This past weekend, more than 18,000 academic, industry, and government scientists; cancer survivors; philanthropic representatives; and industry professionals gathered in Chicago for the annual meeting of the American Association for Cancer Research. Founded in 1907, AACR is the world’s largest—and was the first—professional organization dedicated to advancing cancer research.Over its four days the meeting features hundreds of speakers and sessions, thousands of papers presented in poster sessions, and dozens more minisymposia. As you might expect, NCI-designated Cancer Centers and their dedication to important research were on full display.