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"head and neck cancer"

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Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer

This is an illustration of the head and neck region of the human body. Specific sites are labeled in the illustration: nasal antrum; oral cavity; esophagus; larynx; pharynx, including, nasophayrnx, oropharynx, and hypopharynx.

Health Impact of Head and Neck Cancer in the United States

This slide includes a table with three columns and four rows. Column 1, row 1: empty; column 2, row 1, early stage (stages I and II), column 3, row 1: locally advanced (stages III and IV); column 1, row 2: representation at diagnosis; column 2, row 2: 40%; column 3, row 2: 60%; column 1, row 3: definition; column 2, row 3: small primary tumor without lymph node involvement; column 3, row 3: large primary tumors, which may invade adjacent structures and/or spread to regional lymph nodes; column 1, row 4: typical treatment plan; column 2, row 4: single modality (surgery or radiation); column 3, row 4: combined modality. The slide includes a reference: Samson  DJ, et al. AHRQ Comparative Effectiveness Review No. 20. Available at: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/ ?pageaction=displayproduct&productID=447.

External-Beam Radiation Therapy for Head and Neck Cancer

Two-Dimensional Radiation Therapy and Three-Dimensional Conformal Radiation Therapy

This slide includes a table with two columns and four rows. Column 1, row 1: potential advantages. Column 2, row 1: potential disadvantages.Column 1, row 2: Higher dose delivered to tumor. Column 2, row 2: Higher total body dose. Column 1, row 3: Sparing of normal, surrounding tissue from radiation damage. Column 2, row 3: Increased risk of marginal miss and dose perturbation. Column 1, row 4: Decreased toxicity. Column 2, row 4: time and expense. A definition of abreviations is included on the slide: IMRT = intensity-modulated radiation therapy; 2DRT = two-dimensional radiation therapy; 3DCRT = three-dimensional conformal radiation therapy. A footnote includes the following references: (1) Ballivy O, Santamaria RG, Borbalas AL, et al. Clinical application of intensity-modulated radiotherapy for head and neck cancer. Clin Transl Oncol 2008;10:407-14; (2) Burri MK, Bevan A, Roach M III. Advances in radiation therapy: conventional to 3D, to IMRT, to 4D, and beyond. CA Cancer J Clin 2005;55:117-34; (3) Mendenhall WM, Amdur RJ, Palta JR. Intensity-modulated radiotherapy in the standard management of head and neck cancer: promises and pitfalls. J Clin Oncol 2006;24:2618-23; (4) Samson DJ, Ratko TA, Rothenberg BM, et al. Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, Comparative Effectiveness Review No. 20 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-based Practice Center under Contract No. 290-02-0026). Rockville, MD: Agency for Healthcare Research and Quality; May 2010. AHRQ Publication No. 10-EHC014-EF. Available at: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productID=447.

Potential Advantages and Disadvantages of IMRT When Compared With 2DRT and 3DCRT

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