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RCDC

Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)


Table Published: February 13, 2012

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.

Consistent with the Administration’s emphasis on transparency, two separate columns are used to distinguish FY 2009 and FY 2010 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular NIH appropriations.

The table shows historical data for FY 2008 through FY 2011. The FY 2012-2013 estimates are based on RCDC actual data.


Total Number of Research/Disease Areas: 233

Click here for instructions on how to use the data table below.

Search Research/ Disease Areas
SEARCH RESEARCH/ DISEASE AREAS                             Print   Help
Research/Disease Areas
(Dollars in millions and rounded)
FY 2008ActualFY 2009Actual

(Non-ARRA)
FY 2009Actual

(ARRA)10/
FY 2010Actual

(Non-ARRA)
FY 2010Actual

(ARRA) 10/
FY 2011ActualFY 2012EstimatedFY 2013Estimated
Acute Respiratory Distress Syndrome $82 $103 $17 $110 $22 $96 $96 $96
Adolescent Sexual Activity N/A N/A N/A $80 $7 $69 $69 $69
Agent Orange & Dioxin $13 $13 $2 $11 $1 $8 $8 $8
Aging $1,965 $3,015 $554 $2,517 $443 $2,572 $2,562 $2,558
Alcoholism $452 $441 $75 $454 $65 $452 $454 $452
Allergic Rhinitis (Hay Fever) $6 $4 $1 $3 $1 $7 $7 $7
ALS $43 $43 $13 $47 $12 $44 $45 $44
Alzheimer's Disease 12/ $412 $457 $77 $450 $79 $448 $498 $449
American Indians / Alaska Natives $142 $169 $19 $151 $16 $136 $137 $137
Anorexia $7 $8 $2 $9 $2 $11 $11 $11
Anthrax $134 $102 $13 $118 $12 $87 $87 $87
Antimicrobial Resistance $228 $251 $52 $356 $66 $369 $369 $369
Aphasia $22 $22 $3 $21 $1 $21 $21 $21
Arctic $22 $28 $6 $34 $3 $28 $28 $28
Arthritis $232 $246 $65 $249 $59 $231 $225 $225
Assistive Technology $215 $249 $43 $250 $48 $250 $250 $250
Asthma $246 $284 $51 $244 $33 $221 $221 $221
Ataxia Telangiectasia $13 $13 $2 $12 $1 $13 $13 $13
Atherosclerosis $460 $495 $112 $544 $104 $475 $475 $474
Attention Deficit Disorder (ADD) $60 $71 $13 $66 $15 $55 $55 $55
Autism $118 $132 $64 $160 $58 $169 $169 $170
Autoimmune Disease $762 $879 $138 $856 $125 $869 $872 $872
Basic Behavioral and Social Science $1,149 $1,410 $206 $1,163 $198 $1,173 $1,171 $1,169
Batten Disease $5 $5 $2 $5 $1 $4 $4 $4
Behavioral and Social Science $3,215 $3,471 $582 $3,526 $603 $3,573 $3,553 $3,550
Biodefense 1/ $1,736 $1,755 $213 $1,794 $221 $1,803 $1,804 $1,805
Bioengineering $2,853 $3,155 $569 $3,166 $760 $3,303 $3,040 $3,030
Biotechnology $5,179 $5,619 $1,051 $5,682 $1,203 $5,823 $5,573 $5,562
Brain Cancer $194 $234 $42 $274 $36 $280 $280 $280
Brain Disorders $3,729 $3,538 $685 $3,847 $619 $3,864 $3,873 $3,870
Breast Cancer $726 $722 $111 $763 $61 $715 $712 $711
Burden of Illness $48 $43 $11 $48 $8 $40 $41 $40
Cancer $5,570 $5,629 $1,120 $5,823 $803 $5,448 $5,451 $5,446
Cardiovascular $2,027 $2,008 $396 $2,144 $398 $2,049 $2,050 $2,047
Cerebral Palsy $28 $21 $4 $19 $3 $23 $22 $22
Cervical Cancer $69 $84 $15 $93 $8 $119 $120 $120
Charcot-Marie-Tooth Disease $12 $14 $2 $15 $1 $13 $13 $13
Child Abuse and Neglect Research $30 $32 $5 $32 $5 $30 $30 $30
Childhood Leukemia $39 $47 $12 $55 $12 $59 $59 $59
Chronic Fatigue Syndrome (ME/CFS) $4 $5 $0 $6 $0 $6 $6 $6
Chronic Liver Disease and Cirrhosis $241 $274 $37 $284 $45 $303 $301 $301
