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Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRI) for Adults With Hypertension

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Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRI) for Adults with Hypertension

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Background: Prevalence

Keywords: prevalence | hypertension | risk factor | heart | kidneys
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Background: Treatment

Keywords: treatment | hypertension | diet | exercise | weight | antihypertensive medication
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Background: Pharmacological Blockade of the Renin-Angiotensin System

Keywords: renin-angiotensin system | pharmacological blockade | angiotensinogen | angiotensin converting enzyme | angiotensin II
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Background: Drugs Targeting The Renin System May Not Be Clinically Equivalent

Keywords: renin system | ACEIs | ARBs | angiotensin II | DRI | aliskiren
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Rationale for Update

Keywords: systematic review | comparative effectiveness | ACEI | ARB | hypertension | aliskiren | DRI
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Agency for Healthcare Research and Quality (AHRQ) Comparative Effectiveness Review (CER) Development

Keywords: Agency for Healthcare Research and Quality (AHRQ) | comparative effectiveness | nomination | systematic review | clinician | consumer
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Rating the Strength of Evidence From the CER

Keywords: strength of evidence | CER | confidence | research
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Number of Studies Evaluating Various Treatment Options

Keywords: treatment | ACEIs | ARBs | DRI | aliskiren | number of studies
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Evidence of Benefits: Blood Pressure-Lowering Effects

Keywords: blood pressure | ACEIs | ARBs | DRI | aliskiren | ramipril | losartan
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Evidence of Benefits: Clinical Outcomes

Keywords: clinical outcomes | ACEIs | ARBs | mortality | cardiovascular events | serum lipid levels | renal disease | quality of life
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Evidence on Adverse Effects

Keywords: adverse effects | cough | persistence | withdrawals
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