A pilot study of a culturally targeted video intervention to increase participation of African American patients in cancer clinical trials.

Posted: Jun 21, 2012
Oncologist. 17. 5. 708-14.
KEYWORDS: Knowledge/Attitudes/Beliefs, Language or Cultural Barriers, Level of Clinical Trials Knowledge or Awareness, Attitudes, Consent, Black or African-American, TV


A video addressing attitudes toward clinical research increased participation of African Americans in therapeutic cancer trials.

Why this item may be useful

The authors developed a 15-minute culturally targeted video designed to influence attitudes toward cancer therapeutic clinical trials often expressed by African American patients. Intention to enroll was the primary outcome of the study, which also examined changes in attitudes. Among respondents who initially expressed unwillingness to participate in a trial (59 percent of the sample), 66 percent changed their minds after viewing the video; 36 percent of the overall sample changed their minds. Positive post-test changes were also found with regard to all six attitudinal barriers addressed in the video.


  • A questionnaire was administered before and after patients viewed the video.
  • In addition to asking about attitudes and experiences related to clinical research, the questionnaire asked whether the patient was likely to participate in a trial.
  • A total of 108 patients responded to the study questionnaire.
  • The survey provided evidence that the video is potentially useful across all cancer types and a variety of therapeutic interventions.
  • The interviewer-administered questionnaire provides an opportunity to reach African American patients with low levels of literacy, which may be associated with lack of knowledge about clinical trials.