Chronic Obstructive Pulmonary Disease $75 $96 $18 $118 $15 $108 $108 $108
Climate Change $4 $4 $2 $4 $2 $6 $6 $6
Climate-Related Exposures and Conditions 11/ $286 $179 $35 $188 $23 $155 $156 $155
Clinical Research $9,629 $10,336 $1,854 $10,720 $1,540 $10,503 $10,537 $10,528
Clinical Trials $3,562 $2,966 $485 $3,286 $356 $3,093 $3,102 $3,101
Colo-Rectal Cancer $274 $281 $48 $291 $26 $313 $311 $311
Comparative Effectiveness Research + $194 $246 $558 $320 $517 $511 $511
Complementary and Alternative Medicine $430 $513 $70 $521 $55 $442 $443 $443
Conditions affecting unborn children $81 $95 $8 $98 $21 $157 $157 $157
Contraception/Reproduction $473 $427 $65 $419 $56 $415 $415 $415
Cooley's Anemia $22 $21 $3 $20 $3 $20 $20 $20
Cost Effectiveness Research $49 $52 $16 $80 $14 $71 $69 $69
Crohn's Disease $51 $55 $14 $66 $12 $67 $67 $67
Cystic Fibrosis $90 $86 $13 $86 $13 $79 $79 $79
Dental/Oral and Craniofacial Disease $463 $490 $75 $497 $67 $501 $501 $499
Depression $402 $402 $48 $420 $50 $426 $419 $419
Diabetes 2/ $1,080 $1,030 $121 $1,046 $153 $1,076 $1,079 $1,078
Diagnostic Radiology $1,095 $976 $206 $1,073 $280 $1,071 $1,070 $1,068
Diethylstilbestrol (DES) $4 $4 $1 $4 $1 $3 $3 $3
Digestive Diseases $1,426 $1,538 $243 $1,657 $228 $1,698 $1,705 $1,704
Digestive Diseases - (Gallbladder) $7 $7 $1 $5 $0 $4 $4 $4
Digestive Diseases - (Peptic Ulcer) $14 $17 $3 $30 $3 $18 $18 $18
Down Syndrome $17 $18 $4 $22 $6 $20 $20 $20
Drug Abuse (NIDA Only) 3/ $1,007 $1,040 $135 $1,067 $125 $1,051 $1,052 $1,054
Duchenne/ Becker Muscular Dystrophy $22 $27 $6 $33 $5 $32 $32 $32
Dystonia $15 $16 $2 $14 $1 $13 $13 $13
Eating Disorders 4/ + $26 $5 $28 $4 $27 $27 $27
Emerging Infectious Diseases $2,098 $2,080 $307 $2,118 $350 $2,190 $2,193 $2,195
Emphysema $29 $28 $11 $23 $9 $22 $22 $22
Endometriosis $15 $15 $2 $15 $1 $14 $14 $14
Epilepsy $145 $128 $21 $134 $27 $152 $153 $152
Estrogen $245 $235 $34 $231 $23 $227 $226 $226
Eye Disease And Disorders Of Vision $796 $862 $129 $817 $110 $831 $832 $823
Facioscapulohumeral Muscular Dystrophy $3 $3 $2 $5 $1 $6 $6 $6
Fetal Alcohol Syndrome $34 $34 $7 $33 $5 $36 $36 $36
Fibroid Tumors (Uterine) $16 $18 $2 $12 $2 $12 $12 $12
Fibromyalgia $12 $11 $2 $9 $0 $11 $11 $11
Food Allergies $0 N/A N/A + + $33 $33 $33
Food Safety $244 $262 $37 $290 $35 $287 $286 $287
Fragile X Syndrome $26 $27 $5 $25 $4 $29 $29 $29
Frontotemporal Dementia (FTD) $17 $22 $2 $18 $1 $23 $23 $23
Gene Therapy $249 $221 $28 $248 $32 $248 $249 $248
Gene Therapy Clinical Trials $16 $11 $0 $14 $0 $14 $14 $14
Genetic Testing $383 $316 $76 $298 $121 $270 $270 $270
Genetics $6,872 $7,278 $1,676 $7,473 $1,440 $7,223 $7,260 $7,239
Global Warming Climate Change $1 $3 $1 $2 $2 $5 $5 $5
Headaches N/A N/A N/A $18 $1 $21 $20 $20
Health Disparities 5/ $2,614 $2,806 $434 $2,728 $351 $2,718 $2,727 $2,724
Health Services $743 $1,102 $316 $1,143 $334 $1,172 $1,164 $1,163
Heart Disease $1,217 $1,202 $227 $1,329 $235 $1,236 $1,239 $1,237
Heart Disease - Coronary Heart Disease $367 $426 $98 $457 $80 $437 $438 $437
Hematology $894 $908 $151 $961 $141 $1,006 $1,009 $1,008
Hepatitis $180 $178 $23 $204 $25 $208 $208 $208
Hepatitis - A $6 $4 $0 $4 $0 $4 $4 $4
Hepatitis - B $53 $51 $6 $66 $4 $58 $58 $58
Hepatitis - C $93 $97 $12 $100 $12 $114 $113 $113
