate synthase [NADPH] small chain (EC 1.4.1.13) Glutamate synthase, alpha subunit domain protein Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) Glutamine amidotransferase protein GlxB (EC 2.4.2.-) Glutamine amidotransferase, class-II Glutamine synthetase inactivating factor IF17 Glutamine synthetase inactivating factor IF7 Glutamine synthetase type I (EC 6.3.1.2) Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) Glutamine synthetase type III, GlnN (EC 6.3.1.2) Glutamine synthetase, clostridia type (EC 6.3.1.2) Nitrogen regulation protein NR(I) Nitrogen regulation protein NR(II) (EC 2.7.3.-) Nitrogen regulatory protein P-II Nitrogen regulatory protein P-II, glnK Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) [Protein-PII] uridylyltransferase (EC 2.7.7.59) ammonium/methylammonium permease Cyanate_hydrolysis Carbonic anhydrase (EC 4.2.1.1) Cyanate ABC transporter, ATP-binding protein Cyanate ABC transporter, permease protein Cyanate ABC transporter, substrate binding protein Cyanate hydratase (EC 4.2.1.104) Cyanate transport protein CynX Cyn operon transcriptional activator Transcriptional activator similar to cyn operon regulator Denitrification Copper-containing nitrite reductase (EC 1.7.2.1) Cytochrome cd1 nitrite reductase (EC:1.7.2.1) Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) Nitric oxide -responding transcriptional regulator NnrR (Crp/Fnr family) Nitric oxide reductase activation protein NorD Nitric oxide reductase activation protein NorE Nitric oxide reductase activation protein NorQ Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent Nitric-oxide reductase subunit B (EC 1.7.99.7) Nitric-oxide reductase subunit C (EC 1.7.99.7) Nitrite reductase accessory protein NirV Nitrous oxide reductase maturation periplasmic protein NosX Nitrous oxide reductase maturation protein NosD Nitrous oxide reductase maturation protein NosF (ATPase) Nitrous oxide reductase maturation protein NosR Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL Nitrous oxide reductase maturation transmembrane protein NosY Nitrous-oxide reductase (EC 1.7.99.6) NnrS protein involved in response to NO NnrT family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor) NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor) Dissimilatory_nitrite_reductase Cytochrome c551 NirM Cytochrome c55X precursor NirC Cytochrome cd1 nitrite reductase (EC:1.7.2.1) Heme d1 biosynthesis protein NirD Heme d1 biosynthesis protein NirF Heme d1 biosynthesis protein NirG Heme d1 biosynthesis protein NirH Heme d1 biosynthesis protein NirJ Heme d1 biosynthesis protein NirL Nitrite reductase associated c-type cytochorome NirN Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Nitrate_and_nitrite_ammonification Assimilatory nitrate reductase large subunit (EC:1.7.99.4) Cytochrome c nitrite reductase, small subunit NrfH Cytochrome c-type heme lyase subunit nrfE, nitrite reductase complex assembly Cytochrome c-type heme lyase subunit nrfF, nitrite reductase complex assembly Cytochrome c-type heme lyase subunit nrfG, nitrite reductase complex assembly Cytochrome c-type protein NapC Cytochrome c-type protein NrfB precursor Cytochrome c552 precursor (EC 1.7.2.2) Ferredoxin--nitrite reductase (EC 1.7.7.1) Ferredoxin-type protein NapF (periplasmic nitrate reductase) Ferredoxin-type protein NapG (periplasmic nitrate reductase) Nitrate ABC transporter, ATP-binding protein Nitrate ABC transporter, nitrate-binding protein Nitrate ABC transporter, permease protein Nitrate reductase cytochrome c550-type subunit Nitrate/nitrite response regulator protein Nitrate/nitrite sensor protein (EC 2.7.3.-) Nitrate/nitrite transporter Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4) Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) Nitrite reductase probable [NAD(P)H] subunit (EC 1.7.1.4) Nitrite reductase probable electron transfer 4Fe-S subunit (EC 1.7.1.4) Nitrite transporter NirC Nitrite transporter from formate/nitrite family NrfC protein NrfD protein Periplasmic nitrate reductase component NapD Periplasmic nitrate reductase component NapE Periplasmic nitrate reductase component NapL Periplasmic nitrate reductase precursor (EC 1.7.99.4) Polyferredoxin NapH (periplasmic nitrate reductase) Putative thiol:disulfide oxidoreductase, nitrite reductase complex assembly Respiratory nitrate reductase alpha chain (EC 1.7.99.4) Respiratory nitrate reductase beta chain (EC 1.7.99.4) Respiratory nitrate reductase delta chain (EC 1.7.99.4) Respiratory nitrate reductase gamma chain (EC 1.7.99.4) Respiratory nitrate reductase subunit, conjectural (EC 1.7.99.4) Response regulator NasT Nitric_oxide_synthase Manganese superoxide dismutase (EC 1.15.1.1) Nitric oxide synthase oxygenase (EC 1.-.-.-) putative cytochrome P450 hydroxylase Nitrogen_fixation 4Fe-4S ferredoxin, nitrogenase-associated AnfO protein, required for Mo- and V-independent nitrogenase AnfR protein, required for Mo- and V-independent nitrogenase Cysteine desulfurase (EC 2.8.1.7), NifS subfamily Homocitrate synthase (EC 2.3.3.14) Homocitrate synthase alpha subunit (EC 2.3.3.14) Homocitrate synthase omega subunit (EC 2.3.3.14) Iron-sulfur cluster assembly scaffold protein NifU LRV (FeS)4 cluster domain protein clustered with nitrogenase cofactor synthesis NifB-domain protein, type 2 NifM protein NifT protein NifX-associated protein NifY protein NifZ protein Nitrogenase (iron-iron) alpha chain (EC 1.18.6.1) Nitrogenase (iron-iron) beta chain (EC 1.18.6.1) Nitrogenase (iron-iron) delta chain (EC 1.18.6.1) Nitrogenase (iron-iron) reductase and maturation protein AnfH Nitrogenase (iron-iron) transcriptional regulator Nitrogenase (molybdenum-iron) alpha chain (EC 1.18.6.1) Nitrogenase (molybdenum-iron) beta chain (EC 1.18.6.1) Nitrogenase (molybdenum-iron) reductase and maturation protein NifH Nitrogenase (molybdenum-iron)-specific transcriptional regulator NifA Nitrogenase (vanadium-iron) alpha chain (EC 1.18.6.1) Nitrogenase (vanadium-iron) beta chain (EC 1.18.6.1) Nitrogenase (vanadium-iron) delta chain (EC 1.18.6.1) Nitrogenase (vanadium-iron) reductase and maturation protein VnfH Nitrogenase (vanadium-iron) transcriptional regulator VnfA Nitrogenase FeMo-cofactor carrier protein NifX Nitrogenase FeMo-cofactor scaffold and assembly protein NifE Nitrogenase FeMo-cofactor scaffold and assembly protein NifN Nitrogenase FeMo-cofactor synthesis FeS core scaffold and assembly protein NifB Nitrogenase FeMo-cofactor synthesis molybdenum delivery protein NifQ Nitrogenase cofactor carrier protein NafY Nitrogenase stabilizing/protective protein NifW Nitrogenase vanadium-cofactor synthesis protein VnfE Nitrogenase vanadium-cofactor synthesis protein VnfN Nitrogenase vanadium-cofactor synthesis protein VnfX Nitrogenase vanadium-cofactor synthesis protein VnfY Nitrogenase-associated protein NifO Transcriptional repressor of nif and glnA operons probable iron binding protein from the HesB_IscA_SufA family in Nif operon Nitrosative_stress Anaerobic nitric oxide reductase flavorubredoxin Ferredoxin 3 fused to uncharacterized domain Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR Hcp transcriptional regulator HcpR (Crp/Fnr family) Hydroxylamine reductase (EC 1.7.-.-) NADH oxidoreductase hcr (EC 1.-.-.-) Nitric oxide reductase FlRd-NAD(+) reductase (EC 1.18.1.-) Nitric oxide-dependent regulator DnrN or NorA Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent Nitrite-sensitive transcriptional repressor NsrR NnrS protein involved in response to NO 01 Nucleosides and Nucleotides 02 Detoxification Housecleaning_nucleoside_triphosphate_pyrophosphatases 5'-nucleotidase YjjG (EC 3.1.3.5) 5-nucleotidase SurE (EC 3.1.3.5) Cof protein, HD superfamily hydrolase Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) Dimeric dUTPase (EC 3.6.1.23) Inosine/xanthosine triphosphatase (EC 3.6.1.-) Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) Nucleotidase YfbR, HD superfamily Nucleoside_triphosphate_pyrophosphohydrolase_MazG MazG protein domain MazG-related protein Nucleoside triphosphate pyrophosphohydrolase MazG Nudix_proteins_(nucleoside_triphosphate_hydrolases) 5-methyl-dCTP pyrophosphohydrolase (EC 3.6.1.-) ADP compounds hydrolase NudE (EC 3.6.1.-) ADP-ribose pyrophosphatase (EC 3.6.1.13) ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) GDP-mannose mannosyl hydrolase (EC 3.6.1.-) GDP-mannose pyrophosphatase YffH Hypothetical nudix hydrolase YeaB Low G+C gram positive nudix hydrolase YtkD (EC 3.6.-.-) Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) NADH pyrophosphatase (EC 3.6.1.22) Nudix dNTPase DR0004 (EC 3.6.1.-) Nudix dNTPase DR0092 (EC 3.6.1.-) Nudix dNTPase DR0149 (EC 3.6.1.-) Nudix dNTPase DR0261 (EC 3.6.1.-) Nudix dNTPase DR0274 (EC 3.6.1.-) Nudix dNTPase DR0329 (EC 3.6.1.-) Nudix dNTPase DR0550 (EC 3.6.1.-) Nudix dNTPase DR0784 (EC 3.6.1.-) Nudix dNTPase DR1025 (EC 3.6.1.-) Nudix dNTPase DR1776 (EC 3.6.1.-) Nudix dNTPase DR2356 (EC 3.6.1.-) Nudix family (d)NDPase DR0975 Nudix hydrolase family protein PA3470 Nudix hydrolase family protein YffH Nudix-like NDP and NTP phosphohydrolase YmfB Putative Nudix hydrolase YfcD (EC 3.6.-.-) Pyrimidine deoxynucleoside triphosphate (dYTP) pyrophosphohydrolase YfoO Thiamin-phosphate pyrophosphorylase-like protein Uridine diphosphate glucose pyrophosphatase (EC 3.6.1.45) dATP pyrophosphohydrolase NudB (EC 3.6.1.-) 02 Purines De_Novo_Purine_Biosynthesis Adenylosuccinate lyase (EC 4.3.2.2) Amidophosphoribosyltransferase (EC 2.4.2.14) IMP cyclohydrolase (EC 3.5.4.10) IMP cyclohydrolase (EC 3.5.4.10) [alternate form] Phosphoribosylamine--glycine ligase (EC 6.3.4.13) Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) Phosphoribosylaminoimidazolecarboxamide formyltransferase [alternate form] Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) Possible subunit variant of phosphoribosylaminoimidazolecarboxamide formyltransferase [alternate form] Possible third subunit-variant of phosphoribosylaminoimidazolecarboxamide formyltransferase [alternate form] PurR: transcription regulator associated with purine metabolism Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) YabJ, a purine regulatory protein and member of the highly conserved YjgF family Purine_Utilization Cytosine/purine/uracil/thiamine/allantoin permease family protein Guanine deaminase (EC 3.5.4.3) Guanine-hypoxanthine permease Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit YagS Uracil-xanthine permease Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Xanthine dehydrogenase iron-sulfur subunit (EC 1.17.1.4) Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4) Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A (1.17.1.4) Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4) Xanthine oxidase (EC 1.17.3.2) Xanthine permease Xanthine transporter,putative Xanthine/uracil transporter Xanthine/uracil/thiamine/ascorbate permease family protein XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase) Purine_conversions 2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16) 5'-nucleotidase (EC 3.1.3.5) 5'-nucleotidase family protein in cluster with NagD-like phosphatase AMP nucleosidase (EC 3.2.2.4) Adenine deaminase (EC 3.5.4.2) Adenine phosphoribosyltransferase (EC 2.4.2.7) Adenosine deaminase (EC 3.5.4.4) Adenosine kinase (EC 2.7.1.20) Adenylate kinase (EC 2.7.4.3) Adenylosuccinate lyase (EC 4.3.2.2) Adenylosuccinate synthetase (EC 6.3.4.4) Deoxyadenosine kinase (EC 2.7.1.76) Deoxyguanosine kinase (EC 2.7.1.113) Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1) GMP reductase GMP reductase (EC 1.7.1.7) GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) Guanine deaminase (EC 3.5.4.3) Guanylate kinase (EC 2.7.4.8) Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) IMP dehydrogenase related 1 (EC 1.1.1.205) IMP dehydrogenase related 2 (EC 1.7.1.7) Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) Inosine-guanosine kinase (EC 2.7.1.73) Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) Nucleoside diphosphate kinase (EC 2.7.4.6) Nucleotide pyrophosphatase (EC 3.6.1.9) Polyphosphate kinase (EC 2.7.4.1) Possible hypoxanthine oxidase XdhD (EC 1.-.-.-) Purine nucleoside phosphorylase (EC 2.4.2.1) Purine trans deoxyribosylase (Nucleoside deoxyribosyltransferase-I) (EC 2.4.2.6) Xanthine oxidase (EC 1.17.3.2) Xanthine phosphoribosyltransferase (EC 2.4.2.22) Xanthine-guanine phosphoribosyltransferase (EC 2.4.2.22) dATP pyrophosphohydrolase NudB (EC 3.6.1.-) preQ1-regulated inosine-uridine nucleoside hydrolase (EC 3.2.2.1) putative Adenosine kinase (EC 2.7.1.20) Purine_nucleotide_synthesis_regulator Purine nucleotide synthesis repressor Xanthine_Metabolism_in_Bacteria Hypoxanthine/guanine permease PbuG Nucleoside permease NupC Xanthine permease Xanthine phosphoribosyltransferase (EC 2.4.2.22) Xanthosine_utilization_(xap_region) Putative xanthosine permease Xanthosine operon regulatory protein XapR, LysR family Xanthosine permease Xanthosine permease pseudogene caused by IS154 insertion Xanthosine permease, C-terminus Xanthosine phosphorylase (EC 2.4.2.1) 02 Pyrimidines De_Novo_Pyrimidine_Synthesis Aspartate carbamoyltransferase (EC 2.1.3.2) Aspartate carbamoyltransferase regulatory chain (PyrI) Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) Carbamoyl-phosphate synthase large chain A (EC 6.3.5.5) Carbamoyl-phosphate synthase large chain B (EC 6.3.5.5) Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) Dihydroorotase (EC 3.5.2.3) Dihydroorotate dehydrogenase (EC 1.3.3.1) Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1) Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1) Orotate phosphoribosyltransferase (EC 2.4.2.10) Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) Pyrimidine operon regulatory protein PyrR Uracil permease Uracil phosphoribosyltransferase (EC 2.4.2.9) Novel_non-oxidative_pathway_of_Uracil_catabolism Allophanate hydrolase (EC 3.5.1.54) Beta-ureidopropionase (EC 3.5.1.6) Beta-ureidopropionase, eukaryotic type (EC 3.5.1.6) Dihydropyrimidinase (EC 3.5.2.2) Dihydropyrimidine dehydrogenase [NADP+] (EC 1.3.1.2) GTP cyclohydrolase II homolog Possible malonate-semialdehyde dehydrogenase in pyrimidine catabolism Possible pyrimidine permease in reductive pathway Possible pyrimidine regulator in Saccharomyces kluyveri Possible pyrimidine-degrading protein DUF1688 Uracil phosphoribosyltransferase (EC 2.4.2.9) Urea carboxylase (EC 6.3.4.6) Urease alpha subunit (EC 3.5.1.5) Urease beta subunit (EC 3.5.1.5) Urease gamma subunit (EC 3.5.1.5) Uridine kinase (EC 2.7.1.48) Pyrimidine_utilization Beta-ureidopropionase (EC 3.5.1.6) Dihydropyrimidinase (EC 3.5.2.2) Dihydropyrimidine dehydrogenase [NADP+] (EC 1.3.1.2) Possible hydrolase or acyltransferase RutD in novel pyrimidine catabolism pathway Possible pyrimidine permease in reductive pathway Possible ring-opening amidohydrolase RutC in novel pyrimidine catabolism pathway Predicted amidohydrolase RutB in novel pyrimidine catabolism pathway Predicted flavin reductase RutF in novel pyrimidine catabolism pathway Predicted monooxygenase RutA in novel pyrimidine catabolism pathway Predicted reductase RutE in novel pyrimidine catabolism pathway Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism Pyrimidine ABC transporter, ATP-binding protein Pyrimidine ABC transporter, substrate-binding component Pyrimidine ABC transporter, transmembrane component 1 Pyrimidine ABC transporter, transmembrane component 2 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) Uracil permease pyrimidine_conversions 2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16) 5'-nucleotidase (EC 3.1.3.5) Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) CTP synthase (EC 6.3.4.2) Cytidine deaminase (EC 3.5.4.5) Cytidylate kinase (EC 2.7.4.14) Cytosine deaminase (EC 3.5.4.1) Deoxycytidine triphosphate deaminase (EC 3.5.4.13) Deoxycytidine triphosphate deaminase (EC 3.5.4.30) (dUMP-forming) Nucleoside diphosphate kinase (EC 2.7.4.6) Purine nucleoside phosphorylase (EC 2.4.2.1) Purine trans deoxyribosylase (Nucleoside deoxyribosyltransferase-I) (EC 2.4.2.6) Pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) Thioredoxin reductase (EC 1.8.1.9) Thymidine kinase (EC 2.7.1.21) Thymidine phosphorylase (EC 2.4.2.4) Thymidylate kinase (EC 2.7.4.9) Thymidylate synthase (EC 2.1.1.45) Uracil phosphoribosyltransferase (EC 2.4.2.9) Uridine kinase (EC 2.7.1.48) Uridine kinase (EC 2.7.1.48) [C1] Uridine phosphorylase (EC 2.4.2.3) 02 AMP_to_3-phosphoglycerate AMP phosphohydrolase Ribose-1,5-bisphosphate isomerase Ribulose bisphosphate carboxylase (EC 4.1.1.39) Ribulose-1,5-bisphosphate carboxylase, Type III (EC 4.1.1.39) Adenosyl_nucleosidases 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase related protein BA2564 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase related protein BCZK2595 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase related protein BT9727_1702 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase related protein VF1653 Purine nucleoside phosphorylase (EC 2.4.2.1) S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) hydrolase, haloacid dehalogenase-like family protein BCZK2594 hypothetical protein Bcep3774, commonly clustered with carotenoid biosynthesis Hydantoin_metabolism Beta-ureidopropionase (EC 3.5.1.6) D-hydantoinase (EC 3.5.2.2) Deacetylases, including yeast histone deacetylase and acetoin utilization protein Dihydropyrimidinase (EC 3.5.2.2) Hydantoin permease Hydantoin racemase (EC 5.1.99.-) Hydantoin utilization protein A Hydantoinase N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) N-methylhydantoinase (ATP-hydrolyzing) (EC 3.5.2.14) N-methylhydantoinase A (EC 3.5.2.14) N-methylhydantoinase B (EC 3.5.2.14) hydantoin racemase Pseudouridine_Metabolism Hypothetical sugar kinase in cluster with indigoidine synthase indA , PfkB family of kinases Indigoidine synthase A-like protein, uncharacterized enzyme involved in pigment biosynthesis Inner membrane transport protein YeiM, in cluster with pseudouridine metabolism operon Probable pyrimidine nucleoside transport protein associated with pseudouridine catabolism Pseudouridine 5'-phosphate glycosidase Pseudouridine kinase (EC 2.7.1.83) Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) Uncharacterized sugar kinase YeiI Ribonucleotide_reduction Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1) Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1) Ribonucleotide reductase transcriptional regulator NrdR Ribonucleotide reduction protein NrdI 01 Phages, Prophages, Transposable elements 02 Bacteriophage integration/excision/lysogeny Phage_integration_and_excision DNA recombinase, phage-associated Integrase Integrase/recombinase (XerC/CodV family) Phage Holliday junction resolvase Phage endonuclease Phage excisionase Phage exonuclease Phage exonuclease (EC 3.1.11.3) Phage inihibitor of recBCD nuclease Phage integrase Phage resolvase Phage-associated recombinase Putative phage-encoded enzyme involved in integration-recombination RecA recombinase Site-specific recombinase Site-specific tyrosine recombinase Tyrosine recombinase xerC 02 Bacteriophage structural proteins Phage_capsid_proteins Capsid scaffolding protein Major capsid protein Minor capsid protein Phage capsid and scaffold Phage capsid assembly Phage capsid assembly protein Phage capsid protein Phage capsid scaffolding protein Phage capsid vertex Phage capsid vertex assembly chaperone Phage capsid vertex protein Phage head completion protein Phage head completion protein (GPL) Phage head-to-tail joining protein Phage major capsid protein Phage minor capsid protein Phage prohead core protein Prohead core scaffold protein and protease 02 Phage Host Interactions Phage_entry_and_exit Phage endolysin Phage endopeptidase Phage holin Phage host cell lysis Phage lysin Phage lysozyme Phage lysozyme (EC 3.2.1.17) Phage maturase Phage peptidoglycan binding endopeptidase Phage portal Phage rI lysis inhibition regulator Phage rIIA lysis inhibitor Phage rIIB lysis inhibitor 02 Superinfection Exclusion Phage_Dual_Exonuclease_Exclusion Exodeoxyribonuclease X (EC 3.1.11.-) Phage DNA and RNA binding protein Phage DNA binding ATPase Phage DNA binding protein HkaK Phage DNA repair protein Phage resistance protein Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 01 Phages, Prophages, Transposable elements, Plasmids 02 Pathogenicity islands Listeria_Pathogenicity_Island_LIPI-1_extended Actin-assembly inducing protein ActA precursor Broad-substrate range phospholipase C (EC 3.1.4.3) Distant similarity with viral glycoprotein gp160 of HIV type 1 Phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) Thiol-activated cytolysin Virulence regulatory factor PrfA Zinc metalloproteinase precursor (EC 3.4.24.29) virulence cluster protein A VclA virulence cluster protein B VclB Staphylococcal_pathogenicity_islands_SaPI CI-like repressor, superantigen-encoding pathogenicity islands SaPI Cro-like repressor, superantigen-encoding pathogenicity islands SaPI Degenerate integrase, superantigen-encoding pathogenicity islands SaPI Ferrichrome-binding periplasmic protein precursor in superantigen-encoding pathogenicity islands SaPI GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) Heat shock protein 60 family chaperone GroEL Hypothetical MW0753 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical MW0754 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAR0365 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAR0369 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAR0371 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAR0372 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAR0385 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0786 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0787 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0788 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0789 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0790 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0791 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0792 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0793 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0794 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0795 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0796 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0797 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0798 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0799 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0801 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV0808 homolog, near pathogenicity islands SaPI att-site Hypothetical SAV2026 homolog in superantigen-encoding pathogenicity islands SaPI Hypothetical SAV2027 homolog in superantigen-encoding pathogenicity islands SaPI Integrase, superantigen-encoding pathogenicity islands SaPI Methionine ABC transporter substrate-binding protein Putative DNA helicase, superantigen-encoding pathogenicity islands SaPI Putative primase, superantigen-encoding pathogenicity islands SaPI Putative terminase, superantigen-encoding pathogenicity islands SaPI SSU ribosomal protein S18p Secreted protein Ear, superantigen-encoding pathogenicity islands SaPI Superantigen enterotoxin SEB Superantigen enterotoxin SEK Superantigen enterotoxin SEL Toxic shock syndrome toxin 1 (TSST-1) tmRNA-binding protein SmpB Vibrio_pathogenicity_island Cytoplasmic, CoA-independent, aldehyde dehydrogenase (EC 1.2.1.3) Lipoprotein, ToxR-activated gene, TagA TCP pilin signal peptidase, TcpA processing TCP pilus virulence regulatory protein ToxT, transcription activator Toxin co-regulated pilin A Toxin co-regulated pilus biosynthesis protein B Toxin co-regulated pilus biosynthesis protein C, outer membrane protein Toxin co-regulated pilus biosynthesis protein D Toxin co-regulated pilus biosynthesis protein E, anchors TcpT to membrane Toxin co-regulated pilus biosynthesis protein F, putative outer membrane channel for TcpA extrusion Toxin co-regulated pilus biosynthesis protein H, transcriptional activator of ToxT promoter Toxin co-regulated pilus biosynthesis protein I, chemoreceptor, negative regulator of TcpA Toxin co-regulated pilus biosynthesis protein P, transcriptional activator of ToxT promoter Toxin co-regulated pilus biosynthesis protein Q Toxin co-regulated pilus biosynthesis protein R Toxin co-regulated pilus biosynthesis protein S Toxin co-regulated pilus biosynthesis protein T, putative ATP-binding translocase of TcpA 02 Phage family-specific subsystems T7-like_cyanophage_core_proteins Phage-encoded high light-inducible protein, HliP Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) T7-like cyanophage core protein, T7 GC51 T7-like cyanophage core protein, T7 GC53 T7-like cyanophage core protein, T7 GC54 T7-like cyanophage core protein, T7 GC55 Transaldolase (EC 2.2.1.2) photosystem II protein D1 (PsbA) T7-like_non-cyanophage_core_proteins DNA packaging protein A, T7-like gp18 Host RNA polymerase inhibitor, T7-like gp2 Host protein H-NS-interacting protein, T7-like gp5.5-5.7 Phage holin, class II Phage lysin, N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) 02 Phages, Prophages Listeria_phi-A118-like_prophages Antirepressor [Bacteriophage A118] Endolysin, L-alanyl-D-glutamate peptidase (EC 3.4.-.