Decision making for cancer clinical trial participation: a systematic review.
The three main factors that influence the decision-making process for participation in cancer clinical trials are patient, provider, and treatment factors.
Why this item may be useful
More research on the decision-making process for participation in cancer clinical trials is needed. A better understanding of the decision-making process may help improve patient-provider communication and create interventions to facilitate decision-making, leading to increased clinical trial participation.
- The authors reviewed relevant studies published on PubMed since 2004.
- Factors that influence clinical trial participation decision making among patients with cancer were identified.
- Patient factors include clinical trial information, decision-making style preferences, decisional regret, disease characteristics, optimism, quality of life, relative health status, satisfaction with decision making, sociodemographic profile, spirituality, trust in God or medicine, and understanding of purpose.
- Provider factors were clinical trial information, coercive pressure, communication, and recommendation for participation.
- Treatment factors were alternative treatment options, benefits and risks, clinical trial information, phase of cancer clinical trial, and time and travel considerations.