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Question ID: WS-39
Submitted by: Patrick Brown
February 4, 2011
Comments
Question ID: WS-39
Submitted by: Patrick Brown
February 4, 2011
Local intrachromosomal rearrangements escape detection by essentially all standard methods for characterizing cancer genomes, yet there is growing evidence that they may be among the most common and perhaps important genetic lesions in cancer. What is the molecular pathogenesis of these rearrangements? How can we efficiently and systematically identify them? How important are they in cancer pathogenesis and what roles do they play?
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Comments
2011/04/06 18:02:13.070 GMT-4
Submitted By Rao Divi
Submitted By Rao Divi
Large scale somatic genetic variations, changes in repeat elements, retrotransposon activation in tissues may contribute to cancer. Therefore, this is a very interesting topic to pursue.
