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Program Operations Branch

Research Summary

The Program Operations Branch (POB) — headed by Branch Chief Cynthia Smith, Ph.D. ("/Rhythmyx/assembler/render?sys_contentid=50560&sys_revision=2&sys_variantid=1173&sys_context=0&sys_authtype=0&sys_siteid=&sys_folderid=" sys_dependentvariantid="1173" sys_dependentid="50560" inlinetype="rxhyperlink" rxinlineslot="103" sys_dependentid="50560" sys_siteid="" sys_folderid="")— provides critical scientific and information technology expertise necessary to conduct and support the National Toxicology Program (NTP)  research efforts.  POB staff members are responsible for the following general functions:


  • Acquiring and validating new methods and capabilities to address specific requirements for NTP studies.
  • Advising NTP staff and directing the work of NTP contract study laboratories conducting general toxicology, developmental neurotoxicology and carcinogenicity studies.
  • Providing expertise, direction, and oversight for a number of NTP support functions including studies of absorption, distribution, metabolism and excretion (ADME) and toxicokinetics, analytical chemistry and quality assurance.
  • Conducting activities related to maintaining and developing databases for NTP studies as well as data capture and retrieval systems.
  • Receiving, tracking, maintaining, and disseminating NTP documents and data for both the NTP public and internal websites.


Program Operations Branch Logo NTP: Chemistry, ADME, Toxicology, Quality Assurance, Information

To facilitate these activities, the Program Operations Branch is organized into the following:


  • Chemistry and ADME (Absorption, Distribution, Metabolism and Excretion) Resources Group (CARG)
  • Study Management Workgroup (SMW)
  • Information and Data Management Workgroup (IDMW).


These groups work with a variety of NTP staff to accomplish program goals. Please see specific activities and interests of each section on the Organization ("/Rhythmyx/assembler/render?sys_contentid=52081&sys_revision=1&sys_variantid=639&sys_context=0&sys_authtype=0&sys_siteid=&sys_folderid=" sys_dependentvariantid="639" sys_dependentid="52081" inlinetype="rxhyperlink" rxinlineslot="103" sys_dependentid="52081" sys_siteid="" sys_folderid="") page.


Scientific Support Staff

Bonnie Allen
Administrative Specialist

Tel (919) 541-3449
Fax (301)-480-3231

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