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The Human Genome Project was marked by accelerated progress. In June 2000, the rough draft of the human genome was completed a year ahead of schedule. In February 2001, the working draft was completed, and special issues of Science and Nature containing the working draft sequence and analysis were published. Additional papers were published in April 2003 when the project was completed..

The project's first 5-year plan, intended to guide research in FYs 1990-1995, was revised in 1993 due to unexpected progress, and the second plan outlined goals through FY 1998. The third and final plan [Science, 23 October 1998] was developed during a series of  DOE and NIH workshops. Some 18 countries have participated in the worldwide effort, with significant contributions from the Sanger Center in the United Kingdom and research centers in Germany, France, and Japan.

Human Genome Project Goals and Completion Dates

Archival Documents

Five-Year Plans:

• Third 5-Year Plan (1998-2003)
  • Highlights
  • Detailed List of Goals
  • Plan as presented in the October 23, 1998 Science
  • Oct. 1999 HGN article about plan acceleration: HGP Leaders Confirm Accelerated Timetable for Draft Sequence
• Second 5-Year Research Goals of the U.S. Human Genome Project (FY 1993-1998)
• Original 5-Year Research Goals (FY 1990-1995)
• Synopsis of Original 5-Year Research Goals
• Timeline of Major Events in the U.S. Human Genome Project and Related Projects

5-Year Planning Workshops:

• DOE BERAC Advisory Subcommittee Meeting Proceedings (1998)
• JASON Evaluation Report of the Human Genome Project (1997)
• Summary Report on the DOE/NIH Genome Informatics Meeting (1998)
• ELSI Research Planning and Evaluation Group (ERPEG) (1997)