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Grant Details

Grant Number: 5R01CA084063-12 Interpret this number
Primary Investigator: Brook, Judith
Organization: New York University School Of Medicine
Project Title: Tobacco Use Among Minority Youth: a Longitudinal Study
Fiscal Year: 2011
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Abstract

DESCRIPTION (provided by applicant): This is a competing continuation application. The overall goals of this longitudinal study are to examine the etiologic determinants and consequences of African-American and Puerto Rican adult tobacco use and dependence. The sample (N=500) was interviewed at four points in time: early adolescence, middle adolescence, late adolescence, and young adulthood. A fifth wave of data collection is proposed for the participants, who will be an average age of 32, and their partners, to accomplish the following: (1) examine interrelations and interactions of personality (including psychopathology), family, peer, ecological, and cultural factors as they affect the course of tobacco use and dependence over time (stability and change); (2) study the consequences of long-term tobacco use and dependence on adult psychopathology and functioning; and (3) examine the impact of parental tobacco use and dependence on precursors of offspring tobacco use, including offspring externalizing, internalizing, and parents' expectations of offspring's future smoking. As in the past, separate interviews with adults will be conducted in private by trained interviewers. Scales with adequate psychometric properties measuring the independent variables will be developed from the interview schedules. The primary analytic techniques will be causal analysis, logistic regression analysis, and growth mixture modeling. The significance of this study lies in its in-depth intrapersonal and interpersonal data available at several stages of development. We can examine the pathways to tobacco use and dependence from early adolescence through adulthood as well as the course of tobacco use and dependence overtime, i.e., the factors related to the respondent's becoming more or less involved in tobacco use and dependence over a span of 17 years. We can also examine the factors related to cessation of use. Such knowledge will help pinpoint those adolescents and young adults at risk for later tobacco use and dependence and will provide detailed and specific guidelines for prevention and treatment. Our longitudinal study of the consequences of tobacco use and dependence in African-Americans and Puerto Ricans is unique in that the long-term psychosocial effects of tobacco use and dependence can be evaluated to see if their impact is cumulative. Identification of adolescent and young adult factors that can exacerbate the adverse impact of the consequences of tobacco use and dependence on later adult psychosocial functioning will provide additional information necessary for effective prevention and treatment efforts. Findings will help physicians, educators, and policy makers provide healthy environments.

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Publications

Predictors of DSM and Fagerstrom-defined nicotine dependence in African American and Puerto Rican young adults.
Authors: Brook JS, Koppel J, Pahl K
Source: Subst Use Misuse, 2009;44(6), p. 809-22.
PMID: 19444723
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Grant Numbers:
NCI NIH HHS - R01 CA084063-09 NIDA NIH HHS - K05 DA000244-15 NIDA NIH HHS - DA00244
NCI NIH HHS - CA84063 NIDA NIH HHS - R01 DA005702-18 NIDA NIH HHS - DA05702

MeSH Terms:
Young Adult New York City Hispanic Americans
Tobacco Use Disorder Humans Adult
African Americans Adolescent Male
Female Diagnostic and Statistical Manual of Mental Disorders

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Psychosocial predictors of nicotine dependence in Black and Puerto Rican adults: a longitudinal study.
Authors: Brook JS, Brook DW, Zhang C
Source: Nicotine Tob Res, 2008 Jun;10(6), p. 959-67.
PMID: 18584459
Related Citations

Grant Numbers:
NIDA NIH HHS - 2K05 DA00244 NCI NIH HHS - 7R01 CA84063 NIDA NIH HHS - 7R01 DA05702

MeSH Terms:
Tobacco Use Disorder Humans Personality
African Americans Longitudinal Studies Comorbidity
Risk Assessment Socioeconomic Factors Smoking
New York City Prospective Studies Hispanic Americans
Logistic Models Risk Factors Adult
Health Behavior Adolescent Urban Population
Female

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Pathways to nicotine dependence in African American and Puerto Rican young adults.
Authors: Brook JS, Duan T, Brook DW, Ning Y
Source: Am J Addict, 2007 Nov-Dec;16(6), p. 450-6.
PMID: 18058409
Related Citations

Grant Numbers:
NIDA NIH HHS - DA00244 NCI NIH HHS - CA84063 NIDA NIH HHS - DA05702

MeSH Terms:
Models, Psychological Age Factors Conflict (Psychology)
Educational Status Questionnaires Tobacco Use Disorder
Humans Personality African Americans
Age Distribution Smoking Marital Status
Identification (Psychology) Family Relations Hispanic Americans
Social Class Risk Factors Adult
Substance-Related Disorders Parents Female
Male

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Trajectories of cigarette smoking among African Americans and Puerto Ricans from adolescence to young adulthood: associations with dependence on alcohol and illegal drugs.
Authors: Brook JS, Balka EB, Ning Y, Brook DW
Source: Am J Addict, 2007 May-Jun;16(3), p. 195-201.
PMID: 17612823
Related Citations

Grant Numbers:
NIDA NIH HHS - DA0244 NCI NIH HHS - CA84063 NIDA NIH HHS - DA05702

MeSH Terms:
Adolescent Behavior Age of Onset Humans
African Americans New York City Smoking
Hispanic Americans Risk Factors Adult
Alcoholism Street Drugs Substance-Related Disorders
Adolescent Urban Population Time Factors

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Maternal cigarette smoking during pregnancy and child aggressive behavior.
Authors: Brook DW, Zhang C, Rosenberg G, Brook JS
Source: Am J Addict, 2006 Nov-Dec;15(6), p. 450-6.
PMID: 17182447
Related Citations

Grant Numbers:
NIDA NIH HHS - 2K05 DA00244 NCI NIH HHS - 7R01 CA84063 NIDA NIH HHS - 7R01 DA05702

MeSH Terms:
Maternal Behavior Child Behavior Disorders Humans
Child Pregnancy Socioeconomic Factors
Smoking New York City Hispanic Americans
Parenting Risk Factors Antisocial Personality Disorder
Aggression Personality Assessment Urban Population
African Continental Ancestry Group Female Male
Prenatal Exposure Delayed Effects

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Personality risk factors associated with trajectories of tobacco use.
Authors: Brook JS, Ning Y, Brook DW
Source: Am J Addict, 2006 Nov-Dec;15(6), p. 426-33.
PMID: 17182444
Related Citations

Grant Numbers:
NCI NIH HHS - 7R01 CA84063-05 NIDA NIH HHS - 7R01 DA05702-16 NIDA NIH HHS - 2K05 DA00244-12

MeSH Terms:
Humans Alcohol Drinking Longitudinal Studies
Marijuana Abuse Character Comorbidity
Socioeconomic Factors Smoking New York City
Internal-External Control Interview, Psychological Prospective Studies
Hispanic Americans Risk Factors Adult
Substance-Related Disorders Personality Assessment Adolescent
Urban Population African Continental Ancestry Group Female
Male

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Peer and parental influences on longitudinal trajectories of smoking among African Americans and Puerto Ricans.
Authors: Brook JS, Pahl K, Ning Y
Source: Nicotine Tob Res, 2006 Oct;8(5), p. 639-51.
PMID: 17008191
Related Citations

Grant Numbers:
NIDA NIH HHS - DA05072 NIDA NIH HHS - DA00244 NCI NIH HHS - CA84063

MeSH Terms:
Questionnaires Adolescent Behavior Risk-Taking
Humans African Americans Parent-Child Relations
Peer Group Smoking New York City
Hispanic Americans Puerto Rico Smoking Cessation
Adult Adolescent Community Health Services
Female Male

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