INTRODUCTION
Nora D. Volkow, M.D.

ADDICTION AND OBESITY-BRAIN SYSTEM COMMONALITIES
What Marijuana Is Teaching Us About Food Intake and Body Weight Regulation
Daniele Piomelli, Ph.D.

Neural Systems Recruited by Drugs and Food: Focus on Corticostriatal-Hypothalamic Integration
Ann E. Kelley, Ph.D.

Brain Processing of Food-Related Stimuli With Relevance to the Control of Appetite: Taste, Olfactory, Texture, and Visual Representations of Food in the Brain
Edmund T. Rolls, D.Sc., D.Phil.

Common Brain Mechanisms in Addiction and Obesity
Nora D. Volkow, M.D.

KEYNOTE SPEECH: JACOB P. WALETZKY MEMORIAL AWARD RECIPIENT
Introduction: Robert Malenka, M.D., Ph.D., Chair of the 2005 Jacob P. Waletzky
Memorial Award Selection Committee, SfN

Experience-Dependent Alterations in the Function of Brain Reward Systems: The Role of CREB
William A. Carlezon Jr., Ph.D.

NEUROBIOLOGICAL BASIS FOR CO-OCCURRING SUBSTANCE ABUSE AND MENTAL ILLNESS
Human Genetic Determinants of Schizophrenia and Nicotine Addiction
Sherry Leonard, Ph.D.

Animal Models of Schizophrenia and Depression: Studies on the Neurobiological Basis for Comorbidity With Drug and Alcohol Abuse
R. Andrew Chambers, M.D.

Nicotine-Induced Sensitization in ADHD
Jean A. King, Ph.D.

Use Increases Risk of Adult Psychosis Only in Those With Specific COMT Genotypes
Robin M. Murray, M.D., D.Sc.


mGluR: A SUBSTRATE IN THE NEUROBIOLOGY OF ADDICTION
Metabotropic Glutamate 5 Receptors: Role in Drug Self-Administration and in Regulating the Activity of Brain Reward Systems
Paul J. Kenny, Ph.D.

mGluR-Homer Interactions: A Cellular Mediator of Alcohol Reward
Karen K. Szumlinski, Ph.D.

mGluR Regulation of Endocannabinoid Release From Midbrain Dopamine Neurons
Carl R. Lupica, Ph.D.


RECONSOLIDATION OF MEMORY: A NEW APPROACH TO TREAT DRUG ADDICTION?
The Labile Nature of Consolidation Theory
Karim Nader, Ph.D.

Disrupting Memories Induced by Drugs of Abuse
Christina M. Alberini, Ph.D.

Disrupting Reconsolidation of Drug Memories: Potential Treatment Target for Attenuating Drug-Seeking and Relapse Elicited by Drug-Associated Stimuli
Barry J. Everitt, Sc.D.

Reconsolidation, Cocaine, and Matrix Metalloproteinases
Barbara A. Sorg, Ph.D.


ADOLESCENT DRUG ABUSE: BRAIN DEVELOPMENT, COGNITION, AND VULNERABILITY
Evidence for Enhanced Neurobiological Vulnerability to Nicotine During Periadolescence in Rats
Pier Vincenzo Piazza, M.D., Ph.D.

Adolescent Brain and Behavior: Age-Related Sensitivities to Natural Rewards and Drugs
Linda P. Spear, Ph.D.

Vulnerabilities in Neurocognitive Processes in Adolescence
Beatriz Luna, Ph.D.

Brain Development in Healthy and Impulsive-Inattentive Children
Judith L. Rapoport, M.D.