TOOLS, PRODUCTS, AND RESOURCES

Guidelines to Help Researchers Evaluate Whether Markers or Assays Are Ready for Use in Clinical Settings: Reporting Studies of Tumor Markers

http://cdp.cancer.gov/scientificPrograms/pacct/remark.htm

The REporting recommendations for tumor MARKer prognostic studies (REMARK) guidelines resulted from a collaboration between a PACCT strategy group and an NCI-EORTC working group. REMARK includes information that should be reported in all publications about tumor markers. These recommendations were published simultaneously in the British Journal of Cancer, European Journal of Cancer, Journal of Clinical Oncology, Journal of the National Cancer Institute, and Nature Clinical Practice Oncology.

The recommendations are available on the CDP website to help the research community and members of journal editorial boards ensure that more complete information is included in publications about prognostic markers. The recommendations are organized according to a format typical of articles appearing in biomedical journals, corresponding to the introduction, materials and methods, results, and discussion sections.

McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM. Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 2005:93;387-91.
http://www.ncbi.nlm.nih.gov/pubmed/16106245

McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM. Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. REporting recommendations for tumour MARKer prognostic studies (REMARK). Eur J Cancer 2005:41;1690-6.
http://www.ncbi.nlm.nih.gov/pubmed/16043346

McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM; Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumor marker prognostic studies. J Clin Oncol 2005:23;9067-72.
http://www.ncbi.nlm.nih.gov/pubmed/16172462

McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM; Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumor marker prognostic studies (REMARK). J Natl Cancer Inst 2005:97;1180-4.
http://www.ncbi.nlm.nih.gov/pubmed/16106022

McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM; Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. REporting recommendations for tumor MARKer prognostic studies (REMARK). Nat Clin Pract Oncol 2005:2;416-22.
http://www.ncbi.nlm.nih.gov/pubmed/16130938