The Chemistry Support Group is a component of the Molecular Discovery Program, housed within both the Chemical Biology Laboratory in Frederick and the National Center for Advancing Translational Sciences (NCATS) in Rockville. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community.
The facility’s capabilities include:
- Providing expertise, consultation and experience in areas of chemical synthesis
and purification.
- Providing custom synthesis and support for the development of small molecule tools
or the synthesis of known ligands or probes which are not commercially available.
- Synthesis of materials for pre-clinical investigations.
- Support for small-molecule drug discovery through optimization of leads identified
in high throughput screens.
- Collaborative short-term sabbatical-type opportunities for post-doctoral fellows
who wish to gain synthetic chemistry experience.
The Chemistry Support Group provides a means to access chemical technology for those
groups within the NCI Intramural community which would not otherwise be capable
of exploring these aspects of their research.