Deng, W., Lee, J.J, Wang, H., Reik, A., Gregory, P.D., Dean, A. and Blobel, G. Manipulating long-range chromosomal interactions at an endogenous locus by tethering of a “looping” factor. Cell, in press, 2012.
Bender, M.A., Ragoczy, T., Lee, J., Byron, R., Telling, A., Dean, A. and Groudine, M. The hypersensitive sites of the murine β-globin locus control region act independently to effect nuclear localization and transcriptional elongation. Blood, in press, 2012. [Full Text/Abstract]
Krivega, I. and Dean, A. Enhancer and promoter interactions―long distance calls. Current Opinion in Genetics and Development, in press, 2012. [Full Text/Abstract]
Krivega, M. and Dean, A (2011) Insulators organize chromatin: emerging rules of the game. Molecular Cell, 44:1-2. [Full Text/Abstract]
Lienert, F., Wirbelauer, C., Som, I., Dean, A. Mohn, F. and Schubeler, D (2011) Identification of genetic elements that autonomously determine DNA methylation states. Nature Genetics, 43:1091-7. [Full Text/Abstract]
Kiefer, C.M., Lee, J.J., Hou, C, Lee, Y.T., Meier, E.R., Miller, J.L. and Dean, A (2011) Distinct Lbd1/NLI complexes orchestrate γ-globin repression and re-activation through ETO2 in human adult erythroid cells. Blood, 118:6200-6208. [Full Text/Abstract]
Dean, A (2011) In the loop: long range chromatin interactions and gene regulation. Briefings in Functional Genomics, 10:3-10. [Full Text/Abstract]
Li, L., Lee, J.Y., Gross, J., Song, S.-H., Dean, A. and Love, P (2010) An essential role for Lim domain binding protein 1 in primitive and definitive erythropoiesis. Journal of Experimental Medicine, 207:2543-2550. [Full Text/Abstract]
Song, S.-H., Kim, A., Ragoczy, T., Bender, M. A., Groudine, M. and Dean, A (2010) Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation. Blood, 116: 2356-2364. [Full Text/Abstract]
Hou C, Dale R, Dean, A (2010) Cell-type specificity of chromatin organization mediated by CTCF and cohesin. Proc Natl Acad Sci U S A 107:3651-56. [Full Text/Abstract]
Sripichai O, Kiefer CM, Bhanu NV, Tanno T, Noh SJ, Goh SH, Russell JE, Rognerud CL, Ou CN, Oneal PA, Meier ER, Gantt NM, Byrnes C, Lee YT, Dean A, Miller JL (2009) Cytokine mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming. Blood, 114:2299-2306. [Full Text/Abstract]
Bhatia H, Hallock JL, Dutta A, Karkashon S, Sterner LS, Miyazaki T, Dean A, Little JA (2009) Short-chain fatty acid-mediated effects on erythropoiesis in primary definitive erythroid cells. Blood 113:6440-8. [PubMed] [Full Text via PubMed Central]
Kim SI, Bultman SJ, Kiefer CM, Dean A, Bresnick EH (2009) BRG1 requirement for long-range interaction of a locus control region with a downstream promoter. Proc Natl Acad Sci U S A 106:2259-64. [PubMed] [Full Text via PubMed Central]
Dean A, Fiering S (2009) Epigenetic Gene Regulation-Lessons from Globin, in Epigenomics. Springer (New York, NY, USA), pp. 283-299.
Kiefer CM, Hou C, Little JA, Dean A (2008) Epigenetics of beta-globin gene regulation. Mutat Res 647:68-76. [PubMed] [Full Text via PubMed Central]
Hou C, Zhao H, Tanimoto K, Dean A (2008) CTCF-dependent enhancer-blocking by alternative chromatin loop formation. Proc Natl Acad Sci U S A 105:20398-403. [PubMed] [Full Text via PubMed Central]
Song, SH, Hou, C, Dean, A (2007) A positive role for NLI/Ldb1 in long range beta-globin locus control region function Molecular Cell 28: 810-822.
Kim A, Zhao H, Ifrim I, Dean A (2007) Beta-globin intergenic transcription and histone acetylation dependent on an enhancer. Mol Cell Biol 27: 2980-6. [Full Text/Abstract]
3. Kim A, Kiefer CM, Dean A (2007) Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences. Mol Cell Biol 27: 1271-1279. [Full Text/Abstract]
Kim A, Song SH, Brand M, Dean A (2007) Nucleosome and transcription activator antagonism at human {beta}-globin locus control region DNase I hypersensitive sites. Nucleic Acids Res, 35: 5831-5838. [Full Text/Abstract]
Zhao H, Kim A, Song SH, Dean A (2006) Enhancer blocking by chicken beta-globin 5''-HS4: role of enhancer strength and insulator nucleosome depletion. J Biol Chem 281: 30573-80. [Full Text/Abstract]
Dean A (2006) On a chromosome far, far away: LCRs and gene expression. Trends Genet 22: 38-45. [Full Text/Abstract]
Zhao H, Dean A (2005) Organizing the genome: enhancers and insulators. Biochem Cell Biol 83: 516-24. [Full Text/Abstract]
Zhao H, Dean A (2004) An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene. Nucleic Acids Res 32: 4903-19. [Full Text/Abstract]
Dean A (2004) Chromatin remodelling and the interaction between enhancers and promoters in the beta-globin locus. Brief Funct Genomic Proteomic 2: 344-54. [Full Text/Abstract]
Kim A, Dean A (2004) Developmental stage differences in chromatin subdomains of the beta-globin locus. Proc Natl Acad Sci U S A 101: 7028-33. [Full Text/Abstract]
Kim A Dean A (2003) A human globin enhancer causes both discrete and widespread alterations in chromatin structure. Mol Cell Biol 23: 8099-109. [Full Text/Abstract]
Gui CY Dean A (2003) A major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter. Proc Natl Acad Sci U S A 100: 7009-14. [Full Text/Abstract]
Jackson DA McDowell JC Dean A (2003) Beta-globin locus control region HS2 and HS3 interact structurally and functionally. Nucleic Acids Res 31: 1180-90. [Full Text/Abstract]
