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Researchers Uncover New Target for Anticancer Drug Development Link to external Web site
October 25, 2012 • University of Colorado at Boulder

Protein's Flexible Tail Helps Form Scaffold for Telomerase Assembly Link to external Web site
June 18, 2012 • University of California, Los Angeles

Roundworms Provide Tool for Studying How Cancers Override Cellular Growth Controls Based on Wearing Down Telomeres Link to external Web site
March 21, 2012 • Salk Institute for Biological Studies

How DNA Damage Checkpoint Enzymes Are Involved in Stable Maintenance of Telomeres Link to external Web site
November 23, 2011 • University of Illinois at Chicago

DNA Reshuffling in Worms Offers Insight on How Tumors Develop Link to external Web site
April 21, 2011 • University of North Carolina

Scientists Reveal a New Ending to an Old 'Tail' Link to external Web site
April 21, 2011 • Salk Institute

New 3-D Model of RNA 'Core Domain' of Enzyme Telomerase May Offer Clues to Cancer, Aging Link to external Web site
November 3, 2010 • UCLA Newsroom

Protein Shows Surprising Range of Functions Link to external Web site
August 13, 2009 • University of Texas M. D. Anderson Cancer Center

A protein known to regulate gene expression also protects the tips of chromosomes and is involved in protein stability, NIGMS-funded researchers report.

Telomeres Resemble DNA Fragile Sites Link to external Web site
July 9, 2009 • Rockefeller University

New NIGMS-supported research suggests a striking similarity between telomeres and common fragile sites, parts of the genome where breaks tend to occur.

Cell Death and the Ends of Chromosomes Link to external Web site
October 1, 2008 • University of Utah

NIGMS-funded biologists have shown that losing just one telomere can lead to many abnormalities in a cell's chromosomes.

Twice the Telomere Options in Roundworms Link to external Web site
March 6, 2008 • Salk Institute

NIGMS-funded researchers have discovered that C. elegans can cap their chromosomes with two different types of telomeres, a finding with implications for aging and cancer.

Mechanism Links Aging and Cancer Link to external Web site
February 5, 2007 • Salk Institute

In studying the chromosomes of patients with the premature aging disease Werner Syndrome, NIGMS-funded researchers have shown that rebuilding the chromosome tips blocks genetic damage associated with both aging and cancer.

NIGMS-Supported Research Garners Top U.S. Science Prize
September 18, 2006 • National Institute of General Medical Sciences

The 2006 Albert Lasker Award for Basic Medical Research went to Elizabeth Blackburn, Carol Greider, and Jack Szostak for their prediction and discovery of telomerase. Joseph Gall received a special achievement award for his pioneering work on chromosome structure and function, and for championing women in science.

Lasker Award for Special Achievement in Medical Science Link to external Web site
September 17, 2006 • Carnegie Institution

Long-time NIGMS grantee Joseph G. Gall has won a Lasker Award for his study of chromosome structure and function, his invention of an important technique, and his championing of women in science.

NIGMS Grantee Wins Lasker Award Link to external Web site
September 17, 2006 • Johns Hopkins Medical Institutions

NIGMS grantee Carol Greider was among the winners of this year's Lasker Award for her work on telomerase, the enzyme that maintains the ends of chromosomes.

Biochemists Uncover Structure of Major Piece of Telomerase Link to external Web site
March 9, 2005 • University of California, Los Angeles

NIGMS-funded biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres—the small protective caps on the ends of chromosomes—allowing DNA ends to be copied completely when cells are replicated.

Psychological Stress and Disease: UCSF-led Study Suggests Connection
November 29, 2004 • University of California - San Francisco

Increasing scientific evidence suggests that prolonged pshycological stress takes its toll on the body. Now, NIGMS-supported scientists report that psychological stress may exact its toll, at least in part, by affecting molecules believed to play a key role in cellular aging and possibly, disease.

This page last reviewed on January 25, 2012