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Colon and Rectal Cancer: Prevention, Genetics, Causes

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Prevention

  • Colorectal Cancer Prevention (PDQ®)
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    Expert-reviewed information summary about factors that may influence the risk of developing colorectal cancer and about research aimed at the prevention of this disease.
  • Clinical Trials to Prevent Colon Cancer
    Check for colon cancer prevention trials from NCI's list of cancer clinical trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.
  • Clinical Trials to Prevent Rectal Cancer
    Check for rectal cancer prevention trials from NCI's list of cancer clinical trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.
  • Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk
    Findings from the first large clinical trial of its kind indicate that taking high doses of aspirin daily for at least 2 years substantially reduces the risk of colorectal cancer among people at increased risk of the disease.
  • Celecoxib Reduces Risk of Precancerous Colorectal Polyps: Five-Year Results of APC Trial
    The five-year results of the Adenoma Prevention with Celecoxib (APC) trial indicate that two years after daily use of celecoxib (Celebrex®) has ended, there continues to be a modest reduction in the recurrence of colorectal polyps, according to a presentation at the 2008 American Association for Cancer Research annual meeting.

Genetics

  • Genetics of Colorectal Cancer (PDQ®)
    [ health professional ]
    Expert-reviewed information summary about the genetics of colorectal cancer, including information about specific genes and family cancer syndromes. The summary also contains information about screening for colorectal cancer and research aimed at prevention of this disease. Psychosocial issues associated with genetic testing and counseling of individuals who may have hereditary colorectal cancer syndrome are also discussed.
  • Breast and Colon Cancer Family Registries
    Two international family registries on breast and colon cancers offer concerned individuals the opportunity to participate in research, and investigators opportunities to conduct valuable research.
  • Understanding Gene Testing
    Illustrates what genes are, explains how mutations occur and are identified within genes, and discusses the benefits and limitations of gene testing for cancer and other disorders.
  • Cancer Genetics Services Directory
    Directory of professionals who provide services related to cancer genetic risk assessment, counseling, and testing.

Causes and Risk Factors