H5N1 Genetic Changes Inventory: A Tool for International Surveillance

Highly pathogenic avian influenza (HPAI) (H5N1) viruses have evolved rapidly since they were first identified in humans in 1997. Because H5N1 viruses are always changing, CDC and other public health agencies look for genetic changes in H5N1 viruses that may impact how HPAI H5N1 viruses spread from person to person or their susceptibility to influenza antiviral drugs. To support international surveillance and pandemic preparedness efforts for avian influenza A H5N1 viruses, CDC has compiled an inventory of known H5N1 genetic changes.

For Health Professionals

• H5N1 Inventory Preamble
  The preamble offers background information about purpose and development of the H5N1 Inventory
• H5N1 Genetic Changes Inventory: A Tool for Influenza Surveillance and Preparedness
  This is the actual list of all genetic changes found in H5N1 viruses as of June 26, 2012.

For the Public

• H5N1 Genetic Changes Inventory: Questions & Answers
  Information for the public about the H5N1 Inventory