-) [Bacteriophage A118] Holin [Bacteriophage A118] Hypothetical protein, Lin0079 homolog [Bacteriophage A118] Hypothetical protein, Lmo2276 homolog Hypothetical protein, Lmo2305 homolog [Bacteriophage A118] Hypothetical protein, Lmo2306 homolog [Bacteriophage A118] Hypothetical protein, Lmo2307 homolog [Bacteriophage A118] Hypothetical protein, Lmo2313 homolog [Bacteriophage A118] Integrase [Bacteriophage A118] Lactobacillus delbrueckii phage mv4 main capsid protein Gp34 homolog lin2390 Major capsid protein [Bacteriophage A118] Major tail shaft protein [Bacteriophage A118] Minor capsid protein [Bacteriophage A118] Portal protein [Bacteriophage A118] Protein gp10 [Bacteriophage A118] Protein gp11 [Bacteriophage A118] Protein gp13 [Bacteriophage A118] Protein gp14 [Bacteriophage A118] Protein gp15 [Bacteriophage A118] Protein gp22 [Bacteriophage A118] Protein gp23 [Bacteriophage A118] Protein gp28 [Bacteriophage A118] Protein gp29 [Bacteriophage A118] Protein gp30 [Bacteriophage A118] Protein gp32 [Listeria phage 2389] Protein gp33 [Bacteriophage A118] Protein gp34 [Bacteriophage A118] Protein gp35 [Bacteriophage A118] Protein gp37 [Bacteriophage A118] Protein gp38 [Bacteriophage A118] Protein gp40 [Bacteriophage A118] Protein gp41 [Bacteriophage A118] Protein gp43 [Bacteriophage A118] Protein gp44 [Bacteriophage A118] Protein gp45 [Bacteriophage A118] Protein gp47, recombination-related [Bacteriophage A118] Protein gp49, replication initiation [Bacteriophage A118] Protein gp51 [Bacteriophage A118] Protein gp52 [Bacteriophage A118] Protein gp55 [Bacteriophage A118] Protein gp59 [Bacteriophage A118] Protein gp61 [Bacteriophage A118], similar to Listeria protein LmaD Protein gp63 [Bacteriophage A118] Protein gp65 [Bacteriophage A118] Protein gp66 [Bacteriophage A118], similar to Listeria protein LmaC Protein gp68 [Bacteriophage A118] Protein gp7 [Bacteriophage A118] Protein gp8 [Bacteriophage A118] Protein gp9 [Bacteriophage A118] Putative long tail fibre [Bacteriophage A118] Putative short tail fibre [Bacteriophage A118] Putative tail or base plate protein gp17 [Bacteriophage A118] Putative tail or base plate protein gp18 [Bacteriophage A118] Putative tail or base plate protein gp19 [Bacteriophage A118] Recombinational DNA repair protein RecT (prophage associated) Repressor (CI-like) [Bacteriophage A118] Repressor (cro-like) [Bacteriophage A118] Scaffolding protein [Bacteriophage A118] Similar to terminase small subunit, yqaS homolog Single-stranded DNA-binding protein (prophage associated) Tail tape-measure protein [Bacteriophage A118] Terminase large subunit [Bacteriophage A118] Terminase small subunit [Bacteriophage A118] Terminase, large subunit [Bacteriophage PhiNIH1.1] Phage_Ea_cluster Phage EaA protein Phage EaA2 protein Phage EaC protein Phage EaD protein Phage EaE protein Phage EaF protein Phage EaG protein Phage EaI protein Phage_baseplate_proteins Phage baseplate Phage baseplate distal hub Phage baseplate hub Phage baseplate protein Phage baseplate tail tube cap Phage baseplate wedge Phage baseplate wedge initiator Phage baseplate-tail tube initiator Phage_neck_proteins Phage collar Phage neck Phage neck protein Phage neck whiskers Phage_nin_genes_-_N-independent_survival Phage Nin protein Phage NinA Phage NinB DNA recombination Phage NinC Phage NinD Phage NinE Phage NinF Phage NinG rap recombination Phage NinH Phage NinX Phage NinY Phage antitermination protein N Phage antitermination protein Q Phage_packaging_machinery Phage DNA binding protein Phage DNA packaging Phage DNA-packaging protein Phage portal Phage portal protein Phage terminase Phage terminase large subunit Phage terminase large subunit, PBSX family Phage terminase small subunit Phage terminase, large subunit Phage terminase, small subunit Phage_tail_fiber_proteins Phage long tail fiber proximal connector Phage long tail fiber proximal subunit Phage tail fiber assembly protein Phage tail fiber protein Phage tail fibers Phage tail fibers chaperone Tail fiber protein [SA bacteriophages 11, Mu50B] Phage_tail_proteins_2 Phage major tail protein Phage major tail shaft protein Phage minor tail protein Phage tail assembly Phage tail assembly chaperone Phage tail assembly protein Phage tail assembly protein I Phage tail completion protein Phage tail connector Phage tail length tape-measure protein Phage tail length tape-measure protein 1 Phage tail sheath monomer Phage tape measure Prophage-encoded_Rst_operon RstA phage-related replication protein RstA phage-related replication protein, frameshift RstA phage-related replication protein, truncated RstB phage-related integrase RstC phage-related antirepressor RstR phage-related transcriptional repressor Prophage_lysogenic_conversion_modules Holin Paratox Phage hyaluronidase Phage-associated cell wall hydrolase _Toximoron (Other) _Toximoron (Superantigen) Staphylococcal_phi-Mu50B-like_prophages Antirepressor [SA bacteriophages 11, Mu50B] Autolysin [SA bacteriophages 11, Mu50B] CI-like repressor [SA bacteriophages 11, Mu50B] Cro-like repressor [SA bacteriophages 11, Mu50B] DNA binding protein [SA bacteriophages 11, Mu50B] DNA helicase [SA bacteriophages 11, Mu50B] Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) [SA bacteriophages 11, Mu50B] Excisionase [SA bacteriophages 11, Mu50B] Holin [SA bacteriophages 11, Mu50B] Hypothetical protein [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf 20 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf10 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf12 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf19 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf22 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf23 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf3 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PV83 orf4 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PVL orf39 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PVL orf50 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PVL orf51 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, PVL orf52 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAB1734c homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAB1742c homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0849 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0852 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0860 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0876 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0877 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0878 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0879 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0880 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SAV0881 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SLT orf81b homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, SLT orf99 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf16 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf17 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf24 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf33 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf42 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf55 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf58 homolog [SA bacteriophages 11, Mu50B] Hypothetical protein, phi-ETA orf63 homolog [SA bacteriophages 11, Mu50B] Integrase [SA bacteriophages 11, Mu50B] Integrase regulator RinA [SA bacteriophages 11, Mu50B] Integrase regulator RinB [SA bacteriophages 11, Mu50B] Iron-sulfur cluster assembly protein SufB Lytic enzyme, amidase [SA bacteriophages 11, Mu50B] Phage head protein [SA bacteriophages 11, Mu50B] Phage terminase, large subunit [SA bacteriophages 11, Mu50B] Phage terminase, small subunit [SA bacteriophages 11, Mu50B] Putative major teichoic acid biosynthesis protein C Ssb protein [SA bacteriophages 11, Mu50B] Tail fiber protein [SA bacteriophages 11, Mu50B] Tape measure protein [SA bacteriophages 11, Mu50B] phi 11 orf31 homolog [SA bacteriophages 11, Mu50B] phi 11 orf32 homolog [SA bacteriophages 11, Mu50B] phi 11 orf33 homolog [SA bacteriophages 11, Mu50B] phi 11 orf35 homolog [SA bacteriophages 11, Mu50B] phi 11 orf36 homolog [SA bacteriophages 11, Mu50B] phi 11 orf37 homolog [SA bacteriophages 11, Mu50B] phi 11 orf38 homolog [SA bacteriophages 11, Mu50B] phi 11 orf39 homolog [SA bacteriophages 11, Mu50B] phi 11 orf40 homolog [SA bacteriophages 11, Mu50B] phi 11 orf41 homolog [SA bacteriophages 11, Mu50B] phi 11 orf43 homolog [SA bacteriophages 11, Mu50B] T7-like_phage_core_proteins T7-like phage DNA Polymerase (EC 2.7.7.7) T7-like phage DNA maturase B T7-like phage DNA-directed RNA polymerase (EC 2.7.7.6) T7-like phage endonuclease (EC 3.1.21.2) T7-like phage exonuclease (EC 3.1.11.3) T7-like phage head-to-tail joining protein T7-like phage internal protein A T7-like phage major/minor capsid protein T7-like phage primase/helicase protein T7-like phage scaffolding protein T7-like phage ssDNA-binding protein T7-like phage tail fiber protein T7-like phage tail tubular protein A T7-like phage tail tubular protein B 02 Plasmid related functions Plasmid-encoded_T-DNA_transfer ATPase required for both assembly of type IV secretion complex and secretion of T-DNA complex, VirB11 ATPase required for both assembly of type IV secretion complex and secretion of T-DNA complex, VirB4 Coupling protein VirD4, ATPase required for T-DNA transfer Inner membrane protein of type IV secretion of T-DNA complex, TonB-like, VirB10 Inner membrane protein of type IV secretion of T-DNA complex, VirB3 Inner membrane protein of type IV secretion of T-DNA complex, VirB6 Inner membrane protein of type IV secretion of T-DNA complex, VirB8 Major pilus subunit of type IV secretion complex, VirB2 Minor pilin of type IV secretion complex, VirB5 Outer membrane and periplasm component of type IV secretion of T-DNA complex, has secretin-like domain, VirB9 Peptidoglycan hydrolase VirB1, involved in T-DNA transfer Plant-inducible protein PinF1, cytochrome P450-like, contributes to virulence Plant-inducible protein PinF2, cytochrome P450-like, contributes to virulence Protein VirD5 in virD operon Protein VirF secreted into plant cell during T-DNA transfer RHH DNA-binding protein VirC2, promotes T-DNA transfer T-DNA border endonuclease VirD2, RP4 TraG-like relaxase T-DNA border endonuclease, VirD1 Two-component response regulator of vir regulon, VirG Two-component sensor kinase of vir regulon, VirA VirC1 protein promotes T-DNA transfer, ParA/MinD-like VirD3 protein VirE0 protein, induced by VirAG signaling system VirE2 involved in nuclear transport of T-DNA, single-strand DNA binding protein VirE3 involved in nuclear transport of T-DNA, potential plant transcriptional activator Rolling-circle_replication Replication initiation protein, topisomerase 02 Transposable elements CBSS-203122.12.peg.188 ComM-related protein FIGfam050825 FIGfam110555 ISPsy4, transposase ISPsy4, transposition helper protein Integrase/recombinase clustered with segregation and condensation protein B MG(2+) CHELATASE FAMILY PROTEIN Mll9366 protein Plasmid replication protein RepA Predicted nucleotidyltransferases Resolvase/Integrase TinR protein Segregation and condensation protein B TniA putative transposase TniB NTP-binding protein TniQ Transposase OrfAB, subunit B protein of unknown function DUF1403 protein of unknown function DUF1612 Conjugative_transposon,_Bacteroidales Conjugative transposon protein TraA Conjugative transposon protein TraB Conjugative transposon protein TraC Conjugative transposon protein TraD Conjugative transposon protein TraE Conjugative transposon protein TraF Conjugative transposon protein TraG Conjugative transposon protein TraH Conjugative transposon protein TraI Conjugative transposon protein TraJ Conjugative transposon protein TraK Conjugative transposon protein TraL Conjugative transposon protein TraM Conjugative transposon protein TraN Conjugative transposon protein TraO Conjugative transposon protein TraP Conjugative transposon protein TraQ Putative conjugative transposon mobilization protein BF0132 Putative mobilization protein BF0133 hypothetical protein clusted with conjugative transposons, BF0131 Tn552 ATP-binding protein p271 Beta-lactamase (EC 3.5.2.6) Beta-lactamase regulatory sensor-transducer BlaR1 Beta-lactamase repressor BlaI Resolvase/integrase Bin Tn552 transposase 02 Integrons Integron integrase Integron integrase IntI1 Integron integrase IntI2 Integron integrase IntI4 Integron integrase IntIPac 01 Phosphorus Metabolism Alkylphosphonate_utilization ATP-binding protein PhnN Alkylphosphonate utilization operon protein PhnA Metal-dependent hydrolase involved in phosphonate metabolism PhnB protein PhnG protein PhnH protein PhnI protein PhnJ protein PhnO protein Phosphonates transport ATP-binding protein PhnK Phosphonates transport ATP-binding protein PhnL Protein RcsF Transcriptional regulator PhnF High_affinity_phosphate_transporter_and_control_of_PHO_regulon Alkaline phosphatase synthesis transcriptional regulatory protein PhoP Distant similarity with phosphate transport system regulator Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3) Phosphate regulon transcriptional regulatory protein PhoB (SphR) Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) Phosphate transport system permease protein PstA (TC 3.A.1.7.1) Phosphate transport system permease protein PstC (TC 3.A.1.7.1) Phosphate transport system regulatory protein PhoU Polyphosphate kinase (EC 2.7.4.1) Putative periplasmic phosphate-binding protein PstS (Catenulisporaceae type) Putative periplasmic phosphate-binding protein PstS (Halobacteriales type) Putative periplasmic phosphate-binding protein PstS (Mycoplasma type) P_uptake_(cyanobacteria) Alkaline phosphatase (EC 3.1.3.1) Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) Phosphate regulon sensor protein PhoR (EC 2.7.3.-) Phosphate regulon transcriptional regulatory protein PhoB Phosphate starvation-inducible protein PhoH Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) Phosphate transport system permease protein PstA (TC 3.A.1.7.1) Phosphate transport system permease protein PstC (TC 3.A.1.7.1) Phosphate_metabolism 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) Alkaline phosphatase (EC 3.1.3.1) Alkaline phosphatase like protein Alkaline phosphatase synthesis transcriptional regulatory protein PhoP Apolipoprotein N-acyltransferase (EC 2.3.1.-) Distant similarity with phosphate transport system regulator Exopolyphosphatase (EC 3.6.1.11) FIG000233: metal-dependent hydrolase Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC 3.6.1.40) Inorganic pyrophospatase PpaX (EC 3.1.3.18) Inorganic pyrophosphatase (EC 3.6.1.1) Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) Low-affinity inorganic phosphate transporter Magnesium and cobalt efflux protein CorC Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1) NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) Na/Pi cotransporter II-related protein Phosphatase, Ppx/GppA family Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3) Phosphate regulon transcriptional regulatory protein PhoB (SphR) Phosphate starvation-inducible ATPase PhoH with RNA binding motif Phosphate starvation-inducible protein PhoH, predicted ATPase Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) Phosphate transport regulator (distant homolog of PhoU) Phosphate transport system permease protein PstA (TC 3.A.1.7.1) Phosphate transport system permease protein PstC (TC 3.A.1.7.1) Phosphate transport system regulatory protein PhoU Phosphate-specific outer membrane porin OprP Polyphosphate kinase (EC 2.7.4.1) Predicted ATPase related to phosphate starvation-inducible protein PhoH Probable low-affinity inorganic phosphate transporter Putative periplasmic phosphate-binding protein PstS (Mycoplasma type) Pyrophosphate-energized proton pump (EC 3.6.1.1) Pyrophosphate-specific outer membrane porin OprO Sodium-dependent phosphate transporter Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) putative alkaline phosphatase-like protein response regulator in two-component regulatory system with PhoQ secreted alkaline phosphatase Phosphoenolpyruvate_phosphomutase 2-aminoethylphosphonate:pyruvate aminotransferase (EC 2.6.1.37) Phosphoenolpyruvate phosphomutase (EC 5.4.2.9) Phosphonopyruvate decarboxylase (EC 4.1.1.82) Phosphonate_metabolism 2-aminoethylphosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1) 2-aminoethylphosphonate ABC transporter periplasmic binding component (TC 3.A.1.9.1) 2-aminoethylphosphonate ABC transporter permease protein I (TC 3.A.1.9.1) 2-aminoethylphosphonate ABC transporter permease protein II (TC 3.A.1.9.1) 2-aminoethylphosphonate uptake and metabolism regulator 2-aminoethylphosphonate:pyruvate aminotransferase (EC 2.6.1.37) Phosphonate uptake and metabolism regulator, LysR-family Phosphonoacetaldehyde hydrolase (EC 3.11.1.1) Phosphonoacetate hydrolase (EC 3.11.1.2) 01 Photosynthesis 02 Electron transport and photophosphorylation Photosystem_I alternative photosystem I reaction center subunit X (PsaK2) photosystem I 4.8K protein (PsaX) photosystem I P700 chlorophyll a apoprotein subunit Ia (PsaA) photosystem I P700 chlorophyll a apoprotein subunit Ib (PsaB) photosystem I assembly related protein Ycf3 photosystem I assembly related protein Ycf37 photosystem I assembly related protein Ycf4 photosystem I biogenesis protein BtpA photosystem I iron-sulfur center subunit VII (PsaC) photosystem I subunit II (PsaD) photosystem I subunit III precursor, plastocyanin (cyt c553) docking protein (PsaF) photosystem I subunit IV (PsaE) photosystem I subunit IX (PsaJ) photosystem I subunit VIII (PsaI) photosystem I subunit X (PsaK, PsaK1) photosystem I subunit XI (PsaL) photosystem I subunit XII (PsaM) Photosystem_I-type_photosynthetic_reaction_center Photosystem P840 reaction center iron-sulfur subunit PscB Photosystem P840 reaction center large subunit PscA Photosystem P840 reaction center subunit PscC, cytochrome c-551 Photosystem P840 reaction center subunit PscD Photosystem_II Chlorophyll a(b) binding protein, photosystem II CP43 protein (PsbC) homolog Cytochrome b559 alpha chain (PsbE) Cytochrome b559 beta chain (PsbF) Photosystem II 10 kDa phosphoprotein (PsbH) Photosystem II 12 kDa extrinsic protein (PsbU) Photosystem II 13 kDa protein Psb28 (PsbW) Photosystem II CP43 protein (PsbC) Photosystem II CP47 protein (PsbB) Photosystem II manganese-stabilizing protein (PsbO) Photosystem II oxygen evolving complex protein PsbP Photosystem II protein Psb27 Photosystem II protein PsbI Photosystem II protein PsbJ Photosystem II protein PsbK Photosystem II protein PsbL Photosystem II protein PsbM Photosystem II protein PsbN Photosystem II protein PsbT Photosystem II protein PsbV, cytochrome c550 Photosystem II protein PsbX Photosystem II protein PsbY Photosystem II protein PsbZ Photosystem II stability/assembly factor HCF136/Ycf48 Putative chaperon-like protein Ycf39 for quinone binding in Photosystem II photosystem II protein D1 (PsbA) photosystem II protein D2 (PsbD) Photosystem_II-type_photosynthetic_reaction_center Light-harvesting LHI, alpha subunit Light-harvesting LHI, beta subunit Photosynthetic reaction center H subunit Photosynthetic reaction center L subunit Photosynthetic reaction center M subunit Photosynthetic reaction center cytochrome c subunit Protein PufQ, involved in assembly of B875 and B800-850 pigment-protein complexes Protein PufX, involved in assembly of B875 and B800-850 pigment-protein complexes Putative photosynthetic complex assembly protein 02 Light-harvesting complexes Bacterial_light-harvesting_proteins Light-harvesting LHI, alpha subunit Light-harvesting LHI, beta subunit Light-harvesting LHII, alpha subunit A Light-harvesting LHII, alpha subunit B Light-harvesting LHII, alpha subunit C Light-harvesting LHII, alpha subunit D Light-harvesting LHII, alpha subunit E Light-harvesting LHII, alpha subunit F Light-harvesting LHII, alpha subunit G Light-harvesting LHII, beta subunit A Light-harvesting LHII, beta subunit B Light-harvesting LHII, beta subunit C Light-harvesting LHII, beta subunit D Light-harvesting LHII, beta subunit E Light-harvesting LHII, beta subunit F Light-harvesting LHII, beta subunit G Protein PufQ, involved in assembly of B875 and B800-850 pigment-protein complexes Chlorosome Chlorosome protein A Chlorosome protein B Chlorosome protein C Chlorosome protein D Chlorosome protein E Chlorosome protein F Chlorosome protein H Chlorosome protein I, 2Fe-2S ferredoxin Chlorosome protein J, 2Fe-2S ferredoxin Chlorosome protein X Phycobilisome Allophycocyanin alpha chain Allophycocyanin beta chain Allophycocyanin-B CpeR homolog, phycoerythrin linker-proteins region Phycobilisome core component Phycobilisome core-membrane linker polypeptide Phycobilisome degradation protein NblA Phycobilisome phycoerythrin-associated linker polypeptide Phycobilisome rod linker polypeptide, phycocyanin-associated Phycobilisome rod linker polypeptide, phycoerythrocyanin-associated Phycobilisome rod-core linker polypeptide, phycocyanin-associated Phycobilisome small core linker polypeptide Phycobilisome small rod capping linker polypeptide, phycocyanin-associated Phycocyanin alpha chain Phycocyanin alpha phycocyanobilin lyase related protein NblB Phycocyanin beta chain Phycocyanobilin lyase alpha subunit Phycocyanobilin lyase beta subunit Phycoerythrin alpha chain Phycoerythrin beta chain Phycoerythrin gamma chain linker polypeptide Phycoerythrin linker protein CpeS homolog Phycoerythrocyanin alpha chain Phycoerythrocyanin beta chain 02 Bacteriorhodopsin Bacteriorhodopsin Bacteriorhodopsin related protein Blp Bacteriorhodopsin related protein Brp, likely catalyses oxidative cleavage of beta?carotene to retinal Brp-like protein Geranylgeranyl-diphosphate geranylgeranyl-transferase Protein CrtB1 involved in bacteriorhodopsin synthesis Transcription regulator Bat, regulates bacteriorhodopsin synthesis Proteorhodopsin Beta-carotene ketolase (EC 1.14.-.-) Lycopene beta cyclase (EC 1.14.-.-) Lycopene cyclase, CruA type Octaprenyl-diphosphate synthase (EC 2.5.1.-) Phytoene dehydrogenase (EC 1.14.99.-) Phytoene synthase (EC 2.5.1.32) Predictet Brp-like protein Blh Proteorhodopsin Spheroidene monooxygenase 01 Plasmids 02 Plasmid replication F_plasmid_replication CcdA protein (antitoxin to CcdB) CcdB toxin protein Plasmid SOS inhibition protein PsiA Plasmid SOS inhibition protein PsiB Plasmid partition protein A Plasmid partition protein B RepFIB associated resolvase RepFIB replication protein A RepFIC associated resolvase RepFIC replication protein C Replication initiation protein RepE 01 Potassium metabolism Glutathione-regulated_potassium-efflux_system_and_associated_functions Glutathione-regulated potassium-efflux system ATP-binding protein Glutathione-regulated potassium-efflux system ancillary protein KefF Glutathione-regulated potassium-efflux system ancillary protein KefG Glutathione-regulated potassium-efflux system protein KefB Potassium efflux system YjeP Potassium efflux system f786 Trk system potassium uptake protein TrkA Hyperosmotic_potassium_uptake Potassium uptake protein, integral membrane component, KtrA Potassium uptake protein, integral membrane component, KtrB Potassium uptake protein, integral membrane component, KtrD Potassium_homeostasis Binding-protein-dependent transport systems inner membrane component:ATP/GTP-binding site motif A (P-loop) :TrkA-N:Potassium e FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8) FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) Glutathione-regulated potassium-efflux system ATP-binding protein Glutathione-regulated potassium-efflux system ancillary protein KefF Glutathione-regulated potassium-efflux system ancillary protein KefG Glutathione-regulated potassium-efflux system protein KefC Glutathione-regulated potassium-efflux system protein KefKL K transporter trk Kef-type K+ transport systems (NAD-binding component fused to domain related to exopolyphosphatase) Kef-type transport system 2 (probable substrate potassium), subunit 1 Kef-type transport system 2 (probable substrate potassium), subunit 2 Kup system potassium uptake protein Large-conductance mechanosensitive channel Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) POTASSIUM/PROTON ANTIPORTER ROSB Possible potassium-efflux system protein Potassium channel protein Potassium channel protein 1 (MjK1) Potassium efflux system KefA protein Potassium uptake protein TrkH Potassium uptake protein, integral membrane component, KtrA Potassium uptake protein, integral membrane component, KtrB Potassium voltage-gated channel subfamily KQT Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1) Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1) Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1) Putative cytoplasmic protein ,probably associated with Glutathione-regulated potassium-efflux Trk system potassium uptake protein TrkA Trk system potassium uptake protein TrkG TrkA-N:Sodium/hydrogen exchanger Voltage-gated potassium channel cAMP-dependent Kef-type K+ transport system putative Glutathione-regulated potassium-efflux system protein KefB pH_adaptation_potassium_efflux_system pH adaptation potassium efflux system a pH adaptation potassium efflux system c pH adaptation potassium efflux system d pH adaptation potassium efflux system e pH adaptation potassium efflux system f pH adaptation potassium efflux system g pH adaption potassium efflux system protein PhaD pH adaption potassium efflux system protein PhaE pH adaption potassium efflux system protein PhaF pH adaption potassium efflux system protein PhaG 01 Protein Metabolism 02 Protein biosynthesis Nucleolar_protein_complex Collagen alpha 1(I) chain precursor SSU ribosomal protein S14e (S11p) Programmed_frameshift Peptide chain release factor 2 Peptide chain release factor 2 unshifted fragment programmed frameshift-containing Pyrrolysine Proline 2-methylase for pyrrolysine biosynthesis Proline reductase for pyrrolysine biosynthesis Pyrrolysine synthetase Pyrrolysyl-tRNA synthetase (EC 6.1.1.26) pyrrolysine-containing Ribosomal_protein_paralogs Similar to ribosomal protein L11p Ribosome_LSU_bacterial Firmicutes ribosomal L7Ae family protein LSU ribosomal protein L10p (P0) LSU ribosomal protein L11p (L12e) LSU ribosomal protein L13p (L13Ae) LSU ribosomal protein L14p (L23e) LSU ribosomal protein L15p (L27Ae) LSU ribosomal protein L16p (L10e) LSU ribosomal protein L17p LSU ribosomal protein L18p (L5e) LSU ribosomal protein L19p LSU ribosomal protein L1p (L10Ae) LSU ribosomal protein L20p LSU ribosomal protein L21p LSU ribosomal protein L22p (L17e) LSU ribosomal protein L23p (L23Ae) LSU ribosomal protein L24p (L26e) LSU ribosomal protein L25p LSU ribosomal protein L27p LSU ribosomal protein L28p LSU ribosomal protein L29p (L35e) LSU ribosomal protein L2p (L8e) LSU ribosomal protein L30p (L7e) LSU ribosomal protein L31p LSU ribosomal protein L32p LSU ribosomal protein L33p LSU ribosomal protein L34p LSU ribosomal protein L35p LSU ribosomal protein L36p LSU ribosomal protein L3p (L3e) LSU ribosomal protein L4p (L1e) LSU ribosomal protein L5p (L11e) LSU ribosomal protein L6p (L9e) LSU ribosomal protein L7/L12 (P1/P2) LSU ribosomal protein L9p Ribosome_LSU_chloroplast LSU ribosomal protein L10p (P0), chloroplast LSU ribosomal protein L11p (L12e), chloroplast LSU ribosomal protein L13p (L13Ae), chloroplast LSU ribosomal protein L14p (L23e), chloroplast LSU ribosomal protein L15p (L27Ae), chloroplast LSU ribosomal protein L16p (L10e), chloroplast LSU ribosomal protein L17p, chloroplast LSU ribosomal protein L18p (L5e), chloroplast LSU ribosomal protein L19p, chloroplast LSU ribosomal protein L1p (L10Ae), chloroplast LSU ribosomal protein L20p, chloroplast LSU ribosomal protein L21p, chloroplast LSU ribosomal protein L22p (L17e), chloroplast LSU ribosomal protein L23p (L23Ae), chloroplast LSU ribosomal protein L24p (L26e), chloroplast LSU ribosomal protein L27p, chloroplast LSU ribosomal protein L28p, chloroplast LSU ribosomal protein L29p (L35e), chloroplast LSU ribosomal protein L2p (L8e), chloroplast LSU ribosomal protein L31p, chloroplast LSU ribosomal protein L32p, chloroplast LSU ribosomal protein L33p, chloroplast LSU ribosomal protein L34p, chloroplast LSU ribosomal protein L35p, chloroplast LSU ribosomal protein L36p, chloroplast LSU ribosomal protein L3p (L3e), chloroplast LSU ribosomal protein L4p (L1e), chloroplast LSU ribosomal protein L5p (L11e), chloroplast LSU ribosomal protein L6p (L9e), chloroplast LSU ribosomal protein L7/L12 (L23e), chloroplast LSU ribosomal protein L9p, chloroplast Ribosome_LSU_eukaryotic_and_archaeal LSU ribosomal protein L10Ae (L1p) LSU ribosomal protein L10e (L16p) LSU ribosomal protein L11e (L5p) LSU ribosomal protein L12a (P1/P2) LSU ribosomal protein L12e (L11p) LSU ribosomal protein L13Ae (L13p) LSU ribosomal protein L13e LSU ribosomal protein L14e LSU ribosomal protein L15e LSU ribosomal protein L17e (L22p) LSU ribosomal protein L18Ae LSU ribosomal protein L18e LSU ribosomal protein L19e LSU ribosomal protein L1e (L4p) LSU ribosomal protein L21e LSU ribosomal protein L23Ae (L23p) LSU ribosomal protein L23e (L14p) LSU ribosomal protein L24e LSU ribosomal protein L26e (L24p) LSU ribosomal protein L27Ae (L15p) LSU ribosomal protein L30e LSU ribosomal protein L31e LSU ribosomal protein L32e LSU ribosomal protein L34e LSU ribosomal protein L35Ae LSU ribosomal protein L35e (L29p) LSU ribosomal protein L37Ae LSU ribosomal protein L37e LSU ribosomal protein L38e LSU ribosomal protein L39e LSU ribosomal protein L3e (L3p) LSU ribosomal protein L40e LSU ribosomal protein L41e LSU ribosomal protein L44e LSU ribosomal protein L5e (L18p) LSU ribosomal protein L7Ae LSU ribosomal protein L7e (L30p) LSU ribosomal protein L8e (L2p) LSU ribosomal protein L9e (L6p) LSU ribosomal protein P0 (L10p) Ribosome_LSU_mitochondrial LSU ribosomal protein L10p (P0), mitochondrial LSU ribosomal protein L11p (L12e), mitochondrial LSU ribosomal protein L13p (L13Ae), mitochondrial LSU ribosomal protein L14p (L23e), mitochondrial LSU ribosomal protein L15p (L27Ae), mitochondrial LSU ribosomal protein L16p (L10e), mitochondrial LSU ribosomal protein L17p, mitochondrial LSU ribosomal protein L18p (L5e), mitochondrial LSU ribosomal protein L19p, mitochondrial LSU ribosomal protein L1p (L10Ae), mitochondrial LSU ribosomal protein L20p, mitochondrial LSU ribosomal protein L21p, mitochondrial LSU ribosomal protein L22p (L17e), mitochondrial LSU ribosomal protein L23p (L23Ae), mitochondrial LSU ribosomal protein L24p (L26e), mitochondrial LSU ribosomal protein L25p, mitochondrial LSU ribosomal protein L27p, mitochondrial LSU ribosomal protein L28p, mitochondrial LSU ribosomal protein L29p (L35e), mitochondrial LSU ribosomal protein L2p (L8e), mitochondrial LSU ribosomal protein L30p (L7e), mitochondrial LSU ribosomal protein L31p, mitochondrial LSU ribosomal protein L32p, mitochondrial LSU ribosomal protein L33p, mitochondrial LSU ribosomal protein L34p, mitochondrial LSU ribosomal protein L35p, mitochondrial LSU ribosomal protein