CHLORSULFAQUINOXALINE

NSC - 339004

SMILES: c1(ccc(cc1)S(=O)(=O)Nc1cnc2c(n1)cccc2Cl)N

Chemical Name: 4-Amino-N-[5-chloro-2-quinoxalinyl]-benzenesulfonamide

Other Names: Chloroquinoxaline Sulfonamide, CQS, Chloroquin Sulphon

CAS Registry Number: 97919-22-7

Molecular Formula: C14H11ClN4O2S      M.W.: 334.8

How Supplied: For injection, 500 mg, vial: supplied as a
yellow lyophilized powder with 750 mg of meglumine
(N-methylglucamine) in 20 mL amber vials.

Solution Preparation: 500 mg/vial: When constituted with 9.2
mL of Sterile Water for Injection, USP, each milliliter contains
50 mg of chlorsulfaquinoxaline and 75 mg of meglumine at pH
9.5 to 10.5.

Storage: Refrigerate the intact vials (2-8 °C).

Stability: Shelf life surveillance of the intact vials is ongoing.

Constitution as directed results in a solution that is physically
and chemically stable for at least 14 days at 0 °C and 25 °C.

Further dilution to a concentration of 1 mg/mL in 5% Dextrose
Injection, USP, or 0.9% Sodium Chloride Injection, USP, in
both glass and PVC containers resulted in stable solutions
exhibiting little or no decomposition in 14 days at 0 °C
and 25 °C.

    CAUTION: The single-use lyophilized dosage
    form contains no antibacterial preservatives.
    Therefore, it is advised that the constituted
    product be discarded within 8 hours of initial
    entry.

Route of Administration: Intravenous