HIV/AIDS 6/ $2,928 $3,019 $319 $3,085 $322 $3,059 $3,075 $3,075
Hodgkin's Disease $16 $26 $1 $24 $1 $20 $20 $20
Homelessness $13 $16 $3 $15 $3 $9 $9 $9
Homicide and Legal Interventions * $2 $1 $1 $0 $1 $1 $1
HPV and/or Cervical Cancer Vaccines $19 $25 $2 $25 $2 $24 $24 $24
Human Fetal Tissue 7/ $40 $41 $22 $55 $24 $66 $66 $66
Human Genome $1,259 $1,775 $566 $1,904 $598 $1,907 $1,914 $1,910
Huntington's Disease $51 $57 $12 $65 $7 $56 $56 $56
Hyperbaric Oxygen $4 $3 $0 $2 $0 $2 $2 $2
Hypertension $263 $266 $41 $251 $50 $240 $241 $241
Immunization $1,734 $1,773 $191 $1,798 $231 $1,756 $1,753 $1,755
Infant Mortality/ (LBW) $246 $246 $32 $273 $53 $286 $286 $286
Infectious Diseases $3,575 $3,627 $526 $3,890 $568 $3,883 $3,885 $3,885
Infertility $73 $75 $17 $76 $16 $74 $74 $74
Inflammatory Bowel Disease $81 $91 $22 $106 $19 $113 $114 $114
Influenza $204 $316 $46 $308 $88 $272 $271 $271
Injury - Childhood Injuries $26 $33 $3 $36 $3 $33 $33 $33
Injury - Trauma - (Head and Spine) $150 $161 $33 $179 $31 $166 $167 $166
Injury - Traumatic brain injury $59 $71 $15 $85 $9 $81 $82 $81
Injury - Unintentional Childhood Injury $15 $19 $1 $22 $1 $20 $20 $20
Injury (total) Accidents/Adverse Effects $299 $340 $58 $372 $46 $356 $356 $355
Interstitial Cystitis $10 $11 $1 $12 $1 $13 $13 $13
Kidney Disease $523 $570 $85 $552 $98 $557 $558 $558
Lead Poisoning $9 $11 $3 $11 $1 $10 $10 $10
Liver Cancer $89 $94 $12 $102 $10 $74 $74 $74
Liver Disease $562 $572 $79 $627 $85 $623 $626 $626
Lung $1,211 $1,265 $234 $1,269 $207 $1,278 $1,278 $1,277
Lung Cancer $169 $178 $36 $201 $22 $221 $221 $221
Lupus $126 $115 $19 $112 $15 $106 $105 $105
Lyme Disease $22 $25 $5 $24 $5 $28 $28 $28
Lymphoma $193 $184 $22 $195 $14 $199 $199 $199
Macular Degeneration $135 $85 $8 $104 $9 $105 $105 $103
Malaria $132 $110 $11 $134 $14 $145 $147 $147
Malaria Vaccine $32 $34 $3 $41 $4 $39 $39 $39
Mental Health $2,086 $2,129 $382 $2,246 $334 $2,275 $2,263 $2,262
Mental Retardation (Intellectual and Developmental Disabilities (IDD)) $350 $281 $94 $311 $87 $333 $334 $334
Methamphetamine $67 $69 $13 $73 $14 $70 $70 $70
Migraines N/A N/A N/A $15 N/A $16 $16 $16
Mind and Body $567 $494 $90 $549 $81 $533 $490 $490
Minority Health 5/ $2,396 $2,592 $378 $2,526 $312 $2,504 $2,512 $2,510
Mucopolysaccharidoses (MPS) $7 $7 $0 $8 $0 $10 $10 $10
Multiple Sclerosis $169 $137 $25 $133 $18 $122 $121 $121
Muscular Dystrophy $56 $66 $17 $74 $12 $75 $75 $75
Myasthenia Gravis $9 $9 $3 $8 $3 $9 $9 $9
Myotonic Dystrophy $9 $9 $4 $10 $2 $9 $10 $10
Nanotechnology 8/ $304 $343 $73 $435 $76 $409 $410 $409
Networking and Information Technology R&D 8/ $911 $1,174 $168 $647 $248 $551 $554 $552
Neuroblastoma $0 N/A N/A + + $25 $26 $25
Neurodegenerative $1,621 $1,553 $262 $1,571 $243 $1,622 $1,621 $1,616
Neurofibromatosis $14 $17 $2 $24 $1 $23 $23 $23
Neuropathy $121 $119 $13 $121 $10 $146 $145 $145
Neurosciences $5,224 $5,320 $848 $5,515 $794 $5,548 $5,535 $5,523
Nutrition $1,391 $1,400 $205 $1,435 $208 $1,411 $1,389 $1,386
Obesity $664 $745 $117 $824 $147 $830 $829 $827
Organ Transplantation $175 $139 $32 $150 $37 $164 $164 $164
Orphan Drug $645 $441 $118 $512 $89 $749 $751 $750
Osteogenesis Imperfecta $5 $5 $1 $8 $4 $9 $9 $9
Osteoporosis $183 $198 $21 $181 $23 $179 $178 $178
Otitis Media $18 $15 $7 $19 $2 $15 $15 $15
