Translational Genomics and Molecular Epidemiology of Cancer and Infection

The Prokunina-Olsson group within the LTG utilizes the results of Genome-Wide Association Studies (GWAS) for several human cancers and infectious diseases for identification of genetic risk factors and molecular phenotypes associated with these traits. The scope of interests includes but is not limited to human genetics (fine mapping, association studies, sequencing, mutation identification, bioinformatics, biostatistics, and epidemiology), functional genomics (expression studies, reporter assays, cell biology, genomics, epigenetics), and the merger of the two fields - correlation of genotypes and molecular phenotypes. The goal of the studies is to identify heritable genetic variants contributing to increased risk of cancer, provide functional understanding of their mechanism of action, and use these findings for disease prediction, diagnostics, and treatment. Recent papers that illustrate the group's work - Kohaar et. al, Genetic variant as a selection marker for anti-prostate stem cell antigen Immunotherapy of bladder cancer, JNCI, 2012; Prokunina-Olsson et. al, A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus, Nat Gen, 2013.

The successful candidate to join the multidisciplinary team is a talented and motivated individual with a doctoral degree in genetics, molecular biology, bioinformatics, epidemiology, or a closely related subject and no more than 5 years of postdoctoral experience. Salary is highly competitive and will be set commensurate with experience and accomplishments.

Employer Name: The Laboratory of Translational Genomics (LTG), Division of Cancer Epidemiology and Genetics at the National Cancer Institute National Cancer Institute

Position Location: Gaithersburg, MD

To Apply:

Submit cover letter, list of publications, and CV to Dr. Ludmila Prokunina-Olsson, prokuninal@mail.nih.gov.

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.