NIH and Government Programs and Initiatives in Biomedical Informatics and Computational Biology (BICB)
Maintained by the BISTI consortium. Send comments, suggestions to Peter Lyster.
This is a list of NIH programs and initiatives with a preponderance of or a significant component of biomedical informatics and computational biology (BICB). A Program is an ongoing effort with prior and possibly future funding opportunity announcements, while an Initiative specifically refers to an active FOA*. Some P&I appear twice.
*Active FOAs are identified by (A)
Tips on writing a grant in Biomedical Informatics and Computational Biology.
How to Approach NIH for Support for a Computational Project.
For an update on funding of computational grant applications at NIH read the recent editorial in Biocomputational Review.
View a link to the summary of NIH programs in Systems Biology.
Broad-based BISTI initiatives
- BREAKING NEWS: The broad-based BISTI Innovations R01, R21, SBIR/STTR have been extended until September 8, 2013: NOT-GM-12-112, NOT-GM-12-113, NOT-GM-12-114, and NOT-GM-12-115.
- NSF-NIH Interagency Initiative: Core Techniques and Technologies for Advancing Big Data Science and Engineering (BIGDATA) (NOT-GM-12-109) (A): May 8, 11 AM Big Data Webinar
- The Biomedical Information Science and Technology Initiative (BISTI) (A)
- BISTI Innovations in Biomedical Computational Science and Technology (R01) – PAR-09-218; (R21) – PAR-09-219; BISTI keeps a list of R01 contact program staff (A)
- BISTI Continued Development and Maintenance of Software (R01) – PAR-11-028 (A)
- BISTI Innovations in Biomedical Computational Science and Technology Initiative (SBIR [R43/R44]) – PAR-09-220 ; (STTR [R41/42])- PAR-09-220; BISTI keeps a list of SBIR/STTR contact program staff (A)
- Collaborations with National Centers for Biomedical Computing (R01) – PAR-12-001 (A). The R21 Exploratory FOA has been discontinued.
The Innovations program for regular grant applications (R01) (PAR-09-218) and exploratory high risk/high reward grant applications (R21) (PAR-08-219), and the program contact persons are at http://www.bisti.nih.gov/R01-contacts.cfm. The initiatives use standard receipt dates. As mentioned above, there should be a preponderance of effort in computing. Of course it is appropriate to budget some moneys for experimental data acquisition in support of the computational research. New investigators under these PAs are eligible for shortened review cycle http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-07-083.html.
The Innovations program for SBIR/STTRs are (PAR-09-220) and (PAR-09-221), which use standard receipt dates, and the program contact persons are at http://www.bisti.nih.gov/SBIR-contacts.cfm. For additional information, the NIH SBIR Funding Opportunities page offers a wealth of information dealing with SBIR/STTR program (not just computing) http://grants.nih.gov/grants/Funding/sbir.htm.
Broad-based or multi Institute Programs and Initiatives
- Research Project Grant (Parent R01) – PA-11-260, NIH Exploratory Developmental Research Grant Program (R21) – PA-10-069, and the Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications – PA-12-089. The majority of computational applications go to mainline NIH study sections (BDMA, MABS, BCHI, NT, GCAT, MSFD, BMRD, BMIT, MEDI, and MIS) (A)
- NEW: Modeling Social Behavior (R01) – RFA-GM-13-006 (A)
- Interagency Modeling and Analysis Group (IMAG) and IMAG New Funding Opportunities (A)
- Collaborative Research in Computational Neuroscience (CRCNS): A Joint NSF-NIH initiative: NSF-11-505 (A)
- Predictive Multiscale Models for Biomedical, Biological, Environmental and Clinical Research (Interagency U01)—PAR-11-203 (A)
- IMAG Population Modeling Funding Announcements (A)
- OBSSR Funding Opportunity Announcements in Systems Science (A)
- Basic Behavioral and Social Sciences Network (OppNet) (A)
- Social Network Analysis and Health (R01) – PAR-10-145 (A)
- Systems Science and Health in the Behavioral and Social Sciences (R01) PAR-11-314 (R21) PAR-11-315 (A)
- Social Network Analysis and Health, One receipt date per year (R01) PAR-10-145 (R21) PAR-10-146 (A)
