Share
PrintGenome Technology Program
- Overview
- Related Information
- Reports
- Policies
- Funding Opportunities
- Advanced Sequencing Technology Awards
- Genome Technology Features
- Publications and Patents
- Staff
Genome Technology Program Overview
The Genome Technology program supports research to develop new methods, technologies and instruments that enable rapid, low-cost determination of DNA sequence, SNP genotyping (Genetic Variation Program) and functional genomics (broadly defined) experiments (Functional Analysis Program). Priorities include the refinement of current technologies to increase efficiency and decrease cost while maintaining or improving data quality, and the development of completely novel approaches to achieve orders-of-magnitude improvement. Integration of process steps is key to achieving these goals.
The program also supports and coordinates transfer of technology from developers to users, and promotes collaborative, multidisciplinary programs that closely integrate research projects at academic and industrial laboratories.
The National Human Genome Research Institute (NHGRI) participates in numerous trans-NIH efforts, including one on bioengineering research. The development of integrated concepts and tools for genomic research benefits from bioengineering research, methods and approaches. NHGRI supports bioengineering research through grants made in response to NHGRI program announcements and requests for application, and through NHGRI participation in trans-NIH bioengineering program announcements, such as the Bioengineering Research Grants (BRG) and Bioengineering Research Partnerships (BRP) programs and other Funding Opportunities that are listed below.
Genome Technology Program Related Information
Genome Technology Program Reports
- Sequencing and Re-Sequencing the Biome! July 2002
- Sequencing Technology Workshop May 13, 1998
- Sequencing Variation Workshop March 31-April 1, 1997
- Functional Analysis Workshop December 2-3, 1997
Genome Technology Program Policies
- Principles and Guidelines for Recipients of NIH Research Grants and Contracts on Obtaining and Disseminating Biomedical Research Resources: Final Notice [ott.od.nih.gov]
Genome Technology Program Funding Opportunities
NHGRI Funding Opportunities
RFA-HG-10-014 [grants.nih.gov]: Revolutionary Genome Sequencing Technologies The $1000 Genome (SBIR [R43/R44])
Letters of intent are due September 17, 2012, and applications are due October 17, 2012
RFA-HG-10-013 [grants.nih.gov]: Revolutionary Genome Sequencing Technologies The $1000 Genome (R21)
Letters of intent are due September 17, 2012, and applications are due October 17, 2012.
RFA-HG-10-012 [grants.nih.gov]: Revolutionary Genome Sequencing Technologies The $1000 Genome (R01)
Letters of intent are due September 17, 2012, and applications are due October 17, 2012
PAR-10-202 [grants.nih.gov]: Centers of Excellence in Genomic Science (CEGS) (P50)
This is NHGRI's signature Centers program. Forward-looking technology development is included in the goals of the program.
Many other solicitations are appropriate means for submitting genomic technology development grant applications. Please see NHGRI's Funding Opportunities page at NHGRI Funding Opportunities
Genome Technology Program Advanced Sequencing Technology Awards
In 2004, NHGRI initiated a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.
- Advanced Sequencing Technology Awards 2012
- New NIH/NHGRI grants to harness nanoscale technologies to cut DNA sequencing costs
September 14, 2012 News Release
- NHGRI funds development of revolutionary
DNA sequencing technologies
August 22, 2011 News Release
- Advanced Sequencing Technology Awards 2010
- NHGRI funds development of
third generation DNA sequencing technologies
September 13, 2010 News Release
- Advanced Sequencing Technology Awards 2009
- NHGRI Uses Recovery Act Funds to Accelerate
Genome Research to Improve Human Health
October 8, 2009 Online News Feature - Advanced Sequencing Technology Awards 2008
-
NHGRI Seeks DNA Sequencing Technologies Fit for Routine Laboratory and Medical Use
August 20, 2008 News Release - Advanced Sequencing Technology Awards 2007
- New Grants Bolster Efforts to Generate Faster and Cheaper Tools for DNA Sequencing
August 1, 2007 News Release - NHGRI Aims to Make DNA Sequencing Faster, More Cost Effective
October 4, 2006 News Release - Advanced Sequencing Technology Awards 2005
- NHGRI Expands Effort to Revolutionize Sequencing Technologies
August 8, 2005 Release - Advanced Sequencing Technology Awards 2004
- NHGRI Seeks Next Generation of Sequencing Technologies
October 14, 2004 Release
Genome Technology Features
- July 2011: Genome Advance of the Month - Proteus: Discovering the tiniest disease-causing flaws - and improving sequencing technologies
- February 7, 2011: The Road to the $1000 Genome Via Nanopores - A Roundup of Sequencing Technology Developments
- August 2, 2010: The Road to the $1000 Genome - A Roundup of Sequencing Technology Developments
Genome Technology Program Bibliography: Publications and Patents
NHGRI launched an ambitious program in 2004 to reduce the cost of full mammalian genome sequencing initially by 100-fold and subsequently by an additional 100-fold, aiming ultimately at about $1,000. Below, listed by Principal Investigator, are citations and links to many of the articles and patents resulting from this program and closely related research.
Genome Technology Program Publications and Patents
To view this PDF you will need Adobe Reader. 
Genome Technology Program Staff
Program Directors
Jeffery Schloss, Ph.D.
E-mail: schlossj@exchange.nih.gov
Bradley A. Ozenberger, Ph.D.
E-mail: bozenberger@mail.nih.gov
Mark Guyer, Ph.D.
E-mail: guyerm@exchange.nih.gov
Address
National Human Genome Research Institute
National Institutes of Health
5635 Fishers Lane
Suite 4076, MSC 9305
Bethesda, MD 20892-9305
Phone: (301) 496-7531
Fax: (301) 480-2770
Last Updated: September 14, 2012
