Stroke Research & Clinical Trials

Clinical Trials

The NINDS conducts stroke research and clinical trials at its laboratories and clinics at the NIH, and through grants to major medical institutions across the country.

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Clinical Trials
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RESEARCH PROGRAMS: CREST Study Sites

ALABAMA

University of Alabama at Birmingham
Birmingham, AL
PI: William D. Jordan, Jr., MD

ARKANSAS

Central Arkansas Veteran Healthcare System
Little Rock, AR
PI: John F. Eidt, MD

ARIZONA

Barrow Neurological Institute
Phoenix, AZ
PI: Robert Spetzler, MD

Mayo Clinic Scottsdale
Scottsdale, AZ
PI: Bart M. Demaerschalk, MD, MSc, FRCP (C)

University of Arizona 
Tucson, AZ
PI: Joseph Mills, MD

CALIFORNIA

Kaiser Permanente Medical Center
San Diego, CA
PI: Robert James Hye, MD, FACS

San Francisco VA Medical Center
San Francisco, CA
PI: Joseph Rapp, MD

St. Joseph's Medical Center
Stockton, CA
PI: Andrew Macbeth, MD
      Venkata Emani, MD

UCLA
Los Angeles, CA
PI: Wesley S. Moore, MD

USC University Hospital & LA County Hospital
Los Angeles, CA
PI: Fred A. Weaver, MD

DELAWARE

Christiana Health Care System
Newark, DE
PI: John W. Shuck, MD
      William Schickler, MD, FACS

FLORIDA

Florida Hospital
Orlando, FL
PI: Frank R. Hellinger, II, MD

Leesburg Medical Center
Leesburg, FL
PI: David C. Lew, MD, FACC, FSCAI

Mayo Clinic Jacksonville
Jacksonville, FL
PI: Albert G. Hakaim, MD, MSc, FACS

Miami Cardiac & Vascular Institute
Miami, FL
PI: Barry T. Katzen, MD, FACR, FACC, FSIR

Morton Plant Hospital
Clearwater, FL
PI: Eric M. Lopez del Valle, MD
      Ajay Arora, MD

Orlando Regional Healthcare
Orlando, FL
PI: Joseph G. Andriole, MD

USF/Tampa General Hospital
Tampa, FL
PI:  Dennis F. Bandyk, MD

GEORGIA

Atlanta Veteran’s Affairs Medical Center
Atlanta, GA
PI: Elliot Chaikof, MD, PhD

Emory University
Atlanta, GA
PI: Elliot Chaikof, MD

Piedmont Hospital/Fuqua Heart Center
Atlanta, GA
PI: Bhagat K. Reddy, MD, FACC

St. Joseph's/Candler Health System
Savannah, GA
PI: Jay U. Howington, MD, FACS

St. Joseph's Hospital of Atlanta
Lawrenceville, GA
PI: Louis Heller, MD

ILLINOIS

Alexian Brothers Medical Center
Elkgrove, IL
PI: Sarah A. Johnson, MD

Central Dupage Hospital
Winfield, IL
PI: Harish N. Shownkeen, MD

Loyola University Medical Center
Maywood, IL
PI: Jose Biller, MD, FACP, FAAN, FAHA

Northwestern Memorial Hospital
Chicago, IL
PI: Mark K. Eskandari, MD

Peoria Radiolgy
Peoria, IL
PI: Kenneth William Fraser, MD

Prairie Cardiology/St. John’s Hospital
Springfield, IL
PI: Gregory Mishkel, MD, FRCPC, FACC

Rush University Medical Center
Chicago, IL
PI: Robert  Jeffrey Snell, MD

Southern Illinois School of Medicine
Springfield, IL
PI: Kim J. Hodgson, MD

INDIANA

Lutheran Hospital of Indiana
Fort Wayne, IN
PI: Steven W. Orlow, MD

Parkview Hospital
Fort Wayne, IN    
PI: Hollace D. Chastain, II, MD, FACC, FSCAI