Ovarian Cancer $96 $102 $13 $122 $10 $138 $138 $138
Paget's Disease $1 $1 $1 $1 $0 $1 $1 $1
Pain Conditions - Chronic $279 $333 $53 $360 $44 $386 $358 $357
Pancreatic Cancer $0 N/A N/A + + $112 $113 $112
Parkinson's Disease $152 $162 $24 $154 $18 $151 $151 $151
Patient Safety N/A N/A N/A $859 $263 $839 $838 $836
Pediatric $2,771 $2,996 $505 $3,286 $479 $3,277 $3,281 $3,272
Pediatric AIDS 6/ $241 $227 $20 $216 $15 $228 $228 $229
Pediatric Research Initiative $209 $214 $256 $308 $148 $362 $363 $361
Pelvic Inflammatory Disease $3 $3 $1 $4 $1 $4 $4 $4
Perinatal - Birth - Preterm (LBW) $197 $177 $23 $183 $47 $214 $214 $214
Perinatal - Neonatal Respiratory Distress Syndrome $18 $31 $5 $31 $3 $37 $37 $37
Perinatal Period - Conditions Originating in Perinatal Period $449 $470 $65 $542 $84 $498 $498 $497
Pick's Disease $2 $2 $0 $2 $0 $3 $3 $3
Pneumonia $93 $108 $15 $93 $17 $117 $118 $118
Pneumonia & Influenza $295 $392 $58 $396 $102 $382 $381 $381
Polycystic Kidney Disease $41 $38 $7 $35 $6 $42 $43 $42
Prescription Drug Abuse N/A N/A N/A $29 $7 $28 $29 $29
Prevention $4,623 $5,332 $844 $5,983 $849 $5,929 $5,917 $5,914
Prostate Cancer $290 $310 $47 $331 $31 $284 $285 $285
Psoriasis $8 $13 $3 $13 $3 $10 $10 $10
Rare Diseases $0 N/A N/A + + $3,527 $3,537 $3,534
Regenerative Medicine $723 $799 $144 $820 $142 $824 $827 $825
Rehabilitation $403 $404 $75 $458 $93 $459 $453 $452
Rett Syndrome $9 $9 $4 $13 $2 $12 $12 $12
Reye's Syndrome $0 $0 $0 $0 $0 $0 - -
Rural Health $170 $186 $42 $207 $33 $211 $211 $211
Schizophrenia $249 $265 $85 $276 $63 $264 $265 $264
Scleroderma $20 $21 $2 $19 $2 $25 $25 $25
Screening And Brief Intervention For Substance Abuse N/A N/A N/A $26 $4 $30 $30 $30
Septicemia $95 $92 $19 $90 $17 $91 $91 $90
Sexually Transmitted Diseases/Herpes $245 $250 $43 $250 $38 $259 $260 $260
Sickle Cell Disease $80 $63 $14 $73 $12 $65 $65 $65
Sleep Research $225 $217 $33 $226 $22 $232 $230 $229
Small Pox $94 $94 $4 $92 $5 $41 $41 $41
Smoking and Health $310 $329 $78 $336 $55 $360 $361 $360
Spina Bifida $15 $14 $3 $12 $6 $11 $11 $11
Spinal Cord Injury $80 $80 $14 $87 $16 $78 $78 $78
Spinal Muscular Atrophy $10 $11 $3 $16 $3 $19 $19 $19
Stem Cell Research $938 $1,044 $187 $1,099 $187 $1,179 $1,185 $1,182
Stem Cell Research - Embryonic - Human $88 $120 $23 $126 $40 $123 $124 $123
Stem Cell Research - Embryonic - Non-Human $150 $148 $29 $175 $20 $165 $166 $165
Stem Cell Research - Nonembryonic - Human $297 $339 $58 $341 $74 $395 $396 $396
Stem Cell Research - Nonembryonic - Non-Human $497 $550 $88 $570 $74 $620 $622 $621
Stem Cell Research - Umbilical Cord Blood/ Placenta $46 $49 $10 $42 $8 $41 $41 $41
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $38 $42 $9 $40 $7 $36 $36 $36
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $9 $10 $1 $5 $1 $10 $10 $10
Stroke $296 $329 $54 $337 $54 $317 $316 $316
Substance Abuse 9/ $1,763 $1,653 $245 $1,674 $216 $1,623 $1,626 $1,625
Substance Abuse Prevention N/A N/A N/A $43 $10 $44 $44 $44
Sudden Infant Death Syndrome $29 $22 $6 $25 $2 $23 $23 $23
Suicide $39 $36 $15 $36 $4 $49 $49 $49
Suicide Prevention N/A N/A N/A $17 $2 $25 $25 $25
Teenage Pregnancy $21 $23 $5 $22 $5 $19 $19 $19
Temporomandibular Muscle/Joint Disorder (TMJD) $19 $15 $1 $16 $1 $18 $18 $18
