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Breast Cancer Treatment Effectiveness in Older Women Direct link to this project

Project Staff:
  • Project Leader: Rebecca Silliman, Boston University Medical Center
  • Investigator: Ann Geiger, Wake Forest University
  • Investigator: Diana Buist, Group Health
  • Investigator: Feifei Wei, HealthPartners Research Foundation
  • Investigator: Floyd Frost, Lovelace Clinic Foundation
  • Investigator: Marianne Ulcickas Yood, Henry Ford Health System
  • Investigator: Soe Soe Thwin, Boston University Medical Center
  • Investigator: Terry Field, Meyers Primary Care Institute
  • Investigator: Timothy L. Lash, Boston University Medical Center
  • Investigator: Virginia Quinn, KP Southern California
Funding Source: National Cancer Institute
Funding Start Date: 2/1/2003
Area(s) of Research: Epidemiology & Surveillance; Health Disparities; Health Services; Outcomes; Quality of Care
Tumor Site(s): Breast
Description: minus sign Hide

Dr. Rebecca Silliman (Boston University), a member of the CRN Academic Liaison Committee, led this large-scale cohort study of the care and outcomes of 1,859 older women with breast cancer at six CRN sites. By reviewing medical records and using administrative data, information was collected on initial surgery, adjuvant treatments, long-term surveillance, and recurrence and mortality outcomes. The team compared the effectiveness of different treatment and surveillance patterns, and identified the characteristics of providers, tumors, and patients associated with various treatment choices. The study found that less-than-standard treatment is associated with increased rates of recurrence and breast cancer-specific mortality, while mammography surveillance during the first five years after diagnosis is associated with a reduced rate of breast cancer mortality.

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