St. Vincent Hospital
Indianapolis, IN
PI: Kannan Natarajan, MD

IOWA

Iowa Heart Center
West Des Moines, IA
PI: Liberato A. Iannone, MD, FACC, FACCP

KENTUCKY

Central Baptist Hospital
Lexington, KY
PI: William Brooks, MD

University of Louisville
Louisville, KY
PI: Alex Abou-Chebl, MD

LOUISIANA

Baton Rouge General/Vascular Surgery Associates
Baton Rouge, LA
PI: Albert Sam, II, MD, MS, MMM

Ochsner Clinic
New Orleans, LA
  PI: W. Charles Ster nberg III, MD, FACS

MARYLAND

Ann Arundel Medical Center
Annapolis, MD
PI: John D. Martin, MD, FACS

Johns Hopkins Hospital
Baltimore, MD
PI: Mahmoud Malas, MD, FACS

Washington Adventist Hospital
Takoma Park, MD
PI: Fayaz Shawl, MD, FACP, FCCP, FACC

MASSACHUSETTS

Beth Israel Deaconess
Boston, MA
PI: Marc Schermerhorn, MD

Brigham & Women's Hospital
Boston, MA
PI: Michael Belkin, MD

Cape Cod Hospital
Hyannis, MA
PI: Richard B. Zelman, MD

Mass General Hospital
Boston, MA
PI: Kenneth Rosenfield, MD

St. Elizabeth's Hospital
Boston, MA
PI: Peter A. Soukas, MD

MICHIGAN

Henry Ford Hospital
Detroit, MI
PI: Alexander Shepard, MD

Michigan Heart & Vascular
Ypsilanti, MI
PI: Herbert D. Aronow, MD, MPH

Michigan Vascular Research Center
Flint, MI
PI: Robert Molnar, MD

Providence St. John Hospital
Southfield, MI
PI: Jamal Zarghami, MD

Spectrum Health
Grand Rapids, MI
PI: Ashraf Mansour, MD

St. John Hospital and Medical Center
Detroit, MI
PI: Thomas P. Davis, MD

William Beaumont Hospital
Brigham Farms, MI
PI: O. William Brown, MD
      

MINNESOTA

Mayo Clinic Rochester
Rochester, MN
PI: Harry J. Cloft, MD

North Memorial Health Care
Golden Valley, MN
PI: Irfan Mohammad Altafullah, MD

MISSISSIPPI

Mississippi Baptist Medical Center
Jackson, MS
PI: Charles Snow O’Mara, MD

MISSOURI

St. John's Mercy Medical Center
St. Louis, MO
PI: Vito A. Mantese, MD

St. Joseph's Medical Center,  KC
Kansas City, MO
PI: David J. Burkart, MD

St. Luke's Hospital
Kansas City, MO
PI: Steven Laster, MD

MONTANA

St. Patrick's Hospital
Missoula, MT
PI: Mark Louis Sanz, MD

NEW HAMPSHIRE

Dartmouth Hitchcock Medical Center
Lebanon, NH
PI: Richard J. Powell, MD

NEW JERSEY

St. Michael's Medical Center
Newark, NJ
PI: Zafar Jamil, MD

NEW YORK

Columbia Presbyterian
New York, NY
PI: William A. Gray, MD

Cornell Medical Center
New York, NY
PI: Pierre Gobin, MD

Lenox Hill Hospital
New York, NY
PI: Gary S. Roubin, MD, PhD

Millard Fillmore Neurosurgery/SUNY Buffalo
Buffalo, NY
PI: Leo Nelson Hopkins, MD

St. Francis Hospital
Roslyn, NY
PI: George A. Petrossian, MD

University of Rochester/Strong Memorial Hospital
Rochester, NY
PI: Craig Richard Narins, MD

Vascular Interventional Project,  Inc.
Albany, NY
PI: Manish Mehta, MD, MPH

Westchester Medical Center
Valhalla, NY
PI: Anthony Pucillo, MD

NORTH CAROLINA

Carolinas Medical Center/Sanger Clinic
Charlotte, NC
PI: Michael Rinaldi, MD

Duke University Medical Center
Durham, NC
PI: Richard McCann, MD

Forsyth Medical Center
Winston-Salem, NC
PI: Donald V. Heck, MD

Wake Forest University
Winston-Salem, NC
PI: Kimberley J. Hansen, MD

OHIO

Cleveland Clinic
Cleveland, OH
PI: Daniel Clair, MD

Mayfield Clinic/University of Cincinnati
Cincinnati, OH
PI: Andrew J. Ringer, MD

Midwest Cardiology/Grant Riverside Methodist Hospital
Columbus, OH
PI: Gary M. Ansel, MD