L36p, mitochondrial LSU ribosomal protein L37mt, mitochondrial LSU ribosomal protein L38mt, mitochondrial LSU ribosomal protein L39mt, mitochondrial LSU ribosomal protein L3p (L3e), mitochondrial LSU ribosomal protein L40mt, mitochondrial LSU ribosomal protein L41mt, mitochondrial LSU ribosomal protein L42mt, mitochondrial LSU ribosomal protein L43mt, mitochondrial LSU ribosomal protein L44mt, mitochondrial LSU ribosomal protein L45mt, mitochondrial LSU ribosomal protein L46mt, mitochondrial LSU ribosomal protein L47mt, mitochondrial LSU ribosomal protein L48mt, mitochondrial LSU ribosomal protein L49mt, mitochondrial LSU ribosomal protein L4p (L1e), mitochondrial LSU ribosomal protein L50mt, mitochondrial LSU ribosomal protein L51mt, mitochondrial LSU ribosomal protein L52mt, mitochondrial LSU ribosomal protein L53mt, mitochondrial LSU ribosomal protein L54mt, mitochondrial LSU ribosomal protein L55mt, mitochondrial LSU ribosomal protein L5p (L11e), mitochondrial LSU ribosomal protein L6p (L9e), mitochondrial LSU ribosomal protein L7/L12 (L23e), mitochondrial LSU ribosomal protein L9p, mitochondrial LSU ribosomal protein MRP51, mitochondrial LSU ribosomal protein MRPL13, mitochondrial LSU ribosomal protein MRPL15, mitochondrial LSU ribosomal protein MRPL20, mitochondrial LSU ribosomal protein MRPL25, mitochondrial LSU ribosomal protein MRPL31, mitochondrial LSU ribosomal protein MRPL35, mitochondrial Ribosome_SSU_bacterial SSU ribosomal protein S10p (S20e) SSU ribosomal protein S11p (S14e) SSU ribosomal protein S12p (S23e) SSU ribosomal protein S13p (S18e) SSU ribosomal protein S14p (S29e) SSU ribosomal protein S15p (S13e) SSU ribosomal protein S16p SSU ribosomal protein S17p (S11e) SSU ribosomal protein S18p SSU ribosomal protein S19p (S15e) SSU ribosomal protein S1p SSU ribosomal protein S20p SSU ribosomal protein S21p SSU ribosomal protein S2p (SAe) SSU ribosomal protein S3p (S3e) SSU ribosomal protein S4p (S9e) SSU ribosomal protein S5p (S2e) SSU ribosomal protein S6p SSU ribosomal protein S7p (S5e) SSU ribosomal protein S8p (S15Ae) SSU ribosomal protein S9p (S16e) SSU ribosomal protein Thx Ribosome_SSU_chloroplast SSU ribosomal protein S10p (S20e), chloroplast SSU ribosomal protein S11p (S14e), chloroplast SSU ribosomal protein S12p (S23e), chloroplast SSU ribosomal protein S13p (S18e), chloroplast SSU ribosomal protein S14p (S29e), chloroplast SSU ribosomal protein S15p (S13e), chloroplast SSU ribosomal protein S16p, chloroplast SSU ribosomal protein S17p (S11e), chloroplast SSU ribosomal protein S18p, chloroplast SSU ribosomal protein S19p (S15e), chloroplast SSU ribosomal protein S1p, chloroplast SSU ribosomal protein S20p, chloroplast SSU ribosomal protein S2p (SAe), chloroplast SSU ribosomal protein S3p (S3e), chloroplast SSU ribosomal protein S4p (S9e), chloroplast SSU ribosomal protein S5p (S2e), chloroplast SSU ribosomal protein S6p, chloroplast SSU ribosomal protein S7p (S5e), chloroplast SSU ribosomal protein S8p (S15Ae), chloroplast SSU ribosomal protein S9p (S16e), chloroplast Ribosome_SSU_eukaryotic_and_archaeal SSU ribosomal protein S11e (S17p) SSU ribosomal protein S13e (S15p) SSU ribosomal protein S14e (S11p) SSU ribosomal protein S15Ae (S8p) SSU ribosomal protein S15e (S19p) SSU ribosomal protein S16e (S9p) SSU ribosomal protein S17e SSU ribosomal protein S18e (S13p) SSU ribosomal protein S19e SSU ribosomal protein S20e (S10p) SSU ribosomal protein S23e (S12p) SSU ribosomal protein S24e SSU ribosomal protein S25e SSU ribosomal protein S26e SSU ribosomal protein S27Ae SSU ribosomal protein S27e SSU ribosomal protein S28e SSU ribosomal protein S29e (S14p) SSU ribosomal protein S2e (S5p) SSU ribosomal protein S30e SSU ribosomal protein S3Ae SSU ribosomal protein S3e (S3p) SSU ribosomal protein S4e SSU ribosomal protein S5e (S7p) SSU ribosomal protein S6e SSU ribosomal protein S8e SSU ribosomal protein S9e (S4p) SSU ribosomal protein SAe (S2p) Ribosome_SSU_mitochondrial SSU ribosomal protein MRP1, mitochondrial SSU ribosomal protein MRP10, mitochondrial SSU ribosomal protein MRP13, mitochondrial SSU ribosomal protein PET123, mitochondrial SSU ribosomal protein RSM22, mitochondrial SSU ribosomal protein RSM24, mitochondrial SSU ribosomal protein RSM25, mitochondrial SSU ribosomal protein RSM28, mitochondrial SSU ribosomal protein S10p (S20e), mitochondrial SSU ribosomal protein S11p (S14e), mitochondrial SSU ribosomal protein S12p (S23e), mitochondrial SSU ribosomal protein S13p (S18e), mitochondrial SSU ribosomal protein S14p (S29e), mitochondrial SSU ribosomal protein S15p (S13e), mitochondrial SSU ribosomal protein S16p, mitochondrial SSU ribosomal protein S17p (S11e), mitochondrial SSU ribosomal protein S18p, mitochondrial SSU ribosomal protein S19p (S15e), mitochondrial SSU ribosomal protein S21p, mitochondrial SSU ribosomal protein S22mt, mitochondrial SSU ribosomal protein S23mt, mitochondrial SSU ribosomal protein S24mt, mitochondrial SSU ribosomal protein S25mt, mitochondrial SSU ribosomal protein S26mt, mitochondrial SSU ribosomal protein S27mt, mitochondrial SSU ribosomal protein S28mt, mitochondrial SSU ribosomal protein S29mt, mitochondrial SSU ribosomal protein S2p (SAe), mitochondrial SSU ribosomal protein S30mt, mitochondrial SSU ribosomal protein S31mt, mitochondrial SSU ribosomal protein S33mt, mitochondrial SSU ribosomal protein S34mt, mitochondrial SSU ribosomal protein S35mt, mitochondrial SSU ribosomal protein S3p (S3e), mitochondrial SSU ribosomal protein S4p (S9e), mitochondrial SSU ribosomal protein S5p (S2e), mitochondrial SSU ribosomal protein S6p, mitochondrial SSU ribosomal protein S7p (S5e), mitochondrial SSU ribosomal protein S8p (S15Ae), mitochondrial SSU ribosomal protein S9p (S16e), mitochondrial SSU ribosomal protein VAR1, mitochondrial Ribosome_activity_modulation Ribosomal subunit interface protein Ribosome hibernation protein YfiA Ribosome hibernation protein YhbH Ribosome modulation factor Stationary-phase-induced ribosome-associated protein Ribosome_biogenesis_bacterial 16S rRNA processing protein RimM Dimethyladenosine transferase (EC 2.1.1.-) Inactive homolog of metal-dependent proteases, putative molecular chaperone LSU m3Psi1915 methyltransferase RlmH LSU m5C1962 methyltransferase RlmI RNA pseudouridylate synthase, group 1 Ribonuclease E (EC 3.1.26.12) Ribonuclease M5 (EC 3.1.26.8) Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) Ribosomal protein L11 methyltransferase (EC 2.1.1.-) Ribosomal protein S6 glutaminyl transferase Ribosomal-protein-L7p-serine acetyltransferase Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) Ribosomal-protein-S5p-alanine acetyltransferase Similar to ribosomal large subunit pseudouridine synthase A Similar to ribosomal large subunit pseudouridine synthase A, group 2 Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YhcT type Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type Similar to ribosomal large subunit pseudouridine synthase D, CAC1266-type Similar to ribosomal large subunit pseudouridine synthase D, TTE1780-type hypothetical protein sometimes fused to ribosomal protein S6 glutaminyl transferase tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) Trans-translation_by_stalled_ribosomes Transfer-messenger RNA (tmRNA) involved in trans-translation tmRNA-binding protein SmpB Translation_elongation_factor_G_family Oxytetracycline resistance protein OtrA Ribosome protection-type tetracycline resistance related proteins Ribosome protection-type tetracycline resistance related proteins, group 2 Tetracycline resistance protein TetM Tetracycline resistance protein TetO Tetracycline resistance protein TetP Tetracycline resistance protein TetQ Translation elongation factor 2 Translation elongation factor G Translation elongation factor G Stremptomyces paralog Translation elongation factor G paralog Translation elongation factor G, mitochondrial Translation elongation factor G-related protein Translation_elongation_factors_bacterial Translation elongation factor G Translation elongation factor G paralog Translation elongation factor G-related protein Translation elongation factor LepA Translation elongation factor P Translation elongation factor P-related protein Translation elongation factor Ts Translation elongation factor Tu Translation_elongation_factors_eukaryotic_and_archaeal Eukaryotic peptide chain release factor GTP-binding subunit Eukaryotic peptide chain release factor subunit 1 HBS1 protein Translation elongation factor 1 alpha subunit Translation elongation factor 1 alpha-related protein Translation elongation factor 1 beta subunit Translation elongation factor 1 delta subunit Translation elongation factor 1 gamma subunit Translation elongation factor 2 Translation elongation factor 3 Translation elongation factor P Translation_initiation_factors_bacterial Methionyl-tRNA formyltransferase (EC 2.1.2.9) Ribosome-binding factor A Translation initiation factor 1 Translation initiation factor 2 Translation initiation factor 3 Translation initiation factor 3 related protein Translation initiation factor SUI1-related protein Translation_initiation_factors_eukaryotic_and_archaeal Eukaryotic translation initiation factor 2 alpha subunit Eukaryotic translation initiation factor 2 beta subunit Eukaryotic translation initiation factor 2 gamma subunit Eukaryotic translation initiation factor 5A Eukaryotic translation initiation factor 6 Translation initiation factor 1A Translation initiation factor 2 Translation initiation factor 2B alpha subunit Translation initiation factor 2B alpha/beta/delta-type subunit Translation initiation factor SUI1-related protein Translation_termination_factors_bacterial Hypothetical protein YaeJ with similarity to translation release factor Methionine aminopeptidase (EC 3.4.11.18) Peptide chain release factor 1 Peptide chain release factor 2 Peptide chain release factor 3 Peptide chain release factor homolog Peptide deformylase (EC 3.5.1.88) Peptidyl-tRNA hydrolase (EC 3.1.1.29) Protein with similarity to RtcB Ribosome recycling factor tmRNA-binding protein SmpB Universal_GTPases 50S ribosomal subunit maturation GTPase RbgA (B. subtilis YlqF) COG0536: GTP-binding protein Obg GTP-binding and nucleic acid-binding protein YchF GTP-binding protein EngA GTP-binding protein EngB GTP-binding protein Era GTP-binding protein HflX GTP-binding protein TypA/BipA GTP-binding protein YqeH, required for biogenesis of 30S ribosome subunit GTPase and tRNA-U34 5-formylation enzyme TrmE Probable GTPase related to EngC Ribosome small subunit-stimulated GTPase EngC Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1) Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1) Translation elongation factor 1 alpha subunit Translation elongation factor 2 Translation elongation factor G Translation elongation factor LepA Translation elongation factor Tu Translation initiation factor 2 rRNAs 5S rRNA LSU rRNA SSU rRNA tRNA_aminoacylation,_Ala Alanyl-tRNA synthetase (EC 6.1.1.7) Alanyl-tRNA synthetase domain protein Alanyl-tRNA synthetase family protein Alanyl-tRNA synthetase, amino-terminal half (EC 6.1.1.7) Alanyl-tRNA synthetase, carboxy-terminal half (EC 6.1.1.7) tRNA_aminoacylation,_Arg Arginyl-tRNA synthetase (EC 6.1.1.19) Arginyl-tRNA synthetase related protein 1 Arginyl-tRNA synthetase related protein 2 tRNA_aminoacylation,_Asp_and_Asn Asparaginyl-tRNA synthetase (EC 6.1.1.22) Aspartyl-tRNA synthetase (EC 6.1.1.12) Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) Aspartyl-tRNA(Asn) synthetase (EC 6.1.1.23) tRNA_aminoacylation,_Cys Cysteinyl-tRNA synthetase (EC 6.1.1.16) Cysteinyl-tRNA synthetase paralog 1 Cysteinyl-tRNA synthetase paralog 2 O-phosphoseryl-tRNA(Cys) synthetase O-phosphoseryl-tRNA:Cysteinyl-tRNA synthase Protein clustered with O-phosphoseryl-tRNA(Cys) synthetase domain similar to cysteinyl-tRNA synthetase and MshC tRNA_aminoacylation,_Glu_and_Gln Glutaminyl-tRNA synthetase (EC 6.1.1.18) Glutamyl-tRNA synthetase (EC 6.1.1.17) Glutamyl-tRNA(Gln) amidotransferase asparaginase subunit (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase subunit F (EC 6.3.5.7) Glutamyl-tRNA(Gln) amidotransferase transferase subunit (EC 6.3.5.7) Glutamyl-tRNA(Gln) synthetase (EC 6.1.1.24) tRNA_aminoacylation,_Gly Glycyl-tRNA synthetase (EC 6.1.1.14) Glycyl-tRNA synthetase (EC 6.1.1.14), carboxy-terminal 114 amino acids Glycyl-tRNA synthetase alpha chain (EC 6.1.1.14) Glycyl-tRNA synthetase beta chain (EC 6.1.1.14) tRNA_aminoacylation,_His Histidyl-tRNA synthetase (EC 6.1.1.21) Histidyl-tRNA synthetase related protein 3 Histidyl-tRNA synthetase related protein in Streptococcus pneumoniae Histidyl-tRNA synthetase, archaeal-type paralog (EC 6.1.1.21) tRNA_aminoacylation,_Ile Isoleucyl-tRNA synthetase (EC 6.1.1.5) Isoleucyl-tRNA synthetase related gene in Burkholderia tRNA_aminoacylation,_Leu Leucyl-tRNA synthetase (EC 6.1.1.4) Leucyl-tRNA synthetase-like protein in Burkholderia mallei group tRNA_aminoacylation,_Lys Lysyl-tRNA synthetase (class I) (EC 6.1.1.6) Lysyl-tRNA synthetase (class II) (EC 6.1.1.6) Lysyl-tRNA synthetase (class II) (EC 6.1.1.6), mitochondrial Lysyl-tRNA synthetase (class II) related protein found fused to membrane protein Putative membrane protein found fused to lysyl-tRNA synthetase like protein tRNA_aminoacylation,_Met Methionyl-tRNA synthetase (EC 6.1.1.10) Methionyl-tRNA synthetase, clostridial paralog Methionyl-tRNA synthetase-related protein Methionyl-tRNA synthetase-related protein 2 Structure-specific tRNA-binding protein Structure-specific tRNA-binding protein trbp111 tRNA-binding protein YgjH tRNA_aminoacylation,_Phe Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) Protein with domain from phenylalanyl-tRNA synthetase alpha chain tRNA_aminoacylation,_Pro Prolyl-tRNA synthetase (EC 6.1.1.15) Prolyl-tRNA synthetase related protein Prolyl-tRNA synthetase-related protein 1 tRNA_aminoacylation,_Pyr Pyrrolysyl-tRNA synthetase (EC 6.1.1.26) tRNA_aminoacylation,_Ser Archaeal seryl-tRNA synthetase-related sequence Seryl-tRNA synthetase (EC 6.1.1.11) Seryl-tRNA synthetase (EC 6.1.1.11), archaeal tRNA_aminoacylation,_Thr Threonyl-tRNA synthetase (EC 6.1.1.3) Threonyl-tRNA synthetase fragment Threonyl-tRNA synthetase-related protein tRNA_aminoacylation,_Trp Tryptophanyl-tRNA synthetase (EC 6.1.1.2) tRNA_aminoacylation,_Tyr Tyrosyl-tRNA synthetase (EC 6.1.1.1) tRNA_aminoacylation,_Val Valyl-tRNA synthetase (EC 6.1.1.9) tRNAs tRNA-Ala tRNA-Ala-CGC tRNA-Ala-GGC tRNA-Ala-UGC tRNA-Arg tRNA-Arg-ACG tRNA-Arg-CCG tRNA-Arg-GCG tRNA-Arg-UCU tRNA-Asn tRNA-Asn-GUU tRNA-Asp tRNA-Asp-GUC tRNA-Asx tRNA-Cys tRNA-Cys-GCA tRNA-Gln tRNA-Gln-UUG tRNA-Glu tRNA-Glu-UUC tRNA-Gly tRNA-Gly-CCC tRNA-Gly-GCC tRNA-Gly-UCC tRNA-His tRNA-His-GUG tRNA-Ile tRNA-Ile-GAU tRNA-Leu tRNA-Leu-CAA tRNA-Leu-CAG tRNA-Leu-GAG tRNA-Leu-UAA tRNA-Leu-UAG tRNA-Lys tRNA-Lys-UUU tRNA-Met tRNA-Met-CAU tRNA-Phe tRNA-Phe-GAA tRNA-Pro tRNA-Pro-CGG tRNA-Pro-GGG tRNA-Pro-UGG tRNA-SeC tRNA-Ser tRNA-Ser-CGA tRNA-Ser-GCU tRNA-Ser-GGA tRNA-Ser-UGA tRNA-Thr tRNA-Thr-CGU tRNA-Thr-GGU tRNA-Thr-UGU tRNA-Trp tRNA-Trp-CCA tRNA-Tyr tRNA-Tyr-GUA tRNA-Unknown tRNA-Val tRNA-Val-CAC tRNA-Val-GAC tRNA-Val-UAC 02 Protein degradation Aminopeptidases_(EC_3.4.11.-) Aminopeptidase S (Leu, Val, Phe, Tyr preference) (EC 3.4.11.24) Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15) Cytosol aminopeptidase PepA (EC 3.4.11.1) Membrane alanine aminopeptidase N (EC 3.4.11.2) Peptidase B (EC 3.4.11.23) Xaa-Pro aminopeptidase (EC 3.4.11.9) Dipeptidases_(EC_3.4.13.-) Alpha-aspartyl dipeptidase Peptidase E (EC 3.4.13.21) Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3) Xaa-Pro dipeptidase PepQ (EC 3.4.13.9) Metallocarboxypeptidases_(EC_3.4.17.-) Carboxypeptidase T (EC 3.4.17.18) D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) Glutamate carboxypeptidase (EC 3.4.17.11) Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) Thermostable carboxypeptidase 1 (EC 3.4.17.19) Zinc D-Ala-D-Ala carboxypeptidase (EC 3.4.17.14) Metalloendopeptidases_(EC_3.4.24.-) Bacillolysin, extracellular neutral metalloprotease (EC 3.4.24.28) Glycyl-glycine endopeptidase LytM precursor (EC 3.4.24.75) Microbial collagenase (EC 3.4.24.3) Microbial collagenase, secreted (EC 3.4.24.3) Pseudolysin, extracellular zinc protease (EC 3.4.24.26) Vibriolysin, extracellular zinc protease (EC 3.4.24.25) Omega_peptidases_(EC_3.4.19.-) Acylamino-acid-releasing enzyme (EC 3.4.19.1) Gamma-D-glutamyl-meso-diaminopimelate peptidase (EC 3.4.19.11) Isoaspartyl aminopeptidase (EC 3.4.19.5) Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) Proteasome_archaeal Bacterial proteasome-activating AAA-ATPase (PAN) Prokaryotic ubiquitin-like protein Pup Proteasome subunit alpha (EC 3.4.25.1), archaeal Proteasome subunit alpha (EC 3.4.25.1), bacterial Proteasome subunit beta (EC 3.4.25.1), archaeal Proteasome subunit beta (EC 3.4.25.1), bacterial Proteasome-activating AAA-ATPase (PAN), archaeal Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA' Pup ligase PafA, possible component of postulated heterodimer PafA-PafA' Proteasome_bacterial ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) ATP-dependent hsl protease ATP-binding subunit HslU ATP-dependent protease HslV (EC 3.4.25.-) ATP-dependent protease La (EC 3.4.21.53) LonB Type I ATP-dependent protease La (EC 3.4.21.53) Type I ATP-dependent protease La (EC 3.4.21.53) Type II ATP-dependent protease LonB-like Type I Lon-like protease with PDZ domain Prokaryotic ubiquitin-like protein Pup Site-specific tyrosine recombinase Uncharacterized protein, similar to the N-terminal domain of Lon protease Proteasome_eukaryotic proteasome regulatory subunit Rpn1 proteasome regulatory subunit Rpn10 proteasome regulatory subunit Rpn11 proteasome regulatory subunit Rpn12 proteasome regulatory subunit Rpn13 proteasome regulatory subunit Rpn2 proteasome regulatory subunit Rpn3 proteasome regulatory subunit Rpn4 proteasome regulatory subunit Rpn5 proteasome regulatory subunit Rpn6 proteasome regulatory subunit Rpn7 proteasome regulatory subunit Rpn8 proteasome regulatory subunit Rpn9 proteasome regulatory subunit Rpt1 proteasome regulatory subunit Rpt2 proteasome regulatory subunit Rpt3 proteasome regulatory subunit Rpt4 proteasome regulatory subunit Rpt5 proteasome regulatory subunit Rpt6 proteasome regulatory subunit S5b proteasome regulatory subunit p28 proteasome regulatory subunit p29 proteasome subunit alpha1 (EC 3.4.25.1) proteasome subunit alpha2 (EC 3.4.25.1) proteasome subunit alpha3 (EC 3.4.25.1) proteasome subunit alpha4 (EC 3.4.25.1) proteasome subunit alpha5 (EC 3.4.25.1) proteasome subunit alpha6 (EC 3.4.25.1) proteasome subunit alpha7 (EC 3.4.25.1) proteasome subunit beta1 (EC 3.4.25.1) proteasome subunit beta10 (EC 3.4.25.1) proteasome subunit beta11 (EC 3.4.25.1) proteasome subunit beta2 (EC 3.4.25.1) proteasome subunit beta3 (EC 3.4.25.1) proteasome subunit beta4 (EC 3.4.25.1) proteasome subunit beta5 (EC 3.4.25.1) proteasome subunit beta5b (EC 3.4.25.1) proteasome subunit beta6 (EC 3.4.25.1) proteasome subunit beta7 (EC 3.4.25.1) proteasome subunit beta8 (EC 3.4.25.1) proteasome subunit beta9 (EC 3.4.25.1) Protein_degradation Aminopeptidase C (EC 3.4.22.40) Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific) Arginine-tRNA-protein transferase (EC 2.3.2.8) Asp-X dipeptidase Deblocking aminopeptidase (EC 3.4.11.-) Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5) Isoaspartyl dipeptidase (EC 3.4.19.5) Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) Nondeblocking aminopeptidase YpdE (X-X-[^PR]- specific) Oligopeptidase A (EC 3.4.24.70) Thimet oligopeptidase (EC 3.4.24.15) Proteolysis_in_bacteria,_ATP-dependent ATP-dependent Clp protease ATP-binding subunit ClpA ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent Clp protease adaptor protein ClpS ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) ATP-dependent Clp protease, ATP-binding subunit ClpC ATP-dependent hsl protease ATP-binding subunit HslU ATP-dependent protease HslV (EC 3.4.25.-) ATP-dependent protease La (EC 3.4.21.53) ATP-dependent protease La (EC 3.4.21.53) Type I ATP-dependent protease La (EC 3.4.21.53) Type II ATP-dependent protease domain protein (EC 3.4.21.-) ATPase, AFG1 family ClpB protein ClpXP protease specificity-enhancing factor Nucleotide excision repair protein, with UvrB/UvrC motif Outer membrane stress sensor protease DegQ, serine protease Outer membrane stress sensor protease DegS Putative_TldE-TldD_proteolytic_complex FIG138315: Putative alpha helix protein TldD family protein, Actinobacterial subgroup TldD family protein, Beta/Gamma-proteobacterial subgroup TldD protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038) TldD-domain protein TldE/PmbA family protein, Actinobacterial subgroup TldE/PmbA family protein, Beta/Gamma-proteobacterial subgroup TldE/PmbA protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038) Serine_endopeptidase_(EC_3.4.21.-) Glutamyl endopeptidase precursor (EC 3.4.21.19), blaSE Glutamyl endopeptidase precursor (EC 3.4.21.19), serine proteinase SspA Lysyl endopeptidase (EC 3.4.21.50) Prolyl endopeptidase (EC 3.4.21.26) 02 Protein folding GroEL_GroES Heat shock protein 60 family chaperone GroEL Heat shock protein 60 family co-chaperone GroES Peptidyl-prolyl_cis-trans_isomerase FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8) FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) FKBP-type peptidyl-prolyl cis-trans isomerase fklB (EC 5.2.1.8) FKBP-type peptidyl-prolyl cis-trans isomerase slpA (EC 5.2.1.8) Foldase protein PrsA precursor (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase ppiA precursor (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase ppiB (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase ppiC (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase ppiD (EC 5.2.1.8) Putative parvulin type peptidyl-prolyl isomerase, similarity with PrsA foldase Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) Periplasmic_disulfide_interchange Cytochrome c-type biogenesis protein CcdA (DsbD analog) Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) Periplasmic thiol:disulfide interchange protein DsbA Periplasmic thiol:disulfide interchange protein, DsbA-like Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation Thiol:disulfide interchange protein DsbC Thiol:disulfide interchange protein DsbG precursor Protein_chaperones Chaperone protein DnaJ Chaperone protein DnaK Chaperone protein HscA Chaperone protein HscB Chaperone protein HtpG Chaperone-modulator protein CbpM ClpB protein DnaJ-class molecular chaperone CbpA Heat shock protein GrpE HspR, transcriptional repressor of DnaK operon Thermosome,_archaeal Thermosome subunit 02 Protein processing and modification Inteins Amino-terminal intein-mediated trans-splice Carboxy-terminal intein-mediated trans-splice intein-containing Lipoprotein_Biosynthesis Apolipoprotein N-acyltransferase (EC 2.3.1.-) Lipoprotein signal peptidase (EC 3.4.23.36) Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-) N-linked_Glycosylation_in_Bacteria 4-amino-6-deoxy-N-Acetyl-D-hexosaminyl-(Lipid carrier) acetyltrasferase 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(Lipid carrier) aminotransferase Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-) Alpha-1,4-N-acetylgalactosamine transferase PglH (EC 2.4.1.-) Alpha-1,4-N-acetylgalactosamine transferase PglJ (EC 2.4.1.-) Glycosyltransferase PglI (EC 2.4.1.-) Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) N-linked glycosylation glycosyltransferase PglG Oligosaccharyltransferase PglB (EC 2.4.1.119) Phospholipid-lipopolysaccharide ABC transporter UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) UDP-glucose 4-epimerase (EC 5.1.3.2) Peptide_methionine_sulfoxide_reductase Cytochrome c-type biogenesis protein CcdA homolog, associated with MetSO reductase Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) Thiol:disulfide oxidoreductase associated with MetSO reductase Two-component response regulator yesN, associated with MetSO reductase Two-component sensor kinase yesM (EC 2.7.3.-), associated with MetSO reductase Protein_Acetylation_and_Deacetylation_in_Bacteria Acetate permease ActP (cation/acetate symporter) Acetyl-coenzyme A synthetase (EC 6.2.1.1) NAD-dependent protein deacetylase of SIR2 family Propionate--CoA ligase (EC 6.2.1.17) Protein acetyltransferase Ribosomal_protein_S12p_Asp_methylthiotransferase MiaB family protein, possibly involved in tRNA or rRNA modification Ribosomal protein S12p Asp88 (E. coli) methylthiotransferase SSU ribosomal protein S12p (S23e) tRNA-i(6)A37 methylthiotransferase Ribosomal_protein_S5p_acylation Ribosomal-protein-S5p-alanine acetyltransferase SSU ribosomal protein S5p (S2e) Signal_peptidase Lipoprotein signal peptidase (EC 3.4.23.36) Signal peptidase I (EC 3.4.21.89) Signal peptidase, type IV - prepilin/preflagellin Ubiquitin-like_archaeal_modifier_proteins_(SAMPs) HesA/MoeB/ThiF family protein, possibly E1-enzyme activating SAMPs for protein conjugation Ubiquitin-like small archaeal modifier protein SAMP1 Ubiquitin-like small archaeal modifier protein SAMP2 02 Secretion Protein_secretion_by_ABC-type_exporters ABC exporter for hemopore HasA, ATP-binding component HasD ABC exporter for hemopore HasA, membrane fusion protein (MFP) family component HasE ABC exporter for hemopore HasA, outer membrane component HasF ABC-type protease exporter, ATP-binding component PrtD/AprD ABC-type protease exporter, membrane fusion protein (MFP) family component PrtE/AprE ABC-type protease exporter, outer membrane component PrtF/AprF Alkaline proteinase inhibitor precursor Hemophore HasA Hemophore HasA outer membrane receptor HasR Probable transmembrane heme sensor Putative tonB protein Secreted alkaline metalloproteinase (EC 3.4.24.-), PrtA/B/C/G homolog 02 Selenoproteins Glycine_reductase,_sarcosine_reductase_and_betaine_reductase Betaine reductase component B alpha subunit (EC 1.21.4.4) Betaine reductase component B beta subunit (EC 1.21.4.4) Glycine reductase component B alpha subunit (EC 1.21.4.2) Glycine reductase component B beta subunit (EC 1.21.4.2) Glycine reductase component B gamma subunit (EC 1.21.4.2) Glycine/sarcosine/betaine reductase component C chain 1 Glycine/sarcosine/betaine reductase component C chain 2 Glycine/sarcosine/betaine reductase protein A Sarcosine reductase component B alpha subunit (EC 1.21.4.3) Sarcosine reductase component B beta subunit (EC 1.21.4.3) Thioredoxin Thioredoxin reductase (EC 1.8.1.9) Selenocysteine_metabolism L-seryl-tRNA(Sec) kinase L-seryl-tRNA(Sec) selenium transferase (EC 2.9.1.1) O-phosphoseryl-tRNA(Sec) selenium transferase Selenide,water dikinase (EC 2.7.9.3) Selenocysteine-specific translation elongation factor Selenophosphate-dependent tRNA 2-selenouridine synthase UPF0425 pyridoxal phosphate-dependent protein MJ0158 selenocysteine-containing Selenoprotein_O Selenoprotein O and cysteine-containing homologs 01 RNA Metabolism 02 RNA processing and modification ATP-dependent_RNA_helicases,_bacterial ATP-dependent RNA helicase Atu1833 ATP-dependent RNA helicase BA2475 ATP-dependent RNA helicase Bcep18194_A5658 ATP-dependent RNA helicase DbpA ATP-dependent RNA helicase NGO0650 ATP-dependent RNA helicase PA3950 ATP-dependent RNA helicase RhlB ATP-dependent RNA helicase RhlE ATP-dependent RNA helicase SO1501 ATP-dependent RNA helicase SrmB ATP-dependent RNA helicase VC1407 ATP-dependent RNA helicase VCA0061 ATP-dependent RNA helicase VCA0768 ATP-dependent RNA helicase VCA0990 ATP-dependent RNA helicase VF1437 ATP-dependent RNA helicase VVA0939 ATP-dependent RNA helicase YfmL ATP-dependent RNA helicase YqfR ATP-dependent RNA helicase YxiN Cold-shock DEAD-box protein A Exosome Exosome complex RNA binding Csl4 Exosome complex RNA binding RRP40 Exosome complex exonuclease MTR3 (EC 3.1.13.-) Exosome complex exonuclease RRP4 Exosome complex exonuclease RRP41 (EC 3.1.13.-) Exosome complex exonuclease RRP42 (EC 3.1.13.-) Exosome complex exonuclease RRP43 (EC 3.1.13.-) Exosome complex exonuclease RRP45 (EC 3.1.13.-) Exosome complex exonuclease RRP46 (EC 3.1.13.-) Exosome complex exonuclease RRP6 (EC 3.1.13.