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Question ID: WS-50
Submitted by: Deadly Cancer Coalition
February 8, 2011

Question: Can we gain greater understanding of the mechanisms of tumor metastasis? Background: Even cancer types that are typically responsive to current treatment modalities tend to be extremely difficult to treat once the cancer starts to metastasize. A commonality of some of the deadliest cancers is a proclivity to metastasize to critical organs, tragically combined with a frequency of late diagnoses. Feasibility: A better understanding of the metastasis-related genes and pathways would benefit all solid tumor types.

Average Score: 3.5 3.5 star (1 evaluation)
Provocativeness - 4.0
Novelty - 2.0
Public Health Significance - 5.0
Feasibility - 2.0

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