SKIP ALL NAVIGATION SKIP TO SUB MENU
National Cancer Institute at the National Institutes of Health. Website is www.cancer.gov
Technology Transfer Center. The National Institutes of Health ... Turning Discovery Into Health
Technology Transfer Center of the National Cancer Institute

Taxol®

Taxol bottle

NIH's (NCI) Contribution

  • Identified paclitaxel from the Pacific yew tree bark by screening natural products for antitumor activity
  • Conducted pre-clinical testing and clinical trials
  • Developed alternative drug administration methods

Bristol-Myers Squibb's Contribution

  • Developed supplies of Taxol® by licensing Taxol semisynthesis technology from Florida State University
  • Collaborated in the clinical development with the NIH

Results of Collaboration

  • Product -- Anti-cancer drug Taxol®
  • FDA approved Taxol® for the treatment of breast, ovarian, lung cancer and Kaposi's sarcoma
  • Over 1 million patients received treatment with Taxol® (paclitaxel)