medication-assisted treatment for substance use disorders

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Methadone

Methadone is a synthetic opioid that blocks the effects of heroin and other prescription drugs containing opiates. Used successfully for more than 40 years, methadone has been shown to eliminate withdrawal symptoms and relieve drug cravings from heroin and prescription opiate medications.

GAO Report: Methadone-associated overdose deaths. Factors Contributing to Increased Deaths and Efforts to Prevent Them, March 2009 (PDF, 2MB)
CDC Methadone Maintenance Treatment Fact Sheet
Connecticut Methadone Medical Maintenance Pilot Project, Final Report to the Connecticut Department of Mental Health and Addiction, May 2001 (PDF, 240 KB)
Elimination of Methadone Benefits in Oregon Health Plan and Its Effects on Patients pyschiatryonline.org, Volume 57 | Issue 5, May 2006
Methadone-Associated Mortality: Report of a National Assessment, SAMHSA, May 2003
Methadone Mortality Reassessment, July 20, 2007
Methadone Symposium, Part 1, Mt Sinai Journal of Medicine, October 2000
Methadone Symposium, Part 2, Mt Sinai Journal of Medicine, January 2001
NIH Consensus Statement on Effective Treatment of Opiate Addiction, November 1997

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Department of Health and Human Services
Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment
Division of Pharmacologic Therapies
1 Choke Cherry Road • Room 2-1075 • Rockville, MD 20857 • 240-276-2700 • otp@samhsa.hhs.gov