- Dissemination and Implementation Research in Health, PAR-10-038 (R01), PAR-10-039 (R03), PAR-10-040 (R21) (A)
- Mechanisms Underlying the Links between Psychosocial Stress, Aging, the Brain and the Body (R01) -- PA-09-216 (A)
- The National Center for Research Resources (NCRR) program for Biomedical Technology Research Centers (BTRC). Some of these have computational focus. The National Institute of Biomedical Imaging and Bioengineering also has a program in Biotechnology Resource Centers. See Announcement for current status. (A)
- Climate Change and Health: Assessing and Modeling Population Vulnerability to Climate Change (R21) – PAR-10-235 (A)
- Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01) – PAR-10-141 (A)
- New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01) – PAR-10-142
- Bioengineering Research Partnerships (R01) – PAR-10-234 (A)
- Bioengineering Research Grants (R01) – PA-10-009 (A)
- Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21) – PA-10-010 (A)
- Notice of Availability of Administrative Supplements for the U.S.-JAPAN Brain Research Cooperative Program – U.S. Component – NOT-NS-10-014 (A)
- Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) – RFA-GM-11-003 RETIRED and replaced by
- NIH Director’s Transformative Research Awards (R01) – RFA-RM-11-006 (A)
- Spatial Uncertainty: Data, Modeling, and Communication (R01) – PA-11-238, (R21) – PA-11-239, (R03) – PA-11-240 (A)
- Lab to Marketplace: Tools for Brain and Behavioral Research (SBIR[R43/44]) – PA-11-134 (A)
- SHIFT Award: Small Business Helping Investigators to Fuel the Translation of Scientific Discoveries [SBIR: R43/R44] – PAR-10-122 (A)
Institute Programs or Initiatives
- NEW from NCI: Revisions for Early-Stage Development of Informatics Technology (R01) – PAR-12-286 (A)
- NEW from NCI: Revisions for Early-Stage Development of Informatics Technology (P01) – PAR-12-290 (A)
- NEW from NCI: Revisions for Early-Stage Development of Informatics Technology (U01) (up to $150,000 DC/year for 2 years) – PAR-12-289 (A)
- NEW from NCI: Early-Stage Development of Informatics Technology (U01) (up to $250,000 DC/year for 3 years) – PAR-12-288 (A)
- NEW from NCI: Advanced Development of Informatics Technology (U24) (up to $500,000 DC/year for 5 years) – PAR-12-287 (A)
- NIDDK Interconnectivity Network Coordinating Unit (U24) – RFA-DK-11-030 (A)
- National Center for Biotechnology Information (NCBI)
- Informatics components of the NIH Intramural Program
- Center for Information Technology Division of Computational Bioscience
- Cancer Bioinformatics Grid (caBIG)
- Biomedical Informatics Research Network (BIRN)
- Neuroimaging Informatics Technology Initiative (NIfTI)
- Genetic Association Information Network (GAIN)
- NIAID Bioinformatics Resource Centers (BRC)
- NIAID Division of Allergy, Immunology, and Transplantation Centers and Resources (A)
- Clinical and Translational Science Awards(CTSA) Informatics Key Functional Committee
- NLM Grant Programs in Informatics and Knowledge Management (A)
- NLM Express Research Grants in Biomedical Informatics (R01) – PAR-11-208
- NHGRI Genome Informatics Program
- Genome Resource Grants for Community Resource Projects (U41) – PAR-11-095 (A)
- Centers of Excellence in Genomics Science (NHGRI) CEGS – PAR-10-202 (A)
- 1000 Genomes Project
- NIGMS National Centers for Systems Biology (P50) - PAR-10-200 To be reissued in March 2012
- NHLBI Mechanistic Pathways Linking Psychological Stress and Behavior (R01) – RFA-HL-12-037 (A)
- NHLBI Systems Biology Collaborations (R01) - PAR-09-214 (A)
- Cardiovascular Research Grid (CVRG) Wiki
- Collaborative Research in Integrative Cancer Biology and the Tumor Microenvironment (U01) – PAR-11-146 (A)
- Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01) – PAR-11-150 (A)
- Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R01) – PA-10-025, (R21) – PA-10-026 (A)
- A Systems Biology Approach for Infectious Diseases Research
- Physical Science in Oncology Program
- The Cancer Genome Atlas
- Limited Pilot for NIGMS Legacy Community-Wide Scientific Resources (R24) – PAR-10-261 (A)
- Modeling the Scientific Workforce (U01) – RFA-GM-11-007
- Pilot Studies to Develop and Test Novel, Low- Cost Methods for the Conduct of Clinical Trials (R01) – RFA-HL-12-019
