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The Computer Science Branch (CSB) is part of the Lister Hill National Center for Biomedical Communications, a research and development division of the U.S. National Library of Medicine. CSB applies techniques of computer science and information science to problems in the representation, retrieval and manipulation of biomedical knowledge.

CSB projects involve both basic and applied research. Current research areas include intelligent gateway systems for simultaneous searching in disparate databases; knowledge acquisition, management, representation, and structure; medical record de-identification, acquisition, and management in strict conformance with privacy restrictions; the merging of thesauri and other medical controlled vocabularies as well as interoperability issues; and embedded intelligence systems that combine local reasoning with access to large-scale online databanks.

Past research projects conducted by the CSB have included work in the areas of object-oriented databases, full-text retrieval systems, intelligent agent design, human-machine interfaces, and knowledge visualization.

Scientific papers by staff appear under publications.