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Histoplasmosis is a disease caused when airborne spores of the fungus Histoplasma capsulatum are inhaled in the lungs. Histoplasmosis is sometimes so mild that it produces no apparent symptoms. However, later it can lead to a serious eye disease called ocular histoplasmosis syndrome (OHS), a leading cause of vision loss in Americans ages 20 to 40.

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Department of Health and Human Services NIH, the National Institutes of Health