The American Society for Cell Biology Annual Meeting
San Diego, CA
Special Interest Subgroup on December 5, 2009
Session Title: Cancer Cell Evolution: Is it Survival of the Fittest?
Organizers:
Anna Maria Calcagno, Project Manager, Physical Science-Oncology Centers Program, National Cancer Institute, NIH
Jerry S. H. Lee, Special Assistant to the NCI Deputy Director, National Cancer Institute, NIH
The evolutionary theory constitutes the nexus of modern biology and is implemented in all its disciplines. The application of evolutionary theory to cells has spurred the development of mechanistic, quantitative models and innovative techniques used in molecular genetics. The National Cancer Institute’s Physical Sciences in Oncology Program, a new initiative linking the physical sciences with cancer biology, focuses on evolution and evolutionary theory in cancer as one of its four themes. This recent integration of cancer biology and evolutionary biology may provide unique insights into understanding cancer initiation and progression. This session will highlight the use of evolutionary theories in cancer cell biology and will illustrate various tools utilized in such studies to uncover the evolution of cells.
Moderator: Sean E. Hanlon, National Cancer Institute, NIH
Speakers:
12:30 p.m. - 12:40 p.m.
An Evolutionary Side to Cancer - Physical Sciences in Oncology Perspective
Larry Nagahara, Program Director, Physical Science-Oncology Centers Program, National Cancer Institute, NIH
12:40 p.m. - 1:20 p.m.
The Theory of Cancer
Carlo C. Maley, Assistant Professor, Molecular and Cellular Oncogenesis Program, Wistar Institute
1:20 p.m. - 2:00 p.m.
Evolution and the Initiation and Progression of Cancer
Thea D. Tlsty, Professor of Pathology, University of California, San Francisco
2:00 p.m. - 2:20 p.m.
Break
2:20 p.m. - 3:00 p.m.
Evolution of Drug Resistance in Cancer Cells
Michael M. Gottesman, Chief, Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH
3:00 p.m. - 3:40 p.m.
Evolutionary Dynamics of Cancer
Franziska Michor, Assistant Member, Computational Biology Program, Memorial Sloan-Kettering Cancer Center
3:40 p.m. - 4:20 p.m.
Reconstructing Cancer Cell Evolution from Somatic Genome Variations
Darryl Shibata, Professor of Pathology, University of Southern California
4:20 p.m. - 5:00 p.m.
General Questions and Answers
