2-AMINO-1,3,4-THIADIAZOLE

NSC - 4728

SMILES: Nc1nncs1

Chemical Name: 1,3,4-Thiadiazol-2-amine,2-Amino-1,3,4-Thiadiazole

Other Name: ATDA

CAS Registry Number: 4005-51-0

Molecular Formula: C2H3N3S      M.W.: 101.1

How Supplied: Sterile, 200 mg, vial: supplied as a lyophilized
powder in 30 mL flint vials.

Solution Preparation: 200 mg/vial: When constituted with
19.9 mL of Sterile Water for Injection, USP, 0.9% Sodium
Chloride Injection, USP, or 5% Dextrose Injection, USP, each
milliliter contains 10 mg of 2-amino-1,3,4-thiadiazole. The pH
of the constituted solution is 5.5 to 7.0.

Storage: Store the intact vials at room temperature.

Stability: The intact vials are stable for 5 years at room
temperature (22-25 °C), and at least one year at elevated
temperature (50 °C).

Constitution as recommended results in a solution which is
chemically stable for at least 72 hours at room temperature.
Normal room light does not affect the stability of the constituted
solution.

Further dilution of the constituted solution with 5% Dextrose
Injection, USP, 5% Dextrose in 0.9% Sodium Chloride
Injection, USP, or 0.9% Sodium Chloride Injection, USP, does
not alter solution stability.

    CAUTION: The single-use lyophilized dosage
    form contains no antibacterial preservatives.
    Therefore, it is advised that the constituted
    product be discarded within 8 hours of initial
    entry.

Route of Administration: Intravenous