The Christ Hospital
Cincinnati, OH
PI: Robert V. Bulas, MD

Toledo Hospital
Toledo, OH
PI: Anthony J. Comerota, MD

University of Toledo,  Health Science Campus
Toledo, OH
PI: Munier Nazzal, MD, FACS

OKLAHOMA

Oklahoma Foundation for Cardiovascular Research
Oklahoma City, OK
PI: Jim G. Melton, D.O.

OREGON

Oregon Health Science University
Portland, OR
PI: Wayne Marston Clark, MD

Rogue Valley Medical Center
Medford, OR
PI: Kent Dauterman, MD

PENNSYLVANIA

Allegheny General Hospital
Pittsburgh, PA
PI: Daniel Benckart, MD

Geisinger Medical Center
Danville, PA
PI: James R. Elmore, MD, FACS

Lehigh Valley Hospital
Allentown, PA
PI: Bryan Kluck, MD
      Eric P. Wilson, MD

Thomas Jefferson University Hospital
Philadelphia, PA
PI: Robert Rosenwasser, MD

Tri-State Medical Center
Beaver, PA
PI: Richard Begg, MD, FACC

UPMC-Presbyterian University Hospital
Pittsburgh, PA
PI: Lawrence Wechsler, MD

UPMC/Shadyside Hospital
Pittsburgh, PA
PI: Lawrence Wechsler, MD

University of Pennsylvania
Philadelphia, PA
PI: Michael Golden, MD

TENNESSEE

Baptist Hospital West,  Inc.
Knoxville, TN
PI: Malcolm T. Foster, III, MD

Baptist Memorial Hospital of Tennessee
Memphis, TN
PI: Adam Stephen Arthur, MD, MPH

TEXAS

Methodist Hospital
Houston, TX
PI: David Chiu, MD, FAHA

Scott & White Memorial Hospital
Temple, TX
PI: Walter S. Lesley, MD

UT Houston/Memorial Hermann
Houston, TX
PI: Nicole Gonzales, MD

University of Texas - Southwestern
Dallas, TX
PI: Carlos H. Timaran, MD

UTAH

LDS Hospital
Murray, UT
PI: James Lee Burke, MD, FACC

VIRGINIA

University of Virginia
Charlottesville, VA
PI: Avery J. Evans, MD

WASHINGTON

Deaconess Medical Center
Spokane, WA
PI: Pierre Paul Leimgruber, MD

Providence Medical Research Center
Spokane, WA
PI: Rodney D. Raabe, MD

Swedish Heart Institute
Seattle, WA
PI: Mark Reisman, MD, FACC, FSCAI

WEST VIRGINIA

Charleston Area Medical Center
Charleston, WV
PI: Mark C. Bates, MD, FACC, FSCAI

WISCONSIN

Marshfield Clinic
Marshfield, WI
PI: Percy N. Karanjia, MD

St. Luke's Medical Center
Milwaukee, WI
PI: Tanvir Bajwa, MD

CANADA

Alberta

Foothills Hospital University of Calgary
Calgary, Alberta
PI: Michael D. Hill, MD, MSc FRCPC

British Columbia

Vancouver General Hospital
Vancouver, British Columbia
PI: Philip Teal, MD

Manitoba

University of Manitoba
Winnipeg, Manitoba
PI: Randy P. Guzman, MD, FRCSC, FACS, RVT

Ontario

London Health Science Centre
London, Ontario
PI: David M. Pelz, MD, FRCPC

Ottawa Hospital
Ottawa, Ontario
PI: Grant Stotts, MD, FRCPC

St. Michael's Hospital
Toronto, Ontario
PI: Walter Montanera, MD, FRCP (C)

Toronto Western Hospital
Toronto, Ontario
PI:  Richard I. Farb, MD

Trillium Health Centre
Mississaugu, Ontario
PI: Daniel Selchen, MD, FRCP (C)

Quebec

CHA Hôpitál L'énfant Jésus Hospital
Quebec City, Quebec
PI: Ariane Mackey, MD, FRCP