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Tools for Researchers

Toolkit for Clinical Researchers

The Toolkit for Clinical Researchers is for NIDCR grant applicants or awardees planning to conduct clinical research.  The toolkit provides clinical research study start-up documents, documents to be used during the conduct of clinical research, and study close-out documents. 

Craniofacial Development Resources

FaceBase
An NIDCR-funded consortium designed to encourage collaboration among craniofacial researchers and accelerate craniofacial research by developing, integrating, and disseminating large datasets to the wider research community.  The consortium’s research projects and resulting datasets are described on the FaceBase website, as is the process for obtaining the data.   Access to FaceBase datasets is provided without cost to the scientific community.

Center for Inherited Disease Research (CIDR)
A trans-NIH genotyping service to support studies aimed at identifying genes that contribute to human disease

Mouse Mutation Database
A database of mutant mice for studies of human craniofacial disorders

Mutant Mouse Regional Resource Centers (MMRRC)
Trans-NIH repository and distribution centers of spontaneous and induced mutant mouse lines

Report on Global Strategies to Reduce the Health-Care Burden of Craniofacial Anomalies

The World Health Organization has published a report entitled, "Global Strategies to Reduce the Health-Care Burden of Craniofacial Anomalies."

NIDCR/CDC Dental, Oral and Craniofacial Data Resource Data Center

Search the Dental, Oral and Craniofacial Data Resource Center for oral health surveys--including procedures used and survey questions asked--or generate rapid statistical analyses of selected dental and oral health data using the Data Query System (DQS).

Microbiology and Immunology Resources

Oral Pathogen Sequence Relational Database
A specialized database at the Los Alamos National Laboratory featuring multiple search and annotation features for the analysis of oral microbial genomes.

Microbial Large-Scale DNA Sequencing Projects

Ribosomal Database Project-II Release 9
The Ribosomal Database Project (RDP) provides ribosome related data and services to the scientific community, including online data analysis and aligned and annotated 16S rRNA sequences. Release 9 contains 114,231 aligned and annotated bacterial small-subunit rRNA sequences, and is updated frequently.

Comprehensive Candida Albicans Database
NIDCR grantees recently launched a comprehensive database on the human fungal pathogen Candida albicans . Called the Candida Genome Database, this new online resource is freely available to all members of the research community. The database provides comprehensive literature curration that complements existing sequence-based annotation and provides centralized information, such as a gene-name registry, for the Candida research community. It will soon also offer a more extensive set of sequence retrieval and analysis tools. The database was described in detail in a recent special issue of the journal Nucleic Acids Research. See more about the Candida Albicans Database or visit the database web site at: www.candidagenome.org

Model Organisms


Model Organisms for Biomedical Research

This NIH web site provides information about mammalian and non-mammalian
models and other model organisms that are available for research.

Salivary Gland Tumors

A salivary gland tumor repository established by NIDCR to enable research to define the etiology and pathogenesis of these tumors.

Stem Cells

NIH Human Embryonic Stem Cell Registry
The NIH Human Embryonic Stem Cell Registry
lists the derivations of stem cells that are eligible for federal funding.

Tissue Arrays

Head and Neck Tissue Arrays

Overview

The  NIDCR is pleased to announce the Head and Neck Tissue Array (HNTA) Initiative. This initiative is a collaborative effort between the Oral and Pharyngeal Cancer Branch, NIDCR, the Tissue Array Research Program (TARP), National Cancer Institute (NCI) and several contributing centers in 8 countries, namely the United States, China, Thailand, Argentina, Mexico, South Africa, India, and Japan.  Each center has contributed a number of paraffin blocks from patients bearing head and neck squamous cell carcinomas, mainly oral cancer, as well as several other control tissues from non-neoplastic and neoplastic diseases.  A tissue microarray has been developed using samples from these sources. Investigators at both research intense and non-intense institutions, as well as foreign and domestic laboratories may request paraffin sections of the microarray. Although applicants are not required to be current NIDCR grantees, a high priority will be given to those who currently have an NIDCR grant studying head and neck carcinogenesis. Tissue microarray slides can be requested for exploratory, developmental as well as established research projects. Up to 4 array paraffin sections will be provided at no cost to a single investigator, but shipping charges will be covered by the investigator requesting the samples.  HNTAs and any related reagents are provided to the research community for research purposes only and their use for commercial purposes is prohibited.

For additional information, contact:

Alfredo A. Molinolo M.D., Ph.D.
Oral and Pharyngeal Cancer Branch
National Institute of Dental and Craniofacial Research
National Institutes of Health
Building 30, Room 213
Bethesda, MD 20892-0001
Tel: 301-402-7434
Fax: 301-402-0823
Email: amolinol@mail.nih.gov

This page last updated: January 30, 2012