-) Methylthiotransferases MiaB family protein, possibly involved in tRNA or rRNA modification Ribosomal protein S12p Asp88 (E. coli) methylthiotransferase tRNA N6-threonylcarbamoyladenosine 2-methylthiotransferase (putative) tRNA-i(6)A37 methylthiotransferase Polyadenylation_bacterial Poly(A) polymerase (EC 2.7.7.19) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) RNA-binding protein Hfq tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25) tRNA nucleotidyltransferase, A-adding (EC 2.7.7.25) tRNA nucleotidyltransferase, CC-adding (EC 2.7.7.21) Queuosine-Archaeosine_Biosynthesis COG2047: Uncharacterized protein (ATP-grasp superfamily) Dihydroneopterin triphosphate pyrophosphohydolase Dihydroneopterin triphosphate pyrophosphohydolase type 2 GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase I (EC 3.5.4.16) type 2 Glutamine amidotransferases class-II (GATase) Hydrolase (HAD superfamily) in cluster with DUF1447 Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1) NADPH dependent preQ0 reductase NADPH dependent preQ0 reductase-like Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) Peptidyl-prolyl cis-trans isomerase ppiB (EC 5.2.1.8) Permease of the drug/metabolite transporter (DMT) superfamily Putative preQ0 transporter Queuosine Biosynthesis QueC ATPase Queuosine Biosynthesis QueE Radical SAM Queuosine biosynthesis QueD, PTPS-I Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) Substrate-specific component QueT (COG4708) of predicted queuosine-regulated ECF transporter Substrate-specific component STY3230 of queuosine-regulated ECF transporter archaeosine tRNA-ribosyltransferase (EC 2.4.2.-) type 1 archaeosine tRNA-ribosyltransferase (EC 2.4.2.-) type 1 like archaeosine tRNA-ribosyltransferase (EC 2.4.2.-) type 2 archaeosine tRNA-ribosyltransferase (EC 2.4.2.-) type 5 glutamyl-Q-tRNA synthetase preQ1-regulated inosine-uridine nucleoside hydrolase (EC 3.2.2.1) tRNA-guanine transglycosylase (EC 2.4.2.29) RNA_3'-terminal_phosphate_cyclase Protein RtcB Protein with similarity to RtcB RNA 3'-terminal phosphate cyclase (EC 6.5.1.4) Transcriptional regulatory protein RtcR RNA_processing_and_degradation,_bacterial 3'-to-5' exoribonuclease RNase R 3'-to-5' oligoribonuclease (orn) 3'-to-5' oligoribonuclease B, Bacillus type Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) Exoribonuclease II (EC 3.1.13.1) FIG146085: 3'-to-5' oligoribonuclease A, Bacillus type Ribonuclease E (EC 3.1.26.12) Ribonuclease E inhibitor RraA Ribonuclease E inhibitor RraB Ribonuclease I precursor (EC 3.1.27.6) Ribonuclease III (EC 3.1.26.3) RNA_processing_orphans 2'-5' RNA ligase 2H phosphoesterase superfamily protein BC2899 2H phosphoesterase superfamily protein Bsu1186 (yjcG) RNA_pseudouridine_syntheses Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase F (EC 4.2.1.70) Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA pseudouridine synthase B (EC 4.2.1.70) tRNA pseudouridine synthase C (EC 4.2.1.70) Ribonuclease_H Protein often found in Actinomycetes clustered with signal peptidase and/or RNaseHII Ribonuclease HI (EC 3.1.26.4) Ribonuclease HI, Vibrio paralog Ribonuclease HI-related protein Ribonuclease HI-related protein 2 Ribonuclease HI-related protein 3 Ribonuclease HII (EC 3.1.26.4) Ribonuclease HIII (EC 3.1.26.4) hypothetical protein ssl1918 Ribonuclease_P_archaeal_and_eukaryal Ribonuclease P protein component 1 (EC 3.1.26.5) Ribonuclease P protein component 2 (EC 3.1.26.5) Ribonuclease P protein component 3 (EC 3.1.26.5) Ribonuclease P protein component 4 (EC 3.1.26.5) Ribosome_biogenesis_archaeal Fibrillarin rRNA biogenesis protein Nop5/Nop56 Spliceosome Pre-mRNA splicing factor PRP1 Pre-mRNA splicing factor PRP6 Pre-mRNA splicing factor PRP8 U4/U6 small nuclear ribonucleoprotein component PRP3 Wyeosine-MimG_Biosynthesis Fe-S OXIDOREDUCTASE (1.8.-.-) Wyeosine biosynthesis Hypothetical ATP-binding protein, containing DUF265 domain Iron-sulfur cluster assembly scaffold protein IscU PAB2272 methyltransferase homolog Thioredoxin reductase (EC 1.8.1.9) Uncharacterized protein conserved in archaea (DUF531) tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) tRNA methylase Trm12p Wyeosine biosynthesis tRNA methylase YGL050w homolog Wyeosine biosynthesis tRNA methylase YGL050w homolog Wyeosine biosynthesis type 2 tRNA methylase Yol141w homolog Wyeosine biosynthesis YrdC-YciO COG0613, Predicted metal-dependent phosphoesterases (PHP family) Inactive homolog of metal-dependent proteases, putative molecular chaperone Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase YciO family YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA eukaryotic_rRNA_modification_and_related_functions Collagen alpha 1(I) chain precursor SSU ribosomal protein S14e (S11p) rRNA_modification_Archaea C*N330 1404 COG2106 Methylase COG3269, Predicted RNA-binding protein, contains TRAM domain Dimethyladenosine transferase (EC 2.1.1.-) Fibrillarin Gm1909 Gm2553 LSU ribosomal protein L7Ae Predicted N6-adenine-specific RNA methylase containing THUMP domain Predicted RNA methylase COG2263 Predicted RNA-binding protein COG1491 Predicted Zn-ribbon RNA-binding protein with a function in translation Putative RNA-binding protein COG1094 Ribosomal RNA large subunit methyltransferase J (EC 2.1.1.-) Ribosome biogenesis protein Nop10 conserved protein with predicted RNA binding PUA domain gar1 - like small nucleolar rnp m1A571 rRNA biogenesis protein Nop5/Nop56 tRNA pseudouridine 55 synthase (EC 4.2.1.70) tRNA:Cm32/Um32 methyltransferase rRNA_modification_Bacteria 23S rRNA (Uracil-5-) -methyltransferase rumA (EC 2.1.1.-) 23S rRNA (Uracil-5-) -methyltransferase rumB (EC 2.1.1.-) 23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-) 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) Dimethyladenosine transferase (EC 2.1.1.-) LSU m3Psi1915 methyltransferase RlmH Pseudouridine synthase family protein RNA binding methyltransferase FtsJ like Ribosomal RNA large subunit methyltransferase A (EC 2.1.1.51) Ribosomal RNA large subunit methyltransferase E (EC 2.1.1.-) Ribosomal RNA large subunit methyltransferase F (EC 2.1.1.51) Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase C (EC 2.1.1.52) Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase F (EC 2.1.1.-) Ribosomal RNA small subunit methyltransferase G (EC 2.1.1.-) Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) Ribosomal large subunit pseudouridine synthase E (EC 5.4.99.-) Ribosomal large subunit pseudouridine synthase F (EC 4.2.1.70) Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) RsuA-like Unknown Cm2498 Unknown hU2449 Unknown m4Cm1402 A Unknown m4Cm1402 B Unknown methyltransferase Psi1915 Unknown methyltransferase m5C1962 Unknown methyltransferase m6A2030 Unknown methyltransferase m7G2069 Unknown methyltransferase mm2G2445 Unknownm2G1616 s2C2501 tRNA:m(5)U-54 MTase gid tRNA_modification_Archaea 5-carboxymethyl uridine and 5-carboxymethyl 2-thiouridine methyltransferase Alanyl-tRNA synthetase domain protein Archease Asparaginyl-tRNA synthetase (EC 6.1.1.22) COG1180: Radical SAM, Pyruvate-formate lyase-activating enzyme like COG1355, Predicted dioxygenase COG1720: Uncharacterized conserved protein COG2078: Uncharacterized ACR COG3269, Predicted RNA-binding protein, contains TRAM domain Cysteine desulfurase (EC 2.8.1.7) Cysteine desulfurase (EC 2.8.1.7), IscS subfamily Cysteine desulfurase (EC 2.8.1.7), NifS subfamily Cysteine desulfurase (EC 2.8.1.7), SufS subfamily Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA GTP-binding protein Era Hypothetical ATP-binding protein, containing DUF265 domain Iron-sulfur cluster assembly scaffold protein IscU Methylthioadenosine deaminase PUA-PAPS reductase like fusion Predicted N6-adenine-specific RNA methylase containing THUMP domain Predicted P-loop ATPase fused to an acetyltransferase COG1444 Predicted methyltransferase, DUF43 family Protein RtcB Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Rhodanese-like domain protein Thiamine biosynthesis protein thiI TilS-like 3 TtuB YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA archaeal ATPase, fused to C-terminal DUF234 domain archaeosine tRNA-ribosyltransferase (EC 2.4.2.-) type 1 tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) tRNA (Uracil54-C5-)-methyltransferase (EC 2.1.1.35) tRNA (adenine57/58-N1)-methyltransferase (EC 2.1.1.36) tRNA and rRNA cytosine-C5-methylase Type 1 tRNA dihydrouridine synthase B (EC 1.-.-.-) tRNA m5C48-49 methylase tRNA pseudouridine 13 synthase (EC 4.2.1.-) tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA(Cytosine32)-2-thiocytidine synthetase tRNA(U54)-2-thioribothymidine synthetase tRNA-i(6)A37 methylthiotransferase tRNA/RNA cytosine-C5-methylase (EC 2.1.1.-) tRNA:Cm32/Um32 methyltransferase tRNA_modification_Bacteria 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC Believed to be involved in assembly of Fe-S clusters COG0613, Predicted metal-dependent phosphoesterases (PHP family) Chaperone protein HscA Chaperone protein HscB Cysteine desulfurase (EC 2.8.1.7) Cysteine desulfurase (EC 2.8.1.7), IscS subfamily Cysteine desulfurase (EC 2.8.1.7), SufS subfamily Cytidine deaminase (EC 3.5.4.5) FIG004453: protein YceG like FIG137478: Hypothetical protein Ferredoxin, 2Fe-2S GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTPase and tRNA-U34 5-formylation enzyme TrmE Iojap protein Iron binding protein IscA for iron-sulfur cluster assembly Iron-sulfur cluster assembly ATPase protein SufC Iron-sulfur cluster assembly protein SufB Iron-sulfur cluster assembly protein SufD Iron-sulfur cluster assembly scaffold protein IscU Iron-sulfur cluster assembly scaffold protein IscU/NifU-like LSU m3Psi1915 methyltransferase RlmH NADPH dependent preQ0 reductase Predicted P-loop ATPase fused to an acetyltransferase COG1444 Putative tRNA-m1A22 methylase Queuosine Biosynthesis QueC ATPase Queuosine Biosynthesis QueE Radical SAM Queuosine biosynthesis QueD, PTPS-I RNA binding methyltransferase FtsJ like Rhodanese-related sulfurtransferases Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) Selenide,water dikinase (EC 2.7.9.3) Selenophosphate-dependent tRNA 2-selenouridine synthase Thiamine biosynthesis protein thiI YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA glutamyl-Q-tRNA synthetase hypothetical tRNA/rRNA methyltransferase yfiF [EC:2.1.1.-] tRNA (5-methoxyuridine) 34 synthase tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) tRNA (Guanosine18-2'-O-) -methyltransferase (EC 2.1.1.34) tRNA (Uracil54-C5-)-methyltransferase (EC 2.1.1.35) tRNA (cytosine34-2'-O-)-methyltransferase (EC 2.1.1.-) tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase tRNA 5-methylaminomethyl-2-thiouridine synthase TusA tRNA 5-methylaminomethyl-2-thiouridine synthase TusB tRNA 5-methylaminomethyl-2-thiouridine synthase TusC tRNA 5-methylaminomethyl-2-thiouridine synthase TusD tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) tRNA dihydrouridine synthase A (EC 1.-.-.-) tRNA dihydrouridine synthase B (EC 1.-.-.-) tRNA pseudouridine 13 synthase (EC 4.2.1.-) tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA pseudouridine synthase B (EC 4.2.1.70) tRNA pseudouridine synthase C (EC 4.2.1.70) tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA tRNA(Cytosine32)-2-thiocytidine synthetase tRNA(Ile)-lysidine synthetase tRNA-(ms[2]io[6]A)-hydroxylase (EC 1.-.-.-) tRNA-dihydrouridine synthase C (EC 1.-.-.-) tRNA-guanine transglycosylase (EC 2.4.2.29) tRNA-i(6)A37 methylthiotransferase tRNA-specific adenosine-34 deaminase (EC 3.5.4.-) tRNA:Cm32/Um32 methyltransferase tRNA:m(5)U-54 MTase gid tRNA_modification_yeast_cytoplasmic Am4 Cm4 Missing Cysteine desulfurase (EC 2.8.1.7) Ncs2p involved in thiolation of mcm5Us4 in tRNA Predicted P-loop ATPase fused to an acetyltransferase COG1444 Pseudouridylate synthase 6 (EC 5.4.99.-) responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31 Pseudouridylate synthase 8 (EC 5.4.99.-) responsible for modification of cytoplasmic tRNAs at position 32 Sua5 YciO YrdC YwlC family protein Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs Urm1p Ubiquitin like protein involve in thiolation of mcm5Us4 in tRNA histone acetyltransferase, ELP3 family m3C32 missing n-type ATP pyrophosphatase superfamily / TilS and TtcA-like tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) tRNA (Guanosine18-2'-O-) -methyltransferase (EC 2.1.1.34) tRNA (Uracil54-C5-)-methyltransferase (EC 2.1.1.35) tRNA (adenine58-N1-)-methylase subunit Gcd10p tRNA (adenine58-N1-)-methylase subunit Gcd14p (EC 2.1.1.36) tRNA (cm5uracil34-C5-)-methyltranferase (EC 2.1.1.-) tRNA (cytosine-5-)-methyltransferase NCL1 (EC 2.1.1.29) (tRNA methyltransferase 4) (Multisite-specific tRNA:m5C-methyltransferase) tRNA (cytosine32/34-2'-O-)-methyltransferase (EC 2.1.1.-) tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (tRNA(m7G46)-methyltransferase) tRNA (guanine10-N2-)-methyltransferase (EC 2.1.1.-) tRNA (guanine46-N7-)-methyltransferase accessory protein tRNA (guanine9-N1-)-methyltransferase (EC 2.1.1.-) tRNA A64-2'-O-ribosylphosphate transferase (EC 2.4.2.-) (Initiator tRNA phosphoribosyl-transferase) tRNA N2,N2-dimethyl(Guanine26-N2)-methyltransferase (EC 2.1.1.32) tRNA Um(44) 2'-O-methyltransferase (Trm44) tRNA acetyltransferase TAN1 (EC 2.3.-.-) tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) tRNA pseudouridine 13 synthase (EC 4.2.1.-) tRNA pseudouridine 55 synthase (EC 4.2.1.70) tRNA pseudouridine synthase 1 (EC 5.4.99.-) introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA specific adenosine-34 deaminase subunit Tad2p tRNA specific adenosine-34 deaminase subunit Tad3p tRNA specific adenosine-37 deaminase (EC 3.5.4.-) Tad1p tRNA-dihydrouridine synthase 1 (EC 1.-.-.-) modifies uridine residues at position 16 and 17 of cytoplasmic tRNAs tRNA-dihydrouridine synthase 2 (EC 1.-.-.-) modifies uridine residues at position 20 of cytoplasmic tRNAs tRNA-dihydrouridine synthase 3 (EC 1.-.-.-) modifies uridine residues at position 47 of cytoplasmic tRNAs tRNA-dihydrouridine synthase 4 (EC 1.-.-.-) modifies uridine residues at position 20A and 20B of cytoplasmic tRNAs tRNA_modification_yeast_mitochondrial GTPase and tRNA-U34 5-formylation enzyme TrmE Pseudouridylate synthase 6 (EC 5.4.99.-) responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31 Pseudouridylate synthase 9 (EC 5.4.99.-) responsible for modification ofmitochondrial tRNAs at position 32 Sua5 YciO YrdC YwlC family protein tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) tRNA (Guanine37-N1) -methyltransferase (EC 2.1.1.31) tRNA (Uracil54-C5-)-methyltransferase (EC 2.1.1.35) tRNA N2,N2-dimethyl(Guanine26-N2)-methyltransferase (EC 2.1.1.32) tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) tRNA pseudouridine 55 synthase (EC 4.2.1.70) tRNA pseudouridine synthase 2 (EC 5.4.99.-) modifies position27/28 in mitochondrial tRNA tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA tRNA-dihydrouridine synthase 1 (EC 1.-.-.-) modifies uridine residues at position 16 and 17 of cytoplasmic tRNAs tRNA-dihydrouridine synthase 2 (EC 1.-.-.-) modifies uridine residues at position 20 of cytoplasmic tRNAs tRNA_nucleotidyltransferase tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25) tRNA nucleotidyltransferase related protein MMP0420 tRNA nucleotidyltransferase, A-adding (EC 2.7.7.25) tRNA nucleotidyltransferase, CC-adding (EC 2.7.7.21) tRNA nucleotidyltransferase, archaeal type (EC 2.7.7.21) (EC 2.7.7.25) tRNA_processing 5-carboxymethyl uridine and 5-carboxymethyl 2-thiouridine methyltransferase Ribonuclease BN (EC 3.1.-.-) Ribonuclease D (EC 3.1.26.3) Ribonuclease P protein component (EC 3.1.26.5) Ribonuclease PH (EC 2.7.7.56) Ribonuclease T (EC 3.1.13.-) Ribonuclease Z (EC 3.1.26.11) tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8) tRNA pseudouridine 13 synthase (EC 4.2.1.-) tRNA pseudouridine 55 synthase (EC 4.2.1.70) tRNA pseudouridine synthase A (EC 4.2.1.70) tRNA pseudouridine synthase B (EC 4.2.1.70) tRNA(Ile)-lysidine synthetase tRNA-i(6)A37 methylthiotransferase tRNA-specific adenosine-34 deaminase (EC 3.5.4.-) tRNAHis-5'-guanylyltransferase tRNA_splicing ADP-ribose 1"-phosphate phophatase RNA:NAD 2'-phosphotransferase tRNA-intron endonuclease (EC 3.1.27.9) 02 Transcription RNA_polymerase_I DNA-directed RNA polymerase I 13.7 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase I 34 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase I 36 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase I 49 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) DNA-directed RNA polymerase I second largest subunit (EC 2.7.7.6) DNA-directed RNA polymerases I and III 16 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I and III 40 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 15 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide (EC 2.7.7.6) RNA_polymerase_II DNA-directed RNA polymerase II 13.2 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase II 13.3 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase II 19 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase II 32 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase II 45 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) DNA-directed RNA polymerase II second largest subunit (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 15 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide (EC 2.7.7.6) RNA_polymerase_III DNA-directed RNA polymerase III 12.5 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 17 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 25 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 31 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 36 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 37/80 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 47 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III 74 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) DNA-directed RNA polymerase III second largest subunit (EC 2.7.7.6) DNA-directed RNA polymerases I and III 16 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I and III 40 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 15 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide (EC 2.7.7.6) DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide (EC 2.7.7.6) RNA_polymerase_III_initiation_factors RNA polymerase III transcription initiation factor (TFIIIC) 131 kDa subunit RNA polymerase III transcription initiation factor (TFIIIC) 138 kDa subunit RNA polymerase III transcription initiation factor (TFIIIC) 55 kDa subunit RNA polymerase III transcription initiation factor (TFIIIC) 60 kDa subunit RNA polymerase III transcription initiation factor (TFIIIC) 91 kDa subunit RNA polymerase III transcription initiation factor (TFIIIC) 95 kDa subunit RNA polymerase III transcription initiation factor B'' RNA polymerase III transcription initiation factor BRF2 TATA-box binding protein Transcription initiation factor IIIA Transcription initiation factor IIIB 70 kDa subunit RNA_polymerase_II_initiation_factors CDK-activating kinase assembly factor MAT1 TATA-box binding protein Transcription initiation factor IIA large subunit Transcription initiation factor IIA small chain Transcription initiation factor IIB Transcription initiation factor IID 145 kDa subunit Transcription initiation factor IID 150 kD subunit Transcription initiation factor IID 23 kDa subunit Transcription initiation factor IID 60 kDa subunit Transcription initiation factor IID 90 kDa subunit Transcription initiation factor IIE alpha subunit Transcription initiation factor IIE beta subunit Transcription initiation factor IIF alpha subunit Transcription initiation factor IIF beta subunit Transcription initiation factor IIH cyclin-dependent kinase 7 Transcription initiation factor IIH p34 subunit Transcription initiation factor IIH p44 subunit Transcription initiation factor IIH p52 subunit Transcription initiation factor IIH p80 subunit Transcription initiation factor IIH p90 subunit RNA_polymerase_archaeal DNA-directed RNA polymerase subunit A (EC 2.7.7.6) DNA-directed RNA polymerase subunit A' (EC 2.7.7.6) DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6) DNA-directed RNA polymerase subunit B (EC 2.7.7.6) DNA-directed RNA polymerase subunit B' (EC 2.7.7.6) DNA-directed RNA polymerase subunit B'' (EC 2.7.7.6) DNA-directed RNA polymerase subunit D (EC 2.7.7.6) DNA-directed RNA polymerase subunit E' (EC 2.7.7.6) DNA-directed RNA polymerase subunit E'' DNA-directed RNA polymerase subunit F (EC 2.7.7.6) DNA-directed RNA polymerase subunit G (EC 2.7.7.6) DNA-directed RNA polymerase subunit H (EC 2.7.7.6) DNA-directed RNA polymerase subunit K (EC 2.7.7.6) DNA-directed RNA polymerase subunit L (EC 2.7.7.6) DNA-directed RNA polymerase subunit N (EC 2.7.7.6) DNA-directed RNA polymerase subunit P (EC 2.7.7.6) DNA-directed RNA polymerase subunit Rpo13 (EC 2.7.7.6) RNA_polymerase_archaeal_initiation_factors Archaeal transcription factor E TATA-box binding protein Transcription initiation factor B Transcription initiation factor B-related protein Zinc finger, TFIIB-type domain protein RNA_polymerase_bacterial DNA-directed RNA polymerase alpha subunit (EC 2.7.7.6) DNA-directed RNA polymerase alpha subunit domain DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6) DNA-directed RNA polymerase delta (= beta'') subunit (EC 2.7.7.6) DNA-directed RNA polymerase delta subunit (EC 2.7.7.6) DNA-directed RNA polymerase gamma subunit (EC 2.7.7.6) DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) RNA_polymerase_chloroplast DNA-directed RNA polymerase alpha subunit (EC 2.7.7.6), chloroplast DNA-directed RNA polymerase beta subunit (EC 2.7.7.6), chloroplast DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6), chloroplast DNA-directed RNA polymerase delta (= beta'') subunit (EC 2.7.7.6), chloroplast DNA-directed RNA polymerase gamma subunit (EC 2.7.7.6), chloroplast DNA-directed RNA polymerase omega subunit (EC 2.7.7.6), chloroplast Rrf2_family_transcriptional_regulators Hmc operon transcriptional regulator Rrf2 Iron-responsive repressor RirA Iron-sulfur cluster regulator IscR Nitrite-sensitive transcriptional repressor NsrR Predicted transcriptional regulator of 4-carboxymuconolactone decarboxylase, Rrf2 family Predicted transcriptional regulator of NADH dehydrogenase, Rrf2 family Predicted transcriptional regulator of cysteine synthase, Rrf2 family Predicted transcriptional regulator of sulfate adenylyltransferase, Rrf2 family Predicted transcriptional regulator of sulfate transport, Rrf2 family Rrf2 family transcriptional regulator Rrf2 family transcriptional regulator, group III Transcription_elongation_factors,_archaeal NusA protein homolog 2, archaeal NusA protein homolog, archaeal Putative transcription antitermination protein NusG Transcription factor S Transcription factor S-related protein 1 Transcription factor S-related protein 2 Transcription factor S-related protein 3 Transcription_factors_bacterial Anti-cleavage anti-GreA transcription factor Gfh1 COG0779: clustered with transcription termination protein NusA COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination Regulator of nucleoside diphosphate kinase Rho-specific inhibitor of transcription termination (YaeO) Transcription antitermination protein NusG Transcription antitermination protein UpdY Transcription elongation factor GreA Transcription elongation factor GreB Transcription elongation factor GreB-related protein Transcription termination factor Rho Transcription termination protein NusA Transcription termination protein NusB Transcription-repair coupling factor Transcriptional activator RfaH ribosomal protein L7Ae family protein Transcription_factors_cyanobacterial_RpoD-like_sigma_factors Cyanobacteria-specific RpoD-like sigma factor, type-1 Cyanobacteria-specific RpoD-like sigma factor, type-11 Cyanobacteria-specific RpoD-like sigma factor, type-12 Cyanobacteria-specific RpoD-like sigma factor, type-13 Cyanobacteria-specific RpoD-like sigma factor, type-14 Cyanobacteria-specific RpoD-like sigma factor, type-2 Cyanobacteria-specific RpoD-like sigma factor, type-3 Cyanobacteria-specific RpoD-like sigma factor, type-4 Cyanobacteria-specific RpoD-like sigma factor, type-5 Cyanobacteria-specific RpoD-like sigma factor, type-6 Cyanobacteria-specific RpoD-like sigma factor, type-7 Cyanobacteria-specific RpoD-like sigma factor, type-9 RNA polymerase sigma factor RpoD Transcription_initiation,_bacterial_sigma_factors RNA polymerase heat shock sigma factor SigI RNA polymerase principal sigma factor HrdA RNA polymerase principal sigma factor HrdC RNA polymerase principal sigma factor HrdD RNA polymerase sigma factor RpoD RNA polymerase sigma factor RpoE RNA polymerase sigma factor RpoH RNA polymerase sigma factor RpoH-related protein RNA polymerase sigma factor RpoH-related protein RpoH2 RNA polymerase sigma factor RpoH-related protein RpoH3 RNA polymerase sigma factor RpoS RNA polymerase sigma factor SigB RNA polymerase sigma factor SigV RNA polymerase sigma factor SigW RNA polymerase sigma factor SigZ RNA polymerase sigma factor for flagellar operon RNA polymerase sigma-54 factor RpoN RNA polymerase sigma-70 factor RNA polymerase sporulation specific sigma factor SigE RNA polymerase sporulation specific sigma factor SigF RNA polymerase sporulation specific sigma factor SigG RNA polymerase sporulation specific sigma factor SigH RNA polymerase sporulation specific sigma factor SigK Serine protease precursor MucD/AlgY associated with sigma factor RpoE Sigma factor RpoE negative regulatory protein RseA Sigma factor RpoE negative regulatory protein RseB precursor Sigma factor RpoE regulatory protein RseC 02 Group_II_intron-associated_genes Retron-type reverse transcriptase 01 Regulation and Cell signaling 02 Programmed Cell Death and Toxin-antitoxin Systems A_toxin-antitoxin_module_cotranscribed_with_DinB Antitoxin YafN Toxin YafO Uncharacterized acetyltransferase YafP (EC 2.3.1.-) Bacterial_Caspases Polysaccharide deacetylase, caspase activity Fratricide_in_Streptococcus Cell wall-associated murein hydrolase LytA Cell wall-associated murein hydrolase LytC Choline binding protein D Immunity factor CibC Immunity factor ComM Two-peptide bacteriocin peptide CibA Two-peptide bacteriocin peptide CibB MazEF_toxin-antitoxing_(programmed_cell_death)_system Programmed cell death antitoxin ChpS Programmed cell death antitoxin MazE Programmed cell death antitoxin PemI Programmed cell death antitoxin YdcD Programmed cell death toxin ChpB Programmed cell death toxin MazF Programmed cell death toxin PemK Programmed cell death toxin YdcE Murein_hydrolase_regulation_and_cell_death Antiholin-like protein LrgA Autolysis histidine kinase LytS Autolysis response regulater LytR CidA-associated membrane protein CidB Cytidine deaminase (EC 3.5.4.5) Holin associated hypothetical protein Holin associated membrane protein 1 Holin associated membrane protein 2 Holin-like protein 1 Holin-like protein 2 Holin-like protein CidA LrgA-associated membrane protein LrgB LysR family regulatory protein CidR Preprotein translocase subunit SecG (TC 3.A.5.1.1) Pyruvate oxidase, CidC S-layer protein EA1 S-layer protein Sap tRNA-dihydrouridine synthase C (EC 1.-.-.