- Virtual Reality Technologies for Research and Education in Obesity and Diabetes (R43/R44) – RFA-HL-12-020, (R41/R42) – RFA-HL-12-024 (A)
- Modeling of Infectious Disease Agent Systems (MIDAS) has recurring FOAs
- The NIGMS also has a program in support of Program Project Grants (P01) PAR-11-220 (A)
- Technology Development for Protein Modeling (R01) – PAR-10-076 ; (P01) – PAR-10-075 (A)
- NIGMS Administrative Supplements for Collaborative Science NOT-GM-11-105 (A)
- Pediatric Neuroimaging Initiative
- Theoretical and Computational Neuroscience Program (A)
- Cutting-Edge Basic Research Awards (CEBRA) (R21) – PAR-12-086 (A)
- Data Concepts and Terminology Standards for Clinical Research and Drug Development (R24) FDA -- PAR-11-209 (A)
- Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery (R01) – PA-09-004 (A)
Common Fund and Neuroscience Blueprint Programs or Initiatives
- The NIH Common Fund
- Common Fund High-Risk Research, including the NIH Director’s Early Independence Awards (DP5), Transformative Research Awards (R01), New Innovator’s Awards (DP2), and Pioneer’s Awards (DP1)
- NEW: NIH Health Care Systems (HCS) Research Collaboratory – Coordinating Center (U54) – RFA-RM-11-021 and Pragmatic Trials Demonstration Projects (UH2/UH3) RFA-RM-11-002 (A)
- Single Cell Analysis; Studies to evaluate cellular heterogeneity using transcriptional profiling of single cells (U01) – RFA-RM-11-013 (A); Exceptionally Innovative Tools and Technologies for Single Cell Analysis (R21) – RFA-RM-11-014 (A); Accelerating the Integration and Translation of Technologies to Characterize Biological Processes at the Single Cell Level (R01) – RFA-RM-11-015 (A)
- National Centers for Biomedical Computing (NCBC)
- Health Care Economics
- Exploratory Centers for Cheminformatics Research
- Patient Reported Outcomes Measurement System (PROMIS)
- Technology Centers for Networks and Pathways (TCNP)
- Nanomedicine Initiative
- Epigenomics
- Library of Integrated Networked-Based Cellular Signatures (LINCS)
- Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC)
- Neuroscience Information Framework (NIF)
- The Human Connectome Project
- Health Economics
Training Opportunities
- Short Courses on Mathematical, Statistical, and Computational Tools for Studying Biological Systems (R25) – PA-11-351 (A)
- Mentored Quantitative Research Development Award (K25) – PA-11-196 (A)
- Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) – PA-11-184 (A)
- NIH Pathway to Independence (PI) Award (K99/R00) – PA-11-197 (A)
- Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32) – PA-11-113 (A)
- NLM Independent Career Development Award for Biomedical Informatics – (K22) PAR-10-195
Multi-Agency Programs and Initiatives
- Interagency Modeling and Analysis Group (IMAG) (A)
- Collaborative Research in Computational Neuroscience (CRCNS) (R01) A Joint NSF-NIH initiative: NSF-11-505 (A)
- Joint DMS/NIGMS Initiative to Support Research in the Area of Mathematical Biology (A) to be reissued. See also NIGMS link.
- Petascale Computing Resource Allocations (PRAC), NSF Program Solicitation 08-529
- Advancing Health Services through System Modeling Research – 12-515 (A)
Other Agency, Foundation, and International Efforts
- NEW: NSF Smart Health and Wellbeing (SHB)
- NSF Dynamics of Coupled Natural and Human Systems (CNH)
- NSF Office of Cyberinfrastructure (OCI) and Directorate for Biological Sciences (BIO)
- DOE Genomics: GTL
- NSF Methodology, Measurement, and Statistics (MMS) NSF12-510
- NSF Science of Science and Innovation Policy (SciSIP)
- NSF Cognitive Neuroscience NSF09-563
- NSF Perception, Action, and Cognition
- NSF Science, Engineering, and Education for Sustainability NSF-Wide Investment (SEES)
- NSF Social-computational systems (SoCS) NSF10-600
- NSF Cyber-enabled discovery and innovation (CDI) NSF11-502
- NSF Advances Biological Informatics (ABI) NSF10-567
- EPA funding opportunities
- The Virtual Physiological Human
- Notice of Availability of Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program – U.S. Component
If you have any questions about the programs, feel to email: Peter Lyster
Updated 02/08/2012