The NIH Guide Notice (NOT-AI-12-036) Modification: Updates to HIV/AIDS Clinical Network Leadership Group (LG) Statistical and Data Management Center (SDMC) Components, Review Criteria and Additional Review Criteria for RFA-AI-12-001, RFA-AI-12-004, RFA-AI-12-008, RFA-AI-12-011 and RFA-AI-12-012 has been published. See the notice.
The NIH Guide Notice (NOT-AI-12-035) “Clarification on NIH HIV/AIDS Clinical Network Responsibilities for the Use of Antibody-based Therapies for the Prevention and Treatment of HIV Infection” has been published. See the notice.
Restructuring the NIAID Clinical Trials Networks
NIAID is looking to expand upon the success of its six current HIV/AIDS clinical trials networks to create an infrastructure capable of performing both HIV/AIDS research and research involving non-HIV/AIDS infectious diseases. The awards currently supporting the six HIV/AIDS networks are set to expire in 2013 and 2014.
Please check back regularly or subscribe for updates. We will post the latest news and information on the network restructuring initiative as it becomes available.
Funding Opportunities
Since January 2012, NIAID has issued a number of Funding Opportunity Announcements (FOAs) in connection with its efforts to revamp and expand its HIV/AIDS clinical research networks. The following are the FOAs that have been released:
- Clinical Trials Units (RFA issued April 10, 2012; applications accepted until January 29, 2013)
- Antibacterial Resistance (RFA issued Jan. 13, 2012; application deadline was June 1, 2012)
- HIV/AIDS and HIV-associated Infections in Pediatric and Maternal Populations (RFA issued Jan. 27, 2012; application deadline was Sept. 28, 2012)
- Integrated Strategies to Prevent HIV Infection (RFA issued Jan. 27, 2012; application deadline was Sept. 28, 2012)
- Microbicides to Prevent HIV Infection (RFA issued Jan. 27, 2012; application deadline was Sept. 28, 2012)
- Therapeutics for HIV/AIDS and HIV-associated Infections in Adults (RFA issued Jan. 27, 2012; application deadline was Sept. 28, 2012)
- Vaccines to Prevent HIV Infection (RFA issued Jan. 27, 2012; application deadline was Sept. 28, 2012)
Please check back routinely for updates on amendments or other changes to published RFAs.
Questions and Answers
The following are Questions and Answers related to the Funding Opportunity Announcements (FOAs) that NIAID has issued in connection with its clinical trials restructuring effort. If you would like to submit a question about any of the currently open FOAs, please click on the "Submit a Question" button on the right hand side of this page. We will do our best to address all appropriate, relevant questions in a timely fashion, and post them here.
NIAID Town Hall Meetings and Workshops
In April 2012, NIAID issued a Funding Opportunity Announcement (FOA) designed to solicit applications for the Clinical Trials Units (CTUs). To assist potential CTU applicants, NIAID will host three workshops focused on the grant application and review process. The first of these workshops will be held July 28–29, 2012, in Washington, D.C. The two remaining workshops are tentatively scheduled for Aug. 16–18, 2012, in Rio de Janeiro, Brazil, and Oct. 25–27, 2012, in Johannesburg, South Africa.
Additional information about the workshops, including registration and agenda, is now available online.
On March 7, 2011, NIAID hosted a public meeting at the Bethesda Marriott in Bethesda, Maryland, to discuss the development of a non-HIV/AIDS Leadership Group focused on bacterial antibiotic resistance, with the ability to rapidly address emerging infectious diseases.
On October 26, 2010, NIAID hosted a town hall meeting in Arlington, Virginia, to discuss the future of the HIV/AIDS Infectious Diseases Clinical Trials Networks. NIAID and its collaborating partners from the National Institutes of Health (NIH) presented key aspects of the new networks with a focus on potential changes in research priorities and network structure, opportunities for collaborations, and general information on the application process.
View meeting summaries and presentations from both meetings.
Other Forums for Feedback
NIAID has been using the AIDS.gov blog to communicate about the future direction of its clinical trials networks and to seek feedback from the interested public. All of NIAID’s blog posts on this topic can be found on www.AIDS.gov. Each of the posts that have appeared to date is noted below. We welcome your feedback.
- Restructuring NIAID's HIV/AIDS Clinical Trials Networks, June 10, 2010
- Future Priorities for NIAID’s HIV Prevention Research, June 21, 2010
- Looking Ahead: NIAID’s Future HIV/AIDS Therapeutics Priorities, June 30, 2010
- Future Directions for NIAID’s HIV Vaccine Clinical Research, July 16, 2010
- What's in it for Non-AIDS Infectious Diseases Researchers?, Oct. 21, 2010
- Future Directions-HIV Clinical Trials-Town Hall, Nov. 12, 2010
- Toward Defining the Non-HIV Infectious Diseases Leadership Group, Feb. 16, 2011
- The Future of the NIAID Clinical Trial Units, June 28, 2011
- Community Engagement in NIAID’s HIV/AIDS Clinical Trials Networks, Sept. 29, 2011
- NIAID Advances Efforts to Restructure Clinical Trials Networks with Funding Announcements, Feb. 3, 2012