-) Phd-Doc,_YdcE-YdcD_toxin-antitoxin_(programmed_cell_death)_systems Death on curing protein, Doc toxin Prevent host death protein, Phd antitoxin Programmed cell death antitoxin MazE like Programmed cell death antitoxin YdcD Programmed cell death toxin MazF like Programmed cell death toxin YdcE Toxin-antitoxin_replicon_stabilization_systems RelB protein (antitoxin to RelE) RelE antibacterial toxin protein SMT0608 replicon stabilization toxin SMT0609 replicon stabilization protein (antitoxin to SMT0608) StbD replicon stabilization protein (antitoxin to StbE) StbE replicon stabilization toxin TTE0858 replicon stabilization protein (antitoxin to TTE0859) TTE0859 replicon stabilization toxin Toxin-antitoxin_systems_(other_than_RelBE_and_MazEF) Antitoxin YgiT CcdA protein (antitoxin to CcdB) CcdB toxin protein DNA-damage-inducible protein J HigA protein (antitoxin to HigB) HigB toxin protein ParD protein (antitoxin to ParE) ParE toxin protein Toxin mRNA interferase YgiU VapB protein (antitoxin to VapC) VapC toxin protein YafQ toxin protein YafW protein (antitoxin to YkfI) YeeU protein (antitoxin to YeeV) YeeV toxin protein YefM protein (antitoxin to YoeB) YfjZ protein (antitoxin to YpjF) YkfI toxin protein YoeB toxin protein YpjF toxin protein 02 Proteolytic pathway Coagulation_cascade Alpha-1-peptidase inhibitor, protease inhibitor I04.001 Alpha-2-macroglobulin, protease inhibitor I39.001 Antithrombin III, protease inhibitor I04.018 Carboxypeptidase U, proteinase M14.009 Coagulation factor IXa, protease S01.214 Coagulation factor V Coagulation factor VIII Coagulation factor VIIa, protease S01.215 Coagulation factor XIII, protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) Coagulation factor XIIa, protease S01.211 Coagulation factor XIa, protease S01.213 Coagulation factor Xa, protease S01.216 Fibrinogen alpha chain Heparin cofactor II, protease inhibitor I04.019 Plasmin, protease S01.233 Plasminogen activator inhibitor-1, protease inhibitor I04.020 Protein C, protease S01.218 Proteinase activated receptor 1 Serpin A5, protease inhibitor I04.004 Thrombin, protease S01.217 Thrombomodulin Tissue factor Tissue factor pathway inhibitor-1, protease inhibitor I02.012 Vitamin K-dependent protein S Von Willebrand factor, protease inhibitor I08.954 MT1-MMP_Pericellular_Network CD44 antigen precursor Matrix metallopeptidase-2 Membrane-type matrix metallopeptidase-1 Syndecan-1 precursor Regulatory_Intramembrane_Proteolysis_Pathways Cyclic-AMP-dependent transcription factor ATF-6 alpha Cyclic-AMP-dependent transcription factor ATF-6 beta Endoplasmic reticulum chaperon grp78 (BiP) Endoribonuclease (EC 3.1.26.-) IRE1 Endoribonuclease (EC 3.1.26.-) IRE2 Eukaryotic translation initiation factor 2-alpha kinase 1 (HRI) Eukaryotic translation initiation factor 2-alpha kinase 2 (PKR) Eukaryotic translation initiation factor 2-alpha kinase 3 (PERK) Eukaryotic translation initiation factor 2-alpha kinase 4 (GCN2) Ins1, sterol regulated ER retention factor for SREBP-SCAP complexes Insig-1, sterol regulated ER retention factor for SREBP-SCAP complexes Insig-2, sterol regulated ER retention factor for SREBP-SCAP complexes Membrane-bound transcription factor site 2 protease S2P Membrane-bound transcription factor site-1 protease S1P Sterol regulatory element binding protein cleavage-activating protein Sterol regulatory element binding transcription factor Sterol regulatory element binding transcription factor 1 Sterol regulatory element binding transcription factor 2 Sterol regulatory element binding transcription factor sre1 Sterol regulatory element binding transcription factor sre2 cAMP responsive element binding protein 3 cAMP responsive element binding protein 3 (luman) cAMP responsive element binding protein 3-like 1 (oasis) cAMP responsive element binding protein 3-like 3 (CREB-H) cAMP responsive element binding protein 3-like 4 (CREB4) 02 Quorum sensing and biofilm formation Autoinducer_2_(AI-2)_transport_and_processing_(lsrACDBFGE_operon) Autoinducer 2 (AI-2) ABC transport system, fused AI2 transporter subunits and ATP-binding component Autoinducer 2 (AI-2) ABC transport system, membrane channel protein LsrC Autoinducer 2 (AI-2) ABC transport system, membrane channel protein LsrD Autoinducer 2 (AI-2) ABC transport system, periplasmic AI-2 binding protein LsrB Autoinducer 2 (AI-2) aldolase LsrF (EC 4.2.1.-) Autoinducer 2 (AI-2) kinase LsrK (EC 2.7.1.-) Autoinducer 2 (AI-2) modifying protein LsrG Autoinducer 2 sensor kinase/phosphatase LuxQ (EC 2.7.3.-) (EC 3.1.3.-) Autoinducer 2-binding periplasmic protein LuxP precursor LsrR, transcriptional repressor of lsr operon S-ribosylhomocysteine lyase (EC 4.4.1.21) Biofilm_Adhesin_Biosynthesis Biofilm PGA outer membrane secretin PgaA Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-) Biofilm PGA synthesis auxiliary protein PgaD Biofilm PGA synthesis deacetylase PgaB (EC 3.-) Biofilm_formation_in_Staphylococcus Accumulation-associated protein AAP Antiadhesin Pls, binding to squamous nasal epithelial cells Bifunctional autolysin Atl Biofilm operon icaABCD HTH-type negative transcriptional regulator IcaR Polysaccharide intercellular adhesin (PIA) biosynthesis N-glycosyltransferase IcaA (EC 2.4.-.-) Polysaccharide intercellular adhesin (PIA) biosynthesis deacetylase IcaB (EC 3.-.-.-) Polysaccharide intercellular adhesin (PIA) biosynthesis protein IcaC Polysaccharide intercellular adhesin (PIA) biosynthesis protein IcaD RNA polymerase sigma factor SigB Staphylococcal accessory regulator A (SarA) Teicoplanin-resistance associated HTH-type transcriptional regulator TcaR Transcriptional regulator of biofilm formation (AraC/XylS family) Quorum-sensing_in_Vibrio 8-amino-7-oxononanoate synthase (EC 2.3.1.47) / CqsA Autoinducer 1 sensor kinase/phosphatase LuxN (EC 2.7.3.-) (EC 3.1.3.-) Autoinducer 2 sensor kinase/phosphatase LuxQ (EC 2.7.3.-) (EC 3.1.3.-) Autoinducer 2-binding periplasmic protein LuxP precursor N-(3-hydroxybutanoyl)-L- homoserine lactone synthase LuxM Phosphorelay protein LuxU Quorum-sensing regulator of virulence HapR Regulatory protein LuxO S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS Sensor histidine kinase CqsS Quorum_sensing_in_Yersinia Homoserine lactone synthase YpeI N-3-oxododecanoyl-L-homoserine lactone quorum-sensing transcriptional activator N-3-oxohexanoyl-L-homoserine lactone quorum-sensing transcriptional activator N-3-oxohexanoyl-L-homoserine lactone synthase N-3-oxooctanoyl-L-homoserine lactone quorum-sensing transcriptional activator N-3-oxooctanoyl-L-homoserine lactone synthase N-acyl homoserine lactone hydrolase N-butyryl-L-homoserine lactone quorum-sensing transcriptional activator Quorum-sensing transcriptional activator YpeR Quorum-sensing transcriptional activator YspR Quorum_sensing_regulation_in_Pseudomonas BarA-associated response regulator UvrY (= GacA = SirA) Multiple virulence factor regulator MvfR/PqsR N-acyl-L-homoserine lactone synthetase LasI N-acyl-L-homoserine lactone synthetase RhlL PqsE, quinolone signal response protein QscR quorum-sensing control repressor Regulatory protein RsaL Transcriptional regulator LasR Transcriptional regulator RhlR Vfr transcriptional regulator Symbiotic_colonization_and_sigma-dependent_biofilm_formation_gene_cluster Acetyltransferase SypM Anti anti-sigma regulatory factor SypA Glycosyltransferase (EC 2.4.1.-) SypH Glycosyltransferase (EC 2.4.1.-) SypI Glycosyltransferase (EC 2.4.1.-) SypJ Glycosyltransferase SypN Glycosyltransferase SypP Glycosyltransferase SypQ Membrane protein SypL involved in exopolysaccharide production Oligosaccharide translocase SypK Outer membrane protein SypB Periplasmic protein SypC involved in polysaccharide export Polysaccharide biosynthesis chain length regulator SypO Predicted protein SypD Response regulator SypE Sigma-54 dependent transcriptional regulator SypG Signal transduction histidine kinase SypF Sugar transferase SypR involved in lipopolysaccharide synthesis 02 Regulation of virulence A_conserved_operon_linked_to_TyrR_and_possibly_involved_in_virulence Conserved protein YcjX with nucleoside triphosphate hydrolase domain Membrane protein YcjF SpeB-SpeF_extended_regulon Proteinase maturation protein (RopA) RopB Strepotococcal cysteine protease (Streptopain) (EC 3.4.22.10) Streptodornase B Streptopain inhibitor Streptococcal_Mga_Regulon Antiphagocytic M protein C5a peptidase (EC 3.4.21.-) Hypothetical mga-associated protein Immunogenic secreted protein M protein trans-acting positive regulator (Mga) Mga-associated protein Two-component system histidine kinase Two-component system response regulator Streptococcus_pyogenes_virulence_regulators FasL LuxS M protein trans-acting positive regulator (Mga) Multiple sugar metabolism regulator Negative transcriptional regulator Proteinase maturation protein (RopA) Response regulator CsrR RofA-like transcriptional regulator RopB Transcriptional regulator, RofA Transcriptional regulator, RofA-like Protein (RALP) Transmembrane histidine kinase CsrS Two-component_Response_Regulator_of_Virulence_ResDE DNA-binding response regulator ResD Sensor histidine kinase ResE (EC 2.7.3.-) VieSAB_signal_transduction_system_of_Vibrio Response regulator VieA Response regulator VieB Sensory box sensor histidine kinase/response regulator VieS 02 Signal transduction in Eukaryotes P38_MAP_kinase_pathways GTPase Rac1 MAP kinase ERK1 MAP kinase ERK2 MAP kinase ERK3 MAP kinase ERK4 MAP kinase ERK5 MAP kinase ERK8 MAP kinase JNK1 MAP kinase JNK2 MAP kinase JNK3 MAP kinase activated protein kinase MAPKAPK2 MAP kinase activated protein kinase MAPKAPK3 MAP kinase activated protein kinase MAPKAPK5 MAP kinase kinase MAP2K3 MAP kinase kinase MAP2K4 MAP kinase kinase MAP2K6 MAP kinase kinase kinase MAP3K1 MAP kinase kinase kinase MAP3K3 MAP kinase kinase kinase MAP3K9 MAP kinase p38 alpha MAP kinase p38 beta MAP kinase p38 delta MAP kinase p38 gamma Scaffoldin JIP-2 Scaffoldin OSM Serine, threonine protein kinase NLK 02 Cell_envelope-associated_LytR-CpsA-Psr_transcriptional_attenuators Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556) Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F1 (as in PMID19099556) Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F2 (as in PMID19099556) Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F4 (as in PMID19099556) Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily M (as in PMID19099556) Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily S (as in PMID19099556) Exopolysaccharide biosynthesis transcription antiterminator, LytR family Exopolysaccharide biosynthesis transcriptional activator EpsA Peptide methionine sulfoxide reductase regulator MsrR CytR_regulation Cyclic AMP receptor protein Transcriptional (co)regulator CytR DNA-binding_regulatory_proteins,_strays Alkanesulfonate utilization operon LysR-family regulator CbI Aromatic hydrocarbon utilization transcriptional regulator CatR (LysR family) Cyn operon transcriptional activator Cys regulon transcriptional activator CysB GltC, transcription activator of glutamate synthase operon Hydrogen peroxide-inducible genes activator LysR family transcriptional regulator PA0133 LysR family transcriptional regulator PA0191 LysR family transcriptional regulator PA0739 LysR family transcriptional regulator PA1145 LysR family transcriptional regulator PA2758 LysR family transcriptional regulator PA2877 LysR family transcriptional regulator PA3398 LysR family transcriptional regulator PA4989 LysR family transcriptional regulator PA5218 LysR family transcriptional regulator PA5437 LysR family transcriptional regulator STM2281 LysR family transcriptional regulator STM3121 LysR family transcriptional regulator YbhD LysR family transcriptional regulator YcjZ LysR family transcriptional regulator YdcI LysR family transcriptional regulator YfeR LysR family transcriptional regulator YfiE LysR family transcriptional regulator YhjC LysR family transcriptional regulator YneJ LysR family transcriptional regulator YnfL LysR family transcriptional regulator lrhA LysR family transcriptional regulator near succinyl-CoA:3-ketoacid-coenzyme A transferase Nitrogen assimilation regulatory protein Nac Transcriptional activator GpuR Transcriptional activator protein LysR Transcriptional regulator GbuR Xanthosine operon regulatory protein XapR, LysR family Global_Two-component_Regulator_PrrBA_in_Proteobacteria Dna binding response regulator PrrA (RegA) Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) HPr_catabolite_repression_system Catabolite control protein A Catabolite repression HPr-like protein Crh HPr kinase/phosphorylase (EC 2.7.1.-) (EC 2.7.4.-) Inorganic pyrophospatase PpaX Phosphocarrier protein of PTS system Orphan_regulatory_proteins Acetoacetate metabolism regulatory protein AtoC Copper sensory histidine kinase CpxA Copper sensory histidine kinase CusS Copper-sensing two-component system response regulator CpxR Copper-sensing two-component system response regulator CusR DNA transformation protein TfoX Glycine cleavage system transcriptional activator Glycine cleavage system transcriptional activator GcvA Glycine cleavage system transcriptional antiactivator GcvR Hybrid sensory histidine kinase in two-component regulatory system with EvgA Positive transcription regulator EvgA Putative sensor-like histidine kinase YfhK Putative sensory histidine kinase YfhA Putative two component system histidine kinase YedV Putative two-component response regulator and GGDEF family protein YeaJ Putative two-component system response regulator YedW Sensor kinase CitA, DpiB (EC 2.7.3.-) Sensor protein basS/pmrB (EC 2.7.3.-) Sensory histidine kinase AtoS Sensory histidine kinase CreB Sensory histidine kinase QseC Sensory histidine kinase in two-component regulatory system with RstA Transcriptional regulatory protein CitB, DpiA Transcriptional regulatory protein RstA Transcriptional regulatory protein basR/pmrA Two-component nitrogen fixation transcriptional regulator FixJ Two-component oxygen-sensor histidine kinase FixL Two-component sensor histidine kinase PleC Two-component system response regulator CreC Two-component system response regulator QseB Oxygen_and_light_sensor_PpaA-PpsR Heme oxygenase (EC 1.14.99.3) Heme-binding SCHIC domain protein, putative oxygen sensor Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-) PpaA, heme-binding SCHIC domain sensory protein, regulator for photosystem formation Transcriptional regulator, PpsR Pseudomonas_quinolone_signal_PQS Anthranilate synthase, amidotransferase component (EC 4.1.3.27) [PQS biosynthesis] Anthranilate synthase, aminase component (EC 4.1.3.27) [PQS biosynthesis] BarA-associated response regulator UvrY (= GacA = SirA) Hypothetical protein in AHQ biosynthetic operon Multiple virulence factor regulator MvfR/PqsR N-acyl-L-homoserine lactone synthetase LasI PQS biosynthesis protein PqsA, anthranilate-CoA ligase (EC 6.2.1.32) PQS biosynthesis protein PqsB, similar to 3-oxoacyl-[acyl-carrier-protein] synthase III PQS biosynthesis protein PqsC, similar to 3-oxoacyl-[acyl-carrier-protein] synthase III PQS biosynthesis protein PqsD, similar to 3-oxoacyl-[acyl-carrier-protein] synthase III PQS biosynthesis protein PqsH, similar to FAD-dependent monooxygenases PqsE, quinolone signal response protein Putative 3-oxoacyl-[acyl-carrier-protein] synthase III in AHQ biosynthetic operon, related to PqsB Putative non-ribosomal peptide synthetase in AHQ biosynthetic operon Transcriptional regulator LasR Rcs_phosphorelay_signal_transduction_pathway Colanic acid capsular biosynthesis activation accesory protein RcsA, co-regulator with RcsB DNA-binding capsular synthesis response regulator RcsB DnaJ-like protein DjlA Protein RcsF Two-component sensor protein RcsC (EC 2.7.3.-) Two-component sensor protein RcsD (EC 2.7.3.-) Sex_pheromones_in_Enterococcus_faecalis_and_other_Firmicutes Aggregation substance Asa1/PrgB Heptaprenyl diphosphate synthase component I (EC 2.5.1.30) Heptaprenyl diphosphate synthase component II (EC 2.5.1.30) Hypothetical similar to thiamin biosynthesis lipoprotein ApbE Lipoprotein signal peptidase (EC 3.4.23.36) Membrane-associated zinc metalloprotease NADH dehydrogenase (EC 1.6.99.3) in cluster with putative pheromone precursor Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) Pheromone cAD1 precursor lipoprotein Cad Pheromone response surface protein PrgC Putative pheromone cAM373 precursor lipoprotein CamS Putative pheromone precursor lipoprotein Putative prenyltransferase, contains 1,4-dihydroxy-2-naphthoate octaprenyltransferase domain Surface exclusion protein Sea1/PrgA Stringent_Response,_(p)ppGpp_metabolism D-tyrosyl-tRNA(Tyr) deacylase GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC 3.6.1.40) The_Chv_regulatory_system_of_Alphaproteobacteria ATP-binding protein ManX DNA-binding response regulator ChvI HPr kinase/phosphorylase (EC 2.7.1.-) (EC 2.7.4.-) PTS system permease (IIAMan), nitrogen regulatory IIA protein Phosphocarrier protein, nitrogen regulation associated Sensor histidine kinase ChvG (EC 2.7.3.-) Trans-envelope_signaling_system_VreARI_in_Pseudomonas Extracytoplasmic function (ECF) sigma factor VreI Filamentous haemagglutinin family outer membrane protein associated with VreARI signalling system Hemolysin activation/secretion protein associated with VreARI signalling system Outer membrane TonB-dependent transducer VreA of trans-envelope signaling system Putative PpiC-type peptidyl-prolyl cis-trans isomerase precursor associated with VreARI signaling system Putative outer membrane TonB-dependent receptor associated with haemagglutinin family outer membrane protein Sigma factor regulator VreR (cytoplasmic membrane-localized) of trans-envelope signaling system Two-component_regulatory_systems_in_Campylobacter Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY Flagellar sensory histidine kinase FlgS Positive regulator of CheA protein activity (CheW) Putative two-component response regulator Putative two-component sensor histidine kinase Signal transduction histidine kinase CheA (EC 2.7.3.-) Signal-transduction regulatory protein FlgR Two-component system histidine kinase Two-component system histidine kinase DccS Two-component system histidine kinase RacS Two-component system response regulator Two-component system response regulator DccR Two-component system response regulator RacR WhiB_and_WhiB-type_regulatory_proteins_ Sporulation regulatory protein WhiB Sporulation regulatory protein WhiD WhiB-family transcriptional regulator WhiB-like transcription regulator WhiB-like transcriptional regulator WhiB-type transcription regulator WhiB-type transcriptional regulator Zinc_regulated_enzymes C4-type zinc finger protein, DksA/TraR family Carbonic anhydrase (EC 4.2.1.1) Carbonic anhydrase, gamma class (EC 4.2.1.1) Cysteinyl-tRNA synthetase (EC 6.1.1.16) Dihydroorotase (EC 3.5.2.3) GTP cyclohydrolase I (EC 3.5.4.16) type 1 GTP cyclohydrolase I (EC 3.5.4.16) type 2 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) Porphobilinogen synthase (EC 4.2.1.24) Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family Queuosine biosynthesis QueD, PTPS-I Zinc uptake regulation protein ZUR cAMP_signaling_in_bacteria 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) Adenine phosphoribosyltransferase (EC 2.4.2.7) Adenylate cyclase (EC 4.6.1.1) Adenylate/guanylate cyclase (EC 4.6.1.2) CAMP phosphodiesterases class-II:Metallo-beta-lactamase superfamily Cyclic AMP receptor protein ElaA protein Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-) Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase Predicted signal-transduction protein containing cAMP-binding and CBS domains Prophage Clp protease-like protein Purine cyclase-related protein Putative Heme-regulated two-component response regulator Putative hemin-binding lipoprotein Putative insecticidal toxin complex adenylate cyclase ExoY anthrax toxin moiety, protective antigen, pagA formerly pag, plasmid pXO1, B. anthracis (M22589, P13423) bifunctional hemolysin-adenylate cyclase precursor cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases cAMP-dependent Kef-type K+ transport system calmodulin sensitive adenylate cyclase, edema factor, cya, plasmid pXO1, B. anthracis (M23179, M24074) cyclolysin secretion ATP-binding protein cyclolysin secretion protein cyclolysin-activating lysine-acyltransferase trans-acting positive regulator (Atx A) transcriptional activator AtxA, (pXO1-119) 01 Respiration 02 ATP synthases F0F1-type_ATP_synthase ATP synthase A chain (EC 3.6.3.14) ATP synthase B chain (EC 3.6.3.14) ATP synthase B' chain (EC 3.6.3.14) ATP synthase C chain (EC 3.6.3.14) ATP synthase alpha chain (EC 3.6.3.14) ATP synthase beta chain (EC 3.6.3.14) ATP synthase delta chain (EC 3.6.3.14) ATP synthase epsilon chain (EC 3.6.3.14) ATP synthase gamma chain (EC 3.6.3.14) ATP synthase protein I V-Type_ATP_synthase Archaeal-type H+-ATPase subunit H V-type ATP synthase subunit A (EC 3.6.3.14) V-type ATP synthase subunit B (EC 3.6.3.14) V-type ATP synthase subunit C (EC 3.6.3.14) V-type ATP synthase subunit D (EC 3.6.3.14) V-type ATP synthase subunit E (EC 3.6.3.14) V-type ATP synthase subunit F (EC 3.6.3.14) V-type ATP synthase subunit G (EC 3.6.3.14) V-type ATP synthase subunit H (EC 3.6.3.14) V-type ATP synthase subunit I (EC 3.6.3.14) V-type ATP synthase subunit K (EC 3.6.3.14) 02 Electron accepting reactions Anaerobic_respiratory_reductases Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) Anaerobic dehydrogenases, typically selenocysteine-containing Anaerobic dimethyl sulfoxide reductase chain A (EC 1.8.99.-) Anaerobic dimethyl sulfoxide reductase chain B (EC 1.8.99.-) Anaerobic dimethyl sulfoxide reductase chain C (EC 1.8.99.-) Anaerobic sulfite reductase subunit A Anaerobic sulfite reductase subunit B Anaerobic sulfite reductase subunit C (EC 1.8.1.-) Arsenate reductase (EC 1.20.4.1) Butyryl-CoA dehydrogenase (EC 1.3.99.2) CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D (EC 1.8.98.1) CoB--CoM heterodisulfide reductase 2 subunit E (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit A (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit B (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit C (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit D (EC 1.8.98.1) CoB--CoM-reducing hydrogenase (Cys) delta subunit Coenzyme F420-dependent oxidoreductase Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1) F420-dependent sulfite reductase Fe-S-cluster-containing hydrogenase components 1 Ferredoxin reductase Ferric reductase (1.6.99.14) Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Formate dehydrogenase -O, gamma subunit (EC 1.2.1.2) Heterodisulfide reductase, cytochrome reductase subunit Heterodisulfide reductase, subunit A Polysulfide reductase, subunit A, putative Polysulfide reductase, subunit B, putative Polysulfide reductase, subunit C, putative Sulfite reductase alpha subunit (EC 1.8.99.1) Sulfite reductase beta subunit (EC 1.8.99.1) Sulfite reductase, dissimilatory-type gamma subunit (EC 1.8.99.3) Thiosulfate reductase cytochrome B subunit Thiosulfate reductase electron transport protein phsB Thiosulfate reductase precursor (EC 1.-.-.-) Uncharacterized component of anaerobic dehydrogenases Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) heterodisulfide reductase, iron-sulfur binding subunit, putative heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta heterodisulfide reductase, subunit E, putative polysulfide reductase, subunit A polysulfide reductase, subunit B polysulfide reductase, subunit C Terminal_AA3-600_quinol_oxidase AA3-600 quinol oxidase subunit I AA3-600 quinol oxidase subunit II AA3-600 quinol oxidase subunit IIII AA3-600 quinol oxidase subunit IV Terminal_cytochrome_C_oxidases Alternative cytochrome c oxidase polypeptide CoxM (EC 1.9.3.1) Alternative cytochrome c oxidase polypeptide CoxN (EC 1.9.3.1) Alternative cytochrome c oxidase polypeptide CoxO (EC 1.9.3.1) Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1) Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1) Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1) Cytochrome c oxidase polypeptide I (EC 1.9.3.1) Cytochrome c oxidase polypeptide II (EC 1.9.3.1) Cytochrome c oxidase polypeptide IIA (EC 1.9.3.1) Cytochrome c oxidase polypeptide III (EC 1.9.3.1) Cytochrome c oxidase polypeptide IV(EC 1.9.3.1) Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) Cytochrome c oxidase, subunit IV (EC 1.9.3.1) Cytochrome c553-like FixO3 cytochrome-c oxidase subunit Heme bearing subunit I of the terminal oxidase (DoxB) Quinol oxidase (SoxABC), cytochrome aa3 subunit (SoxB) Quinol oxidase-2, subunit II (SoxH) Terminal oxidase, small hydrophobic subunit (DoxE) Terminal oxidase, subunit (DoxC) Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation Type cbb3 cytochrome oxidase biogenesis protein CcoS, involved in heme b insertion cb-type cytochrome c oxidase subunit IV [EC:1.9.3.1] hypothetical cytochrome c oxidase polypeptide I membrane c-type cytochrome cy probable cytochrome oxidase (cbb3-type) quinol oxidase polypeptide I QoxB (EC:1.9.3.-) quinol oxidase polypeptide II QoxA (EC:1.9.3.-) quinol oxidase polypeptide III QoxC (EC:1.9.3.-) quinol oxidase polypeptide IV QoxD (EC:1.9.3.-) Terminal_cytochrome_O_ubiquinol_oxidase Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) Terminal_cytochrome_d_ubiquinol_oxidases Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) Hypothetical bd-type Menaquinol oxidase subunit Transport ATP-binding protein CydC Transport ATP-binding protein CydCD Transport ATP-binding protein CydD cytochrome oxidase,subunit I (cydA-1) putative Cytochrome bd2, subunit I putative Cytochrome bd2, subunit II Terminal_cytochrome_oxidases AA3-600 quinol oxidase subunit I AA3-600 quinol oxidase subunit II AA3-600 quinol oxidase subunit IIII AA3-600 quinol oxidase subunit IV Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) Transport ATP-binding protein CydC Transport ATP-binding protein CydCD Transport ATP-binding protein CydD putative Cytochrome bd2, subunit I putative Cytochrome bd2, subunit II Tetrathionate_respiration Octaheme tetrathionate reductase Tetrathionate reductase sensory transduction histidine kinase Tetrathionate reductase subunit A Tetrathionate reductase subunit B Tetrathionate reductase subunit C Tetrathionate reductase two-component response regulator Ubiquinone_Menaquinone-cytochrome_c_reductase_complexes 14 kDa peptide of ubiquinol-cytochrome C2 oxidoreductase complex Menaquinone-cytochrome C oxidoreductase, cytochrome C subunit Menaquinone-cytochrome C reductase iron-sulfur subunit Menaquinone-cytochrome c reductase, cytochrome B subunit Quinol oxidase-2, sulfocyanin (blue copper protein) (SoxE) TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) Ubiquinol-cytochrome C reductase complex core protein I, mitochondrial precursor (EC 1.10.2.2) Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit trimethylamine_N-oxide_(TMAO)_reductase Biotin sulfoxide reductase (EC 1.-.-.-) Cytochrome c-type protein NapC Cytochrome c-type protein TorC Cytochrome c-type protein TorY Functional role page for Chaperone protein TorD Functional role page for TorCAD operon transcriptional regulatory protein TorR Hypothetical iron-sulfur cluster binding protein YccM Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Periplasmic protein torT precursor Sensor protein torS (EC 2.7.3.-) Trimethylamine-N-oxide reductase (Cytochrome c) (EC 1.7.2.3) Trimethylamine-N-oxide reductase (EC 1.6.6.9) WARNINIG TorE protein 02 Electron donating reactions CO_Dehydrogenase CO dehydrogenases maturation factor, CoxF family Carbon monoxide dehydrogenase F protein Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 ) Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) parolog without usual motifs Carbon monoxide dehydrogenase large chain (EC 1.2.99.2) without typical motifs Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2) Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) Carbon-monoxide dehydrogenase form II, large subunit (EC 1.2.99.2) Hypothetical lactonase in carbon monoxide dehydrogenase cluster Transcription regulator in CO-DH cluster Uncharacterized MobA-related protein carbon monoxide dehydrogenase D protein carbon monoxide dehydrogenase E protein carbon monoxide dehydrogenase G protein carbon monoxide dehydrogenase operon C protein Coenzyme_F420-H2_dehydrogenase_(methanophenazine) Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoA Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoB Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoC Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoD Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoF Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoH Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoI Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoJ Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoJ2 Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoK Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoL Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoM Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoN Coenzyme F(420)H(2) dehydrogenase (methanophenazine) subunit FpoO Coenzyme_F420_hydrogenase Coenzyme F420 hydrogenase alpha subunit (FrcA) (EC 1.12.98.1) Coenzyme F420 hydrogenase alpha subunit (FruA) (EC 1.12.98.1) Coenzyme F420 hydrogenase beta subunit (FrcB) (EC 1.12.98.1) Coenzyme F420 hydrogenase beta subunit (FruB) (EC 1.12.98.1) Coenzyme F420 hydrogenase gamma subunit (FrcG) (EC 1.12.98.1) Coenzyme F420 hydrogenase gamma subunit (FruG) (EC 1.12.98.1) Coenzyme F420 hydrogenase maturation protease (EC 3.4.24.