Tobacco $311 $331 $78 $339 $55 $362 $363 $363
Topical Microbicides $102 $92 $7 $84 $5 $104 $104 $105
Tourette Syndrome $8 $7 $3 $7 $0 $5 $5 $5
Transmissible Spongiform Encephalopathy (TSE) $44 $43 $4 $48 $3 $46 $46 $46
Transplantation $519 $571 $94 $574 $109 $592 $592 $592
Tuberculosis $142 $189 $27 $189 $35 $209 $209 $210
Tuberculosis Vaccine $18 $15 $3 $13 $3 $17 $17 $17
Tuberous Sclerosis $20 $20 $3 $20 $2 $20 $20 $20
Underage Drinking N/A N/A N/A $75 $5 $77 $77 $77
Underage Drinking – Prevention & Treatment (NIAAA Only) N/A N/A N/A $56 $2 $57 $57 $57
Urologic Diseases $534 $578 $81 $563 $56 $542 $543 $543
Uterine Cancer $16 $25 $4 $26 $4 $40 $40 $40
Vaccine Related $1,632 $1,593 $185 $1,737 $222 $1,717 $1,714 $1,716
Vaccine related (AIDS) 6/ $556 $561 $35 $535 $27 $550 $545 $556
Vector-Borne Diseases $417 $401 $66 $426 $68 $466 $466 $467
Violence Against Women $45 $39 $2 $36 $2 $34 $34 $34
Violence Research $183 $182 $21 $174 $19 $156 $156 $156
Vulvodynia + $1 $1 $2 $1 $2 $2 $2
West Nile Virus $39 $59 $7 $46 $6 $65 $65 $65
Women's Health 5/ $3,514 $3,725 $506 $3,691 $449 $3,891 $3,894 $3,892
Youth Violence $115 $111 $12 $102 $10 $87 $87 $87
Youth Violence Prevention N/A N/A N/A $32 $2 $26 $26 $26
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the actual FY 2009 or FY 2010 level reported.
1/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at http://www.niaid.nih.gov/topics/biodefenserelated/pages/default.aspx.
2/ Includes research funded from the Type 1 diabetes appropriation of $150,000,000. These are project listings only.
3/ Reporting for this category does not follow the standard RCDC process. Spending is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements (Only NIDA). More information on this area is available at http://www.drugabuse.gov/drugs-abuse.
4/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
5/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex and not currently compatible with the RCDC system.
6/ Reporting for this category does not follow the standard RCDC process. These are project listings only and non-project or other support costs associated with the annual total for the category are not included. More information on this area is available at http://www.oar.nih.gov/.
7/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings.
8/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that were based on preliminary funding support information.
9/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at http://www.drugabuse.gov/drugs-abuse.
10/ Separate columns are used to distinguish FY 2009 and FY 2010 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular annual NIH appropriations.
11/ Title revised from "Health Effects of Climate Change" to more accurately reflect the content of the research conducted and facilitate reporting spending data in response to requests tracking climate change adaptation.
12/ The FY 2013 estimated amount for the Alzheimer’s disease research does not include $80 million budgeted in FY 2013 in the proposed Prevention and Public Health Fund allocation to the DHHS General Departmental Management budget. The total Alzheimer’s disease research expenditures including these resources would be $529 million in FY 2013.

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