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Bioscience & Health Programs & Projects

(showing 16 - 30 of 116)
High-Precision Isotopic Reference Materials
Last Updated Date: 10/09/2012

Recent innovative advances in the design and manufacture of isotope ratio mass spectrometers (IRMS) have revolutionized the study of natural and … more

Fundamental Chemical Metrology
Last Updated Date: 10/09/2012

The Analytical Chemistry Division serves as the Nation’s reference laboratory for chemical compositional measurements and standards to … more

Potential Primary Measurement Tool for the Quantification of DNA
Last Updated Date: 10/09/2012

The accurate mass determination of DNA and other nucleic acids is of critical importance in many clinical diagnoses and in forensic and molecular … more

Micronutrients Measurement Quality Assurance Program
Last Updated Date: 10/09/2012

The Micronutrients Measurement Quality Assurance Program , coordinated by the Analytical Chemistry Division, supports measurement technology for … more

Development of a Standard Reference Material for Vitamin D in Human Serum
Last Updated Date: 10/09/2012

The prevalence of vitamin D deficiency/insufficiency within the general population is an area of concern. Vitamin D status is generally assessed … more

Development of Standard Reference Materials for Vitamins B6 and B12 in Human Serum
Last Updated Date: 10/09/2012

Vitamins are essential to normal functioning of the human body because they serve as co-factors for important biological processes. Deficiencies … more

Resonating Platforms for Nanomaterial Analysis
Last Updated Date: 10/09/2012

Our goal is to develop quartz crystal microbalance (QCM) instrumentation and advanced oscillators with enhanced sensitivity to … more

Fate of Nanoparticles in Neural Environments
Last Updated Date: 10/09/2012

Our goal is to develop an advanced in vitro system for nano-neurotoxicology that employs neural progenitor cells and tissue-engineering hydrogels. … more

Instrumented Bioreactors
Last Updated Date: 10/09/2012

Our goal is to develop novel bioreactors that combine mechanical stimulation with integrated sensing to enable real-time optimization of the … more

Metallomics:  A Multidisciplinary Approach for the Qualitative and Quantitative Determination of Proteins and Metalloproteins Used as Health and Disease Markers
Last Updated Date: 10/09/2012

As healthcare shifts from management of disease to management of health, there will be a necessary shift toward development of quantitative health … more

Development of Proteomics-Based Methods for Protein Quantification
Last Updated Date: 10/09/2012

NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to … more

Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers
Last Updated Date: 10/09/2012

Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these … more

Improving Measurement Quality in Clinical Proteomics
Last Updated Date: 10/09/2012

Through collaboration with academic and government institutes, NIST is critically evaluating and attempting to improve measurement quality in … more

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum
Last Updated Date: 10/09/2012

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac … more

Development of a Reference Measurement Procedure for C-Reactive Protein in Human Serum
Last Updated Date: 10/09/2012

C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests … more

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