-) Putative coenzyme F420-dependent oxidoreductase MJ1349 coenzyme F420-reducing hydrogenase, beta subunit homolog Energy-conserving_hydrogenase_(ferredoxin) Energy-conserving hydrogenase (ferredoxin), subunit A Energy-conserving hydrogenase (ferredoxin), subunit B Energy-conserving hydrogenase (ferredoxin), subunit C Energy-conserving hydrogenase (ferredoxin), subunit D Energy-conserving hydrogenase (ferredoxin), subunit E Energy-conserving hydrogenase (ferredoxin), subunit F Formate_dehydrogenase Formate dehydrogenase H (EC 1.2.1.2) Formate dehydrogenase N alpha subunit (EC 1.2.1.2) Formate dehydrogenase N beta subunit (EC 1.2.1.2) Formate dehydrogenase N gamma subunit (EC 1.2.1.2) Formate dehydrogenase O alpha subunit (EC 1.2.1.2) Formate dehydrogenase O beta subunit (EC 1.2.1.2) Formate dehydrogenase O gamma subunit (EC 1.2.1.2) Formate dehydrogenase alpha subunit (EC 1.2.1.2) Formate dehydrogenase beta subunit (EC 1.2.1.2) H2:CoM-S-S-HTP_oxidoreductase CoB--CoM heterodisulfide reductase subunit A (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit B (EC 1.8.98.1) CoB--CoM heterodisulfide reductase subunit C (EC 1.8.98.1) CoB--CoM-reducing hydrogenase (Cys) alpha subunit CoB--CoM-reducing hydrogenase (Cys) beta subunit CoB--CoM-reducing hydrogenase (Cys) delta subunit CoB--CoM-reducing hydrogenase (Cys) gamma subunit CoB--CoM-reducing hydrogenase (Sec) alpha subunit CoB--CoM-reducing hydrogenase (Sec) alpha' subunit CoB--CoM-reducing hydrogenase (Sec) beta subunit CoB--CoM-reducing hydrogenase (Sec) delta subunit CoB--CoM-reducing hydrogenase (Sec) gamma subunit Hydrogenases Coenzyme F420 hydrogenase beta subunit (FruB) (EC 1.12.98.1) Coenzyme F420 hydrogenase maturation protease (EC 3.4.24.-) Coenzyme F420-reducing hydrogenase, alpha subunit Coenzyme F420-reducing hydrogenase, beta subunit Coenzyme F420-reducing hydrogenase, gamma subunit Fe-S-cluster-containing hydrogenase components 1 Fe-S-cluster-containing hydrogenase components 2 Methanophenazine hydrogenase cytochrome b subunit (EC 1.12.98.3) Methanophenazine hydrogenase large subunit (EC 1.12.98.3) Methanophenazine hydrogenase small subunit precursor (EC 1.12.98.3) NAD-reducing hydrogenase subunit HoxE (EC 1.12.1.2) NAD-reducing hydrogenase subunit HoxF (EC 1.12.1.2) NAD-reducing hydrogenase subunit HoxH (EC 1.12.1.2) NAD-reducing hydrogenase subunit HoxU (EC 1.12.1.2) NAD-reducing hydrogenase subunit HoxY (EC 1.12.1.2) NADH-reducing hydrogenase maturation factor NADP-reducing hydrogenase, subunit A NADP-reducing hydrogenase, subunit B NADP-reducing hydrogenase, subunit C Ni,Fe-hydrogenase I cytochrome b subunit Ni,Fe-hydrogenase I large subunit Ni,Fe-hydrogenase III large subunit Ni,Fe-hydrogenase III small subunit Ni,Fe-hydrogenase maturation factor Ni/Fe-hydrogenase 2 B-type cytochrome subunit Nickel-dependent hydrogenase, large subunit Nickel-dependent hydrogenase, small subunit Periplasmic [Fe] hydrogenase (EC 1.12.7.2) Periplasmic [Fe] hydrogenase large subunit (EC 1.12.7.2) Periplasmic [Fe] hydrogenase small subunit (EC 1.12.7.2) Probable Ni/Fe-hydrogenase 2 B-type cytochrome subunit Protein hydE Quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit Quinone-reactive Ni/Fe-hydrogenase large chain (EC 1.12.5.1) Quinone-reactive Ni/Fe-hydrogenase small chain precursor (EC 1.12.5.1) Signal transduction histidine kinase HoxJ (hydrogenase regulation) Signal transduction histidine kinase for Quinone-reactive Ni/Fe-hydrogenase Sulfhydrogenase II subunit a Sulfhydrogenase II subunit b Sulfhydrogenase II subunit d Sulfhydrogenase II subunit g Uptake hydrogenase large subunit (EC 1.12.99.6) Uptake hydrogenase small subunit precursor (EC 1.12.99.6) [Fe] hydrogenase gamma (EC 1.12.7.2) [Fe] hydrogenase, HymA subunit, putative [Fe] hydrogenase, HymB subunit, putative [Fe] hydrogenase, HymD subunit, putative [Ni/Fe] hydrogenase, group 1, large subunit [Ni/Fe] hydrogenase, group 1, small subunit cytochrome-c3 hydrogenase alpha chain cytochrome-c3 hydrogenase delta chain cytochrome-c3 hydrogenase gamma chain heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta hydrogenase (cytochrome-c3 hydrogenase beta chain) hydrogenase, (NiFe)/(NiFeSe) small subunit family hydrogenase, methyl-violgen-reducing type, delta subunit hydrogenase, subunit gamma related protein hydrogenase/sulfur reductase, alpha subunit hydrogenase/sulfur reductase, beta subunit hydrogenase/sulfur reductase, delta subunit hydrogenase/sulfur reductase, gamma subunit methyl viologen-reducing hydrogenase, delta subunit homolog FlpD quinone-reactive Ni/Fe-hydrogenase, small subunit Methanophenazine_hydrogenase Methanophenazine hydrogenase cytochrome b subunit (EC 1.12.98.3) Methanophenazine hydrogenase large subunit (EC 1.12.98.3) Methanophenazine hydrogenase maturation protease (EC 3.4.24.-) Methanophenazine hydrogenase small subunit precursor (EC 1.12.98.3) Na(+)-translocating_NADH-quinone_oxidoreductase_and_rnf-like_group_of_electron_transport_complexes Electron transport complex protein RnfA Electron transport complex protein RnfB Electron transport complex protein RnfC Electron transport complex protein RnfD Electron transport complex protein RnfE Electron transport complex protein RnfG Hypothetical protein in ApbE locus Na(+)-translocating NADH-quinone reductase subunit A (EC 1.6.5.-) Na(+)-translocating NADH-quinone reductase subunit B (EC 1.6.5.-) Na(+)-translocating NADH-quinone reductase subunit C (EC 1.6.5.-) Na(+)-translocating NADH-quinone reductase subunit D (EC 1.6.5.-) Na(+)-translocating NADH-quinone reductase subunit E (EC 1.6.5.-) Na(+)-translocating NADH-quinone reductase subunit F (EC 1.6.5.-) Probable exported or periplasmic protein in ApbE locus probable exported protein YPO3233 NiFe_hydrogenase_maturation Coenzyme F420 hydrogenase alpha subunit (FrcA) (EC 1.12.98.1) Coenzyme F420 hydrogenase alpha subunit (FruA) (EC 1.12.98.1) Energy-conserving hydrogenase (ferredoxin), subunit A Methanophenazine hydrogenase large subunit (EC 1.12.98.3) [NiFe] hydrogenase metallocenter assembly protein HybG [NiFe] hydrogenase metallocenter assembly protein HypC [NiFe] hydrogenase metallocenter assembly protein HypD [NiFe] hydrogenase metallocenter assembly protein HypE [NiFe] hydrogenase metallocenter assembly protein HypF [NiFe] hydrogenase nickel incorporation HybF-like protein [NiFe] hydrogenase nickel incorporation protein HybF [NiFe] hydrogenase nickel incorporation protein HypA [NiFe] hydrogenase nickel incorporation-associated protein HypB Respiratory_Complex_I F420H2:quinone oxidoreductase, 11.2 kDa subunit, putative F420H2:quinone oxidoreductase, 39 kDa subunit, putative Hypothetical transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5 homolog NAD(P)H-quinone oxidoreductase chain 1 NAD(P)H-quinone oxidoreductase chain 5 (EC 1.6.5.2) NAD(P)H-quinone oxidoreductase chain H (EC 1.6.5.2) NAD(P)H-quinone oxidoreductase chain I (EC 1.6.5.2) NAD(P)H-quinone oxidoreductase chain J (EC 1.6.5.2) NAD(P)H-quinone oxidoreductase chain K (EC 1.6.5.2) NAD(P)H-quinone oxidoreductase subunit 3 (EC 1.6.5.2) NADH dehydrogenase I subunit 4, Involved in photosystem-1 cyclic electron flow NADH dehydrogenase I subunit 5, Involved in photosystem-1 cyclic electron flow NADH dehydrogenase subunit 1 NADH dehydrogenase subunit 2 NADH dehydrogenase subunit 3 NADH dehydrogenase subunit 4L NADH dehydrogenase subunit 5 NADH dehydrogenase, subunit 5 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) NADH-quinone oxidoreductase chain F 2 (EC 1.6.99.5) NADH-quinone oxidoreductase subunit 15 (EC 1.6.99.5) NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) homolog NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain G2 (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) NADH:ubiquinone oxidoreductase 17.2 kD subunit Putative subunit of NAD(P)H:quinone oxidoreductase Respiratory_dehydrogenases_1 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) Anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) Anaerobic glycerol-3-phosphate dehydrogenase subunit B (EC 1.1.5.3) Anaerobic glycerol-3-phosphate dehydrogenase subunit C (EC 1.1.5.3) D-Lactate dehydrogenase (EC 1.1.2.5) D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster D-amino acid dehydrogenase large subunit (EC 1.4.99.1) D-amino acid dehydrogenase small subunit (EC 1.4.99.1) Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site Glycerol dehydrogenase (EC 1.1.1.6) Glycerol-1-phosphate dehydrogenase [NAD(P)] (EC 1.1.1.261) Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) L-lactate dehydrogenase (EC 1.1.2.3) Methanol dehydrogenase large subunit protein (EC 1.1.99.8) Methylamine dehydrogenase heavy chain precursor (EC 1.4.99.3) Methylamine dehydrogenase light chain precursor (EC 1.4.99.3) NADH dehydrogenase (EC 1.6.99.3) Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) Sn-glycerol-3-phosphate dehydrogenase (Aerobic) (Aerobic glycerol-3-phosphate dehydrogenase)(EC 1.1.99.5) putative Fe-S, FMN containing oxidoreductase quinoprotein alcohol dehydrogenase Succinate_dehydrogenase Fumarate reductase cytochrome b subunit Fumarate reductase flavoprotein subunit (EC 1.3.99.1) Fumarate reductase subunit C Fumarate reductase subunit D Hypothetical succinate dehydrogenase membrane anhor protein Putative succinate dehydrogenase cytochrome b subunit Succinate dehydrogenase cytochrome b subunit Succinate dehydrogenase cytochrome b-556 subunit Succinate dehydrogenase cytochrome b558 subunit Succinate dehydrogenase cytochrome b560 subunit Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Succinate dehydrogenase hydrophobic membrane anchor protein Succinate dehydrogenase hydrophobic membrane anchor protein(Nostoc p.) Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal:FAD dependent oxidoreductase putative succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase) 02 Sodium Ion-Coupled Energetics Na+_translocating_decarboxylases_and_related_biotin-dependent_enzymes Biotin carboxyl carrier protein of glutaconyl-CoA decarboxylase Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase Biotin carboxyl carrier protein of methylmalonyl-CoA:Pyruvate transcarboxylase Biotin carboxyl carrier protein of oxaloacetate decarboxylase Glutaconyl-CoA decarboxylase alpha chain (EC 4.1.1.70) Glutaconyl-CoA decarboxylase beta chain (EC 4.1.1.70) Glutaconyl-CoA decarboxylase delta chain (EC 4.1.1.70) Membrane protein associated with methylmalonyl-CoA decarboxylase Membrane protein associated with oxaloacetate decarboxylase Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) Methylmalonyl-CoA:Pyruvate transcarboxylase 12S subunit (EC 2.1.3.1) Methylmalonyl-CoA:Pyruvate transcarboxylase 5S subunit (EC 2.1.3.1) Oxaloacetate decarboxylase alpha chain (EC 4.1.1.3) Oxaloacetate decarboxylase beta chain (EC 4.1.1.3) Oxaloacetate decarboxylase gamma chain (EC 4.1.1.3) 02 Biogenesis_of_c-type_cytochromes ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA ABC transporter involved in cytochrome c biogenesis, CcmB subunit Ccs1/ResB-related putative cytochrome C-type biogenesis protein Cytochrome c heme lyase subunit CcmF Cytochrome c heme lyase subunit CcmH Cytochrome c heme lyase subunit CcmL Cytochrome c-type biogenesis protein CcdA (DsbD analog) Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE Cytochrome c-type biogenesis protein CcmD, interacts with CcmCE Cytochrome c-type biogenesis protein CcmE, heme chaperone Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase Cytochrome c-type biogenesis protein Ccs1/ResB Cytochrome c-type biogenesis protein CcsA/ResC Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) Cytochrome c-type biogenesis protein ResA Cytochrome c-type biogenesis protein, archaeal, distantly related to heme lyase subunit CcmF Hypothetical distantly related to thiol:disulfide interchange protein DsbA Hypothetical protein associated with short form of CcmH Hypothetical protein distantly related to cytochrome C-type biogenesis protein CcdA Hypothetical protein distantly related to putative heme lyase CcmC Periplasmic thiol:disulfide interchange protein DsbA Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation Predicted transporter accosiated with cytochrome c biogenesis Putative ATP-binding component of ABC transporter involved in cytochrome c biogenesis Putative cytochrome C-type biogenesis protein Putative cytochrome c biogenesis factor, archaeal Putative cytochrome c-type biogenesis protein related to CcmF Putative thiol:disulfide oxidoreductase involved in cytochrome C-type biogenesis Similar to cytochrome c-type biogenesis protein CcsA/ResC Thiol:disulfide oxidoreductase TlpA Thiol:disulfide oxidoreductase related to ResA Biogenesis_of_cbb3-type_cytochrome_c_oxidases Putative analog of CcoH, COG3198 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation Type cbb3 cytochrome oxidase biogenesis protein CcoH Type cbb3 cytochrome oxidase biogenesis protein CcoI Type cbb3 cytochrome oxidase biogenesis protein CcoS, involved in heme b insertion Biogenesis_of_cytochrome_c_oxidases Copper metallochaperone, bacterial analog of Cox17 protein Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion Ferredoxin--NADP(+) reductase (EC 1.18.1.2) Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB Hypotehtical protein in Cytochrome oxidase biogenesis cluster Sco1/SenC/PrrC protein family Carbon_monoxide_dehydrogenase_maturation_factors Carbon monoxide dehydrogenase F protein Putative Carbon monoxide dehydrogenase subunit, maturation factor carbon monoxide dehydrogenase D protein carbon monoxide dehydrogenase E protein carbon monoxide dehydrogenase G protein Carbon_monoxide_induced_hydrogenase 5-methyltetrahydrofolate:corrinoid iron-sulfur protein methyltransferase 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase Acetyl-CoA synthase corrinoid iron-sulfur protein, large subunit Acetyl-CoA synthase corrinoid iron-sulfur protein, small subunit CO dehydrogenase accessory protein CooC (nickel insertion) CO dehydrogenase iron-sulfur protein CooF (EC 1.2.99.2) CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex (EC 1.2.99.2) CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase (EC 2.3.1.169) CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit CO dehydrogenase/acetyl-CoA synthase subunit epsilon, CO dehydrogenase subcomplex (EC 1.2.99.2) CO dehydrogenase/acetyl-CoA synthase subunit gamma, corrinoid iron-sulfur subcomplex large subunit CO dehydrogenase/acetyl-CoA synthase, CO dehydrogenase subunit (EC 1.2.99.2) CO dehydrogenase/acetyl-CoA synthase, acetyl-CoA synthase subunit (EC 2.3.1.169) Carbon monoxide dehydrogenase CooS subunit (EC 1.2.99.2) Carbon monoxide-induced hydrogenase NuoC-like protein CooU Carbon monoxide-induced hydrogenase iron-sulfur protein CooX Carbon monoxide-induced hydrogenase large subunit CooH Carbon monoxide-induced hydrogenase membrane protein CooM Carbon monoxide-induced hydrogenase proton translocating subunit CooK Carbon monoxide-induced hydrogenase small subunit CooL Carbon monoxide-responsive transcriptional activator CooA CooJ CooT Iron-sulfur protein clustered with CO dehydrogenase/acetyl-CoA synthase Similar to carbon monoxide dehydrogenase CooS subunit Cytochrome_B6-F_complex Cytochrome b6-f complex alternative Rieske iron sulfur protein PetC2 Cytochrome b6-f complex alternative Rieske iron sulfur protein PetC3 Cytochrome b6-f complex iron-sulfur subunit PetC1 (Rieske iron sulfur protein EC 1.10.99.1) Cytochrome b6-f complex subunit IV (PetD) Cytochrome b6-f complex subunit V (PetG) Cytochrome b6-f complex subunit VI (PetL) Cytochrome b6-f complex subunit VII (PetM) Cytochrome b6-f complex subunit VIII (PetN) Cytochrome b6-f complex subunit, apocytochrome f Cytochrome b6-f complex subunit, cytochrome b6 Cytochrome b6-f complex subunit, cytochrome b6, putative Ferredoxin-NADP(+) reductase (EC 1.18.1.2) Flavocytochrome_C Flavocytochrome c flavin subunit Flavocytochrome c heme subunit Formate_hydrogenase Formate dehydrogenase -O, gamma subunit (EC 1.2.1.2) Formate dehydrogenase N alpha subunit (EC 1.2.1.2) Formate dehydrogenase N beta subunit (EC 1.2.1.2) Formate dehydrogenase N gamma subunit (EC 1.2.1.2) Formate dehydrogenase O alpha subunit (EC 1.2.1.2) Formate dehydrogenase O beta subunit (EC 1.2.1.2) Formate dehydrogenase O gamma subunit (EC 1.2.1.2) Formate dehydrogenase O putative subunit Formate dehydrogenase chain D (EC 1.2.1.2) Formate dehydrogenase putative subunit (EC 1.2.1.2) Formate dehydrogenase related protein Formate dehydrogenase-O, iron-sulfur subunit (EC 1.2.1.2) Formate dehydrogenase-O, major subunit (EC 1.2.1.2) Formate hydrogenlyase hypothetical subunit Formate hydrogenlyase regulatory protein HycA Formate hydrogenlyase subunit 2 Formate hydrogenlyase subunit 3 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Formate hydrogenlyase subunit 4 Formate hydrogenlyase subunit 5 Formate hydrogenlyase subunit 6 Formate hydrogenlyase subunit 7 Formate hydrogenlyase transcriptional activator Hydrogenase-4 component A (EC 1.-.-.-) Hydrogenase-4 component B (EC 1.-.-.-) Hydrogenase-4 component C (EC 1.-.-.-) Hydrogenase-4 component D (EC 1.-.-.-) Hydrogenase-4 component E (EC 1.-.-.-) Hydrogenase-4 component F (EC 1.-.-.-) Hydrogenase-4 component G (EC 1.-.-.-) Hydrogenase-4 component H (EC 1.-.-.-) Hydrogenase-4 component I (EC 1.-.-.-) Hydrogenase-4 transcriptional activator Hypothetical protein YrhD Hypothetical protein probably related to Formate dehydrogenase function NAD-dependent formate dehydrogenase (EC 1.2.1.2) NAD-dependent formate dehydrogenase alpha subunit NAD-dependent formate dehydrogenase beta subunit NAD-dependent formate dehydrogenase delta subunit NAD-dependent formate dehydrogenase gamma subunit Putative formate dehydrogenase iron-sulfur subunit (EC 1.2.1.2) Putative formate dehydrogenase oxidoreductase protein Putative formate dehydrogenase, cytochrome B subunit (EC 1.2.1.2) Putative formate dehydrogenase-specific chaperone formate dehydrogenase formation protein FdhE hydrogenase, HycC subunit, putative hydrogenase, group 4, HycE subunit, putative hydrogenase, group 4, HycG subunit, putative tungsten-containing formate dehydrogenase alpha subunit tungsten-containing formate dehydrogenase beta subunit Quinone_oxidoreductase_family NADPH:quinone reductase (Quinone oxidoreductase) (EC 1.6.5.5) Putative NADP-dependent oxidoreductase PA1648 Putative Zn-dependent oxidoreductase BA2113 Putative Zn-dependent oxidoreductase PA5234 Putative oxidoreductase SMc00968 Putative oxidoreductase YncB Quinone oxidoreductase (EC 1.6.5.5) YhdH, a putative quinone oxidoreductase Reductive_Dechlorination Tetrachloroethene reductive dehalogenase PceA (EC 1.97.1.8) Tetrachloroethene reductive dehalogenase PceA membrane-bound subunit Tetrachloroethene reductive dehalogenase TceA Tetrachloroethene reductive dehalogenase TceA membrane-bound subunit membrane docking protein Soluble_cytochromes_and_functionally_related_electron_carriers Cytochrome C550 (Soluble cytochrome C) Cytochrome C553 (soluble cytochrome f) Cytochrome c-552 precursor Cytochrome c2 Cytochrome c4 Cytochrome c551/c552 Cytochrome c552 Cytochrome c552 precursor (EC 1.7.2.2) Cytochrome c553 FIG135464: Cytochrome c4 Ferredoxin Ferredoxin, 2Fe-2S Membrane-attached cytochrome c550 Photosystem II protein PsbV, cytochrome c550 Probable cytochrome c-552 Probable cytochrome c2 Putative diheme cytochrome c-553 Soluble cytochrome b562 cytochrome c-551 soluble [2Fe-2S] ferredoxin 01 Secondary Metabolism 02 Aromatic amino acids and derivatives Cinnamic_Acid_Degradation 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase (EC 1.3.1.-) 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (EC 1.13.11.-) 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase (EC 3.7.1.-) 2-keto-4-pentenoate hydratase (EC 4.2.1.-) 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-) 3-phenylpropionate dioxygenase ferredoxin subunit 3-phenylpropionate dioxygenase ferredoxin--NAD(+) reductase component (EC 1.18.1.3) 3-phenylpropionate dioxygenase, alpha subunit (EC 1.14.12.19) 3-phenylpropionate dioxygenase, beta subunit (EC 1.14.12.19) 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) 4-hydroxybenzoate transporter Acetaldehyde dehydrogenase (EC 1.2.1.10) Hca operon (3-phenylpropionic acid catabolism) transcriptional activator HcaR Mhp operon transcriptional activator Probable 3-phenylpropionic acid transporter 02 Bacterial cytostatics, differentiation factors and antibiotics 2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone_and_other_bacterial_morphogens A-factor biosynthesis protein AfsA Acyl coenzyme A dehydrogenase, BldA, contributes to the proper timing of aerial mycelium formation and antibiotic production Inducers of aerial mycelium formation biosynthesis protein BldG Pleiotropic negative regulator for morphological and physiological development in Streptomyces, BldD Putative methyltransferase,bldM, influences various aspects of colony growth and development Clavulanic_acid_biosynthesis clavaldehyde dehydrogenase Nonribosomal_peptide_synthetases_(NRPS)_in_Frankia_sp._Ccl3 NRPS loading module Thr-PG-PG-Thr NRPS module 2 PG-PG-Asn NRPS module 3 PG-PG NRPS module 4 PG-Ser-Gly-Thr Paerucumarin_Biosynthesis HTH-type transcriptional regulator PtxR PvcA protein, related to known isonitrile synthases PvcB protein, related to amino acid oxidizing enzymes PvcC protein, related to two-component flavin adenine dinucleotide-dependent monooxygenases PvcD protein, related to two-component flavin adenine dinucleotide-dependent monooxygenases Phenazine_biosynthesis FAD-dependent monooxygenase PhzS Phenazine biosynthesis protein PhzA Phenazine biosynthesis protein PhzB Phenazine biosynthesis protein PhzC Phenazine biosynthesis protein PhzD Phenazine biosynthesis protein PhzE Phenazine biosynthesis protein PhzF Phenazine biosynthesis protein PhzG Phenazine modifying protein PhzH Phenazine-specific methyltransferase PhzM QscR quorum-sensing control repressor 02 Biologically active compounds in metazoan cell defence and differentiation Quinolinic_acid_and_its_derivatives 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) Quinolinate synthetase (EC 4.1.99.-) hydroxycinnamoyl-CoA: shikimate/quinate hydroxycinnamoyltransferase Steroid_sulfates Arylsulfatase (EC 3.1.6.1) Steryl-sulfatase precursor (EC 3.1.6.2) 02 Biosynthesis of phenylpropanoids Apigenin_derivatives Isoflavone reductase homolog P3 (EC 1.3.1.-) Biflavanoid_biosynthesis Dihydroflavonol-4-reductase (EC 1.1.1.219) Flavanone 4-reductase (EC 1.1.1.234) Flavanone-3-hydroxylase (EC 1.14.11.9) Flavanone-3-hydroxylase (EC 1.14.13.-) Flavanone-3-hydroxylase (EC 1.14.13.21) Flavone 7-O-beta-glucosyltransferase (EC 2.4.1.81) Luteolin O-methyltransferase (EC 2.1.1.42) Oxidoreductase (EC 1.3.-.-) Quercetin 3-O-methyltransferase 1 (EC 2.1.1.76) Caffeic_acid_derivatives 4-coumarate--CoA ligase 1 (EC 6.2.1.12) Caffeate 3,4-dioxygenase (EC1.13.11.22) Carboxy-lyase (EC 4.1.1.-) Cinnamoyl-CoA reductase (EC 1.2.1.44) Quinate O-hydroxy cinnamoyltransferase (EC 2.3.1.99) Flavanone_biosynthesis 4-coumarate--CoA ligase 1 (EC 6.2.1.12) Chalcone synthase (EC 2.3.1.74) Chalcone--flavonone isomerase (EC 5.5.1.6) Flavanone-3-hydroxylase (EC 1.14.11.9) trans-cinnamate 4-monooxygenase Lignine_biosynthesis 4-coumarate--CoA ligase 1 (EC 6.2.1.12) Cinnamoyl-CoA reductase (EC 1.2.1.44) Cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) Peroxidase precursor (EC 1.11.1.7) trans-cinnamate 4-monooxygenase Phenylpropanoids_general_biosynthesis 4-O-beta-D-glucoside hydrolase 4-coumarate--CoA ligase 1 (EC 6.2.1.12) Caffeic-o-methyltransferase (EC 2.1.1.68) Ferulate-5-hydroxylase Phenylpropanoid glycosiltransferases UDP-glucose:sinapate glucosyltransferase (EC 2.4.1.120) trans-cinnamate 4-monooxygenase Phenylpropionate_Degradation 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase (EC 1.3.1.-) 3-phenylpropionate dioxygenase ferredoxin subunit 3-phenylpropionate dioxygenase ferredoxin--NAD(+) reductase component (EC 1.18.1.3) 3-phenylpropionate dioxygenase, alpha subunit (EC 1.14.12.19) 3-phenylpropionate dioxygenase, beta subunit (EC 1.14.12.19) Phytoalexin_biosynthesis 4-coumarate--CoA ligase 1 (EC 6.2.1.12) 6-deoxychalcone synthase Diterpene cyclase Isoflavone reductase homolog P3 (EC 1.3.1.-) copalyl diphosphate synthase (CPS) (ent-kaurene synthetase A) flavonoid 7-O-methyltransferase (EC 2.1.1.75) sesquiterpene synthase-like protein trans-cinnamate 4-monooxygenase Phytosterol_biosynthesis 2,3-oxidosqualene:beta-amyrin cyclase (OS beta AC) (EC 5.4.99.-) 2-cys peroxiredoxin BAS1, chloroplast precursor Beta-amyrin synthase Oxidosqualene cyclase protein Pentacyclic triterpene synthase Salicylic_acid_biosynthesis1 6-Methyl salicylic acid synthase S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase-like protein Salicylic acid synthase Suberine_biosynthesis Cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) Fatty acid elongase 1 Fatty acid elongase-like protein Peroxidase precursor (EC 1.11.1.7) cinnamoyl-CoA:NADP+ oxidoreductase (E.C. 1.2.1.44) very-long-chain fatty acid condensing enzyme, putative Tannin_biosynthesis Anthocyanidin reductase Dihydroflavonol-4-reductase (EC 1.1.1.219) Leucoanthocyanidin dioxygenase (EC 1.14.11.19) 02 Lipid-derived mediators Cannabinoid_biosynthesis 2-AG hydrolase Cannabinoid receptor 1 Cannabinoid receptor 2 Fatty-acid amide hydrolase (EC 3.1.-.-) Monoglyceride lipase (EC 3.1.1.23) sn1-DAG lipases tetrahydrocannabinolic acid synthase 02 Plant Alkaloids Alkaloid_biosynthesis_from_L-lysine Deoxyhypusine synthase Oxalyl-CoA decarboxylase (EC 4.1.1.8) 02 Plant Hormones Auxin_biosynthesis Anthranilate phosphoribosyltransferase (EC 2.4.2.18) Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) Flavonol 3-sulfotransferase (EC 2.8.2.25) Indole glycerophosphate synthase Indole-3-acetate beta-glucosyltransferase Indole-3-pyruvate decarboxylase (EC 4.1.1.74) Indole-acetaldehyde dehydrogenase Indole-acetaldehyde reductase Indole-acetamide hydrolase Monoamine oxidase (1.4.3.4) Nitrilase 1 (EC 3.5.5.1) Nitrilase 2 (EC 3.5.5.1) Phosphoribosylanthranilate isomerase (EC 5.3.1.24) Putative AUX1-like permease Tryptophan synthase alpha chain (EC 4.2.1.20) Tryptophan synthase beta chain (EC 4.2.1.20) Tryptophan transaminase Tryptophol oxidase tryptophan monooxygenase Auxin_degradation L-ascorbate oxidase precursor (EC 1.10.3.3) Peroxidase (EC 1.11.1.7) Peroxidase precursor (EC 1.11.1.7) 02 Plant Octadecanoids Octadecanoids 12-oxophytodienoate reductase (OPR3)(DDE1) Allene oxide synthase, chloroplast precursor (EC 4.2.1.92) Allene-oxide cyclase Defective in anther DEHISCENCE1 Lipoxygenase (EC 1.13.11.12) Lipoxygenase, chloroplast precursor (EC 1.13.11.12) Oxidase Secretory low molecular weight phospholipase A2 alpha Secretory low molecular weight phospholipase A2 beta Secretory low molecular weight phospholipase A2 delta Secretory low molecular weight phospholipase A2 gamma 01 Stress Response 02 Acid stress Acid_resistance_mechanisms Arginine decarboxylase (EC 4.1.1.19) Arginine decarboxylase, catabolic (EC 4.1.1.19) Arginine/agmatine antiporter Biosynthetic arginine decarboxylase (EC 4.1.1.19) Glutamate decarboxylase (EC 4.1.1.15) Probable glutamate/gamma-aminobutyrate antiporter Glutamate_transporter_involved_in_acid_tolerance_in_Streptococcus Glutamate transport ATP-binding protein Glutamate transport membrane-spanning protein Glutamate transport permease protein Glutamate transport substrate-binding protein 02 Cold shock Cold_shock,_CspA_family_of_proteins Cold shock protein CspA Cold shock protein CspB Cold shock protein CspC Cold shock protein CspD Cold shock protein CspE Cold shock protein CspF Cold shock protein CspG Cold shock protein CspH Cold shock protein CspI 02 Dessication stress O-antigen_capsule_important_for_environmental_persistence Aldolase YihT Aldose-ketose isomerase YihS Alpha-glucosyltransferase YihQ DeoR-type transcriptional regulator YihW Glucuronide transport protein YihO Glucuronide transport protein YihP, homologous to YihO Outer membrane sugar transport protein YshA Oxidoreductase YihU Sugar kinase YihV Sugar-1-epimerase YihR 02 Detoxification D-tyrosyl-tRNA(Tyr)_deacylase D-tyrosyl-tRNA(Tyr) deacylase Glutathione-dependent_pathway_of_formaldehyde_detoxification Glutathione-dependent formaldehyde-activating enzyme (EC 4.4.1.22) S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) S-formylglutathione hydrolase (EC 3.1.2.12) Transcriptional regulator, LysR family, in formaldehyde detoxification operon Uncharacterized protein YaiN in in formaldehyde detoxification operon Tellurite_resistance:_Chromosomal_determinants FIG005189: putative transferase clustered with tellurite resistance proteins TehA/TehB Tellurite resistance protein TehA Tellurite resistance protein TehB Tellurite resistance protein TrgA Uncharacterized membrane lipoprotein clustered with tellurite resistance proteins TehA/TehB Uptake_of_selenate_and_selenite DedA protein Inner membrane transport protein YbaT Outer membrane porin protein NmpC precursor Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) TsgA protein homolog Various polyols ABC transporter, ATP-binding component Various polyols ABC transporter, periplasmic substrate-binding protein Various polyols ABC transporter, permease component 1 Various polyols ABC transporter, permease component 2 02 Heat shock Heat_shock_dnaK_gene_cluster_extended Chaperone protein DnaJ Chaperone protein DnaK DNA replication intiation control protein YabA FIG001341: Probable Fe(2+)-trafficking protein YggX FIG009886: phosphoesterase Glutathione synthetase (EC 6.3.2.3) Heat shock protein GrpE Heat-inducible transcription repressor HrcA HspR, transcriptional repressor of DnaK operon Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent MiaB family protein, possibly involved in tRNA or rRNA modification Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) Putative coproporphyrinogen III oxidase of BS HemN-type, oxygen-independent (EC 1.3.99.22), in heat shock gene cluster RNA polymerase sigma factor RpoH Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB Ribonuclease PH (EC 2.7.7.56) Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) Ribosomal protein L11 methyltransferase (EC 2.1.1.-) Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Signal peptidase-like protein Translation elongation factor LepA Xanthosine/inosine triphosphate pyrophosphatase rRNA small subunit methyltransferase I tmRNA-binding protein SmpB 02 Osmotic stress Betaine_biosynthesis_from_glycine Dimethylglycine N-methyltransferase Glycine N-methyltransferase (EC 2.1.1.20) Sarcosine N-methyltransferase Choline_and_Betaine_Uptake_and_Betaine_Biosynthesis Alcohol dehydrogenase GbsB (type III ), essential for the utilization of choline (EC 1.1.1.1) Betaine aldehyde dehydrogenase (EC 1.2.1.8) Choline ABC transport system, ATP-binding protein OpuBA Choline ABC transport system, choline-binding protein OpuBC Choline ABC transport system, permease protein OpuBB Choline ABC transport system, permease protein OpuBD Choline binding protein A Choline binding protein D Choline dehydrogenase (EC 1.1.99.1) Choline-sulfatase (EC 3.1.6.6) GbcA Glycine betaine demethylase subunit A GbcB Glycine betaine demethylase subunit B Glycine betaine ABC transport system permease protein Glycine betaine ABC transport system, ATP-binding protein OpuAA (EC 3.6.3.32) Glycine betaine ABC transport system, glycine betaine-binding protein OpuAC Glycine betaine ABC transport system, permease protein OpuAB Glycine betaine ABC transport system, permease/glycine betaine-binding protein OpuABC Glycine betaine transporter OpuD Glycine betaine/L-proline ABC transporter, glycine betaine/L-proline- binding/permease protein HTH-type transcriptional regulator BetI High-affinity choline uptake protein BetT L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1) L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) Osmotically activated L-carnitine/choline ABC transporter, ATP-binding protein OpuCA Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCB Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCD Osmotically activated L-carnitine/choline ABC transporter, substrate-binding protein OpuCC Sarcosine oxidase alpha subunit (EC 1.5.3.1) Sarcosine oxidase beta subunit (EC 1.5.3.1) Sarcosine oxidase delta subunit (EC 1.5.3.1) Sarcosine oxidase gamma subunit (EC 1.5.3.1) Ectoine_biosynthesis_and_regulation Aspartokinase (EC 2.7.2.4) associated with ectoine biosynthesis Diaminobutyrate-pyruvate aminotransferase (EC 2.6.1.46) Ectoine hydroxylase (EC 1.17.-.-) L-2,4-diaminobutyric acid acetyltransferase (EC 2.3.1.-) L-ectoine synthase (EC 4.2.1.-) Putative regulatory protein associated with the ectoine operon Osmoprotectant_ABC_transporter_YehZYXW_of_Enterobacteriales Osmoprotectant ABC transporter ATP-binding subunit YehX Osmoprotectant ABC transporter binding protein YehZ Osmoprotectant ABC transporter inner membrane protein YehW Osmoprotectant ABC transporter permease protein YehY Osmoregulation Aquaporin Z Glycerol uptake facilitator protein Osmotically inducible protein OsmY Outer membrane protein A precursor Propanediol diffusion facilitator Osmotic_stress_cluster Heat shock (predicted periplasmic) protein YciM, precursor Osmotically inducible lipoprotein B precursor Phosphatidylglycerophosphatase B (EC 3.1.3.27) Transcriptional regulatory protein YciT Synthesis_of_osmoregulated_periplasmic_glucans Beta-(1-->2)glucan export ATP-binding/permease protein NdvA (EC 3.6.3.42) Cyclic beta-1,2-glucan modification transmembrane protein Cyclic beta-1,2-glucan synthase (EC 2.4.1.-) Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) Glucans biosynthesis protein C (EC 2.1.-.-) Glucans biosynthesis protein D precursor Glucans biosynthesis protein G precursor OpgC protein Phosphoglycerol transferase I (EC 2.7.8.20) 02 Oxidative stress Glutaredoxins Competence protein F homolog, phosphoribosyltransferase domain Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) Glutaredoxin Glutaredoxin 1 Glutaredoxin 2 Glutaredoxin 3 Glutaredoxin 3 (Grx1) Glutaredoxin 3 (Grx2) Glutaredoxin 3 (Grx3) Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib Glutaredoxin-related protein Probable monothiol glutaredoxin GrlA Uncharacterized monothiol glutaredoxin ycf64-like Glutathione:_Biosynthesis_and_gamma-glutamyl_cycle 5-oxoprolinase (EC 3.5.2.9) Gamma-glutamyltranspeptidase (EC 2.3.2.2) Glutamate--cysteine ligase (EC 6.3.2.2) Glutamate--cysteine ligase (EC 6.3.2.2), divergent, of Alpha- and Beta-proteobacteria type Glutamate--cysteine ligase archaeal (EC 6.3.2.2) Glutathione biosynthesis bifunctional protein gshF (EC 6.3.2.2)(EC 6.3.2.3) Glutathione synthetase (EC 6.3.2.3) Predicted alternative glutathione synthetase (EC 6.3.2.3) Putative exported protein clustered with Gamma-glutamyltranspeptidase Similar to 5-oxoprolinase (EC 3.5.2.9) and Methylhydantoinases A, B (EC 3.5.2.14), contradiction in experimental data (see Annotation) Glutathione:_Non-redox_reactions Distant similarity with leukotriene C4 synthase (microsomal glutathione S-transferase) FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) Glutathione S-transferase (EC 2.5.1.18) Glutathione S-transferase family protein Glutathione S-transferase, Streptococcal type (EC 2.5.1.18) Glutathione S-transferase, alpha (EC 2.5.1.18) Glutathione S-transferase, delta (EC 2.5.1.18) Glutathione S-transferase, omega (EC 2.5.1.18) Glutathione S-transferase, phi (EC 2.5.1.18) Glutathione S-transferase, theta (EC 2.5.1.18) Glutathione S-transferase, unnamed subgroup (EC 2.5.1.18) Glutathione S-transferase, unnamed subgroup 2 (EC 2.5.1.18) Glutathione S-transferase, zeta (EC 2.5.1.18) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Lactoylglutathione lyase (EC 4.4.1.5) Phytochelatin synthase (EC 2.3.2.15), bacterial type Phytochelatin synthase (EC 2.3.2.15), eukaryotic type Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog Probable glutathione S-transferase (EC 2.5.1.18), YfcG homolog SAM-dependent methyltransferase 2, in cluster with Hydroxyacylglutathione hydrolase (EC 3.1.2.6) Similar to Hydroxyacylglutathione hydrolase, but in an organism lacking glutathione biosynthesis Uncharacterized GST-like protein yghU associated with glutathionylspermidine synthetase/amidase Uncharacterized GST-like protein yibF Uncharacterized GST-like protein yncG Uncharacterized glutathione S-transferase-like protein Glutathione:_Redox_cycle Glutaredoxin Glutaredoxin 1 Glutaredoxin 2 Glutaredoxin 3 Glutaredoxin 3 (Grx1) Glutaredoxin 3 (Grx2) Glutaredoxin 3 (Grx3) Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib Glutathione peroxidase (EC 1.11.1.9) Glutathione reductase (EC 1.8.1.7) Uncharacterized monothiol glutaredoxin ycf64-like Glutathione_analogs:_mycothiol Acetyl-CoA:Cys-GlcN-Ins acetyltransferase, mycothiol synthase MshD Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent (EC 1.2.1.66) Glycosyltransferase MshA involved in mycothiol biosynthesis (EC 2.4.1.-) L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC Maleylpyruvate isomerase, mycothiol-dependent (EC 5.2.1.4) Mycothiol S-conjugate amidase Mca N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB NADPH-dependent mycothiol reductase Mtr Putative hydrolase in cluster with formaldehyde/S-nitrosomycothiol reductase MscR S-nitrosomycothiol reductase MscR Uncharacterized protein Rv0487/MT0505 clustered with mycothiol biosynthesis gene Glutathionylspermidine_and_Trypanothione Glutathionylspermidine amidohydrolase (EC 3.5.1.78) Glutathionylspermidine synthase (EC 6.3.1.8) Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1 Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 2 Uncharacterized GST-like protein yghU associated with glutathionylspermidine synthetase/amidase Oxidative_stress Alkyl hydroperoxide reductase subunit C-like protein Catalase (EC 1.11.1.6) DNA binding protein starved cells-like peroxide resistance protein Fe2+/Zn2+ uptake regulation proteins Ferric uptake regulation protein Ferric uptake regulation protein FUR Ferroxidase (EC 1.16.3.1) Fumarate and nitrate reduction regulatory protein Heme oxygenase HemO, associated with heme uptake Hydrogen peroxide-inducible genes activator Iron-binding ferritin-like antioxidant protein Iron-responsive regulator Irr Manganese superoxide dismutase (EC 1.15.1.1) Metallothionein Nitrite-sensitive transcriptional repressor NsrR NnrS protein involved in response to NO Non-specific DNA-binding protein Dps Organic hydroperoxide resistance protein Organic hydroperoxide resistance transcriptional regulator Paraquat-inducible protein A Paraquat-inducible protein B Peroxidase (EC 1.11.1.7) Peroxidase/catalase HPI (EC 1.11.1.6) Peroxide stress regulator Peroxide stress regulator PerR, FUR family Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-) Probable peroxiredoxin (EC 1.11.1.15) Redox-sensitive transcriptional activator SoxR Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein) Regulatory protein SoxS Rubrerythrin Superoxide dismutase (EC 1.15.1.1) Superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) Superoxide dismutase [Fe] (EC 1.15.1.1) Superoxide dismutase [Mn/Fe] (EC 1.15.1.1) Superoxide dismutase [Mn] (EC 1.15.1.1) Superoxide reductase (EC 1.15.1.2) Thioredoxin peroxidase 1 (EC 1.6.4.-) Transcriptional regulator, Crp/Fnr family Transcriptional regulator, FUR family Zinc uptake regulation protein ZUR bacteriophytochrome heme oxygenase BphO superoxide dismutase [Fe-Zn] (EC 1.15.1.1) transcriptional regulator, Crp/Fnr family transcriptional regulator, Fur family Protection_from_Reactive_Oxygen_Species Catalase (EC 1.11.1.6) Cytochrome c551 peroxidase (EC 1.11.1.5) Manganese superoxide dismutase (EC 1.15.1.1) Peroxidase (EC 1.11.1.7) Superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) Superoxide dismutase [Fe] (EC 1.15.1.1) Redox-dependent_regulation_of_nucleus_processes Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH) NAD-dependent deacetylase NAD-dependent deacetylase (EC 3.5.1.-) NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) NAD-dependent protein deacetylase of SIR2 family NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) Nicotinamidase (EC 3.5.1.19) Nicotinate phosphoribosyltransferase (EC 2.4.2.11) Poly [ADP-ribose] polymerase-1 (EC 2.4.2.30) Regulation_of_Oxidative_Stress_Response Aerobic respiration control protein arcA Aerobic respiration control sensor protein arcB (EC 2.7.3.-) Catalase HPII (EC 1.11.1.6) DNA protection during starvation protein Oxidative stress regulatory protein Oxidative stress transcriptional regulator (responsive to S-nitrosothiols) Peroxidase (EC 1.11.1.7) Peroxide stress regulator RNA polymerase sigma factor Redox-sensitive transcriptional activator SoxR Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) Superoxide dismutase [Fe] (EC 1.15.1.1) Superoxide dismutase [Mn] (EC 1.15.1.1) antisense RNA diphtheria toxin repressor ferric uptake regulator fumarate/nitrate reduction regulatory protein outermembrane protein F regulation of superoxide response regulon transcriptional repressor of znuABC operon Rubrerythrin Alkyl hydroperoxide reductase subunit C-like protein Fe-S oxidoreductase-like protein in Rubrerythrin cluster Hypothetical protein i Rubrerythrin cluster Probable peroxiredoxin (EC 1.11.1.15) Rubredoxin Rubredoxin-NAD(+) reductase (EC 1.18.1.1) Rubrerythrin Superoxide reductase (EC 1.15.1.2) rubredoxin-oxygen oxidoreductase 02 Periplasmic Stress Periplasmic_Acid_Stress_Response_in_Enterobacteria Chaperone HdeA Chaperone HdeB Membrane transporter HdeD, H-NS repressed Putative membrane transporter ATPase,YhiD Transcriptional activator GadE Periplasmic_Stress_Response HtrA protease/chaperone protein Membrane-associated zinc metalloprotease Outer membrane protein H precursor Outer membrane stress sensor protease DegQ, serine protease Outer membrane stress sensor protease DegS Sigma factor RpoE negative regulatory protein RseA Sigma factor RpoE negative regulatory protein RseB precursor Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) 02 Bacterial_hemoglobins Cyanoglobin Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) Hemoglobin-like protein HbO Hypothetical protein in Cyanoglobin locus Protein containing plastocyanin/azurin family domain Putative bacterial haemoglobin diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Carbon_Starvation Carbon starvation protein A Carbon starvation protein A paralog Carbon storage regulator Starvation lipoprotein Slp Starvation lipoprotein Slp paralog Starvation sensing protein RspA Starvation sensing protein RspB Stringent starvation protein A Stringent starvation protein B Commensurate_regulon_activation Multiple antibiotic resistance protein MarA Regulatory protein SoxS Right origin-binding protein Transcriptional activator RamA Transcriptional regulator YkgA Dimethylarginine_metabolism NG,NG-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18) Ornithine aminotransferase (EC 2.6.1.13) Protein arginine N-methyltransferase 1 (EC 2.1.1.-) protein arginine methyltransferase type 2 (SDMA formation) Flavohaemoglobin 3-phenylpropionate dioxygenase, alpha subunit (EC 1.14.12.19) 3-phenylpropionate dioxygenase, beta subunit (EC 1.14.12.19) ABC-type Fe3+-siderophore transport system, permease 2 component Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent Hfl_operon GTP-binding protein HflX GTP-binding protein related to HflX HflC protein HflK protein Putative inner membrane protein YjeT (clustered with HflC) RNA-binding protein Hfq Phage_shock_protein_(psp)_operon Phage shock protein A Phage shock protein B Phage shock protein C Phage shock protein D Phage shock protein E Phage shock protein E precursor Psp operon transcriptional activator SigmaB_stress_responce_regulation Putative SigmaB asociated two-component system sensor protein RNA polymerase sigma factor SigB RsbR, positive regulator of sigma-B RsbS, negative regulator of sigma-B Serine phosphatase RsbU, regulator of sigma subunit Serine-protein kinase rsbW (EC 2.7.11.1) anti sigma b factor antagonist RsbV anti-sigma B factor RsbT Sugar-phosphate_stress_regulation SgrR, sugar-phosphate stress, transcriptional activator of SgrS small RNA Universal_stress_protein_family Universal stress protein A Universal stress protein B Universal stress protein C Universal stress protein D Universal stress protein E Universal stress protein F Universal stress protein G Universal stress protein family Universal stress protein family 1 Universal stress protein family 2 Universal stress protein family 3 Universal stress protein family 4 Universal stress protein family 5 Universal stress protein family 6 Universal stress protein family 7 Universal stress protein family 8 Universal stress protein family COG0589 01 Sulfur Metabolism 02 Inorganic sulfur assimilation Inorganic_Sulfur_Assimilation 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) 4Fe-4S ferredoxin, iron-sulfur binding ABC-type probable sulfate transporter, ATPase component ABC-type probable sulfate transporter, periplasmic binding protein ABC-type probable sulfate transporter, permease protein Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) Adenylylsulfate kinase (EC 2.7.1.25) Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) Conserved hypothetical protein probably involved in assimilatory sulfate reduction Conserved hypothetical protein probably involved in sulfate reduction Ferredoxin Ferredoxin--NADP(+) reductase (EC 1.18.1.2) Ferredoxin--NADP(+) reductase, actinobacterial (eukaryote-like) type (EC 1.18.1.2) Ferredoxin--sulfite reductase (EC 1.8.7.1) Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) Ferredoxin--sulfite reductase, bacillial type (EC 1.8.7.1) Ferredoxin-like protein involved in electron transfer Oxidoreductase probably involved in sulfite reduction Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) Putative sulfate permease Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) Sulfate and thiosulfate binding protein CysP Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) Sulfate permease, Pit-type Sulfate permease, Trk-type Sulfate transport system permease protein CysT Sulfate transport system permease protein CysW Sulfate transporter, CysZ-type Sulfate-binding protein Sbp Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2) Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) 02 Organic sulfur assimilation Alkanesulfonate_assimilation ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component ABC-type nitrate/sulfonate/bicarbonate transport system, permease component ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Alkanesulfonate monooxygenase (EC 1.14.14.5) Alkanesulfonates ABC transporter ATP-binding protein Alkanesulfonates transport system permease protein Alkanesulfonates-binding protein Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) Arylsulfatase (EC 3.1.6.1) Dibenzothiophene desulfurization enzyme B FMN reductase (EC 1.5.1.29) Organosulfonate utilization protein SsuF Putative alkylsulfatase (EC 1.14.11.17) Putative arylsulfatase regulatory protein Sulfate ester binding protein probable dibenzothiophene desulfurization enzyme sulfonate monooxygenase Alkanesulfonates_Utilization Alkanesulfonate monooxygenase (EC 1.14.14.5) Alkanesulfonates ABC transporter ATP-binding protein Alkanesulfonates transport system permease protein Alkanesulfonates-binding protein FMN reductase (EC 1.5.1.29) DMSP_breakdown DMSP breakdown hydrolase protein DMSP demethylase (DmdA) (EC 2.1.2.10) L-Cystine_Uptake_and_Metabolism Bacterial luciferase family protein YtmO, in cluster with L-cystine ABC transporter Cystathionine beta-lyase (EC 4.4.1.8) Cystathionine gamma-synthase (EC 2.5.1.48) Cystine ABC transporter, ATP-binding protein Cystine ABC transporter, periplasmic cystine-binding protein FliY Cystine ABC transporter, permease protein HTH-type transcriptional regulator YtlI, LysR family L-Cystine ABC transporter, ATP-binding protein TcyC L-Cystine ABC transporter, ATP-binding protein TcyN L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA L-Cystine ABC transporter, periplasmic cystine-binding protein TcyJ L-Cystine ABC transporter, periplasmic cystine-binding protein TcyK L-Cystine ABC transporter, permease protein TcyB L-Cystine ABC transporter, permease protein TcyL L-Cystine ABC transporter, permease protein TcyM L-cystine uptake protein TcyP Taurine_Utilization Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) Taurine transport ATP-binding protein TauB Taurine transport system permease protein TauC Taurine transporter substrate-binding protein Taurine-binding periplasmic protein TauA Utilization_of_glutathione_as_a_sulphur_source Gamma-glutamyltranspeptidase (EC 2.3.2.2) Putative glutathione transporter, ATP-binding component Putative glutathione transporter, permease component Putative glutathione transporter,solute-binding component Putative gluthatione transporter,solute-binding component 02 Dimethylsulfoniopropionate_(DMSP)_mineralization 3-methylmercaptopropionyl-CoA dehydrogenase (DmdC) 3-methylmercaptopropionyl-CoA ligase (DmdB) 3-methylthioacryloyl-CoA hydratase (DmdD) DMSP demethylase (DmdA) (EC 2.1.2.10) Methylthioacryloyl-CoA hydratase 2 Galactosylceramide_and_Sulfatide_metabolism Alpha-galactosidase (EC 3.2.1.22) Alpha-galactosidase precursor (EC 3.2.1.22) Arylsulfatase (EC 3.1.6.1) Beta-galactosidase (EC 3.2.1.23) Beta-galactosidase 3 Beta-galactosidase large subunit (EC 3.2.1.23) Beta-galactosidase small subunit (EC 3.2.1.23) Galactocerebrosidase precursor (EC 3.2.1.46) Neuraminidase NanP Sialidase (EC 3.2.1.18) probable beta-D-galactosidase Release_of_Dimethyl_Sulfide_(DMS)_from_Dimethylsulfoniopropionate_(DMSP) Dimethylsulfoniopropionate (DMSP) acyl CoA transferase DddD Dimethylsulfoniopropionate (DSMP) lyase DddL Sulfate_reduction-associated_complexes Protein similar to glutamate synthase [NADPH] small chain, clustered with sulfite reductase Sulfite reductase alpha subunit (EC 1.8.99.1) Sulfite reductase beta subunit (EC 1.8.99.1) Sulfite reductase, dissimilatory-type gamma subunit (EC 1.8.99.3) Sulfite reduction-associated complex DsrMKJOP iron-sulfur protein DsrO (=HmeA) Sulfite reduction-associated complex DsrMKJOP multiheme protein DsrJ (=HmeF) Sulfite reduction-associated complex DsrMKJOP protein DsrK (=HmeD) Sulfite reduction-associated complex DsrMKJOP protein DsrM (= HmeC) Sulfite reduction-associated complex DsrMKJOP protein DsrP (= HmeB) tRNA 2-thiouridine synthesizing protein E (EC 2.8.1.-) Sulfur_oxidation Blr3520 protein homolog, hypothetical protein Cytochrome c-type biogenesis protein CcdA (DsbD analog) Lipocalin-related protein and Bos/Can/Equ allergen Regulatory protein SoxS SoxH protein, homolog Sulfide dehydrogenase [flavocytochrome C] flavoprotein chain precursor (EC 1.8.2.-) Sulfite dehydrogenase cytochrome subunit SoxD Sulfite oxidase Sulfur oxidation molybdopterin C protein Sulfur oxidation protein SoxB Sulfur oxidation protein SoxX Sulfur oxidation protein SoxY Sulfur oxidation protein SoxZ Thiol:disulfide interchange protein, thioredoxin family cytochrome c subunit of flavocytochrome c sulfide dehydrogenase sulfur oxidation protein SoxA thioredoxin SoxW transcriptional regulator SoxR Thioredoxin-disulfide_reductase Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) Alkyl hydroperoxide reductase protein F (EC 1.6.4.-) Alkyl hydroperoxide reductase subunit C-like protein Alkylhydroperoxidase protein D Hydrogen peroxide-inducible genes activator Thiol peroxidase, Bcp-type (EC 1.11.1.15) Thiol peroxidase, Tpx-type (EC 1.11.1.15) Thioredoxin reductase (EC 1.8.1.9) 01 Virulence 02 Adhesion Type_1_pili_(mannose-sensitive_fimbriae) chaperone FimC mannose-specific adhesin FimH type 1 fimbrae adaptor subunit FimF type 1 fimbrae adaptor subunit FimG type 1 fimbriae anchoring protein FimD type 1 fimbriae major subunit FimA type 1 fimbriae protein FimI, unknown function type 1 fimbriae regulatory protein FimB type 1 fimbriae regulatory protein FimE 02 Fimbriae of the Chaperone/Usher Assembly Pathway α-Fimbriae Alpha-fimbriae chaperone protein Alpha-fimbriae major subunit Alpha-fimbriae tip adhesin Alpha-fimbriae usher protein α-related_Fimbriae_in_Yersinia Alpha-related fimbriae chaperone 1 Alpha-related fimbriae chaperone 2 Alpha-related fimbriae major subunit Alpha-related fimbriae minor subunit 1 Alpha-related fimbriae minor subunit 2 Alpha-related fimbriae usher protein β-Fimbriae Beta-fimbriae chaperone protein Beta-fimbriae probable major subunit Beta-fimbriae usher protein κ-Fimbriae Kappa-fimbriae chaperone protein Kappa-fimbriae major subunit Kappa-fimbriae probable subunit Kappa-fimbriae regulatory protein Kappa-fimbriae usher protein σ-Fimbriae Sigma-fimbriae chaperone protein Sigma-fimbriae tip adhesin Sigma-fimbriae uncharacterized paralogous subunit Sigma-fimbriae uncharacterized subunit Sigma-fimbriae usher protein 02 Quorum sensing and biofilm formation Acyl_Homoserine_Lactone_(AHL)_Autoinducer_Quorum_Sensing_ Autoinducer synthase BpsI Autoinducer synthase LuxI-type Autoinducer synthesis protein LuxI Autoinducer synthesis protein SolI Autoinducer-binding transcriptional regulator BpsR Autoinducer-binding transcriptional regulator LuxR-type FIG005933: hypothetical protein N-acyl-L-homoserine lactone synthetase LasI N-acyl-L-homoserine lactone synthetase RhlL N-acyl-L-homoserine lactone synthetase TraI Transcriptional activator protein LuxR Transcriptional activator protein solR Transcriptional regulator LasR Transcriptional regulator RhlR hypothetical protein clustered with LuxR 02 Resistance to antibiotics and toxic compounds BlaR1_Family_Regulatory_Sensor-transducer_Disambiguation Beta-lactamase (EC 3.5.2.6) Beta-lactamase class A Beta-lactamase regulatory sensor-transducer BlaR1 Beta-lactamase repressor BlaI Copper-translocating P-type ATPase (EC 3.6.3.4) Methicillin resistance regulatory sensor-transducer MecR1 Methicillin resistance regulatory sensor-transducer MecR1, truncated Methicillin resistance repressor MecI Negative transcriptional regulator-copper transport operon Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase Peptidase M48, Ste24p precursor Probable beta-lactamase ybxI precursor (EC 3.5.2.6) Regulatory protein BlaR1 Regulatory sensor-transducer, BlaR1/MecR1 family Transcriptional regulator, MecI family Transcriptional repressor, BlaI/MecI family Erythromycin_resistance Dimethyladenosine transferase (EC 2.1.1.-) rRNA adenine N-6-methyltransferase (EC 2.1.1.48) rRNA adenine N-6-methyltransferase (EC 2.1.1.48) (Macrolide-lincosamide-streptogramin B resistance protein) (Erythromycin resistance protein) rRNA adenine N-6-methyltransferase (erm/ksgA) Polymyxin_Synthetase_Gene_Cluster_in_Bacillus 4'-phosphopantetheinyl transferase (EC 2.7.8.