Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients with Cardiovascular Disease (FOCUS)

Objectives

This was a multi-center randomized trial in 2016 hip fracture patients undergoing surgical repair that compared two transfusion strategies: 1) Maintain postoperative hemoglobin concentration above 10 g/dL and 2) Symptomatic strategy in which blood transfusion is withheld until the patient develops symptoms of anemia or hemoglobin concentration less than 8 g/dL. Outcomes included functional recovery, 30 and 60-day survival, myocardial infarction, nursing home placement, and postoperative complications.

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