Archive of Historical and Replaced Materials

OHRP has placed a number of historical and superseded documents in a separate archive area.  These documents are accessible to the public for research and informational purposes, but should not be regarded as reflecting current HHS or OHRP policy.  

OHRP Archived Materials include, but are not limited to:

• Foundational and Historical Documents, including
  • Nuremberg Code 
  • Federal Register Notices 1973-2008
  • National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (1974-1978
    • Reports of the National Commission
    • Belmont Archive
      • Celebration of 25th Anniversary of the Belmont Report
      • Belmont Oral History Archive of interviews with National Commission members and staff
  • IRB Guidebook
  • Henry Beecher 1966 NEJM Article "Ethics and Clinical Research"
• Guidance Documents No Longer in Effect
• Requests for Public Comment
• National Human Research Protections Advisory Committee (NHRPAC) Materials (2000-2003)
• Secretary’s Advisory Committee on Human Research Protections (SACHRP) Materials (2003-2007)
• Children in Research
• Conflicts of Interest
• Alternative Models of IRB Review

Searches of historical and superseded documents are conducted on the archive area homepage.  Please note that search results in the archive area include only historical and superseded documents.  This is intended to help avoid confusion with current policy and guidance documents.