-) in polymyxin biosynthetic cluster Polymyxin synthetase PmxA Polymyxin synthetase PmxB Polymyxin transporter PmxC Uncharacterized protein in polymyxin biosynthetic cluster 02 Toxins and superantigens Diphtheria_toxin diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1 Streptococcus_agalactiae_hemolysin_operon AcpC Beta hemolysin CylE CylA CylB CylD CylF CylG CylH CylI CylJ CylX CylZ 02 Type III, Type IV, Type VI, ESAT secretion systems Type_4_secretion_and_conjugative_transfer ATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB11) ATPase provides energy for both assembly of type IV secretion complex and secretion of T-DNA complex (VirB4) Bores hole in peptidoglycan layer allowing type IV secretion complex assembly to occur (VirB1) Conjugative signal peptidase TrhF Conjugative transfer entry exclusion protein TrbK Conjugative transfer protein ELI_00880 Conjugative transfer protein ELI_04330 Conjugative transfer protein PSLT087 Conjugative transfer protein PSLT093 Conjugative transfer protein TrbA Conjugative transfer protein TrbB Conjugative transfer protein TrbC Conjugative transfer protein TrbD Conjugative transfer protein TrbE Conjugative transfer protein TrbF Conjugative transfer protein TrbG Conjugative transfer protein TrbH Conjugative transfer protein TrbI Conjugative transfer protein TrbJ Conjugative transfer protein TrbL Conjugative transfer protein TrbN Conjugative transfer protein TrbO Conjugative transfer protein TrbP (IncF TraX homolog) Conjugative transfer protein s043 Forms the bulk of type IV secretion complex that spans outer membrane and periplasm (VirB9) IncF plasmid conjugative transfer DNA-nicking and unwinding protein TraI IncF plasmid conjugative transfer fertility inhibition protein FinO IncF plasmid conjugative transfer mating signal transduction protein TraM IncF plasmid conjugative transfer pilin acetylase TraX IncF plasmid conjugative transfer pilin protein TraA IncF plasmid conjugative transfer pilus assembly protein TraB IncF plasmid conjugative transfer pilus assembly protein TraC IncF plasmid conjugative transfer pilus assembly protein TraE IncF plasmid conjugative transfer pilus assembly protein TraF IncF plasmid conjugative transfer pilus assembly protein TraH IncF plasmid conjugative transfer pilus assembly protein TraK IncF plasmid conjugative transfer pilus assembly protein TraL IncF plasmid conjugative transfer pilus assembly protein TraU IncF plasmid conjugative transfer pilus assembly protein TraV IncF plasmid conjugative transfer pilus assembly protein TraW IncF plasmid conjugative transfer protein TraD IncF plasmid conjugative transfer protein TraG IncF plasmid conjugative transfer protein TraN IncF plasmid conjugative transfer protein TraP IncF plasmid conjugative transfer protein TraQ IncF plasmid conjugative transfer protein TraR IncF plasmid conjugative transfer protein TrbA IncF plasmid conjugative transfer protein TrbB IncF plasmid conjugative transfer protein TrbC IncF plasmid conjugative transfer protein TrbD IncF plasmid conjugative transfer protein TrbE IncF plasmid conjugative transfer protein TrbF IncF plasmid conjugative transfer protein TrbG IncF plasmid conjugative transfer protein TrbH IncF plasmid conjugative transfer protein TrbI IncF plasmid conjugative transfer protein TrbJ IncF plasmid conjugative transfer regulator TraJ IncF plasmid conjugative transfer regulator TraY IncF plasmid conjugative transfer surface exclusion protein TraS IncF plasmid conjugative transfer surface exclusion protein TraT IncN plasmid KikA protein IncQ plasmid conjugative transfer DNA nicking endonuclease TraR (pTi VirD2 homolog) IncQ plasmid conjugative transfer DNA primase TraO (pTi TraA homolog) IncQ plasmid conjugative transfer protein TraB IncQ plasmid conjugative transfer protein TraG IncQ plasmid conjugative transfer protein TraP IncQ plasmid conjugative transfer protein TraQ (RP4 TrbM homolog) IncW plasmid conjugative protein TrwB (TraD homolog) IncW plasmid conjugative relaxase protein TrwC (TraI homolog) Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB10) Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB3) Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB8) Integral inner membrane protein of type IV secretion complex (VirB6) Lipoprotein of type IV secretion complex that spans outer membrane and periplasm (VirB7) Major pilus subunit of type IV secretion complex (VirB2) Minor pilin of type IV secretion complex (VirB5) Two-component regulator of vir regulon. VirA is a transmembrane histidine kinase Type IV secretion system protein VirD4 YhfA Protein in tra region of some IncF plasmids Ync Ynd 02 Streptococcus_agalactiae_virulome Capsular polysaccharide biosynthesis protein CpsK(V) Capsular polysaccharide biosythesis protein CpsI Capsular polysaccharide repeat unit transporter CpsL Capsular polysaccharide repeating-unit polymerase CpsH CspA protein Exopolysaccharide biosynthesis transcriptional activator EpsA Extracellular hemolysin Fibrinogen-binding protein A Fibrinogen-binding protein B Galactosyl transferase CpsE (EC 2.7.8.-) Glycosyl transferase CpsG Hemolysin III Hyaluronate lyase Lmb protein N-acetylneuraminate synthase (EC 2.5.1.56) Polysaccharide biosynthesis glycosyl transferase CpsJ Polysaccharide biosynthesis protein CpsF Streptokinase B Tyrosine-protein kinase EpsD (EC 2.7.10.2) Tyrosine-protein kinase transmembrane modulator EpsC Tyrosine-protein phosphatase CpsB (EC 3.1.3.48) UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) 01 Virulence, Disease and Defense 02 Adhesion Accessory_colonization_factor Accessory colonization factor AcfA Accessory colonization factor AcfB Accessory colonization factor AcfC Accessory colonization factor AcfD precursor Adhesins_in_Staphylococcus Accumulation-associated protein AAP Adhesin of unknown specificity SdrC Adhesin of unknown specificity SdrD Adhesin of unknown specificity SdrE, similar to bone sialoprotein-binding protein Bbp Antiadhesin Pls, binding to squamous nasal epithelial cells Bifunctional autolysin Atl Clumping factor ClfA, fibrinogen-binding protein Clumping factor ClfB, fibrinogen binding protein Collagen binding protein Cna Elastin binding protein EbpS Extracellular ECM and plasma binding protein Emp Extracellular adherence protein of broad specificity Eap/Map Extracellular fibrinogen-binding protein Efb Fibronectin binding protein FnbA Fibronectin binding protein FnbB Hypothetical protein, similarity with fibrinogen-binding protein Efb Hypothetical protein, similarity with von Willebrand factor-binding VWbp Predicted cell-wall-anchored protein SasA (LPXTG motif) Predicted cell-wall-anchored protein SasC (LPXTG motif) Predicted cell-wall-anchored protein SasD (LPXAG motif) Predicted cell-wall-anchored protein SasF (LPXAG motif) Predicted cell-wall-anchored protein SasK (LPXTG motif) Protein A, von Willebrand factor binding protein Spa Secreted von Willebrand factor-binding protein VWbp Staphylocoagulase Virulence-associated cell-wall-anchored protein SasG (LPXTG motif), binding to squamous nasal epithelial cells Virulence-associated cell-wall-anchored protein SasH (LPXTG motif) Adhesion_of_Campylobacter Amino-acid ABC transporter ATP-binding protein PebC Fibronectin/fibrinogen-binding protein Filamentous haemagglutinin domain protein Flagellin C Major cell-binding factor precursor PebA Outer membrane fibronectin-binding protein Putative ABC-type amino-acid transporter permease protein Putative fibronectin domain-containing lipoprotein Surface-exposed lipoprotein JlpA Decorin_binding_proteins_of_Borrelia Decorin binding protein A Decorin binding protein B Mediator_of_hyperadherence_YidE_in_Enterobacteria_and_its_conserved_region 16 kDa heat shock protein A 16 kDa heat shock protein B HTH-type transcriptional regulator YidP Mediator of hyperadherence YidE Outer membrane lipoprotein YidQ Uncharacterized protein YidR Uncharacterized protein YidS Streptococcus_pyogenes_recombinatorial_zone Chaperonin (heat shock protein 33) Collagen-binding adhesin Fibronectin-binding protein Fibronectin-binding protein 2 Multiple sugar metabolism regulator Negative transcriptional regulator Serum opacity factor Signal peptidase I Sortase Transcriptional regulator, RofA 02 Bacteriocins, ribosomally synthesized antibacterial peptides Bacitracin_Stress_Response ABC transporter ATP-binding protein YvcR ABC transporter permease protein YvcS Bacitracin export ATP-binding protein BceA Bacitracin export permease protein BceB Conserved protein LiaG in B. subtilis in Lia cluster Protein LiaH, similar to phage shock protein A Protein LiaI Response regulator LiaR Sensor histidine kinase LiaS Transporter LiaF Two-component response regulator BceR Two-component response regulator YvcP Two-component sensor histidine kinase BceS Two-component sensor kinase YvcQ Bacteriocin-like_peptides_Blp Bacteriocin immunity protein BlpL Bacteriocin-like peptide I BlpI Bacteriocin-like peptide J BlpJ Bacteriocin-like peptide M BlpM Bacteriocin-like peptide N BlpN Bacteriocin-like peptide O BlpO Bacterocin transport accessory protein Bactriocin immunity protein BlpX Bactriocin immunity protein BlpY BlpT protein, fusion BlpZ protein, fusion Lactacin F ABC transporter permease component Lactacin F immunity protein Lactacin F transporter auxillary protein Lactacin F two-component system response regulator Lactacin F two-component system sensor histidine kinase Marinocine,_a_broad-spectrum_antibacterial_protein Dehydrogenase flavoprotein LodB Lysine-epsilon oxidase (EC 1.4.3.20) antimicrobial protein LodA Tolerance_to_colicin_E2 Conserved uncharacterized protein CreA Inner membrane protein CreD Inner membrane protein CreD-like protein Two-component response regulator CreB Two-component response regulator CreC 02 Detection MLST Acetyl-CoA acetyltransferase (EC 2.3.1.9) Carbamate kinase (EC 2.7.2.2) Glycerol kinase (EC 2.7.1.30) Guanylate kinase (EC 2.7.4.8) Phosphate acetyltransferase (EC 2.3.1.8) Shikimate 5-dehydrogenase (EC 1.1.1.25) Triosephosphate isomerase (EC 5.3.1.1) 02 Invasion and intracellular resistance Cytolysin_and_Lipase_operon_in_Vibrio Cytolysin and hemolysin, HlyA, Pore-forming toxin Lipase activator protein, Lipase-specific foldase Lipase precursor (EC 3.1.1.3) Metalloprotease, putative zinc-binding domain Methyl-accepting chemotaxis protein, hemolysin secretion protein HylB Gram-Positive_Extracellular_Nucleases DNA-entry nuclease (Competence-specific nuclease) (EC 3.1.30.-) Streptococcal extracellular nuclease 2 Streptococcal extracellular nuclease 3 Streptococcal extracellular nuclease 4 Streptodornase B Streptodornase D Listeria_surface_proteins:_Internalin-like_proteins Internalin A (LPXTG motif) Internalin B (GW modules) Internalin C Internalin C2 (LPXTG motif) Internalin D (LPXTG motif) Internalin E (LPXTG motif) Internalin G (LPXTG motif) Internalin H (LPXTG motif) Internalin-like protein (LPXTG motif) Lin0290 homolog Internalin-like protein (LPXTG motif) Lin0372 homolog Internalin-like protein (LPXTG motif) Lin0661 homolog Internalin-like protein (LPXTG motif) Lin0739 homolog Internalin-like protein (LPXTG motif) Lin0740 homolog Internalin-like protein (LPXTG motif) Lin1204 homolog Internalin-like protein (LPXTG motif) Lmo0171 homolog Internalin-like protein (LPXTG motif) Lmo0327 homolog Internalin-like protein (LPXTG motif) Lmo0331 homolog Internalin-like protein (LPXTG motif) Lmo0333 homolog Internalin-like protein (LPXTG motif) Lmo0409 homolog Internalin-like protein (LPXTG motif) Lmo0514 homolog Internalin-like protein (LPXTG motif) Lmo0610 homolog Internalin-like protein (LPXTG motif) Lmo0732 homolog Internalin-like protein (LPXTG motif) Lmo0801 homolog Internalin-like protein (LPXTG motif) Lmo1136 homolog Internalin-like protein (LPXTG motif) Lmo1289 homolog Internalin-like protein (LPXTG motif) Lmo1290 homolog Internalin-like protein (LPXTG motif) Lmo2026 homolog Internalin-like protein (LPXTG motif) Lmo2396 homolog Internalin-like protein (LPXTG motif) Lmo2821 homolog Internalin-like protein (LPXTG motif) Lmof0365 homolog Internalin-like protein Lin0295 homolog Internalin-like protein Lin2537 homolog Internalin-like protein Lmo0549 homolog Internalin-like protein Lmo2027 homolog Internalin-like protein Lmo2445 homolog Internalin-like protein Lmo2470 homolog internalin, putative internalin, putative (LPXTG motif) Listeria_surface_proteins:_LPXTG_motif Putative peptidoglycan bound protein (LPXTG motif) LMOf2365_1974 homolog Putative peptidoglycan bound protein (LPXTG motif) Lin2281 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0159 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0160 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0175 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0320 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0463 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0550 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0627 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0835 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0842 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo0880 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo1413 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo1666 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo1799 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo2085 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo2178 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo2179 homolog Putative peptidoglycan bound protein (LPXTG motif) Lmo2714 homolog Sortase Salmonella_invasion_locus Cell invasion protein SipD (Salmonella invasion protein D) Cell invasion protein sipC (Effector protein SipC) Chaperone protein SicA (Salmonella invasin chaperone) Invasion protein InvA Invasion protein InvE Probable ATP synthase SpaL (EC 3.6.3.14) (Invasion protein InvC) Protein InvG precursor Surface presentation of antigens protein SpaK (Invasion protein InvB) Surface presentation of antigens protein SpaM Surface presentation of antigens protein SpaN (Invasion protein InvJ) Surface presentation of antigens protein SpaO Surface presentation of antigens protein SpaP Surface presentation of antigens protein SpaQ Surface presentation of antigens protein SpaR Surface presentation of antigens protein SpaS cell invasion protein SipB 02 Resistance to antibiotics and toxic compounds Adaptation_to_d-cysteine Cystine ABC transporter, ATP-binding protein Cystine ABC transporter, permease protein D-cysteine desulfhydrase (EC 4.4.1.15) L-Cystine ABC transporter, periplasmic cystine-binding protein Aminoglycoside_adenylyltransferases Aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) Spectinomycin 9-O-adenylyltransferase Streptomycin 3''-O-adenylyltransferase (EC 2.7.7.47) Arsenic_resistance Arsenate reductase (EC 1.20.4.1) Arsenic efflux pump protein Arsenic resistance protein ArsH Arsenical pump-driving ATPase (EC 3.6.3.16) Arsenical resistance operon repressor Arsenical resistance operon trans-acting repressor ArsD Arsenical-resistance protein ACR3 Beta-lactamase Beta-lactamase Beta-lactamase (Cephalosporinase) (EC 3.5.2.6) Beta-lactamase (EC 3.5.2.6) Beta-lactamase AmpS Beta-lactamase CTX-M-16 Beta-lactamase PSE-2 precursor (EC 3.5.2.6) Beta-lactamase class A Beta-lactamase class C and other penicillin binding proteins Beta-lactamase class D Beta-lactamase repressor BlaI Metal-dependent hydrolases of the beta-lactamase superfamily I Metal-dependent hydrolases of the beta-lactamase superfamily II Metal-dependent hydrolases of the beta-lactamase superfamily III Negative regulator of beta-lactamase expression Probable beta-lactamase ybxI precursor (EC 3.5.2.6) Regulatory protein BlaR1 Cadmium_resistance Cadmium efflux system accessory protein Cadmium resistance protein Cadmium-transporting ATPase (EC 3.6.3.3) Cobalt-zinc-cadmium_resistance Cadmium-transporting ATPase (EC 3.6.3.3) Cation efflux system protein CusA Cation efflux system protein CusC precursor Cation efflux system protein CusF precursor Cd(II)/Pb(II)-responsive transcriptional regulator Cobalt-zinc-cadmium resistance protein Cobalt-zinc-cadmium resistance protein CzcA Cobalt-zinc-cadmium resistance protein CzcD Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family Copper sensory histidine kinase CusS Copper-sensing two-component system response regulator CusR DNA-binding heavy metal response regulator Heavy metal RND efflux outer membrane protein, CzcC family Heavy metal resistance transcriptional regulator HmrR Heavy metal sensor histidine kinase Hypothetical protein involved in heavy metal export Nickel-cobalt-cadmium resistance protein NccB Probable Co/Zn/Cd efflux system membrane fusion protein Probable cadmium-transporting ATPase (EC 3.6.3.3) Putative silver efflux pump Transcriptional regulator, MerR family Zinc transporter ZitB Zn(II) and Co(II) transmembrane diffusion facilitator Copper_homeostasis Blue copper oxidase CueO precursor CopG protein Copper chaperone Copper resistance protein B Copper resistance protein C precursor Copper resistance protein D Copper sensory histidine kinase CusS Copper tolerance protein Copper-binding periplasmic protein Copper-sensing two-component system response regulator CusR Copper-translocating P-type ATPase (EC 3.6.3.4) Cu(I)-responsive transcriptional regulator Cytochrome c heme lyase subunit CcmF Cytochrome c heme lyase subunit CcmH Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase Multicopper oxidase Multidrug resistance transporter, Bcr/CflA family Negative transcriptional regulator-copper transport operon Sensor protein copS (EC 2.7.3.-) Transcriptional activator protein CopR Fosfomycin_resistance Fosfomycin resistance protein FosA Fosfomycin resistance protein FosB Fosfomycin resistance protein FosX Lysozyme_inhibitors Inhibitor of vertebrate lysozyme precursor Membrane-bound lysozyme inhibitor of c-type lysozyme Per-activated serine protease autotransporter enterotoxin EspC Periplasmic lysozyme inhibitor of c-type lysozyme Mercuric_reductase Mercuric ion reductase (EC 1.16.1.1) PF00070 family, FAD-dependent NAD(P)-disulphide oxidoreductase Mercury_resistance_operon Mercuric ion reductase (EC 1.16.1.1) Mercuric resistance operon coregulator Mercuric resistance operon regulatory protein Mercuric transport protein, MerC Mercuric transport protein, MerE Mercuric transport protein, MerT Organomercurial lyase (EC 4.99.1.2) Periplasmic mercury(+2) binding protein Methicillin_resistance_in_Staphylococci Beta-lactamase regulatory sensor-transducer BlaR1 Beta-lactamase repressor BlaI D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13) D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13) D-alanyl transfer protein DltB FemA, factor essential for methicillin resistance FemB, factor involved in methicillin resistance FemC, factor involved in methicillin resistance FemD, factor involved in methicillin resistance FmhA protein of FemAB family FmhC protein of FemAB family FmtA protein involved in methicillin resistance FmtB (Mrp) protein involved in methicillin resistance and cell wall biosynthesis FmtC (MrpF) protein involved in methicillin resistance HTH domain protein SA1665, binds to mecA promoter region HmrA protein involved in methicillin resistance HmrB protein involved in methicillin resistance LytH protein involved in methicillin resistance Methicillin resistance regulatory sensor-transducer MecR1 Methicillin resistance regulatory sensor-transducer MecR1, truncated Methicillin resistance repressor MecI Penicillin binding protein PBP4 Penicillin-binding protein 1A/1B (PBP1) Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase Poly(glycerophosphate chain) D-alanine transfer protein DltD RNA polymerase sigma factor SigB Transposase for insertion sequence-like element IS431mec UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) tRNA-dependent lipid II--glycine ligase (FmhB) MexA-MexB-OprM_Multidrug_Efflux_System Multidrug efflux membrane fusion protein MexA Multidrug efflux transporter MexB Outer membrane protein OprM Transcriptional regulator MexR MexC-MexD-OprJ_Multidrug_Efflux_System Transcriptional regulator NfxB MexE-MexF-OprN_Multidrug_Efflux_System Multidrug efflux membrane fusion protein MexE Multidrug efflux transporter MexF Outer membrane protein OprN Transcriptional regulator MexT Multidrug_Resistance_Efflux_Pumps Acriflavin resistance protein Macrolide export ATP-binding/permease protein MacB (EC 3.6.3.-) Macrolide-specific efflux protein MacA Membrane fusion protein of RND family multidrug efflux pump Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps Multidrug efflux RND membrane fusion protein MexC Multidrug efflux RND transporter MexD Multidrug efflux pump component MtrF Multidrug resistance efflux pump PmrA Multidrug-efflux transporter, major facilitator superfamily (MFS) (TC 2.A.1) Probable outer membrane component of multidrug efflux pump Probable transcription regulator protein of MDR efflux pump cluster RND efflux system, inner membrane transporter CmeB RND efflux system, membrane fusion protein CmeA RND efflux system, outer membrane lipoprotein CmeC RND efflux system, outer membrane lipoprotein, NodT family Transcription regulator of multidrug efflux pump operon, TetR (AcrR) family Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family Transcriptional regulator NfxB Type I secretion outer membrane protein, TolC precursor Multidrug_Resistance_Operon_mdtRP_of_Bacillus MdtR transcriptional regulator, MarR family Multidrug efflux transporter MdtP Multidrug_efflux_pump_in_Campylobacter_jejuni_(CmeABC_operon) RND efflux system, inner membrane transporter CmeB RND efflux system, membrane fusion protein CmeA RND efflux system, outer membrane lipoprotein CmeC Transcriptional repressor of CmeABC operon, CmeR Multiple_Antibiotic_Resistance_MAR_locus Multiple antibiotic resistance protein MarA Multiple antibiotic resistance protein MarB Multiple antibiotic resistance protein MarC Multiple antibiotic resistance protein MarR Resistance_to_Vancomycin Protein VanZ Sensor histidine kinase VanS (EC 2.7.3.-) Vancomycin B-type resistance protein VanW Vancomycin B-type resistance protein VanX Vancomycin Teicoplanin A-type resistance protein VanA Vancomycin resistance protein VanH Vancomycin response regulator VanR Resistance_to_chromium_compounds Chromate resistance protein ChrB Chromate resistance protein ChrI Chromate transport protein ChrA Rhodanese-like protein ChrE Superoxide dismutase ChrC Superoxide dismutase SodM-like protein ChrF Resistance_to_fluoroquinolones DNA gyrase subunit A (EC 5.99.1.3) DNA gyrase subunit B (EC 5.99.1.3) Efflux pump Lde Topoisomerase IV subunit A (EC 5.99.1.-) Topoisomerase IV subunit B (EC 5.99.1.-) Streptococcus_pneumoniae_Vancomycin_Tolerance_Locus ABC transporter membrane-spanning permease, Pep export, Vex1 ABC transporter membrane-spanning permease, Pep export, Vex3 ABC transporter, ATP-binding protein Vex2 Sensor histidine kinase VncS Two-component response regulator VncR Streptothricin_resistance Streptothricin acetyltransferase, Streptomyces lavendulae type Teicoplanin-resistance_in_Staphylococcus Similar to Teicoplanin resistance associated membrane protein TcaA Teicoplanin resistance associated membrane protein TcaA Teicoplanin resistance associated membrane protein TcaB Teicoplanin-resistance associated HTH-type transcriptional regulator TcaR The_mdtABCD_multidrug_resistance_cluster Multidrug transporter MdtB Multidrug transporter MdtC Multidrug transporter MdtD Probable RND efflux membrane fusion protein Response regulator BaeR Sensory histidine kinase BaeS Zinc_resistance Response regulator of zinc sigma-54-dependent two-component system Sensor protein of zinc sigma-54-dependent two-component system Zinc resistance-associated protein 02 Toxins and superantigens Cholera_toxin Accessory cholera enterotoxin Enterotoxin, A subunit (NAD(+)--diphthamide ADP- ribosyltransferase) (EC 2.4.2.36) Enterotoxin, B subunit TCP pilus virulence regulatory protein ToxT, transcription activator Transcriptional activator ToxR Transmembrane regulatory protein ToxS Zona occludens toxin Cytolethal_distending_toxin_of_Campylobacter_jejuni Cytolethal distending toxin subunit A Cytolethal distending toxin subunit B Cytolethal distending toxin subunit C Cytolethal_distending_toxins Cytolethal distending toxin subunit A Cytolethal distending toxin subunit B Cytolethal distending toxin subunit C Putative outer membrane virulence protein PhoP Putative pertussis-like toxin subunit PtlA (EC 2.4.2.-) Putative pertussis-like toxin subunit PtlB Virulence protein MsgA Pertussis_toxin Major pilus subunit of type IV secretion complex (VirB2) Pertussis toxin subunit 1 precursor (NAD-dependent ADP-ribosyltransferase) (EC 2.4.2.-) Pertussis toxin subunit 2 precursor (PTX S2) Pertussis toxin subunit 3 precursor (PTX S3) Pertussis toxin subunit 4 precursor (PTX S4) Pertussis toxin subunit 5 precursor (PTX S5) Prophage-encoded_Exotoxins Mitogenic factor 2 Mitogenic factor 3 Mitogenic factor 4 Staphylococcal enterotoxin L Streptococcal pyrogenic exotoxin A (SpeA) Streptococcal pyrogenic exotoxin C (SpeC) Streptococcal pyrogenic exotoxin H (SpeH) Streptococcal pyrogenic exotoxin I (SpeI) Streptococcal pyrogenic exotoxin K (SpeK) Streptococcal pyrogenic exotoxin L (SpeL) Streptococcal pyrogenic exotoxin M (SpeM) Streptodornase D SLO-NADGH_Locus Nicotine adenine dinucleotide glycohydrolase (NADGH) (EC 3.2.2.5) Streptolysin O Unkown intruder Staphylococcus_Two-component_and_Pore-forming_Cytolysins Alpha-hemolysin precursor Gamma-hemolysin component A Gamma-hemolysin component B Gamma-hemolysin component C IgG-binding protein SBI Leukotoxin LukD Leukotoxin LukE Panton-Valentine leukocidin chain F precursor Panton-Valentine leukocidin chain S precursor Streptolysin_S_Biosynthesis_and_Transport Asparagine-rich ORFan next to Sag operon Export ABC transporter ATP-binding protein Export ABC transporter permease Streptolysin S biosynthesis protein (SagF) Streptolysin S biosynthesis protein B (SagB) Streptolysin S biosynthesis protein C (SagC) Streptolysin S biosynthesis protein D (SagD) Streptolysin S export transmembrane permease (SagH) Streptolysin S export transmembrane permease (SagI) Streptolysin S precursor (SagA) Streptolysin S self-immunity protein (SagE) 02 Bacterial_cyanide_production_and_tolerance_mechanisms Carbonic anhydrase (EC 4.2.1.1) Cyanide hydratase (EC 4.2.1.66) Cyanide insensitive terminal oxidase, putative subunit III Cyanide insensitive terminal oxidase, subunit I Cyanide insensitive terminal oxidase, subunit II Formate dehydrogenase O alpha subunit (EC 1.2.1.2) Formate dehydrogenase O beta subunit (EC 1.2.1.2) Formate dehydrogenase O gamma subunit (EC 1.2.1.2) Hydrogen cyanide synthase HcnA Hydrogen cyanide synthase HcnB Hydrogen cyanide synthase HcnC NADH peroxidase Npx (EC 1.11.1.1) Sulfate transporter family protein in cluster with carbonic anhydrase Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) formate dehydrogenase formation protein FdhE C_jejuni_colonization_of_chick_caeca 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(Lipid carrier) aminotransferase Alpha-1,4-N-acetylgalactosamine transferase PglH (EC 2.4.1.-) Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY Cj0454c Cj0456c Cj0618 Cytochrome C551 peroxidase (EC 1.11.1.5) Flagellar biosynthesis protein FliR Flagellar hook-associated protein FlgK Flagellar motor rotation protein MotA Flagellar motor rotation protein MotB MCP-domain signal transduction protein Paralysed flagella protein PflA Phosphate acetyltransferase (EC 2.3.1.8) Predicted signal transduction protein Putative amino-acid transport protein RNA polymerase sigma factor for flagellar operon RNA polymerase sigma-54 factor RpoN Rrf2 family transcriptional regulator UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) acyl-acyl carrier protein synthetase (EC 6.2.1.20) Streptococcus_pyogenes_Virulome Antiphagocytic M protein C3 family ADP-ribosyltransferase (EC 2.4.2.-) C5a peptidase (EC 3.4.21.-) CAMP factor Collagen-like surface protein D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13) D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13) Fibrinogen-binding protein Fibronectin-binding protein Hyaluronan synthase (EC 2.4.1.212) Hyaluronate lyase precursor (EC 4.2.2.1) Immunoglobulin G-endopeptidase (IdeS) Mitogenic factor 2 Mitogenic factor 3 Mitogenic factor 4 Nicotine adenine dinucleotide glycohydrolase (NADGH) (EC 3.2.2.5) Plasmin(ogen) receptor Protein G-related alpha 2 macroglobulin-binding protein (GRAB) Secreted Endo-beta-N-acetylglucosaminidase (EndoS) Serine endopeptidase ScpC (EC 3.4.21.-) Serum opacity factor Streptococcal inhibitor of complement (SIC) Streptococcal mitogenic exotoxin Z (SmeZ) Streptococcal pyrogenic exotoxin A (SpeA) Streptococcal pyrogenic exotoxin B (SpeB) Streptococcal pyrogenic exotoxin C (SpeC) Streptococcal pyrogenic exotoxin G (SpeG) Streptococcal pyrogenic exotoxin G (SpeG) fragment Streptococcal pyrogenic exotoxin H (SpeH) Streptococcal pyrogenic exotoxin I (SpeI) Streptococcal pyrogenic exotoxin J (SpeJ) Streptococcal pyrogenic exotoxin J (SpeJ) fragment Streptococcal pyrogenic exotoxin K (SpeK) Streptococcal pyrogenic exotoxin L (SpeL) Streptococcal pyrogenic exotoxin M (SpeM) Streptococcal superantigen A (SSA) Streptodornase B Streptodornase D Streptokinase Streptolysin O Streptolysin S precursor (SagA)
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